@thedavidpeck.bsky.social
Pinned
Reposted
First human #H5N1 case of 2026 in #Cambodia: a 30-year-old man from Kampot province. Sequencing, virus isolation & animal investigations ongoing. Dead chicken at home before onset. Patient has since recovered. 🦠💉😷🐓🥼🔬🧪
Sequencing, contact tracing, and poultry investigations ongoing.
Sequencing, contact tracing, and poultry investigations ongoing.
February 14, 2026 at 1:42 PM
«4) Conclusions: Humans have strong immunity to the N1 component of H5N1 but not to the N5 component of H5N5. Also, H5N1 strains with additional glycosylation sites in N1 partially escape immunity. H5N5 and H5N1+glyc would have it likely easier to spread in humans.»
x.com/florian_kram...
#H5N1
x.com/florian_kram...
#H5N1
February 13, 2026 at 6:26 AM
«4) Conclusions: Humans have strong immunity to the N1 component of H5N1 but not to the N5 component of H5N5. Also, H5N1 strains with additional glycosylation sites in N1 partially escape immunity. H5N5 and H5N1+glyc would have it likely easier to spread in humans.»
x.com/florian_kram...
#H5N1
x.com/florian_kram...
#H5N1
«1) We have a new preprint paper out about population immunity to H5N1 and H5N5. Results are in line with what others have seen but there are two new findings.
2) Since there was a recent fatal H5N5 infection in the US, we also assessed population immunity to N5
x.com/florian_kram...
#H5N1 #h5n5
2) Since there was a recent fatal H5N5 infection in the US, we also assessed population immunity to N5
x.com/florian_kram...
#H5N1 #h5n5
February 13, 2026 at 6:24 AM
«1) We have a new preprint paper out about population immunity to H5N1 and H5N5. Results are in line with what others have seen but there are two new findings.
2) Since there was a recent fatal H5N5 infection in the US, we also assessed population immunity to N5
x.com/florian_kram...
#H5N1 #h5n5
2) Since there was a recent fatal H5N5 infection in the US, we also assessed population immunity to N5
x.com/florian_kram...
#H5N1 #h5n5
Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase
antibodies
«we determined that human sera contain widespread, functional antibodies targeting H5N1 neuraminidase, which correlate with virus neutralization…»
www.medrxiv.org/content/10.6...
#H5N1
antibodies
«we determined that human sera contain widespread, functional antibodies targeting H5N1 neuraminidase, which correlate with virus neutralization…»
www.medrxiv.org/content/10.6...
#H5N1
February 13, 2026 at 6:14 AM
Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase
antibodies
«we determined that human sera contain widespread, functional antibodies targeting H5N1 neuraminidase, which correlate with virus neutralization…»
www.medrxiv.org/content/10.6...
#H5N1
antibodies
«we determined that human sera contain widespread, functional antibodies targeting H5N1 neuraminidase, which correlate with virus neutralization…»
www.medrxiv.org/content/10.6...
#H5N1
Reposted
Immunity: Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed indviduals
Katharina Daniel et al
bit.ly/4krTqjy
@cp-immunity.bsky.social
Katharina Daniel et al
bit.ly/4krTqjy
@cp-immunity.bsky.social
February 12, 2026 at 3:09 AM
Immunity: Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed indviduals
Katharina Daniel et al
bit.ly/4krTqjy
@cp-immunity.bsky.social
Katharina Daniel et al
bit.ly/4krTqjy
@cp-immunity.bsky.social
«During our long-term IAV serological surveillance study, HPAI outbreaks caused by the H5N1 clade 2.3.4.4.b had been reported during active and passive surveillance campaigns in Spain»
doi.org/10.1111/zph....
doi.org/10.1111/zph....
February 11, 2026 at 5:02 PM
«During our long-term IAV serological surveillance study, HPAI outbreaks caused by the H5N1 clade 2.3.4.4.b had been reported during active and passive surveillance campaigns in Spain»
doi.org/10.1111/zph....
doi.org/10.1111/zph....
Reposted
Vaccination against H5 HP avian influenza virus leads to persistent immune response in wild king penguins
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Vaccination against H5 HP avian influenza virus leads to persistent immune response in wild king penguins - Nature Communications
High pathogenicity avian influenza (HPAI) may endanger not only domestic poultry but also wild birds. Here authors show that upon immunisation of king penguin chicks with a self-amplifying mRNA vaccin...
www.nature.com
February 9, 2026 at 2:00 PM
Vaccination against H5 HP avian influenza virus leads to persistent immune response in wild king penguins
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted
Hot News from @naturehealthglobal.bsky.social Re. the documentary Blame: Nominated for major award, released in theaters in Germany/Switzerland, & US PREMIERE at the Sedona Film Festival in April 2026!!! 🧵
naturehealthglobal.org/update-blame...
naturehealthglobal.org/update-blame...
