Andrea Telatin
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telatin.bsky.social
Andrea Telatin
@telatin.bsky.social
530 followers 340 following 31 posts
Head of bioinformatics at the Quadram Institute - https://github.com/telatin/
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telatin.bsky.social
How well do current tools detect antimicrobial resistance genes in metagenomes?

@sumeet-tiwari.bsky.social & team benchmarked 5 widely used methods across different sequencing coverages and community complexities, highlighting trade-offs between accuracy and computational cost.
February 6, 2026 at 10:46 PM
Reposted by Andrea Telatin
peaseroland.bsky.social
More on the UKRI/STFC funding squeeze.
Significant quote: “It is clear that no UK university will want to open lecturer positions in curiosity-driven research if such lecturers would not be able to attract much national funding." KCL's Lucien Heurtier.

www.theguardian.com/science/2026...
UK ‘could lose generation of scientists’ with cuts to projects and research facilities
UK’s research funding body says best scientists are taking posts overseas due to lack of job stability at home
www.theguardian.com
February 6, 2026 at 5:39 PM
Reposted by Andrea Telatin
samuelhorsfield.bsky.social
Super excited to announce the release of gene and intergenic region annotation from the largest bacterial genome and MAG datasets available, including AllTheBacteria, GTDB, SPIRE, HRGM, mOTUs and MGnify - dereplicated and available from HuggingFace huggingface.co/AllTheBacteria
Hugging Face – The AI community building the future.
We’re on a journey to advance and democratize artificial intelligence through open source and open science.
huggingface.co
February 5, 2026 at 1:27 PM
telatin.bsky.social
Information, gone. 👋
Washington Post lays off hundreds of staff after BEZOS wastes 75 MILLIONS on Melanias flop documentary
February 5, 2026 at 1:18 PM
Reposted by Andrea Telatin
jcsmoot.bsky.social
Important study highlighting the need for rigorous quality control during sequencing and the value of analyzing sequence read depth variation in assemblies.
February 5, 2026 at 3:06 AM
Reposted by Andrea Telatin
jcamthrash.bsky.social
Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning www.nature.com/articles/s41... #jcampubs
Accurate plasmid reconstruction from metagenomics data using assembly–alignment graphs and contrastive learning - Nature Biotechnology
PlasMAAG uses cross-sample information to improve plasmid reconstruction from metagenomic samples.
www.nature.com
February 4, 2026 at 8:20 PM
Reposted by Andrea Telatin
seqera.io
💻 Join us next week for Nextflow Training Week (Feb 9-13) - free online training for those new to @nextflow.io or looking to reinforce the basics.

👉 Register here: hubs.la/Q041v13y0
February 3, 2026 at 10:01 AM
Reposted by Andrea Telatin
seqfu.bsky.social
Meet seqfu less

youtu.be/e77tXBM6fRs?...
SeqFu dev - preview of `seqfu less` [coming with 1.24.0]
YouTube video by Andrea Telatin
youtu.be
February 1, 2026 at 5:50 PM
Reposted by Andrea Telatin
quadraminstitute.bsky.social
🆕 Vacancy! We are looking for a Senior Research Scientist to support with day-to-day running of @dfigeys.bsky.social lab, including line management of staff, overseeing budgets, and leading the scientific direction.

💷 £45,450 to £56,750
🗓️ Apply by 15 February 2026
➡️ buff.ly/UpcuEPa
A social card with the text, "Senior Research Scientist Microbiome Assay and Metaproteomics, to support with day-to-day running of the Figeys lab, including line management, overseeing budgets and scientific direction. Salary: £45,450 to £56,750, Contract length: 2 years, Apply by 15 February 2026."
January 7, 2026 at 2:30 PM
Reposted by Andrea Telatin
ammarabdalrahem.bsky.social
1/🧵
Major milestone unlocked for mycology! 🍄

We just published a massive genomic resource in 𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐟𝐢𝐜 𝐃𝐚𝐭𝐚, releasing 2,695 complete circular mitochondrial species assembled from public data

This single dataset nearly 𝐓𝐑𝐈𝐏𝐋𝐄𝐒 📈the known mitochondrial diversity of the Kingdom Fungi
rdcu.be/eYZ2h
January 15, 2026 at 2:31 PM
Reposted by Andrea Telatin
donmoyn.bsky.social
Some important new government policy that Native Americans might be interested in:
paleofuture.bsky.social Matt Novak @paleofuture.bsky.social · 28d
Trump talks about Denmark and Greenland just now: "The fact that they landed a boat there 500 years ago doesn't mean that they own the land."
January 9, 2026 at 10:02 PM
Reposted by Andrea Telatin
natmicrobiol.nature.com
#Resource

HRGM2 - a catalogue of 155,211 high-quality metagenome-assembled genomes spanning 41 countries that allows improved genome-scale metabolic modelling and functional characterization of human gut microbes.

