Sunandan Mukherjee
sunandan.bsky.social
Sunandan Mukherjee
@sunandan.bsky.social
Computational structural biologist ¦ RNA ¦ Post doc @IIMCB
Reposted by Sunandan Mukherjee
Exciting news for the RNA research community!

The Human RNome Project has been launched: a global effort to map all human RNAs and their chemical modifications. Proud to support it and contribute to the article in Genome Biology doi.org/10.1186/s130...
#RNA #bioinformatics #RNAstructure #modomics
Unlocking the regulatory code of RNA: launching the Human RNome Project - Genome Biology
The human RNome, the complete set of RNA molecules in human cells, arises through complex processing and includes diverse molecular species. While research traditionally focuses on four canonical nucl...
genomebiology.biomedcentral.com
October 25, 2025 at 10:27 PM
Reposted by Sunandan Mukherjee
"...research isn’t just about data and discoveries; it’s about people, perspectives, and the places that inspire us."
@sunandan.bsky.social from @iimcb.bsky.social has written about his experience of visiting Edinburgh and #IGC for a two-week research visit 👉
Science, Stories and Stone: My Research Journey in Edinburgh – Institute of Genetics and Cancer
A blog for our community to write about their interests and to share their stories.
edin.ac
October 17, 2025 at 9:45 AM
In our new review, we dive into the latest breakthroughs in modeling RNA and RNA–protein complexes: from deep learning and molecular simulations to hybrid AI–physics methods and even quantum approaches. 🧬

👉 Open access: www.sciencedirect.com/science/arti...

#RNA #MolecularModeling #AI
doi.org
August 16, 2025 at 5:10 PM
The most comprehensive testament of the current trends of RNA structural biology:
doi.org/10.1038/s415...
Knowing when to fold ’em - Nature Methods
A steadily growing toolbox of techniques is helping researchers to understand the structural complexity that enables RNA molecules to perform a dizzying array of functions in the cell.
doi.org
June 17, 2025 at 12:45 PM
Reposted by Sunandan Mukherjee
Proud to be part of this interdisciplinary work with @sebastianglatt.bsky.social, Ting-Yu Lin, our teams at @MCB_UJ & @IIMCB_Warsaw, and collaborators from France! #cryoEM + #biophysics + #modeling reveal how #pseudouridine shapes human tRNA structure and stability. 🧬 #RNAmodifications
tRNAs are small and sport heterogeneous base modifications – yet @sebastianglatt.bsky.social @jmbujnicki.bsky.social Ting-Yu Lin 林亭妤 et al show #cryoEM combined with biophysical & computational approaches can give insights into how #pseudouridine affects human tRNA!
www.embopress.org/doi/full/10....
April 29, 2025 at 9:04 PM
Delighted to be a part of this wonderful collaborative work!
#tRNA #PSU #cryoEM
tRNAs are small and sport heterogeneous base modifications – yet @sebastianglatt.bsky.social @jmbujnicki.bsky.social Ting-Yu Lin 林亭妤 et al show #cryoEM combined with biophysical & computational approaches can give insights into how #pseudouridine affects human tRNA!
www.embopress.org/doi/full/10....
April 30, 2025 at 12:05 AM
May this festive season bring you good health, success, and countless blessings. 🌟 Take time to reflect and find peace in the little moments. Here’s to joy, love, and togetherness!

Merry Christmas and Happy holidays! ❤️✨

#FestiveSeason #GoodHealth #Blessings
December 25, 2024 at 1:21 PM
Reposted by Sunandan Mukherjee
ChimeraX 1.9 has been released! Session view can now be automatically saved and restored. New ​'Find Cavities' tool identifying pockets in models. www.rbvi.ucsf.edu/chimerax/dow...
Download UCSF ChimeraX
www.rbvi.ucsf.edu
December 14, 2024 at 9:08 AM
Sounds promising!
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science.

www.biorxiv.org/content/10.1...
December 6, 2024 at 6:11 PM
We are not yet there to predict the large #RNA molecules unless the non-canonical contacts are detected more accurately!
#CASP16
Conclusions from RNA section at #CASP16, without a template all fail. All small targets had a template.
December 3, 2024 at 5:23 PM
RNA-Puzzles Round V paper is out:
www.nature.com/articles/s41...
It reports the evaluation of blind prediction of 23 targets predicted by 18 groups worldwide. I'm glad that our group ranked as one of the top four groups in this competition!

#RNA #prediction #RNApuzzles #CASP16
RNA-Puzzles Round V: blind predictions of 23 RNA structures - Nature Methods
The results of the Fifth RNA-Puzzles contest highlights advances in RNA three-dimensional structure prediction and uncovers new insights into RNA folding and structure.
www.nature.com
December 2, 2024 at 7:45 PM
Excited to share our recently published review on #RNA structure prediction and modeling tools! 🧬 We reported advances using both theoretical approaches and experimental data. Free access available until Nov 13, 2024!👇

👉 authors.elsevier.com/a/1jpyq3SNvcAc…#RNAN#StructuralBiologyg#Modelingng
https://authors.elsevier.com/a/1jpyq3SNvcAc…
September 25, 2024 at 9:33 AM
Happy to share that I had the opportunity to present our method, #SimRNA_Cry, for modeling RNA structures using #CryoEM data at the Computational Approach to RNA Structure and Function conference in #Benasque, Spain!

PC: Nithin C and Eugene Baulin
July 30, 2024 at 9:29 AM
Happy to share our new publication on the discovery of the first ever genuine knot in a natural RNA molecules.
Full article: doi.org/10.1016/j.jm...
Redirecting
doi.org
February 10, 2024 at 7:21 AM
Demise of Ustad Rashid Khan is a great loss for Indian Classical Music! May his soul rest in peace!
January 9, 2024 at 4:22 PM