Nitzan Shabek
@shabeklab.bsky.social
Prof. @UC Davis ∙structural biologist⚛︎ ubiquitin system aficionado ✾ signaling & sensing mechanisms in plants🌱in vivo interacomes 🎸dad of 2
https://shabek-lab.ucdavis.edu/
https://shabek-lab.ucdavis.edu/
Pinned
Nitzan Shabek
@shabeklab.bsky.social
· Nov 16
Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...
rdcu.be
our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l
rdcu.be/d0s6l
excited to be part of this study published @pnas.org led by the wonderful Caroline Gutjahr 👏revealing how the GRAS protein RAM1 partners with WRI transcription factors to regulate genes essential for arbuscule formation & nutrient exchange in plant-fungal symbiosis www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
May 19, 2025 at 8:01 PM
excited to be part of this study published @pnas.org led by the wonderful Caroline Gutjahr 👏revealing how the GRAS protein RAM1 partners with WRI transcription factors to regulate genes essential for arbuscule formation & nutrient exchange in plant-fungal symbiosis www.pnas.org/doi/10.1073/...
Reposted by Nitzan Shabek
Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cell-autonomous innate immunity by proteasome-derived defence peptides - Nature
Proteasomal degradation of cellular proteins generate defence peptides constitutively and in response to bacterial infection. Such peptides might provide a source of natural antibiotics that...
www.nature.com
March 5, 2025 at 7:46 PM
Wow! The Proteasome generates antimicrobial peptides that directly affect bacterial membranes #proteostasis
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Nitzan Shabek
🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?
March 1, 2025 at 11:06 PM
🧪what with the demolition of #NIH funded #research, where, dare I ask, are our friends from #bigpharma? y'all good? mooched enough off of public-access NIH-funded research? Stocked up with PhD level scientists who were trained on NIH training grants to tide you over until Academia comes back?
Super excited to contribute to this amazing work on the evolution of interorganismal strigolactone biosynthesis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Evolution of interorganismal strigolactone biosynthesis in seed plants
Strigolactones (SLs) are methylbutenolide molecules derived from β-carotene through an intermediate carlactonoic acid (CLA). Canonical SLs act as signals to microbes and plants, whereas noncanonical S...
www.science.org
January 18, 2025 at 3:52 AM
Super excited to contribute to this amazing work on the evolution of interorganismal strigolactone biosynthesis
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Nitzan Shabek
New to #ubiquitin? Been with it for a while? Either way this review may be for you 🤩
Excited to share our review article in @molcell.bsky.social, diving deep into everything #ubiquitin
Read here 👉: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
@cellpress.bsky.social
@wehi-research.bsky.social
Excited to share our review article in @molcell.bsky.social, diving deep into everything #ubiquitin
Read here 👉: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
@cellpress.bsky.social
@wehi-research.bsky.social
January 17, 2025 at 2:19 AM
New to #ubiquitin? Been with it for a while? Either way this review may be for you 🤩
Excited to share our review article in @molcell.bsky.social, diving deep into everything #ubiquitin
Read here 👉: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
@cellpress.bsky.social
@wehi-research.bsky.social
Excited to share our review article in @molcell.bsky.social, diving deep into everything #ubiquitin
Read here 👉: kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
@cellpress.bsky.social
@wehi-research.bsky.social
Reposted by Nitzan Shabek
🆕 Our Latest Issue is online now!
📚 nph.onlinelibrary.wiley.com/toc/14698137...
Highlights:
🌱 Announcing the 2024 Tansley Medal winner
🌱 Unravelling plant centromeres
🌱 Is auxin the key to improve crop nitrogen efficiency?
🌱 Vegetation responses to moisture conditions
📚 nph.onlinelibrary.wiley.com/toc/14698137...
Highlights:
🌱 Announcing the 2024 Tansley Medal winner
🌱 Unravelling plant centromeres
🌱 Is auxin the key to improve crop nitrogen efficiency?
🌱 Vegetation responses to moisture conditions
New Phytologist: Vol 244, No 6
<em>New Phytologist</em> is an international journal owned by the New Phytologist Foundation publishing original research in plant science and its applications.
nph.onlinelibrary.wiley.com
November 21, 2024 at 9:26 AM
🆕 Our Latest Issue is online now!
📚 nph.onlinelibrary.wiley.com/toc/14698137...
Highlights:
🌱 Announcing the 2024 Tansley Medal winner
🌱 Unravelling plant centromeres
🌱 Is auxin the key to improve crop nitrogen efficiency?
🌱 Vegetation responses to moisture conditions
📚 nph.onlinelibrary.wiley.com/toc/14698137...
Highlights:
🌱 Announcing the 2024 Tansley Medal winner
🌱 Unravelling plant centromeres
🌱 Is auxin the key to improve crop nitrogen efficiency?