#MicroSky #MicrobiomeSky 🦠💻

www.nature.com/articles/s41...
A human gut metagenome-assembled genome catalogue spanning 41 countries supports genome-scale metabolic models - Nature Microbiology
HRGM2 is a catalogue of 155,211 high-quality metagenome-assembled genomes spanning 41 countries that allows improved genome-scale metabolic modelling and functional characterization of human gut micro...
www.nature.com
December 4, 2025 at 3:27 PM
Reposted by Andrea Telatin
albertvilella.bsky.social
@mrclmb.bsky.social alumnus Tony Hyman to become new @embl.org director general
November 29, 2025 at 6:06 AM
Reposted by Andrea Telatin
biorxiv-bioinfo.bsky.social
Optimized k-mer search across millions of bacterial genomes on laptops https://www.biorxiv.org/content/10.1101/2025.11.23.690050v1
November 26, 2025 at 4:47 PM
telatin.bsky.social
Ring validations are important. @quadraminstitute.bsky.social took part of this study from dna to analysis
November 16, 2025 at 1:35 PM
Reposted by Andrea Telatin
hansonmark.bsky.social
We wrote the Strain on scientific publishing to highlight the problems of time & trust. With a fantastic group of co-authors, we present The Drain of Scientific Publishing:

a 🧵 1/n

Drain: arxiv.org/abs/2511.04820
Strain: direct.mit.edu/qss/article/...
Oligopoly: direct.mit.edu/qss/article/...
A table showing profit margins of major publishers. A snippet of text related to this table is below. 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year. A figure detailing the drain on researcher time. 1. The four-fold drain 1.2 Time The number of papers published each year is growing faster than the scientific workforce, with the number of papers per researcher almost doubling between 1996 and 2022 (Figure 1A). This reflects the fact that publishers’ commercial desire to publish (sell) more material has aligned well with the competitive prestige culture in which publications help secure jobs, grants, promotions, and awards. To the extent that this growth is driven by a pressure for profit, rather than scholarly imperatives, it distorts the way researchers spend their time. The publishing system depends on unpaid reviewer labour, estimated to be over 130 million unpaid hours annually in 2020 alone (9). Researchers have complained about the demands of peer-review for decades, but the scale of the problem is now worse, with editors reporting widespread difficulties recruiting reviewers. The growth in publications involves not only the authors’ time, but that of academic editors and reviewers who are dealing with so many review demands. Even more seriously, the imperative to produce ever more articles reshapes the nature of scientific inquiry. Evidence across multiple fields shows that more papers result in ‘ossification’, not new ideas (10). It may seem paradoxical that more papers can slow progress until one considers how it affects researchers’ time. While rewards remain tied to volume, prestige, and impact of publications, researchers will be nudged away from riskier, local, interdisciplinary, and long-term work. The result is a treadmill of constant activity with limited progress whereas core scholarly practices – such as reading, reflecting and engaging with others’ contributions – is de-prioritized. What looks like productivity often masks intellectual exhaustion built on a demoralizing, narrowing scientific vision. A table of profit margins across industries. The section of text related to this table is below: 1. The four-fold drain 1.1 Money Currently, academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it. The dominant four are Elsevier, Springer Nature, Wiley and Taylor & Francis, which collectively generated over US$7.1 billion in revenue from journal publishing in 2024 alone, and over US$12 billion in profits between 2019 and 2024 (Table 1A). Their profit margins have always been over 30% in the last five years, and for the largest publisher (Elsevier) always over 37%. Against many comparators, across many sectors, scientific publishing is one of the most consistently profitable industries (Table S1). These financial arrangements make a substantial difference to science budgets. In 2024, 46% of Elsevier revenues and 53% of Taylor & Francis revenues were generated in North America, meaning that North American researchers were charged over US$2.27 billion by just two for-profit publishers. The Canadian research councils and the US National Science Foundation were allocated US$9.3 billion in that year. The costs of inaction are plain: wasted public funds, lost researcher time, compromised scientific integrity and eroded public trust. Today, the system rewards commercial publishers first, and science second. Without bold action from the funders we risk continuing to pour resources into a system that prioritizes profit over the advancement of scientific knowledge.
November 11, 2025 at 11:52 AM
Reposted by Andrea Telatin
jburnmurdoch.ft.com
Quick thread on the BBC and the political and societal significance of recent developments:

