Dan Kliebenstein
@spicybotrytis.bsky.social
Dogs, Horses and Gardening, with a side of research on complexity and metabolic warfare in plants
If you at the cloning of QTLs since the early 90s, we have always known structural variants were important for phenotypic variation. The pangenomes are confirmation rather than origination of the idea.
February 6, 2026 at 2:54 PM
If you at the cloning of QTLs since the early 90s, we have always known structural variants were important for phenotypic variation. The pangenomes are confirmation rather than origination of the idea.
In the age of internet searching, etc. What is the point of a ScienCV or any biosketch for a grant proposal?
January 29, 2026 at 10:01 PM
In the age of internet searching, etc. What is the point of a ScienCV or any biosketch for a grant proposal?
Reposted by Dan Kliebenstein
Question for the #PlantPathology community. What is your favorite work showing how a pathogen detects the plant and responds? e.g. does Pseudomonas sense host/non-host and adjust?, Xanthamonas?, Blumeria?, etc?. Trying to build up a literature base independent of google.
January 27, 2026 at 9:45 PM
Question for the #PlantPathology community. What is your favorite work showing how a pathogen detects the plant and responds? e.g. does Pseudomonas sense host/non-host and adjust?, Xanthamonas?, Blumeria?, etc?. Trying to build up a literature base independent of google.
Reposted by Dan Kliebenstein
🌱From Trends in Plant Science: Evolution-informed pest management pinpoints PUB21 as a key switch for citrus HLB resistance, with AI-designed peptides boosting immunity and killing the pathogen. (Daniel J. Kliebenstein)
▶️ www.cell.com/trends/plant...
#PlantScience #PlantPathology
▶️ www.cell.com/trends/plant...
#PlantScience #PlantPathology
Fighting citrus Huanglongbing with evolutionary principles
Conventional pest management often accelerates the evolution of resistance in pests,
resulting in an unsustainable cycle of control. By contrast, evolution-informed pest
management (EIPM) can outmaneu...
www.cell.com
January 26, 2026 at 5:42 PM
🌱From Trends in Plant Science: Evolution-informed pest management pinpoints PUB21 as a key switch for citrus HLB resistance, with AI-designed peptides boosting immunity and killing the pathogen. (Daniel J. Kliebenstein)
▶️ www.cell.com/trends/plant...
#PlantScience #PlantPathology
▶️ www.cell.com/trends/plant...
#PlantScience #PlantPathology
Question for the #PlantPathology community. What is your favorite work showing how a pathogen detects the plant and responds? e.g. does Pseudomonas sense host/non-host and adjust?, Xanthamonas?, Blumeria?, etc?. Trying to build up a literature base independent of google.
January 27, 2026 at 9:45 PM
Question for the #PlantPathology community. What is your favorite work showing how a pathogen detects the plant and responds? e.g. does Pseudomonas sense host/non-host and adjust?, Xanthamonas?, Blumeria?, etc?. Trying to build up a literature base independent of google.
Reposted by Dan Kliebenstein
New paper with @smishra677.bsky.social!
How many different trees can be generated by just one duplication event? It turns out A WHOLE LOT, if you consider the coalescent process.
1/
www.biorxiv.org/content/10.6...
How many different trees can be generated by just one duplication event? It turns out A WHOLE LOT, if you consider the coalescent process.
1/
www.biorxiv.org/content/10.6...
www.biorxiv.org
January 23, 2026 at 11:10 AM
New paper with @smishra677.bsky.social!
How many different trees can be generated by just one duplication event? It turns out A WHOLE LOT, if you consider the coalescent process.
1/
www.biorxiv.org/content/10.6...
How many different trees can be generated by just one duplication event? It turns out A WHOLE LOT, if you consider the coalescent process.
1/
www.biorxiv.org/content/10.6...
One last Christmas puppy evening!
January 18, 2026 at 3:21 AM
One last Christmas puppy evening!
The brothers are finally together albeit with a bit of fog.
January 18, 2026 at 3:20 AM
The brothers are finally together albeit with a bit of fog.