🌱 Vegetation responses to moisture conditions
Excited to share that our research on the SCF E3 ubiquitin ligase interactome in plants is now published in New Phytologist and featured as the cover of the current issue! 🌱 @newphyt.bsky.social #ubiquitin #proteostasis
nph.onlinelibrary.wiley.com/share/CA8XRQ...
nph.onlinelibrary.wiley.com/share/CA8XRQ...
November 21, 2024 at 4:40 PM
Excited to share that our research on the SCF E3 ubiquitin ligase interactome in plants is now published in New Phytologist and featured as the cover of the current issue! 🌱 @newphyt.bsky.social #ubiquitin #proteostasis
nph.onlinelibrary.wiley.com/share/CA8XRQ...
nph.onlinelibrary.wiley.com/share/CA8XRQ...
Reposted by Nitzan Shabek
I made a starter pack for the plant proteostasis community - please let me know if I missed someone to add new members #proteostasis
November 20, 2024 at 7:25 AM
I made a starter pack for the plant proteostasis community - please let me know if I missed someone to add new members #proteostasis
Reposted by Nitzan Shabek
The email announcement of International Plant Growth Substances Association (IPGSA) Conference in 2025 in Fort Collins, Colorado, USA is just out! Please spread the word of what will be a very exciting conference in a beautiful place. #IPGSA2025
November 20, 2024 at 7:20 PM
The email announcement of International Plant Growth Substances Association (IPGSA) Conference in 2025 in Fort Collins, Colorado, USA is just out! Please spread the word of what will be a very exciting conference in a beautiful place. #IPGSA2025
Reposted by Nitzan Shabek
Final version of or single-cell proteomics paper is now published in the New Phytologist December issue! @dormichicken.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com/doi/10.1111/...
Single‐cell proteomics differentiates Arabidopsis root cell types
See also the Commentary on this article by van Schie & Weijers, 244: 1678–1680.
nph.onlinelibrary.wiley.com
November 10, 2024 at 8:17 PM
Final version of or single-cell proteomics paper is now published in the New Phytologist December issue! @dormichicken.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...
nph.onlinelibrary.wiley.com/doi/10.1111/...
Reposted by Nitzan Shabek
our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l
rdcu.be/d0s6l
Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...
rdcu.be
November 16, 2024 at 9:20 PM
our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l
rdcu.be/d0s6l
Reposted by Nitzan Shabek
Should've done this a long time ago, but here's my first post on #Bluesky.
Check out my postdoc paper on a bacterial ubiquitin-like defense system that we recently published!
www.nature.com/articles/s41...
Check out my postdoc paper on a bacterial ubiquitin-like defense system that we recently published!
www.nature.com/articles/s41...
Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly - Nature
To mitigate phage infection, an antiphage defence system in bacteria conjugates a ubiquitin-like protein to a structural protein of the phage, demonstrating that conjugation of ubiquiti...
www.nature.com
November 11, 2024 at 4:16 PM
Should've done this a long time ago, but here's my first post on #Bluesky.
Check out my postdoc paper on a bacterial ubiquitin-like defense system that we recently published!
www.nature.com/articles/s41...
Check out my postdoc paper on a bacterial ubiquitin-like defense system that we recently published!
www.nature.com/articles/s41...
Reposted by Nitzan Shabek
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn
November 15, 2024 at 7:38 PM
Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn
Reposted by Nitzan Shabek
I direct the UC Davis Biotechnology Program - looking forward to building #academicsky community! 🧬🧫🔬🧪🥼#ucdavis #biotech
November 14, 2024 at 6:51 PM
I direct the UC Davis Biotechnology Program - looking forward to building #academicsky community! 🧬🧫🔬🧪🥼#ucdavis #biotech
our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l
rdcu.be/d0s6l
Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
Nature Communications - Plant hormone levels are regulated by synthesis and breakdown, but the mechanism of strigolactone degradation remains unclear. This study reveals the structure of distinct...
rdcu.be
November 16, 2024 at 9:20 PM
our latest work @natureportfolio.bsky.social nature communications: Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation
rdcu.be/d0s6l
rdcu.be/d0s6l
molecular basis of SCOOP perception by the MIK2–BAK1 immune complex rdcu.be/d0s5E
Mechanistic study of SCOOPs recognition by MIK2–BAK1 complex reveals the role of N-glycans in plant ligand–receptor–coreceptor complex formation
Nature Plants - Wu et al. elucidate the molecular basis for SCOOPs perception by the MIK2–BAK1 immune complex and demonstrate an unexpectedly pivotal role of N-glycans in plant...
rdcu.be
November 16, 2024 at 9:14 PM
molecular basis of SCOOP perception by the MIK2–BAK1 immune complex rdcu.be/d0s5E