UPDATE! Blame Movie: Awards, Theatrical Release, US Premiere! - Nature.Health.Global
“Blame” is a documentary movie by the Oscar-nominated, Sundance Festival award winning Swiss Director Christian Frei. The film focuses on three scientists,
naturehealthglobal.org
February 7, 2026 at 3:11 PM
Hot News from @naturehealthglobal.bsky.social Re. the documentary Blame: Nominated for major award, released in theaters in Germany/Switzerland, & US PREMIERE at the Sedona Film Festival in April 2026!!! 🧵
naturehealthglobal.org/update-blame...
naturehealthglobal.org/update-blame...
Reposted
According to below report, avian influenza H5N1 diagnosed in association with mortality of nearly 10,000 crows (species?) in Darbhanga, Bihar, north-east India since January 2026.
H5N1 avian influenza confirmed in Darbhanga, Bihar, after thousands of crows found dead in Ward 31 area.
Lab tests from Bhopal verified the outbreak as authorities deploy veterinary teams across the district to inspect poultry farms and prevent spread.
Lab tests from Bhopal verified the outbreak as authorities deploy veterinary teams across the district to inspect poultry farms and prevent spread.
February 6, 2026 at 12:26 PM
According to below report, avian influenza H5N1 diagnosed in association with mortality of nearly 10,000 crows (species?) in Darbhanga, Bihar, north-east India since January 2026.
«We outlined here the current epidemiology, unique pathophysiology of the disease in the setting of pregnancy, suggested clinical approach during pregnancy and birth, and suggested future directions regarding vaccine research and policy approaches…»
www.mdpi.com/1999-4915/18...
#h5n1
www.mdpi.com/1999-4915/18...
#h5n1
February 6, 2026 at 10:29 AM
«We outlined here the current epidemiology, unique pathophysiology of the disease in the setting of pregnancy, suggested clinical approach during pregnancy and birth, and suggested future directions regarding vaccine research and policy approaches…»
www.mdpi.com/1999-4915/18...
#h5n1
www.mdpi.com/1999-4915/18...
#h5n1
Reposted
Our 2 H5N1 research projects are making great progress
Progress: baselines for farm air sampling, new testing platform, ⬆️ wastewater tracking for early detection, new genomic surveillance tools & more https://www.bccdc.ca/resource-gallery/Documents/Avian_flu_How_can_I_protect_myself.pdf
Progress: baselines for farm air sampling, new testing platform, ⬆️ wastewater tracking for early detection, new genomic surveillance tools & more https://www.bccdc.ca/resource-gallery/Documents/Avian_flu_How_can_I_protect_myself.pdf
February 5, 2026 at 10:00 PM
Our 2 H5N1 research projects are making great progress
Progress: baselines for farm air sampling, new testing platform, ⬆️ wastewater tracking for early detection, new genomic surveillance tools & more https://www.bccdc.ca/resource-gallery/Documents/Avian_flu_How_can_I_protect_myself.pdf
Progress: baselines for farm air sampling, new testing platform, ⬆️ wastewater tracking for early detection, new genomic surveillance tools & more https://www.bccdc.ca/resource-gallery/Documents/Avian_flu_How_can_I_protect_myself.pdf
““We diagnosed high pathogenicity avian influenza as the cause of death for nearly all of the dead skuas we found at Beak Island,” said first author Matteo Iervolino, a Ph.D. candidate at Erasmus MC in Rotterdam, The Netherlands.»
www.ucdavis.edu/health/news/...
#H5N1
www.ucdavis.edu/health/news/...
#H5N1
February 5, 2026 at 3:57 PM
““We diagnosed high pathogenicity avian influenza as the cause of death for nearly all of the dead skuas we found at Beak Island,” said first author Matteo Iervolino, a Ph.D. candidate at Erasmus MC in Rotterdam, The Netherlands.»
www.ucdavis.edu/health/news/...
#H5N1
www.ucdavis.edu/health/news/...
