Simon Pfisterer
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spfisterer.bsky.social
Simon Pfisterer
@spfisterer.bsky.social
Science and technology shape the world. Hope I can help along the path with my research group www.pfistererlab.org and as a founder of www.moncytehealth.com a novel precision medicine company.
Pinned
Extremely happy that our work got accepted in #ATVB! We functionally profiled 400 biobank samples, linking cellular lipid uptake, storage and handling to treatment outcomes of statin therapy and residual cardiovascular risk.

www.ahajournals.org/doi/10.1161/...
Back from #AHA2025 scientific sessions! Two poster presentations and discussing the future of cardiovascular disease prevention with colleagues and partners. @ahajournals.bsky.social @eassociety.bsky.social
#cholesterol, #CVDprevention.
November 13, 2025 at 6:27 AM
Reposted by Simon Pfisterer
Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex | Science www.science.org/doi/10.1126/...
Adipogenin promotes the development of lipid droplets by binding a dodecameric seipin complex
The microprotein adipogenin (Adig) is predominantly expressed in adipose tissues. Here, we found that Adig interacts with seipin to form a stable, rigid complex. We present the structure of the seipin...
www.science.org
November 10, 2025 at 10:41 AM
It is a great honour to be part of this study! Congratulations to Daniel Tabet, @fritzroth.bsky.social and the entire team!! This is a huge step forward regarding functional studies of LDLR!

www.science.org/doi/10.1126/...

@helsinki.fi @eassociety.bsky.social
The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR
Variants in the familial hypercholesterolemia gene LDLR—the most important genetic driver of cardiovascular disease—can raise circulating low-density lipoprotein (LDL) cholesterol concentrations and i...
www.science.org
October 31, 2025 at 9:27 AM
Reposted by Simon Pfisterer
Proud to share a preprint of our paper on how bridge-like lipid transport protein VPS13C senses lysosomal membrane tension in anticipation of membrane lesions to initiate net ER-to-lysosome lipid transfer for efficient lysosomal repair www.biorxiv.org/content/10.1...
VPS13C/PARK23 initiates lipid transfer and membrane remodeling for efficient lysosomal repair
Perturbations in lysosome integrity are tightly linked to neurological disorders and ageing, but the underlying pathogenic mechanisms are incompletely understood. Using an unbiased proteomic approach,...
www.biorxiv.org
October 25, 2025 at 1:11 PM
At MONCYTE Health we are looking for a laboratory technician. Are you ready to join a vibrant and exciting team, pushing boundaries in precision medicine? Please apply!

More information can be found here:
moncytehealth.com/open-positio...

The closing date for applications is: 30.11.2025
Open position: on-site laboratory technician - MONCYTE Health
Job description Company Description MONCYTE Health, established in 2024, is an early-stage Finnish health technology company developing a novel solution that integrates cellular diagnostics with robot...
moncytehealth.com
October 20, 2025 at 7:01 AM
Reposted by Simon Pfisterer
We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
October 17, 2025 at 2:56 PM
Reposted by Simon Pfisterer
🚨🚨🚨 We are launching the 2nd application round for the Erasmus Mundus Joint Master’s Program MemBioMed, offering cutting-edge training on exploring the complex behavior of cellular membranes & unlocking their therapeutic potential. Students can apply here: life.univ-cotedazur.eu/internationa...
October 17, 2025 at 3:18 PM
Reposted by Simon Pfisterer
The EU High-Level Event on cardiovascular health is happening right now at the European Parliament 🇪🇺. Patients, policymakers & experts are coming together to highlight why early screening for FH and Lp(a) must become a European priority.
September 25, 2025 at 3:06 PM
Cycling to work refreshes my brain and improves cardiovascular health! It is also super beautiful if you work in #Helsinki

@eassociety.bsky.social #cholesterol #cvd
September 18, 2025 at 10:06 AM
The European Lipoprotein Club Meeting #ELC is special! Great to be back, meeting friends and discussing our latest data from www.moncytehealth.com! @eassociety.bsky.social @barteltlab.bsky.social
September 11, 2025 at 8:37 AM
Reposted by Simon Pfisterer
Come and work with us 5-year position available for a University Researcher in Bioimaging 1.11.2025-31.12.2030

abo.rekrytointi.com/paikat/index...
University Researcher in Bioimaging / Universitetsforskare med inriktning bioimaging, 1.11.2025-31.12.2030
abo.rekrytointi.com
September 10, 2025 at 11:28 AM
Reposted by Simon Pfisterer
Join us for a special session in recognition of Familial Hypercholesterolaemia (FH) Awareness Week. This webinar features the recorded session from EAS 2025 in Glasgow, highlighting key insights into FH diagnosis, treatment, and global strategies.

