Simon Richardson
@simonrichardson.bsky.social
Clinician Scientist and Consultant Haematologist | Researches stem cell biology, epigenetics and drug discovery, specialising in B-ALL | Fellow St Catharine's College, Cambridge
Pinned
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition - Nature Communications
CREBBP mutations in B-cell acute lymphoblastic leukemia (B-ALL) are linked to poor prognosis and chemoresistance. Here, the authors show that genetic or pharmacological inactivation of CREBBP sensitiz...
www.nature.com
Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com. 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Simon Richardson
A decade of bold ideas, brilliant minds & real impact. 💡
Our John Goldman Fellowships are driving progress in leukaemia research, from identifying new drug targets to repurposing existing medicines.
Read more: www.leukaemiauk.org.uk/stories/a-de...
Our John Goldman Fellowships are driving progress in leukaemia research, from identifying new drug targets to repurposing existing medicines.
Read more: www.leukaemiauk.org.uk/stories/a-de...
A decade of progress and impact - Leukaemia UK
This October marks ten years since Leukaemia UK launched its John Goldman Fellowship (JGF) programme. In this blog, and the next, we’ll explore its impact and successes.
www.leukaemiauk.org.uk
October 30, 2025 at 5:35 PM
A decade of bold ideas, brilliant minds & real impact. 💡
Our John Goldman Fellowships are driving progress in leukaemia research, from identifying new drug targets to repurposing existing medicines.
Read more: www.leukaemiauk.org.uk/stories/a-de...
Our John Goldman Fellowships are driving progress in leukaemia research, from identifying new drug targets to repurposing existing medicines.
Read more: www.leukaemiauk.org.uk/stories/a-de...
On my way back from a fabulous day of science and catching up with friends and colleagues at the UKALL Research Network update day. Great to see so much progress. 👍
October 10, 2025 at 6:34 PM
On my way back from a fabulous day of science and catching up with friends and colleagues at the UKALL Research Network update day. Great to see so much progress. 👍
Reposted by Simon Richardson
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
October 7, 2025 at 5:49 PM
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r
Reposted by Simon Richardson
Great to host our new @stcatharines.bsky.social medics before their first college dinner 🩺😷🚑🩻⚕️
October 6, 2025 at 6:28 PM
Great to host our new @stcatharines.bsky.social medics before their first college dinner 🩺😷🚑🩻⚕️
Thank you @leukaemiauk.bsky.social for the invitation to #WCD2025. 😋 It was great to share some of our work and humbling to hear the story of 4 year old Billie the Brave. Congrats on raising so much in one evening for life changing leukaemia research! ❤️
September 16, 2025 at 3:21 PM
Thank you @leukaemiauk.bsky.social for the invitation to #WCD2025. 😋 It was great to share some of our work and humbling to hear the story of 4 year old Billie the Brave. Congrats on raising so much in one evening for life changing leukaemia research! ❤️
Thanks to @leukaemiauk.bsky.social for the opportunity to contribute to this amazing session. So important to link patient experiences with our science and translational research
An incredibly inspiring and thought-provoking Q&A session with some of our John Goldman Fellows and Leukaemia UK Community Champions. ✨
@simonrichardson.bsky.social @scicambridge.bsky.social @manchester.ac.uk @uom-dcs.bsky.social
@simonrichardson.bsky.social @scicambridge.bsky.social @manchester.ac.uk @uom-dcs.bsky.social
September 4, 2025 at 5:21 PM
Thanks to @leukaemiauk.bsky.social for the opportunity to contribute to this amazing session. So important to link patient experiences with our science and translational research
Reposted by Simon Richardson
💙 Between now & the UCAS application deadline on 15 Oct, it’s worth checking if you're eligible for the Finlay Family Bursary, which covers all tuition fees & a living allowance for a St Catharine’s student from Scotland for all 3 or 4 years of an undergraduate degree: shorturl.at/K0RuE 3/3
The Finlay Family Bursary for Scottish undergraduates
We are proud to offer this bursary to encourage Scottish students to apply for, and take up, the offer of an undergraduate place at St Catharine’s – an opportunity which would normally involve greater financial cost than attending a Scottish university.
shorturl.at
August 5, 2025 at 9:15 AM
💙 Between now & the UCAS application deadline on 15 Oct, it’s worth checking if you're eligible for the Finlay Family Bursary, which covers all tuition fees & a living allowance for a St Catharine’s student from Scotland for all 3 or 4 years of an undergraduate degree: shorturl.at/K0RuE 3/3
Reposted by Simon Richardson
LS, an emergent form of acute leukemia relapse after antigen-targeted therapy, primarily in B-ALL, has dismal outcomes. buff.ly/59xI6qv #hemesky
July 30, 2025 at 1:02 PM
LS, an emergent form of acute leukemia relapse after antigen-targeted therapy, primarily in B-ALL, has dismal outcomes. buff.ly/59xI6qv #hemesky
Reposted by Simon Richardson
I’m looking for a Postdoc to join my new lab @pdncambridge.bsky.social on an MRC-funded project and explore maternal inter-organ communication with a focus on the mammary gland, using a novel mouse model.
📍 Tenure: 3 years
⏳ Deadline: 15 August 2025
Please RT 🙏
👉 www.jobs.cam.ac.uk/job/51984/
📍 Tenure: 3 years
⏳ Deadline: 15 August 2025
Please RT 🙏
👉 www.jobs.cam.ac.uk/job/51984/
Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Associate (Fixed Term) in the Department of Physiology, Development and Neuroscience at the University of Cambridge.
www.jobs.cam.ac.uk
July 14, 2025 at 6:48 PM
I’m looking for a Postdoc to join my new lab @pdncambridge.bsky.social on an MRC-funded project and explore maternal inter-organ communication with a focus on the mammary gland, using a novel mouse model.