#H5N1
Phase 1 and preclinical studies reveal safety, pharmacokinetics, and efficacy of intranasal delivery of the influenza antibody CR9114
pubmed.ncbi.nlm.nih.gov/41637527/
#H5N1
pubmed.ncbi.nlm.nih.gov/41637527/
#H5N1
February 5, 2026 at 3:52 PM
Phase 1 and preclinical studies reveal safety, pharmacokinetics, and efficacy of intranasal delivery of the influenza antibody CR9114
pubmed.ncbi.nlm.nih.gov/41637527/
#H5N1
pubmed.ncbi.nlm.nih.gov/41637527/
#H5N1
1) Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases.
➡️ Spotify:
open.spotify.com/show/2LxUpjumK…
➡️ Apple Podcasts:
podcasts.apple.com/at/podcast/vir���
https://virological.podigee.io
➡️ Spotify:
open.spotify.com/show/2LxUpjumK…
➡️ Apple Podcasts:
podcasts.apple.com/at/podcast/vir���
https://virological.podigee.io
Spotify – Web Player
https://open.spotify.com/show/2LxUpjumK…
February 5, 2026 at 9:45 AM
1) Episode 0 of my new podcast viroLOGICAL is online. This first episode is a little longer and gives a general overview of viruses and viral diseases.
➡️ Spotify:
open.spotify.com/show/2LxUpjumK…
➡️ Apple Podcasts:
podcasts.apple.com/at/podcast/vir���
https://virological.podigee.io
➡️ Spotify:
open.spotify.com/show/2LxUpjumK…
➡️ Apple Podcasts:
podcasts.apple.com/at/podcast/vir���
https://virological.podigee.io
«The viral titers in the patient's lungs and pharynx decreased rapidly after oseltamivir treatment, yet it still fatal. »
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…»
doi.org/10.1016/j.jm...
#h5n6
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…»
doi.org/10.1016/j.jm...
#h5n6
February 4, 2026 at 8:12 AM
«The viral titers in the patient's lungs and pharynx decreased rapidly after oseltamivir treatment, yet it still fatal. »
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…»
doi.org/10.1016/j.jm...
#h5n6
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…»
doi.org/10.1016/j.jm...
#h5n6
«The viral titers in the patient's lungs and pharynx decreased rapidly after oseltamivir treatment, yet it still fatal. »
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…”
doi.org/10.1016/j.jm...
#h5n6
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…”
doi.org/10.1016/j.jm...
#h5n6
Redirecting
doi.org
February 4, 2026 at 8:12 AM
«The viral titers in the patient's lungs and pharynx decreased rapidly after oseltamivir treatment, yet it still fatal. »
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…”
doi.org/10.1016/j.jm...
#h5n6
A case of Avian Influenza A (H5N6) presented with secondary infection in Anhui Province, China, 2024
«Mutations in S133A and T156S showed…”
doi.org/10.1016/j.jm...
#h5n6
Reposted
I won’t stop reporting the truth. The First Amendment is the bedrock of our democracy, and I’ll continue to fight to protect it 🤝🏾🇺🇸
January 31, 2026 at 4:40 AM
I won’t stop reporting the truth. The First Amendment is the bedrock of our democracy, and I’ll continue to fight to protect it 🤝🏾🇺🇸
Reposted
The team behind a nasal COVID-19 vaccine is now targeting bird flu. With H5N1 spreading to farms and, in rare cases, people, WashU Medicine's infectious disease experts developed a nasal spray that protects animals from infection. medicine.washu.edu/news/nasal-v...
Nasal vaccine combats bird flu infection in rodents | WashU Medicine
WashU Medicine researchers have developed and tested a mucosal vaccine against the highly pathogenic H5N1 avian influenza virus.
medicine.washu.edu
January 30, 2026 at 8:51 PM
The team behind a nasal COVID-19 vaccine is now targeting bird flu. With H5N1 spreading to farms and, in rare cases, people, WashU Medicine's infectious disease experts developed a nasal spray that protects animals from infection. medicine.washu.edu/news/nasal-v...
Reposted
Influenza A virus H5-naive individuals possess low but detectable H5-neutralizing IgG antibodies against A/Texas/37/2024 that can cross-neutralize H1 and protect mice from lethal H5N1 infection @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
January 30, 2026 at 8:59 PM
Influenza A virus H5-naive individuals possess low but detectable H5-neutralizing IgG antibodies against A/Texas/37/2024 that can cross-neutralize H1 and protect mice from lethal H5N1 infection @cp-immunity.bsky.social
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted
An intranasal adenoviral-vectored vaccine protects against highly pathogenic avian influenza H5N1 in naive and antigen-experienced animals
www.cell.com/cell-reports...
