sungw.bsky.social
@sungw.bsky.social
Reposted
限制性内切酶发现者、1978年诺贝尔生理学奖获得者哈密尔顿.史密斯在圣地亚哥家中去世,享年94岁。10月25日就去世了,现在在报道出来。没有限制性内切酶的发现,也就没有遗传工程。他在伯克利获得数学学位后,去霍普金斯改学医,妻子是他当住院医时认识的护士,之后改做科研研究微生物学,限制性内切酶是他在霍普金斯当教授的第二年发现的。从霍普金斯退休后到克雷格·文特尔研究所继续做科研,近80岁时领导制造第一个人造细胞。
December 7, 2025 at 2:49 AM
4 spiders a day. That's too much cuteness
November 29, 2025 at 1:08 PM
My new pet
November 28, 2025 at 10:59 PM
Reposted
I got a plasmid map from another lab as *.dna file 🧪. The SnapGene program can open it. I do not want to install their "free" viewer in my linux system. The solution: OpenCloning opencloning.org . With it, I loaded the .dna file and downloaded the sequence plus a nice map. Thanks OpenCloning team 🤩
OpenCloning
An Open-Source web application for DNA engineering
opencloning.org
November 27, 2025 at 7:53 PM
Reposted
New findings reveal UCP1-independent thermogenesis via ATP-consuming metabolism of monomethyl branched-chain fatty acids in peroxisomes. Energy balance redefined! PMID:40963015, Nature 2025, @Nature https://doi.org/10.1038/s41586-025-09517-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Peroxisomal metabolism of branched fatty acids regulates energy homeostasis | Nature
Brown and beige adipocytes express uncoupling protein 1 (UCP1), a mitochondrial protein that dissociates respiration from ATP synthesis and promotes heat production and energy expenditure. However, UCP1−/− mice are not obese1–5, consistent with the existence of alternative mechanisms of thermogenesis6–8. Here we describe a UCP1-independent mechanism of thermogenesis involving ATP-consuming metabolism of monomethyl branched-chain fatty acids (mmBCFA) in peroxisomes. These fatty acids are synthesized by fatty acid synthase using precursors derived from catabolism of branched-chain amino acids9 and our results indicate that β-oxidation of mmBCFAs is mediated by the peroxisomal protein acyl-CoA oxidase 2 (ACOX2). Notably, cold exposure upregulated proteins involved in both biosynthesis and β-oxidation of mmBCFA in thermogenic fat. Acute thermogenic stimuli promoted translocation of fatty acid synthase to peroxisomes. Brown-adipose-tissue-specific fatty acid synthase knockout decreased cold
doi.org
November 15, 2025 at 10:00 PM
Beautiful Cuckoo Wasp.
November 10, 2025 at 12:25 PM
Reposted
🧪Science has saved many lives!

Synthetic nitrogen fertilizer: Estimated 2.3 billion lives saved
Blood groups/storage leading to blood transfusions: 1.1 billion
High yield wheat: 245 million
Penicillin: 203M
Insulin: 200M
Chlorinated water: 177M
ourworldindata.org/data-insight...
September 26, 2025 at 9:48 PM
Pancorius thorelli. A cute jumping spider with a heart shaped patch on its head.
May 3, 2025 at 3:07 AM
Bioluminescent mushroom Mycena chlorophos.
May 3, 2025 at 1:28 AM
Enada rosea nymph
April 9, 2025 at 1:55 AM
Yellow-spotted Stink Bug (黃斑黑蝽 Erthesina fullo) NJ CN.
April 8, 2025 at 11:58 PM
Double stinky Anada rosea
February 25, 2025 at 1:59 PM
Jacaranda obtusifolia. Planted at a garden.
February 24, 2025 at 12:35 AM
Stink bug
February 20, 2025 at 12:19 AM
Leptocentrus sp.
February 6, 2025 at 12:37 AM
Dead end. A Malayan mistletoe seed hits on hand rail.
January 31, 2025 at 12:17 AM
Anada rosea. The green form can changes to red.
January 28, 2025 at 10:35 PM
Assassin bug (Physoderes curculionis)
January 17, 2025 at 12:12 PM
Laglaise's Garden Spider
January 11, 2025 at 11:04 PM
Stalk-eyed fly (Megalabops quadriguttata)
November 30, 2024 at 12:24 AM
Colourful caterpillar of day flying moth (Cyclosia macularia)
November 24, 2024 at 12:47 AM
Reposted
Fake - AI generated.
The real Helix nebula is amassing as it is.
November 21, 2024 at 9:25 AM
Reposted
Keel-billed Toucan at @tapirvalley.bsky.social

#birds #toucans 🌿
November 19, 2024 at 4:13 AM
Reposted
WOW 🤩 my photograph got over 70k likes. Tysm! 🥹
November 16, 2024 at 5:51 PM
Reposted
Sri Lanka tried RFK Jr.'s food plan, and it was catastrophic. Productivity plummeted, causing food shortages, skyrocketing prices, lost exports, and an economic collapse. Farmers faced huge losses, forcing the government to reverse the ban and import costly emergency food.
In Sri Lanka, Organic Farming Went Catastrophically Wrong
A nationwide experiment is abandoned after producing only misery.
foreignpolicy.com
November 15, 2024 at 6:50 AM