Ujwal Punyamurtula
sumukha.bsky.social
Ujwal Punyamurtula
@sumukha.bsky.social
PhD Student @UTAustin
Reposted by Ujwal Punyamurtula
In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide.

news.harvard.edu/gazette/stor...
NIH funding delivers exponential economic returns — Harvard Gazette
Report finds all 50 states reap gains in patient health, job creation, research resources, business development.
news.harvard.edu
March 12, 2025 at 11:49 PM
wait til this guy learns what proteins can do
February 27, 2025 at 5:43 AM
Reposted by Ujwal Punyamurtula
We might have a few less seats in Congress but we’re not going to be the minority. We’re going to be the opposition.

Thanks @leximcmenamin.bsky.social & @teenvogue.com for covering.

www.teenvogue.com/story/maxwel...
"Resist, Obstruct, Protect Our People": Maxwell Frost Has a Plan for Taking on Trump
"Why is a single Democrat voting to confirm any of these Trump Cabinet nominees?"
www.teenvogue.com
February 7, 2025 at 9:13 PM
Reposted by Ujwal Punyamurtula
"Stop the Coup!"

Scene at Treasury.
February 4, 2025 at 9:46 PM
Reposted by Ujwal Punyamurtula
I don't do politics here and i won't start now. But before i get back to obscure embryology from 17th century Tibet (yep, that's coming soon), I want to say this: NOTHING is ending this week. Only beginning. Bloviating and panicking won't help. So everyone please, calm down and get to work.
January 28, 2025 at 10:00 PM
well put!

Before protein mass spec when we were trying to purify peptides by chromatography, I used to joke that it was too bad that all the peaks did not come with name tags.

It turns out they did, their masses. We just needed to learn how to read them.

/fin
January 27, 2025 at 6:32 AM
Reposted by Ujwal Punyamurtula
I have and will continue to. But you know why I say it here ? Because @bsky.app is 30m strong and growing quickly. The collective wisdom and influence of users here is far greater than any individual democrat.

I can't say it enough. Bluesky can be the influence that can counter RW media.
No offense, Mark, but you have influence and power most of us don’t. Why don’t you speak up to those in DC you have connections with? Actions speak louder than words as you well know.
January 22, 2025 at 9:25 PM
the importance of doing proteomics! it’s the ground truth of what’s going on
5,562 proteins were found to have tissue-specific enrichment across 32 human tissues.

◼️ The majority of them (3,088) are enriched at the protein but not RNA level.

🧠 The brain hosts the largest number of proteins that are only enriched at the protein level but not RNA level.
January 22, 2025 at 6:56 PM
I’m inclined to believe this will bring more publicity/attention to proteomics, which is a good thing IMO.
Bad news for the quant-types in proteomics. While I doubt that the study will find anything of lasting value, they will find a enough stuff that is statistically significant to make a lot of noise.
www.ukbiobank.ac.uk/learn-more-a...
Launch of world’s most significant protein study set to usher in new understanding for medicine
www.ukbiobank.ac.uk
January 12, 2025 at 5:57 AM
Can’t say enough about how good the ending of wind and truth was. stormlight is officially my fav book series of all time
January 3, 2025 at 12:50 AM
Reposted by Ujwal Punyamurtula
I think I follow lab topics more than specific papers, and easily my top (def top 3) thing [still] going on in 2024 in proteomics land is @edwardmarcotte.bsky.social et al.

pubmed.ncbi.nlm.nih.gov/38853926/

www.biorxiv.org/content/10.1...
Ancient eukaryotic protein interactions illuminate modern genetic traits and disorders - PubMed
All eukaryotes share a common ancestor from roughly 1.5 - 1.8 billion years ago, a single-celled, swimming microbe known as LECA, the Last Eukaryotic Common Ancestor. Nearly half of the genes in moder...
pubmed.ncbi.nlm.nih.gov
December 29, 2024 at 2:13 PM
All I’m going to say is that everything would be better off with Medicare4All in this country
December 5, 2024 at 7:26 PM
this might be my favorite review for a game i’ve never played (yet)
Metaphor is my game of the year. i asked director Hashino a very specific question.

He replied, “To be honest, you asked a question that really hits the core. I’ve done many interviews, and I haven’t had a question like this.”

www.washingtonpost.com/entertainmen...
Review | The year’s smartest game asks: Is civil democracy just a fantasy?
“Metaphor: ReFantazio” is the most audacious, exciting video game story of the year as it chronicles the birth of democracy.
www.washingtonpost.com
November 23, 2024 at 5:12 AM
interesting perspectives in this thread - my take is that we need to improve quantitative rigor in proteomics while also preserving the valuable biological insights listomics provides
Having worked in a CRO for the past 20 months where accurate quant is everything. Proteomics is slowly moving this way, but the days of listomics are over. Getting accurate quant on proteins of genuine interest is the future. Don’t see many Internal standards being used either.
November 18, 2024 at 6:44 AM