Silva Pereira Lab (Parasite Vascular Interactions)
@silvapereiralab.bsky.social
Lab @ Católica Biomed Research Centre (Lisbon - PT)
using cool tech to discover how parasites interact with blood vessels
silvapereiralab.com
using cool tech to discover how parasites interact with blood vessels
silvapereiralab.com
Pinned
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Communications Biology - Organ-specific bioengineered microvessels and animal models reveal that Trypanosoma congolense sequestration depends on the endothelial cell bed, parasite strain, cyclic...
rdcu.be
Here's a short summary of our most recent paper, published today on @commsbio.bsky.social:
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
The #EMBOWorkshop : Host–parasite relationship has come to a close! Thank you to all speakers, participants, and organizers for four inspiring days of science, discussion, and human connection. Until next time! 🧫✨
October 8, 2025 at 11:32 AM
The #EMBOWorkshop : Host–parasite relationship has come to a close! Thank you to all speakers, participants, and organizers for four inspiring days of science, discussion, and human connection. Until next time! 🧫✨
Our amazing student @leonorloira.bsky.social presented some of the lab’s work today at the @parafrap.bsky.social #EMBOconference
We are very proud.
We are very proud.
October 7, 2025 at 10:06 AM
Our amazing student @leonorloira.bsky.social presented some of the lab’s work today at the @parafrap.bsky.social #EMBOconference
We are very proud.
We are very proud.
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
Our lab has two funded PhDs to start in 2026 via the NorthWestBio programme
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Understanding Pathogens, from Molecules to Phenotypes - Richard McCulloch
www.gla.ac.uk
October 6, 2025 at 1:23 PM
Our lab has two funded PhDs to start in 2026 via the NorthWestBio programme
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Project details here
www.gla.ac.uk/postgraduate...
...and here
www.gla.ac.uk/postgraduate...
Application deadline is Nov 21st 2025; apply here:
www.gla.ac.uk/postgraduate...
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...
July 11, 2025 at 7:31 PM
Pre-print alert 🚨: We have developed 2D and 3D stable iPSC endothelial-differentiation models through dox inducible ETS expression. We demonstrate endothelial identity and used these models for studying malaria pathogenesis research. www.biorxiv.org/content/10.1...
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on!
innovativegenomics.org/news/first-p...
innovativegenomics.org/news/first-p...
First Patient Treated with Personalized CRISPR Therapy, Developed in Just Six Months
The first on-demand CRISPR therapy for an infant with a rare metabolic disease developed by the IGI and collaborators around the world.
innovativegenomics.org
May 15, 2025 at 5:40 PM
This is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on!
innovativegenomics.org/news/first-p...
innovativegenomics.org/news/first-p...
Here’s our latest revision of microphysiological systems in parasitology research, published in @plos.org #plospathogens in collaboration with Jorge de-Carvalho (ITQB-NOVA) and @mariabernabeu.bsky.social. Kudos to @mariazalmeida.bsky.social, PhD student, for the heavy lifting of this work.
Leveraging microphysiological systems to expedite understanding of host–parasite interactions
Microphysiological systems (MPS) replicate the dynamic interactions between cells, tissues, and fluids. They have emerged as transformative tools for biology and have been increasingly applied to host...
journals.plos.org
May 4, 2025 at 9:24 PM
Here’s our latest revision of microphysiological systems in parasitology research, published in @plos.org #plospathogens in collaboration with Jorge de-Carvalho (ITQB-NOVA) and @mariabernabeu.bsky.social. Kudos to @mariazalmeida.bsky.social, PhD student, for the heavy lifting of this work.
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
Join us for our next TrypsClub Journal Club!
Next @bspparasitology.bsky.social TrypsClub Journal Club will take place online on 2nd April - all students, research assistants, postdocs and techs are welcome! Discussing a paper form the Mugnier lab group, featuring a Q&A with Moinca! Sign up here - tinyurl.com/5n6pme36
1. TrypsClub Journal Club Registration
We are pleased to invite you to the second BSP supported TrypsClub meeting!
2nd April, 2 pm (GMT)
Our aim is to bring together ...
tinyurl.com
March 25, 2025 at 2:39 PM
Join us for our next TrypsClub Journal Club!
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
Why the world needs a vision for public health now more than ever
LSHTM Director Liam Smeeth argues #PublicHealth research & education are even more important with #science under attack & global #health programmes facing unprecedented cuts.
www.lshtm.ac.uk/newsevents/e...
LSHTM Director Liam Smeeth argues #PublicHealth research & education are even more important with #science under attack & global #health programmes facing unprecedented cuts.
www.lshtm.ac.uk/newsevents/e...
March 13, 2025 at 12:51 PM
Why the world needs a vision for public health now more than ever
LSHTM Director Liam Smeeth argues #PublicHealth research & education are even more important with #science under attack & global #health programmes facing unprecedented cuts.
www.lshtm.ac.uk/newsevents/e...