One of the main reasons the UK has historically been so much less polarised than the US, is that Britain has a shared source of information, consumed and trusted by most people regardless of their politics.
November 10, 2025 at 1:43 PM
Reposted by Andrea Telatin
brianvan.bsky.social
So it turns out... the US air travel system was incredibly, deeply dependent on federal funding to just run day-to-day all this time, to the benefit of private airline shareholders, when everyone thinks that state-run trains are leeching off the government. Weird!
November 9, 2025 at 12:10 AM
Reposted by Andrea Telatin
quadraminstitute.bsky.social
⏰ Closing soon! We’re looking for a Research Scientist (Bioinformatics) to join the Laboratory of Dr Kai Cheng in our Food, Microbiome and Health programme

💷 £37,500 to £41,500
🗓️ Apply by 9 November 2025
➡️ buff.ly/DqLnYek
A social card with a digital illustration of of AI and the text "Research Scientist (Bioinformatics) to develop and apply computational methods for metaproteomics and multi-omics to advance precision microbiome research. Salary : £37,500 to £41,500, Contract length: 2 years, Apply by 9 November 2025"
November 1, 2025 at 3:30 PM
Reposted by Andrea Telatin
clementsui.bsky.social
Escherichia coli with a 57-codon genetic code | Science www.science.org/doi/10.1126/...
Escherichia coli with a 57-codon genetic code
The near-universal genetic code uses 64 codons to encode the 20 canonical amino acids and protein synthesis. Here, we designed and generated Escherichia coli with a 4-megabase synthetic genome in whic...
www.science.org
October 26, 2025 at 1:18 AM
Reposted by Andrea Telatin
stephenturner.us
U.S. Biotech Future Is Now Made in China www.realclearworld.com/articles/202...
U.S. Biotech Future Is Now Made in China
This past year, oncologists across the United States faced an agonizing choice: Which cancer patients would receive their full, life-saving chemotherapy regimen and which would face delays or substand
www.realclearworld.com
October 15, 2025 at 3:55 PM
Reposted by Andrea Telatin
stephenturner.us
From genotype to phenotype with 1,086 near telomere-to-telomere yeast genomes www.nature.com/articles/s41... 🧬🖥️🧪 github.com/HaploTeam/10...
October 15, 2025 at 5:55 PM
Reposted by Andrea Telatin
erinyoung.bsky.social
"WGS-informed prevention could hypothetically generate net savings of €1.35 million annually if transmission was stopped once a clonal isolate was detected in a second patient."

I think that translates to ~1.5 million US dollars
Estimating the potential economic and health impact of integrated genomic surveillance in a hospital setting
Integrated genomic surveillance, combining whole genome sequencing (WGS) of bacterial isolates with patient movement data, promises improved detection…
www.sciencedirect.com
October 14, 2025 at 9:04 PM
Reposted by Andrea Telatin
drgdavidson.bsky.social
🚨🔊 Fully funded PhD!! 🚨🔊

Are you interested in wildlife gut microbiomes? Love birds, fieldwork and bioinformatics? Want to join a collaborative and supportive team? Looking for training to become an independent scientist?

Please apply!

Informal enquiries welcome!

www.uea.ac.uk/course/phd-d...
October 10, 2025 at 10:16 AM
Reposted by Andrea Telatin
bioinf.bsky.social
Interested in modelling metabolism from food -> gut microbiome -> blood ? 5 days left to apply for a fully funded position to investigate this. 👇👇👇
bioinf.bsky.social Falk Hildebrand @bioinf.bsky.social · Sep 13
We want to explore the metabolic interactions among gut bacteria, when the human host eats different foods - maybe this explain partly the Enterosignature structure?
Please do apply for our bioinformatic post to explore this question in metagenomes: jobs.quadram.ac.uk/Details.asp?...
September 25, 2025 at 8:31 AM