Poul Sørensen
@thepou1.bsky.social
Danish biotech start-up builder living in Paris | RNA Tx & immunotherapy aficionado | Family barista | Kongeblå & Gooner
Reposted by Poul Sørensen
Novel Novartis Malaria Drug Shows Promise to Become New Asset Against Resistant Strains
https://medcitynews.com/2025/11/novartis-malaria-ganaplacide-lumefantrine-ganlum-drug-resistance-infectious-disease-nvs/
Novel Novartis Malaria Drug Shows Promise to Become New Asset Against Resistant Strains
Phase 3 results for the Novartis malaria drug “GanLum” show it was comparable to the standard of care and led to cure rates that top the threshold recommended by the World Health Organization. If approved, this new combination drug would become the first novel malaria therapy in more than 25 years.
medcitynews.com
November 13, 2025 at 12:51 AM
Novel Novartis Malaria Drug Shows Promise to Become New Asset Against Resistant Strains
https://medcitynews.com/2025/11/novartis-malaria-ganaplacide-lumefantrine-ganlum-drug-resistance-infectious-disease-nvs/
This year’s #NobelPrize celebrates breakthroughs in immune tolerance. Curious how it shapes #immunotherapy? Join us in Aarhus on Nov 27 for the annual Aarhus Immunotherapy Symposium with a stellar lineup of speakers ! conferences.au.dk/ais
Aarhus Immunotherapy Symposia
conferences.au.dk
November 8, 2025 at 9:38 PM
This year’s #NobelPrize celebrates breakthroughs in immune tolerance. Curious how it shapes #immunotherapy? Join us in Aarhus on Nov 27 for the annual Aarhus Immunotherapy Symposium with a stellar lineup of speakers ! conferences.au.dk/ais
Reposted by Poul Sørensen
A paper in Nature reports that mRNA vaccines targeting SARS-CoV-2, COVID-19, also sensitize tumours to immune checkpoint inhibitors. #medsky 🧪
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade - Nature
mRNA vaccines targeting SARS-CoV-2 also sensitize tumours to immune checkpoint inhibitors.
go.nature.com
October 29, 2025 at 1:50 AM
A paper in Nature reports that mRNA vaccines targeting SARS-CoV-2, COVID-19, also sensitize tumours to immune checkpoint inhibitors. #medsky 🧪
Conversion of pathogenic T cells into functionally stabilized Treg cells for antigen-specific immunosuppression in pemphigus vulgaris www.science.org/doi/10.1126/...
Conversion of pathogenic T cells into functionally stabilized Treg cells for antigen-specific immunosuppression in pemphigus vulgaris
Functionally stable regulatory T cells converted in vitro from pathogenic T cells can confer antigen-specific immunosuppression in pemphigus vulgaris.
www.science.org
November 3, 2025 at 8:08 AM
Conversion of pathogenic T cells into functionally stabilized Treg cells for antigen-specific immunosuppression in pemphigus vulgaris www.science.org/doi/10.1126/...
Reposted by Poul Sørensen
Big news today! 🎉
#MJFF #RNAtherapeutics #Parkinsondisease #RNAsplicingmodulation #Pseudoexon #Innovation
#MJFF #RNAtherapeutics #Parkinsondisease #RNAsplicingmodulation #Pseudoexon #Innovation
#invernatherapeutics #mjff #grant #parkinsonsdisease #lrrk2 #biotech #startup #neuroscience #innovation | Inverna Therapeutics
🎉 Exciting news from Inverna Therapeutics! 🚀
We’re honored to announce that Inverna has been awarded a grant from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) as part of the LRRK2 Inv...
www.linkedin.com
October 9, 2025 at 7:56 AM
Big news today! 🎉
#MJFF #RNAtherapeutics #Parkinsondisease #RNAsplicingmodulation #Pseudoexon #Innovation
#MJFF #RNAtherapeutics #Parkinsondisease #RNAsplicingmodulation #Pseudoexon #Innovation
Extremely well deserved !
#immunetolerance
#immunetolerance
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"
Stay tuned for more.
#NobelPrize
Stay tuned for more.
#NobelPrize
October 6, 2025 at 2:08 PM
Extremely well deserved !
#immunetolerance
#immunetolerance
Reposted by Poul Sørensen
Huntington's Breakthrough May Not Be The Success It Seems, Expert Cautions #Science #HealthandMedicine #Neurology #HuntingtonsDisease #MedicalResearch
Huntington's Breakthrough May Not Be The Success It Seems, Expert Cautions
Time will tell.
purescience.news
September 30, 2025 at 7:30 AM
Huntington's Breakthrough May Not Be The Success It Seems, Expert Cautions #Science #HealthandMedicine #Neurology #HuntingtonsDisease #MedicalResearch
Nice to see the RNA splicing modulation area developing - keep an eye on @invernatx.com and their more precise and rationally designed oligonucleotide based approach
Skyhawk inks another deal, this time with Merck KGaA in a pact estimated to be worth more than $2B.