@cp-cellrepmed.bsky.social @washumedicine.bsky.social
www.cell.com/cell-reports...
@cp-cellrepmed.bsky.social @washumedicine.bsky.social
January 30, 2026 at 9:14 PM
An intranasal adenoviral-vectored vaccine protects against highly pathogenic avian influenza H5N1 in naive and antigen-experienced animals
www.cell.com/cell-reports...
@cp-cellrepmed.bsky.social @washumedicine.bsky.social
www.cell.com/cell-reports...
@cp-cellrepmed.bsky.social @washumedicine.bsky.social
Webby, et al: Retail Milk Monitoring of Influenza A(H5N1) in Dairy Cattle, United States, 2024–2025
«Our study revealed that early in the outbreak, the influenza A(H5N1) virus was more widespread than reported….»
wwwnc.cdc.gov/eid/article/...
doi.org/10.3201/eid3...
#H5N1
«Our study revealed that early in the outbreak, the influenza A(H5N1) virus was more widespread than reported….»
wwwnc.cdc.gov/eid/article/...
doi.org/10.3201/eid3...
#H5N1
January 30, 2026 at 8:13 PM
Webby, et al: Retail Milk Monitoring of Influenza A(H5N1) in Dairy Cattle, United States, 2024–2025
«Our study revealed that early in the outbreak, the influenza A(H5N1) virus was more widespread than reported….»
wwwnc.cdc.gov/eid/article/...
doi.org/10.3201/eid3...
#H5N1
«Our study revealed that early in the outbreak, the influenza A(H5N1) virus was more widespread than reported….»
wwwnc.cdc.gov/eid/article/...
doi.org/10.3201/eid3...
#H5N1
Reposted
More extensive testing reveals antibodies to highly pathogenic avian influenza in five cows (earlier testing: only one cow) on a dairy farm in the Netherlands. www.omropfryslan.nl/nl/nieuws/18...
Vijf koeien met antistoffen tegen vogelgriep in Noardeast-Fryslân
Dat vertelde demissionair minister Wiersma vanavond aan de Tweede Kamer in een debat over zoönosen en dierenziekten.
www.omropfryslan.nl
January 29, 2026 at 10:54 PM
More extensive testing reveals antibodies to highly pathogenic avian influenza in five cows (earlier testing: only one cow) on a dairy farm in the Netherlands. www.omropfryslan.nl/nl/nieuws/18...
Reposted
Out Now! Genomic features associated with sustained mammalian transmission of avian influenza A viruses #MicroSky
Genomic features associated with sustained mammalian transmission of avian influenza A viruses
Nature Microbiology, Published online: 27 January 2026; doi:10.1038/s41564-025-02257-4Reduced GC-related content in the influenza A virus genome may be a necessary condition for sustained mammalian transmission and should be included in risk assessment tools for pandemic influenza.
go.nature.com
January 28, 2026 at 5:31 AM
Out Now! Genomic features associated with sustained mammalian transmission of avian influenza A viruses #MicroSky
Reposted
Communications Earth & Environment : An outbreak of highly pathogenic avian influenza H5N1 could impact the dairy cattle sector and the broader economy in the United States
Guillaume Morel et al
go.nature.com/4k0CgcB
Guillaume Morel et al
go.nature.com/4k0CgcB
January 27, 2026 at 6:20 PM
Communications Earth & Environment : An outbreak of highly pathogenic avian influenza H5N1 could impact the dairy cattle sector and the broader economy in the United States
Guillaume Morel et al
go.nature.com/4k0CgcB
Guillaume Morel et al
go.nature.com/4k0CgcB
Reposted
Communications Biology: Oseltamivir and baloxavir monotherapy and combination therapy efficacy against clade 2.3.4.4b A(H5N1) influenza virus infection in ferrets
Jessica A. Belser et al
go.nature.com/46bI6SI
Jessica A. Belser et al
go.nature.com/46bI6SI
January 26, 2026 at 3:12 PM
Communications Biology: Oseltamivir and baloxavir monotherapy and combination therapy efficacy against clade 2.3.4.4b A(H5N1) influenza virus infection in ferrets
Jessica A. Belser et al
go.nature.com/46bI6SI
Jessica A. Belser et al
go.nature.com/46bI6SI