📍 Tenure: 3 years
⏳ Deadline: 15 August 2025
Please RT 🙏
👉 www.jobs.cam.ac.uk/job/51984/
📍 Tenure: 3 years
⏳ Deadline: 15 August 2025
Please RT 🙏
👉 www.jobs.cam.ac.uk/job/51984/
No trains? No problem! Wacky races down to The City of London with these amazing @crukcamcentre.bsky.social entrepreneurial scientists just in time for the CRUK Innovation and Enterprise awards. Thank you @crhorizons.bsky.social 🥂🎉🙏
July 11, 2025 at 10:00 PM
No trains? No problem! Wacky races down to The City of London with these amazing @crukcamcentre.bsky.social entrepreneurial scientists just in time for the CRUK Innovation and Enterprise awards. Thank you @crhorizons.bsky.social 🥂🎉🙏
Absolute honour to attend Marc Mansour’s @marcmansour.bsky.social inaugural lecture at ICH today. An inspiring clinician scientist and all round legend. #researchculture
July 9, 2025 at 10:59 PM
Absolute honour to attend Marc Mansour’s @marcmansour.bsky.social inaugural lecture at ICH today. An inspiring clinician scientist and all round legend. #researchculture
Really exciting to co-organise the 20 year graduation reunion for Oxford medical school last night. Wonderful to reunite with old friends and hear retired DoS Tim Lancaster speak powerfully about how caring is at the heart of good medicine 💊❤️
July 6, 2025 at 8:00 AM
Really exciting to co-organise the 20 year graduation reunion for Oxford medical school last night. Wonderful to reunite with old friends and hear retired DoS Tim Lancaster speak powerfully about how caring is at the heart of good medicine 💊❤️
Reposted by Simon Richardson
Best night of the year !
Farewell dinner for the new doctors from @stcatharines.bsky.social
Interviewed them 7 years ago.
Watched them blossom for 6 years.
Now they’re amazing!
Farewell dinner for the new doctors from @stcatharines.bsky.social
Interviewed them 7 years ago.
Watched them blossom for 6 years.
Now they’re amazing!
June 13, 2025 at 9:11 PM
Best night of the year !
Farewell dinner for the new doctors from @stcatharines.bsky.social
Interviewed them 7 years ago.
Watched them blossom for 6 years.
Now they’re amazing!
Farewell dinner for the new doctors from @stcatharines.bsky.social
Interviewed them 7 years ago.
Watched them blossom for 6 years.
Now they’re amazing!
Thanks to the editorial team @natcomms.nature.com for including our recent paper in their Editors' Highlights in the field of Cancer Biology 🎉
Editors' Highlights | Nature Communications
Editors' Highlights
eur03.safelinks.protection.outlook.com
June 11, 2025 at 8:25 AM
Thanks to the editorial team @natcomms.nature.com for including our recent paper in their Editors' Highlights in the field of Cancer Biology 🎉
Reposted by Simon Richardson
I wrote a new piece on how much progress has been made in treating childhood leukemia.
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
June 9, 2025 at 7:43 AM
I wrote a new piece on how much progress has been made in treating childhood leukemia.
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
The answer is: quite a lot!
Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.
Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...
What an inspiring evening hearing from patients, researchers and fundraisers at an Evening with Leukaemia UK.
So much progress. So much to do
@leukaemiauk.bsky.social
So much progress. So much to do
@leukaemiauk.bsky.social
June 9, 2025 at 10:46 PM
What an inspiring evening hearing from patients, researchers and fundraisers at an Evening with Leukaemia UK.
So much progress. So much to do
@leukaemiauk.bsky.social
So much progress. So much to do
@leukaemiauk.bsky.social
Thanks to Chris Smith and the Naked Scientists for the invitation to discuss our work - fully clothed 🤓
www.thenakedscientists.com/articles/int...
www.thenakedscientists.com/articles/int...
Dual drug approach shows promise against childhood cancer
On the B-ALL...
www.thenakedscientists.com
May 24, 2025 at 11:02 AM
Thanks to Chris Smith and the Naked Scientists for the invitation to discuss our work - fully clothed 🤓
www.thenakedscientists.com/articles/int...
www.thenakedscientists.com/articles/int...
And that’s a wrap. 20 supervisons in biochemistry and genetics for the Catz @stcatharines.bsky.social first year medics. Good luck in the exams!
May 22, 2025 at 3:49 PM
And that’s a wrap. 20 supervisons in biochemistry and genetics for the Catz @stcatharines.bsky.social first year medics. Good luck in the exams!
Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com. 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
CREBBP inactivation sensitizes B cell acute lymphoblastic leukemia to ferroptotic cell death upon BCL2 inhibition - Nature Communications
CREBBP mutations in B-cell acute lymphoblastic leukemia (B-ALL) are linked to poor prognosis and chemoresistance. Here, the authors show that genetic or pharmacological inactivation of CREBBP sensitiz...
www.nature.com
May 20, 2025 at 9:34 AM
Delighted that our work describing a potential novel treatment approach for B-cell Acute Lymphoblastic Leukaemia is published today in @natcomms.nature.com. 🧵
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Simon Richardson
We were delighted to welcome Lord Vallance, Minister of State for Science, last week. Hala Al-Haboubi (a 3rd-year medical student at Catz) said, "Lord Vallance shared inspirational, forward-looking insights about the future of scientific research. It was a real privilege to hear from him!" 1/3
May 9, 2025 at 8:25 AM
We were delighted to welcome Lord Vallance, Minister of State for Science, last week. Hala Al-Haboubi (a 3rd-year medical student at Catz) said, "Lord Vallance shared inspirational, forward-looking insights about the future of scientific research. It was a real privilege to hear from him!" 1/3
