Timo Rückert
@timorckert.bsky.social
Immunologists with a focus on clonality & NK cells - Postdoc, Romagnani Lab, Charité Universitätsmedizin Berlin [he/him/his]
We are looking for motivated PhD candidates to study NK cell clonality and memory :)
Apply by December 10
Apply by December 10
Join us at Charité University and the IMPRS-IDI Graduate Program in Berlin to unravel NK cell clonality and memory! We are looking for motivated PhD candidates who are passionate about immunology. @romagnanilab.bsky.social
@timorckert.bsky.social
Apply now 👉 www.imprs-idi.org/home/
@timorckert.bsky.social
Apply now 👉 www.imprs-idi.org/home/
November 14, 2025 at 2:44 PM
We are looking for motivated PhD candidates to study NK cell clonality and memory :)
Apply by December 10
Apply by December 10
Reposted by Timo Rückert
You like engineering T cells, but you are missing the right flavor?
Check out 'one-pot' PASTA recipe 🔥🍝: www.biorxiv.org/content/10.1101/2025.09.10.675267v1
We combined a unique mix of CRISPR knock-in with serine integrases for easy-to-adopt
𝐏rogrammable
𝐀nd
𝐒ite-specific
𝐓ransgene
𝐀ddition
🧪
Check out 'one-pot' PASTA recipe 🔥🍝: www.biorxiv.org/content/10.1101/2025.09.10.675267v1
We combined a unique mix of CRISPR knock-in with serine integrases for easy-to-adopt
𝐏rogrammable
𝐀nd
𝐒ite-specific
𝐓ransgene
𝐀ddition
🧪
Versatile and efficient non-viral integration of large transgenes in human T cells via CRISPR knock-in and engineered integrases
Current gene transfer methods often lack the precision, versatility, or efficiency when integrating large transgenes, limiting the ability to engineer therapeutic T-cells with more complex payloads. H...
www.biorxiv.org
September 19, 2025 at 5:30 AM
You like engineering T cells, but you are missing the right flavor?
Check out 'one-pot' PASTA recipe 🔥🍝: www.biorxiv.org/content/10.1101/2025.09.10.675267v1
We combined a unique mix of CRISPR knock-in with serine integrases for easy-to-adopt
𝐏rogrammable
𝐀nd
𝐒ite-specific
𝐓ransgene
𝐀ddition
🧪
Check out 'one-pot' PASTA recipe 🔥🍝: www.biorxiv.org/content/10.1101/2025.09.10.675267v1
We combined a unique mix of CRISPR knock-in with serine integrases for easy-to-adopt
𝐏rogrammable
𝐀nd
𝐒ite-specific
𝐓ransgene
𝐀ddition
🧪
Must read! Super exciting work and innovative approach.
Excited to share a new preprint from the lab with @ryandhindsa.bsky.social ! www.biorxiv.org/content/10.1...
Led by @sherrynyeo.bsky.social, @erinmayc.bsky.social, and friends, we continue our journey to find viral DNA in our favorite place-- the overlooked and discarded reads in existing data! 1/
Led by @sherrynyeo.bsky.social, @erinmayc.bsky.social, and friends, we continue our journey to find viral DNA in our favorite place-- the overlooked and discarded reads in existing data! 1/
July 23, 2025 at 3:17 PM
Must read! Super exciting work and innovative approach.
Reposted by Timo Rückert
Trying a slightly new model (for us at least) of #openscience. With @ronanchaligne.bsky.social and @karolisk.bsky.social, we pitted 10x Genomics Chromium GEM-X against Illumina PIPseq V head-to-head to understand these two platforms for single-cell genomics. Some thoughts off the bleeding edge: /1
a baby is eating a piece of food while sitting on the ground .
ALT: a baby is eating a piece of food while sitting on the ground .
media.tenor.com
March 14, 2025 at 1:29 PM
Trying a slightly new model (for us at least) of #openscience. With @ronanchaligne.bsky.social and @karolisk.bsky.social, we pitted 10x Genomics Chromium GEM-X against Illumina PIPseq V head-to-head to understand these two platforms for single-cell genomics. Some thoughts off the bleeding edge: /1
Reposted by Timo Rückert
Happy to share that the preprint to our new scATAC-seq multiplexing method, MULTI-ATAC, is officially online:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reducing batch effects in single cell chromatin accessibility measurements by pooled transposition with MULTI-ATAC
Large-scale scATAC-seq experiments are challenging because of their costs, lengthy protocols, and confounding batch effects. Several sample multiplexing technologies aim to address these challenges, b...
www.biorxiv.org
February 20, 2025 at 9:48 PM
Happy to share that the preprint to our new scATAC-seq multiplexing method, MULTI-ATAC, is officially online:
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Timo Rückert
Bluetorial: Avoiding becoming et al.
I decided not to do a postdoc with a Nobel laureate for personal reasons, but this decision had unanticipated benefits for my career.
I decided not to do a postdoc with a Nobel laureate for personal reasons, but this decision had unanticipated benefits for my career.
a cartoon says hey everybody an old man 's talking while bart simpson looks on
ALT: a cartoon says hey everybody an old man 's talking while bart simpson looks on
media.tenor.com
December 30, 2024 at 2:53 PM
Bluetorial: Avoiding becoming et al.
I decided not to do a postdoc with a Nobel laureate for personal reasons, but this decision had unanticipated benefits for my career.
I decided not to do a postdoc with a Nobel laureate for personal reasons, but this decision had unanticipated benefits for my career.
