Siddharth Jayakumar
@siddjakes.bsky.social
Neuroscientist. Postdoc. Drummer
Reposted by Siddharth Jayakumar
Happy to see this collaboration with @neurovenki.bsky.social out - featuring great work by Juan Carlos!
Excited to share new computational work, led by @jzv.bsky.social, driven by Juan Carlos Fernandez del Castillo + contribution from Farhad Pashakanloo. We recover 3 core motifs in the olfactory system of evolutionarily distant animals using a biophysically-grounded model + efficient coding ideas!
Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding
The architecture of early olfactory processing is a striking example of convergent evolution. Typically, a panel of broadly tuned receptors is selectively expressed in sensory neurons (each neuron exp...
www.biorxiv.org
September 4, 2025 at 6:24 PM
Happy to see this collaboration with @neurovenki.bsky.social out - featuring great work by Juan Carlos!
Reposted by Siddharth Jayakumar
Excited to share new computational work, led by @jzv.bsky.social, driven by Juan Carlos Fernandez del Castillo + contribution from Farhad Pashakanloo. We recover 3 core motifs in the olfactory system of evolutionarily distant animals using a biophysically-grounded model + efficient coding ideas!
Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding
The architecture of early olfactory processing is a striking example of convergent evolution. Typically, a panel of broadly tuned receptors is selectively expressed in sensory neurons (each neuron exp...
www.biorxiv.org
September 4, 2025 at 4:51 PM
Excited to share new computational work, led by @jzv.bsky.social, driven by Juan Carlos Fernandez del Castillo + contribution from Farhad Pashakanloo. We recover 3 core motifs in the olfactory system of evolutionarily distant animals using a biophysically-grounded model + efficient coding ideas!
Excited to share our latest!! Thanks to everyone involved especially @neurovenki.bsky.social!
Thrilled to share this work, long time in the making! Carried through creatively by @siddjakes.bsky.social after initial design & piloting by @trackingskills.bsky.social, with help from @trackingactions.bsky.social. Modeling in collaboration with Massimo Vergassola & Nicola Rigolli.
Mice navigate scent trails using predictive policies
Animals actively sense their environment to extract features of interest to guide behaviors. For mammals, odors are prominent environmental features which are sampled by active modulation of sniffing ...
www.biorxiv.org
September 2, 2025 at 3:38 PM
Excited to share our latest!! Thanks to everyone involved especially @neurovenki.bsky.social!
Reposted by Siddharth Jayakumar
Happy to share our latest preprint! Very thankful of this project that have allowed me to (1) learn a lot, (2) work with very talented and rigorous people, and (3) capitalize 1 and 2 for delving into how mice olfactory system deals with very brief, intermittent odor stimuli.
Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪
Perception and neural representation of intermittent odor stimuli in mice
Odor cues in nature are sparse and highly fluctuating due to turbulent transport. To investigate how animals perceive these intermittent cues, we developed a behavioral task in which head-restrained m...
www.biorxiv.org
February 13, 2025 at 8:44 PM
Happy to share our latest preprint! Very thankful of this project that have allowed me to (1) learn a lot, (2) work with very talented and rigorous people, and (3) capitalize 1 and 2 for delving into how mice olfactory system deals with very brief, intermittent odor stimuli.
Reposted by Siddharth Jayakumar
Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪
Perception and neural representation of intermittent odor stimuli in mice
Odor cues in nature are sparse and highly fluctuating due to turbulent transport. To investigate how animals perceive these intermittent cues, we developed a behavioral task in which head-restrained m...
www.biorxiv.org
February 13, 2025 at 6:34 PM
Yes, many worrying things happening in science that should take priority in grabbing our attention - but we are worried precisely because scientific knowledge is worth creating. In that spirit, I am proud to highlight our latest @biorxivpreprint.bsky.social preprint! #neuroscience 🧪
For folks attending #Cosyne24, do check out the workshop Anqi Zhang and I are organizing:"Comparative approaches to advance neural circuits and computation". It's on March 4th!
February 29, 2024 at 2:08 PM
For folks attending #Cosyne24, do check out the workshop Anqi Zhang and I are organizing:"Comparative approaches to advance neural circuits and computation". It's on March 4th!
Reposted by Siddharth Jayakumar
Engineered odorant receptors illuminate structural principles of odor discrimination https://www.biorxiv.org/content/10.1101/2023.11.16.567230v1
Engineered odorant receptors illuminate structural principles of odor discrimination https://www.biorxiv.org/content/10.1101/2023.11.16.567230v1
A central challenge in olfaction is understanding how the olfactory system detects and distinguishes
www.biorxiv.org
November 17, 2023 at 11:15 PM
Engineered odorant receptors illuminate structural principles of odor discrimination https://www.biorxiv.org/content/10.1101/2023.11.16.567230v1