Skyhawk's RNA mission gets another $2B lift via Merck KGaA
Merck KGaA became its ninth pharma company passenger through an RNA-targeting small molecule collaboration with Skyhawk Therapeutics.
endpoints.news
August 19, 2025 at 3:16 PM
Nice to see the RNA splicing modulation area developing - keep an eye on @invernatx.com and their more precise and rationally designed oligonucleotide based approach
Reposted by Poul Sørensen
Nature: Cancelling mRNA studies is the highest irresponsibility
go.nature.com/3HDx4wD
cc Jay Bhattacharya
go.nature.com/3HDx4wD
cc Jay Bhattacharya
August 15, 2025 at 8:21 PM
Nature: Cancelling mRNA studies is the highest irresponsibility
go.nature.com/3HDx4wD
cc Jay Bhattacharya
go.nature.com/3HDx4wD
cc Jay Bhattacharya
Reposted by Poul Sørensen
Changes in the gut that lead to an immune “scar” could be the cause of ongoing celiac disease symptoms www.nature.com/articles/s41...
www.nature.com
May 17, 2025 at 3:25 PM
Changes in the gut that lead to an immune “scar” could be the cause of ongoing celiac disease symptoms www.nature.com/articles/s41...
Reposted by Poul Sørensen
What a night, what a performance from this far from 100% team, one of the great European nights at the Emirates.
Declan Rice has produced two of the greatest free kicks you'll ever see at this level, and we 100% deserved that third goal too.
Incredible. This team deserves so much love. #arsenal
Declan Rice has produced two of the greatest free kicks you'll ever see at this level, and we 100% deserved that third goal too.
Incredible. This team deserves so much love. #arsenal
April 8, 2025 at 8:57 PM
What a night, what a performance from this far from 100% team, one of the great European nights at the Emirates.
Declan Rice has produced two of the greatest free kicks you'll ever see at this level, and we 100% deserved that third goal too.
Incredible. This team deserves so much love. #arsenal
Declan Rice has produced two of the greatest free kicks you'll ever see at this level, and we 100% deserved that third goal too.
Incredible. This team deserves so much love. #arsenal
Reposted by Poul Sørensen
So grateful to share a bit of my experience with @maddow.msnbc.com last night. Thanks so much for having me.
www.msnbc.com/rachel-maddo...
www.msnbc.com/rachel-maddo...
'This is shameful': Trump sows animosity and mistrust abroad, degrading Americans in the process
Rufus Gifford, former U.S. ambassador to Denmark, talks with Rachel Maddow about the animosity and mistrust Donald Trump is sowing among even allied nations, and the shock of betrayal people around th...
www.msnbc.com
March 29, 2025 at 5:46 PM
So grateful to share a bit of my experience with @maddow.msnbc.com last night. Thanks so much for having me.
www.msnbc.com/rachel-maddo...
www.msnbc.com/rachel-maddo...
Reposted by Poul Sørensen
Myelin antigen-specific effector CD8+ T cells induce chronic CNS autoimmunity in a CD4+ T cell-dependent manner. https://www.biorxiv.org/content/10.1101/2025.03.25.645315v1
March 29, 2025 at 12:15 PM
Myelin antigen-specific effector CD8+ T cells induce chronic CNS autoimmunity in a CD4+ T cell-dependent manner. https://www.biorxiv.org/content/10.1101/2025.03.25.645315v1
Reposted by Poul Sørensen
Denmark hits back at ‘tone’ of US vice-president’s criticism over Greenland
Denmark hits back at ‘tone’ of US vice-president’s criticism over Greenland
‘This is not how you talk to your close allies,’ says Danish foreign minister Lars Løkke Rasmussen
Denmark has hit back against JD Vance’s comments that Copenhagen has not done enough for Greenland.
The US vice-president made his remark on Friday during a trip to the Pituffik space base in north-western Greenland, viewed by both Copenhagen and Nuuk as a provocation. Continue reading...
www.theguardian.com
March 29, 2025 at 12:19 PM
Denmark hits back at ‘tone’ of US vice-president’s criticism over Greenland
Indeed bad news for we beer and cheese lovers - better for wine aficionados...
Look at the table if you wish to become a healthy old man/woman/….
It’s from today’s Nature Medicine by A.-J. Tessier et al. Optimal dietary patterns for healthy aging.
Hopefully somebody will soon publish conflicting results proving that beer is not that bad, after all.
It’s from today’s Nature Medicine by A.-J. Tessier et al. Optimal dietary patterns for healthy aging.
Hopefully somebody will soon publish conflicting results proving that beer is not that bad, after all.