Reposted by Timo Rückert
💥💥💥 !!! Please re-post !!! 💥💥💥
Hello Community,
We’re excited to announce that we’re moving to Groningen in January 2025 to embark on a new chapter in our research careers. For this, we need a house/flat and we hope to find a nice place with your help.
Hello Community,
We’re excited to announce that we’re moving to Groningen in January 2025 to embark on a new chapter in our research careers. For this, we need a house/flat and we hope to find a nice place with your help.
December 9, 2024 at 3:21 PM
💥💥💥 !!! Please re-post !!! 💥💥💥
Hello Community,
We’re excited to announce that we’re moving to Groningen in January 2025 to embark on a new chapter in our research careers. For this, we need a house/flat and we hope to find a nice place with your help.
Hello Community,
We’re excited to announce that we’re moving to Groningen in January 2025 to embark on a new chapter in our research careers. For this, we need a house/flat and we hope to find a nice place with your help.
I'm incredibly honored to have received this recognition. A heartfelt thank you to everyone involved in making the evening so special :)
Huge congratulations to @timorckert.bsky.social on receiving the Pettenkofer Prize for our work on human NK cell memory and clonality! A heartfelt thank you to Oliver Keppler and the Pettenkofer-Stiftung for the warm welcome and the wonderful ceremony!
December 3, 2024 at 10:10 AM
I'm incredibly honored to have received this recognition. A heartfelt thank you to everyone involved in making the evening so special :)
Reposted by Timo Rückert
A short intro to the many new followers gained at 🦋:
🧪🔬we are a diverse team of researchers driven by curiosity, dedicated to understanding immune regulation in disease & cancer & exploring new strategies for immunotherapies 🩺⚕️
❤️ all things spatial; DCs, T cells, NK cells & single cell analyses.
🧪🔬we are a diverse team of researchers driven by curiosity, dedicated to understanding immune regulation in disease & cancer & exploring new strategies for immunotherapies 🩺⚕️
❤️ all things spatial; DCs, T cells, NK cells & single cell analyses.
November 20, 2024 at 6:48 AM
A short intro to the many new followers gained at 🦋:
🧪🔬we are a diverse team of researchers driven by curiosity, dedicated to understanding immune regulation in disease & cancer & exploring new strategies for immunotherapies 🩺⚕️
❤️ all things spatial; DCs, T cells, NK cells & single cell analyses.
🧪🔬we are a diverse team of researchers driven by curiosity, dedicated to understanding immune regulation in disease & cancer & exploring new strategies for immunotherapies 🩺⚕️
❤️ all things spatial; DCs, T cells, NK cells & single cell analyses.
To introduce myself and what I do: in my PhD @romagnanilab.bsky.social, I found that human NK cells maintain clonal immune memory to CMV infection www.nature.com/articles/s41...
Clonal expansion and epigenetic inheritance of long-lasting NK cell memory - Nature Immunology
Here, the authors use single-cell multiomics and profiling of mitochondrial mutations as endogenous barcodes to show that human adaptive NK cells induced by CMV persist as clonal expansions that inher...
www.nature.com
November 17, 2024 at 6:02 PM
To introduce myself and what I do: in my PhD @romagnanilab.bsky.social, I found that human NK cells maintain clonal immune memory to CMV infection www.nature.com/articles/s41...
Reposted by Timo Rückert
To populate my Bluesky and people know what I do: I am an MD turned immunology "basic" researcher. In the past I did adoptive T cell therapy and then fate mapping in the Buchholz lab in Munich:
CD8+ T cells in MCMV:
www.nature.com/articles/s41...
CD8+ T cells in MCMV:
www.nature.com/articles/s41...
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection - Nature Immunology
T cell memory formation is often described as occurring during the chronic phases of infection. Buchholz and colleagues use the phenomenon of ‘memory inflation’ following cytomegalovirus infection to ...
www.nature.com
November 13, 2024 at 4:25 PM
To populate my Bluesky and people know what I do: I am an MD turned immunology "basic" researcher. In the past I did adoptive T cell therapy and then fate mapping in the Buchholz lab in Munich:
CD8+ T cells in MCMV:
www.nature.com/articles/s41...
CD8+ T cells in MCMV:
www.nature.com/articles/s41...
Reposted by Timo Rückert
🚨 We’re hiring! 🚨
Join the Gaebler & Ibrahim Labs for an exciting postdoc position at the intersection of virology & gene regulation! Help us uncover mechanisms behind HIV latency using cutting-edge genome engineering. More info: www.nature.com/naturecareer...
Join the Gaebler & Ibrahim Labs for an exciting postdoc position at the intersection of virology & gene regulation! Help us uncover mechanisms behind HIV latency using cutting-edge genome engineering. More info: www.nature.com/naturecareer...
Postdoctoral Scientist (d/f/m) in Life Sciences/Genetics - Berlin (DE) job with Berlin Institute of Health in der Charité (BIH) | 12831190
The mission of the Berlin Institute of Health at Charité (BIH) is medical translation: transferring biomedical research findings into novel approac...
www.nature.com
November 4, 2024 at 8:06 PM
🚨 We’re hiring! 🚨
Join the Gaebler & Ibrahim Labs for an exciting postdoc position at the intersection of virology & gene regulation! Help us uncover mechanisms behind HIV latency using cutting-edge genome engineering. More info: www.nature.com/naturecareer...
Join the Gaebler & Ibrahim Labs for an exciting postdoc position at the intersection of virology & gene regulation! Help us uncover mechanisms behind HIV latency using cutting-edge genome engineering. More info: www.nature.com/naturecareer...