Reposted by Dan Kliebenstein
Predicting epistasis across proteins by structural logic by the amazing Michelle Tang et al
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
January 16, 2026 at 5:34 PM
Predicting epistasis across proteins by structural logic by the amazing Michelle Tang et al
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Ever wondered if diverse plant species respond similarly when infected by the same exact pathogen? Infect different asterids and rosids with the same Botrytis genotypes and teh short answer, quite differently.
www.biorxiv.org/content/10.6...
@annajomu.bsky.social @ccaseys.bsky.social
(1/3)
www.biorxiv.org/content/10.6...
@annajomu.bsky.social @ccaseys.bsky.social
(1/3)
A multi-plant transcriptomic atlas reveals conserved and lineage specific defense architectures in response to Botrytis cinerea
Generalist pathogens pose a challenge to plant immunity by infecting diverse hosts while harboring extensive intraspecific genetic variation. Whether evolutionary distant plant lineages rely on a shar...
www.biorxiv.org
January 15, 2026 at 10:52 PM
Ever wondered if diverse plant species respond similarly when infected by the same exact pathogen? Infect different asterids and rosids with the same Botrytis genotypes and teh short answer, quite differently.
www.biorxiv.org/content/10.6...
@annajomu.bsky.social @ccaseys.bsky.social
(1/3)
www.biorxiv.org/content/10.6...
@annajomu.bsky.social @ccaseys.bsky.social
(1/3)
The combined ideas of shifting to a fixed monetary supply via crypto and increasing population seems to have nothing to do with abating inflation. Instead it is a giant hedge to shift all inflation costs onto the havenots and the next generation. And fix wealth in few hands forever.
January 9, 2026 at 11:11 PM
The combined ideas of shifting to a fixed monetary supply via crypto and increasing population seems to have nothing to do with abating inflation. Instead it is a giant hedge to shift all inflation costs onto the havenots and the next generation. And fix wealth in few hands forever.
How much do you think pathogens "measure" their host to plan their attack? Do they simply say "likely host, attack." and then hope it works. Or do they say "Host X, attack with chess Plan X".
And if they "measure" how do they "measure"?
And if they "measure" how do they "measure"?
January 8, 2026 at 10:31 PM
How much do you think pathogens "measure" their host to plan their attack? Do they simply say "likely host, attack." and then hope it works. Or do they say "Host X, attack with chess Plan X".
And if they "measure" how do they "measure"?
And if they "measure" how do they "measure"?
Reposted by Dan Kliebenstein
Bruce Hammock was a scientific legend, brilliant and kind. He was always happy to talk and collaborate without ego. Like many others, I will miss him. 💔
Bruce Hammock: 1947-2026
UC Davis Distinguished Professor Bruce Hammock at his desk, Feb. 24, 2009.
entnem.ucdavis.edu
January 8, 2026 at 6:40 AM
Bruce Hammock was a scientific legend, brilliant and kind. He was always happy to talk and collaborate without ego. Like many others, I will miss him. 💔
On NLR evolution, any thoughts about a potential for something equivalent to the MHC locus in plants? A meta-stable syntenic position across the viridiplantae that constantly spits out such completely new NLRs that we haven't realized it exists because no NLR orthology?
January 6, 2026 at 11:03 PM
On NLR evolution, any thoughts about a potential for something equivalent to the MHC locus in plants? A meta-stable syntenic position across the viridiplantae that constantly spits out such completely new NLRs that we haven't realized it exists because no NLR orthology?
An interesting and rarely juxtaposed dichotomy of theories/assumptions/thoughts(?) on plant specialized metabolites.
1) specialized metabolites are costly to produce and at loggerheads with growth.
2) specialized metabolites are largely discarded and not catabolized/recycled.
Thoughts?
#secmet
1) specialized metabolites are costly to produce and at loggerheads with growth.
2) specialized metabolites are largely discarded and not catabolized/recycled.
Thoughts?
#secmet
January 6, 2026 at 11:02 PM
An interesting and rarely juxtaposed dichotomy of theories/assumptions/thoughts(?) on plant specialized metabolites.
1) specialized metabolites are costly to produce and at loggerheads with growth.