March 29, 2025 at 11:56 AM
Indeed bad news for we beer and cheese lovers - better for wine aficionados...
Great pitching Inverna and our novel RNA splicing modulation platform at the BIO Europe Spring Startup Spotlight competition ! www.linkedin.com/posts/mads-a...
#RNAtherapeutics #Splicingmodulation #pseudoexon #innovation @invernatx.com
#RNAtherapeutics #Splicingmodulation #pseudoexon #innovation @invernatx.com
#bioeuropespring #rnasplicingmodulation #pseudoexons | Mads Aaboe Jensen, MSc, PhD
Poul Sørensen, CEO, is presenting Inverna’s platform for RNA splicing modulation at BIO-Europe Spring 2025 in Milan.
#BioEuropeSpring #RNASplicingModulation…
www.linkedin.com
March 19, 2025 at 9:53 AM
Great pitching Inverna and our novel RNA splicing modulation platform at the BIO Europe Spring Startup Spotlight competition ! www.linkedin.com/posts/mads-a...
#RNAtherapeutics #Splicingmodulation #pseudoexon #innovation @invernatx.com
#RNAtherapeutics #Splicingmodulation #pseudoexon #innovation @invernatx.com
Exciting times for Allero Therapeutics !
www.linkedin.com/posts/allero...
#immunotherapy #innovation #inversevaccine
www.linkedin.com/posts/allero...
#immunotherapy #innovation #inversevaccine
Allero Therapeutics BV on LinkedIn: Sanofi iDEA-iTECH Awards - Europe
We are very excited to share that Allero is a winner of the prestigious Sanofi IDEA-TECH Awards 2024! We are very much looking forward to the year of…
www.linkedin.com
February 18, 2025 at 4:17 PM
Exciting times for Allero Therapeutics !
www.linkedin.com/posts/allero...
#immunotherapy #innovation #inversevaccine
www.linkedin.com/posts/allero...
#immunotherapy #innovation #inversevaccine
Reposted by Poul Sørensen
A new generation of cancer-preventing vaccines could wipe out tumors before they form.
Learn more on #WorldCancerDay: https://scim.ag/4gk8Qmo
Learn more on #WorldCancerDay: https://scim.ag/4gk8Qmo
February 4, 2025 at 7:56 PM
A new generation of cancer-preventing vaccines could wipe out tumors before they form.
Learn more on #WorldCancerDay: https://scim.ag/4gk8Qmo
Learn more on #WorldCancerDay: https://scim.ag/4gk8Qmo
Reposted by Poul Sørensen
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses
www.nature.com/articles/s41...
@natimmunol.bsky.social
www.nature.com/articles/s41...
@natimmunol.bsky.social
January 13, 2025 at 6:13 PM
Differential roles of human CD4+ and CD8+ regulatory T cells in controlling self-reactive immune responses
www.nature.com/articles/s41...
@natimmunol.bsky.social
www.nature.com/articles/s41...
@natimmunol.bsky.social
Reposted by Poul Sørensen
Simulating 500 million years of evolution with a language model
"An AI model developed to design proteins simulates 500 million years of protein evolution in developing new fluorescent protein"
www.science.org/doi/10.1126/...
"An AI model developed to design proteins simulates 500 million years of protein evolution in developing new fluorescent protein"
www.science.org/doi/10.1126/...
January 17, 2025 at 10:23 AM
Simulating 500 million years of evolution with a language model
"An AI model developed to design proteins simulates 500 million years of protein evolution in developing new fluorescent protein"
www.science.org/doi/10.1126/...
"An AI model developed to design proteins simulates 500 million years of protein evolution in developing new fluorescent protein"
www.science.org/doi/10.1126/...
#JPM is a wrap - what a week it was ! www.linkedin.com/posts/poulso...
Poul Sørensen on LinkedIn: #jpm25
Reflecting on #JPM25 - what a productive and energizing week in SF connecting with old and new friends!
Exciting to introduce Argobio Studio and Inverna…
www.linkedin.com
January 18, 2025 at 8:18 AM
#JPM is a wrap - what a week it was ! www.linkedin.com/posts/poulso...
It’s #JPM time in SF ! Looking forward to a productive week and discussing partnerships on Inverna Therapeutics, our next generation RNA splicing modulation platform
#JPM25 #JPM2025 #rnatherapeutics @invernatx.com @argobiostudio.com
#JPM25 #JPM2025 #rnatherapeutics @invernatx.com @argobiostudio.com
January 12, 2025 at 3:58 PM
It’s #JPM time in SF ! Looking forward to a productive week and discussing partnerships on Inverna Therapeutics, our next generation RNA splicing modulation platform
#JPM25 #JPM2025 #rnatherapeutics @invernatx.com @argobiostudio.com
#JPM25 #JPM2025 #rnatherapeutics @invernatx.com @argobiostudio.com