Bhavesh Parmar
thatmassspecguy.bsky.social
Bhavesh Parmar
@thatmassspecguy.bsky.social
High-throughput proteomics and low-throughput SM-banter.
Amazing start to @hupo-org.bsky.social world congress #HUPO2025 in snowy Toronto. I will be at poster 39 later today for those curious about translation/degradation proteomics in the context of ubiquitin E3s and supervised machine learning. See you there!! #teamMassSpec
November 10, 2025 at 4:44 PM
Looking forward to an exciting time at @hupo-org.bsky.social world congress in Toronto! swing by my poster on Monday to know more about dynamic proteomic screen of E3 ligases. #HUPO2025 #teamMassSpec #proteomics
November 7, 2025 at 7:53 AM
Reposted by Bhavesh Parmar
I'm a huge fan of this proposal!

If we can get vendor buy-in to an open, common format, it could bring more computational folks into the field. How can these folks be excited about #proteomics when its hard to even read the already complicated data?

pubs.acs.org/doi/10.1021/...
mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format
Advances in mass spectrometry (MS) instrumentation, including higher resolution, faster scan speeds, and improved sensitivity, have dramatically increased the data volume and complexity. The adoption of imaging and ion mobility further amplifies these challenges in proteomics, metabolomics, and lipidomics. Current open formats such as mzML and imzML struggle to keep pace due to large file sizes, slow data access, and limited metadata support. Vendor-specific formats offer faster access but lack interoperability and long-term archival guarantees. We here lay the groundwork for mzPeak, a next-generation community data format designed to address these challenges and support high-throughput, multidimensional MS workflows. By adopting a hybrid model that combines efficient binary storage for numerical data and both human- and machine-readable metadata storage, mzPeak will reduce file sizes, accelerate data access, and offer a scalable, adaptable solution for evolving MS technologies. For researchers, mzPeak will support complex workflows and regulatory compliance through faster access, improved metadata, and interoperability. For vendors, it offers a streamlined, open alternative to proprietary formats. mzPeak aims to become a cornerstone of MS data management, enabling sustainable, high-performance solutions for future data types and fostering collaboration across the mass spectrometry community.
pubs.acs.org
October 10, 2025 at 5:53 PM
Reposted by Bhavesh Parmar
My lab is looking for an enthusiastic postdoc who is motivated to grow with our team and passionate about research on cellular resilience. If you are interested, or know someone who might be, please apply through the link below.
Postdoctoral Research Fellow (f/m/d)
Postdoc: Investigate the role of translational regulation in controlling cell resilience,sequencing- and mass spectrometry,independently analyze the resulting data
www.mpi-hlr.de
October 6, 2025 at 12:59 PM
Gearing up for what promises to be an exciting week ahead @crg.eu #CRGtraining #teamMassSpec
October 6, 2025 at 7:38 AM
Reposted by Bhavesh Parmar
The location and food will make it impossible for anyone else to ever make a better EUPA conference. Thank you for organising such an excellent event! #EUPA2025
June 19, 2025 at 11:24 AM
How often do you get to talk at a conference with views like this? Had an amazing time sharing my research at #eupa2025.
June 18, 2025 at 11:45 AM
Gearing up for #EuPA2025 next week & super excited to share my work on combining siRNA screen with translation/degradation proteomics. I mean, look at that auditorium!! 😮 Want to know how you can do high-throughput proteomics without a liquid handling robot or a high speed TOF like its 2020? join me
June 10, 2025 at 12:52 PM
Reposted by Bhavesh Parmar
Very excited for Fast & Fair peer review - authors get decisions, with reviews, within 7 business days of submission. Reviews are high quality - lots of quality control by our academic editors, plus we pay reviewers.
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days. #fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick @danielgorelick.bsky.social at: bit.ly/4kYD1mL
March 25, 2025 at 11:25 AM
Reposted by Bhavesh Parmar
The analogy of omics data normalization and cooking:
some processing is usually necessary, overcooking makes it bland, highly over-processed foods are unhealthy, and the quality of the ingredients matters.
February 27, 2025 at 8:01 AM
What is up with @novonordisk.bsky.social ? 📉
February 15, 2025 at 3:18 PM
Hey #TeamMassSpec, with all the super duper ultra fast TOF based DIA methods out there, how are you managing the throughput & depth on your old tribrids, QEs and Exploris? Any TMT aficionados out here getting 30spd, for instance, or even 15 with >8k proteins?
January 6, 2025 at 5:50 PM
Happy holidays, and a reminder to ALWAYS check your synthesised peptide standards for isotope purity. #teammassspec
December 24, 2024 at 9:48 PM
#TeamMassSpec represent at the first symposium on advances in therapeutic approaches.
Wrapped up our first Symposium on Advances in Therapeutic Approaches! 🎉 Huge thanks to all the inspiring speakers and extra kudos to our very own @thatmassspecguy.bsky.social for unveiling our innovative #proteomics methods to profile E3 ligase & #PROTAC targets. 🔬✨
#TheraNova, #ENABLE, #Proxidrugs
December 9, 2024 at 7:16 AM
Forgot to introduce myself on here so here you go. Hello #teammassspec, I’m a 3rd year postdoc with 13 years of experience doing proteomics at all career stages (MSc, technical scientist, JRF, PhD). India>Australia>Belgium>Germany. Here’s me a couple of weeks ago at #HUPO Dresden
November 17, 2024 at 4:16 PM
actively muting/hiding posts & people in an attempt to curate my algorithm better this time around. #godspeed
November 14, 2024 at 1:05 PM