2) specialized metabolites are largely discarded and not catabolized/recycled.
Thoughts?
#secmet
1) specialized metabolites are costly to produce and at loggerheads with growth.
2) specialized metabolites are largely discarded and not catabolized/recycled.
Thoughts?
#secmet
Someone wants their Christmas peppermint.
December 25, 2025 at 8:21 PM
Someone wants their Christmas peppermint.
Reposted by Dan Kliebenstein
The CYP71A, NIT, AMI, and IAMH gene families are dispensable for indole-3-acetaldoxime-mediated auxin biosynthesis in Arabidopsis (Mario Fenech, Javier Brumos, Aleš Pěnčík, Brianne Edwards, et al) doi.org/10.1093/plce... #PlantScience @aspbofficial
The CYP71A, NIT, AMI, and IAMH gene families are dispensable for indole-3-acetaldoxime-mediated auxin biosynthesis in Arabidopsis
Research challenges previously postulated genetic pathways for the conversion of indole-3-acetaldoxime into indole-3-acetic acid in the auxin-overproducing
doi.org
December 23, 2025 at 4:55 PM
Reposted by Dan Kliebenstein
Convergence and constraint in glucosinolate evolution across the Brassicaceae (Amanda Agosto Ramos, Kevin A Bird, Annanya Jain, Gabriel Philip Sumo, Odinaka Okegbe, Lucy Holland, Daniel J Kliebenstein) doi.org/10.1093/plce... #PlantScience @aspbofficial
Convergence and constraint in glucosinolate evolution across the Brassicaceae
Studying a glucosinolate enzyme across the Brassicaceae shows evolution of plant specialized metabolism involves independent gene losses, distal duplicatio
doi.org
December 23, 2025 at 4:54 PM
Reposted by Dan Kliebenstein
Bummed to see corn plants drawn so clearly wrong. The tassel does not magically turn into an ear on the top of the plant. Not a great look for a plant journal.
#TansleyReview: Mycelial dynamics in arbuscular mycorrhizal #fungi
Vasilis Kokkoris 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
Vasilis Kokkoris 👇
📖 nph.onlinelibrary.wiley.com/doi/10.1111/...
#LatestIssue #PlantScience
December 21, 2025 at 3:59 PM
Bummed to see corn plants drawn so clearly wrong. The tassel does not magically turn into an ear on the top of the plant. Not a great look for a plant journal.
Interesting how I keep seeing papers say that QTL mapping of enzyme variation to metabolite to insect herbivory and tritrophic interactions hasn't been done before.
#secmet
#secmet
December 19, 2025 at 6:04 PM
Interesting how I keep seeing papers say that QTL mapping of enzyme variation to metabolite to insect herbivory and tritrophic interactions hasn't been done before.
#secmet
#secmet
What if generalist pathogens aren't brute killers but poly-specialist perfectionists, optimizing to each host.
December 18, 2025 at 11:19 PM
What if generalist pathogens aren't brute killers but poly-specialist perfectionists, optimizing to each host.
Settled for a long winters nap.
December 18, 2025 at 1:47 AM
Settled for a long winters nap.
What are everyone's favorite papers showing that individual plant TFs function to coordinate primary and specialized metabolism? Rather than solely regulating a specialized metabolite.
#secmet
#secmet
December 17, 2025 at 10:19 PM
What are everyone's favorite papers showing that individual plant TFs function to coordinate primary and specialized metabolism? Rather than solely regulating a specialized metabolite.
#secmet
#secmet
An atmospheric holidays.
December 17, 2025 at 5:02 AM
An atmospheric holidays.
Reposted by Dan Kliebenstein
Every time a scientist says "my area of expertise takes years of training but I can learn the rest from a book" a chatGPT agent gets its wings.
Every single gd time.
Every single gd time.
a man in a suit and tie is standing in the rain .
ALT: a man in a suit and tie is standing in the rain .
media.tenor.com
December 12, 2025 at 12:57 AM
Every time a scientist says "my area of expertise takes years of training but I can learn the rest from a book" a chatGPT agent gets its wings.
Every single gd time.
Every single gd time.