Register here: eas.to/WebSep24Reg
September 9, 2025 at 6:36 PM
Reposted by Simon Pfisterer
We (with @nicolasdray.bsky.social @zenlabpasteur.bsky.social) are happy to release officially FishFeats, our #napari plugin to streamline 3D smFish/RNA quantification! 🎊
Available here: github.com/gletort/Fish... user documentation: gletort.github.io/FishFeats/
September 4, 2025 at 4:07 PM
It was great to be there! A big thank you to all of those who made it possible!
More than 3,000 ESC Volunteers make possible everything the ESC does – from congresses guidelines and journals to data science, education, public health advocacy and more.

Thank you for giving the global CV healthcare community, and patients, the gift of time.

#ESCCongress #ESC75Years #ESCTV
September 2, 2025 at 2:12 PM
It was great to present our latest data at #ESC Congress in #Madrid and to catch up with colleagues and friends at one of the most important cardiology conferences! Huge event with great science and clinical data + Madrid is a nice city! @eassociety.bsky.social #moncyte-health #cholesterol #CVD
September 2, 2025 at 2:06 PM
It was very nice recording this podcast and talking about our research at @helsinki.fi and forming the startup company www.moncytehealth.com!
August 25, 2025 at 5:19 AM
Reposted by Simon Pfisterer
Today, our article "The entities enabling scientific fraud at scale are large, resilient, and growing rapidly" is finally published in PNAS. I hope that it proves to be a wake-up-call for the whole scientific community.

reeserichardson.blog/2025/08/04/a...
A do-or-die moment for the scientific enterprise
Reflecting on our paper “The entities enabling scientific fraud at scale are large, resilient, and growing rapidly”
reeserichardson.blog
August 4, 2025 at 8:47 PM
Reposted by Simon Pfisterer
It’s official, we’ve acquired Geost! Adding space-based missile defense, space protection & space domain awareness sensors to our extensive portfolio of capabilities, securing the technology needed for next-generation defense initiatives & U.S. national security missions - bit.ly/3UmNjRF
August 12, 2025 at 12:48 PM
Science and innovation are bringing humankind forward. With positive impact on jobs, tax revenue, health and wellbeing. @helsinki.fi and other universities in Finland and around the globe are great examples. Support in them is crucial. Like a seed turning into a great flower!
August 7, 2025 at 2:39 PM
Reposted by Simon Pfisterer
I’m happy that research and development in Germany 🇩🇪 are striving - still so many things to do adopt an open and inclusive culture at German universities.
August 4, 2025 at 9:07 AM
Reposted by Simon Pfisterer
As rates of obesity and related metabolic disorders continue to rise globally, the need for an integrated approach to care has never been greater. Join our webinar & learn how this three-stage model offers a holistic strategy for risk reduction, with clear criteria at each step: eas.to/WebOct21Reg
August 4, 2025 at 10:23 AM
Reposted by Simon Pfisterer
Some journals are claiming that you need to pay big $$ for gold open access to comply with NIH's new public access policy. FYI that is total bs. You can comply by depositing the Accepted Manuscript into PubMed Central on the Date of Publication without embargo. Pass it on.
July 26, 2025 at 12:52 AM
Reposted by Simon Pfisterer
🚨 One week left to apply!
I am hiring a fully funded PhD fellow and a postdoc to work on membrane protein structural biology and pharmacology at Univ Copenhagen

Come work with a great team and exciting projects in a collaborative environment!

🔗 Links to the ads in comments

#CryoEM #AcademicJobs
August 3, 2025 at 8:21 PM
Reposted by Simon Pfisterer
BioLabs|TUM, a new #biotechnology hub launched by TUM Venture Labs, BioLabs, and Eli Lilly and Company, will open in 2026 in central #Munich. The site will offer lab space, mentoring and networks to early-stage #startups: go.tum.de/297087

#Entrepreneurship

📷BioLabs
BioLabs|TUM launched to foster start-ups
The TUM Venture Labs, BioLabs and Eli Lilly and Company (Lilly) today launched BioLabs|TUM, a new biotechnology innovation hub.
go.tum.de
August 4, 2025 at 2:03 PM