LSHTM Director Liam Smeeth argues #PublicHealth research & education are even more important with #science under attack & global #health programmes facing unprecedented cuts.
www.lshtm.ac.uk/newsevents/e...
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
Tragically, A child has died of measles in Texas. Cases of measles continue to grow in Texas & elsewhere in USA. Please seriously consider vaccinating your child with the MMR vaccine which is safe & effective. Outbreaks at this scale are NOT normal & is facilitated by high pptn of unvaccinated kids
A child is dead from measles.
5 things on my mind and answers to your questions
yourlocalepidemiologist.substack.com
February 27, 2025 at 7:54 AM
Tragically, A child has died of measles in Texas. Cases of measles continue to grow in Texas & elsewhere in USA. Please seriously consider vaccinating your child with the MMR vaccine which is safe & effective. Outbreaks at this scale are NOT normal & is facilitated by high pptn of unvaccinated kids
Here's a short summary of our most recent paper, published today on @commsbio.bsky.social:
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Communications Biology - Organ-specific bioengineered microvessels and animal models reveal that Trypanosoma congolense sequestration depends on the endothelial cell bed, parasite strain, cyclic...
rdcu.be
February 27, 2025 at 9:53 AM
Here's a short summary of our most recent paper, published today on @commsbio.bsky.social:
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
We want to understand how Trypanosoma congolense cytoadheres, or sequesters, to the vascular endothelium because sequestration determines clinical outcome and disease severity.
(1/7)
The lab's first original research article presenting a novel microfluidic 3D model of bovine vasculature and discussing how T. congolense attaches to blood vessels is now published. But before I discuss the work, I'd like to thank key people who made it possible. (1/5)
Bioengineered 3D microvessels and complementary animal models reveal mechanisms of Trypanosoma congolense sequestration
Communications Biology - Organ-specific bioengineered microvessels and animal models reveal that Trypanosoma congolense sequestration depends on the endothelial cell bed, parasite strain, cyclic...
rdcu.be
February 27, 2025 at 9:30 AM
The lab's first original research article presenting a novel microfluidic 3D model of bovine vasculature and discussing how T. congolense attaches to blood vessels is now published. But before I discuss the work, I'd like to thank key people who made it possible. (1/5)
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
We are very excited to announce a new @events.embl.org conference with a general focus on all infections with the goal to foster discussions across researchers working on multiple pathogens. We couldn't find a conference as such in Europe, so we decided to organize it 😊
www.embl.org/about/info/c...
www.embl.org/about/info/c...
December 20, 2024 at 9:53 AM
We are very excited to announce a new @events.embl.org conference with a general focus on all infections with the goal to foster discussions across researchers working on multiple pathogens. We couldn't find a conference as such in Europe, so we decided to organize it 😊
www.embl.org/about/info/c...
www.embl.org/about/info/c...
Great opportunity with a great team!
I'm looking for a research technician! If you're interested in studying how malaria gametocytes remodel their host cell come join us on a @wellcometrust.bsky.social funded project at GIMM by applying here: gimm.pt/jobs/laborat...
Deadline 20th December. Please share!
Deadline 20th December. Please share!
Laboratory Technician – GIMMLaboratory Technician – GIMM
GIMM is recruiting a Laboratory Technician under an Employment Contract – Reference GIMM/CT/35-2024
gimm.pt
December 3, 2024 at 4:10 PM
Great opportunity with a great team!
Reposted by Silva Pereira Lab (Parasite Vascular Interactions)
People who claim things like “HIV doesn’t cause AIDS” have a fundamental lack of understanding of how scientific knowledge accrues and often are prone to medical conspiracism.
Read more ⬇️
news.immunologic.org/p/viruses-ar...
Read more ⬇️
news.immunologic.org/p/viruses-ar...
Viruses are Real, No Matter What Joe Rogan and RFK Jr. Say
Germ theory denialism has been around since the 1800s, but it's promoted today by pseudoscience conspiracy theorists
news.immunologic.org
November 23, 2024 at 8:05 AM
People who claim things like “HIV doesn’t cause AIDS” have a fundamental lack of understanding of how scientific knowledge accrues and often are prone to medical conspiracism.
Read more ⬇️
news.immunologic.org/p/viruses-ar...
Read more ⬇️
news.immunologic.org/p/viruses-ar...
Our first post is an advert for the lab’s first official original research paper:
www.researchsquare.com/article/rs-5...
www.researchsquare.com/article/rs-5...
Bioengineered 3D microvessels reveal novel determinants of Trypanosoma congolense sequestration
In the mammalian host, Trypanosoma congolense cytoadheres to the vascular endothelium in a process known as sequestration. Although sequestration influences clinical outcome, disease severity and orga...
www.researchsquare.com
November 18, 2024 at 11:10 PM
Our first post is an advert for the lab’s first official original research paper:
www.researchsquare.com/article/rs-5...
www.researchsquare.com/article/rs-5...