Sebastian Oehm
@sebastianoehm.bsky.social
Synthetic biology, biosecurity, therapeutics
Reposted by Sebastian Oehm
Sharing here a new commentary in Science Policy Forum that provides new analysis on risks related to the potential future creation of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’). 1/x
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
www.science.org
December 12, 2024 at 7:30 PM
Sharing here a new commentary in Science Policy Forum that provides new analysis on risks related to the potential future creation of mirror bacteria — synthetic organisms in which all molecules have reversed chirality (i.e. are ‘mirrored’). 1/x
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Sebastian Oehm
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report:
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
December 12, 2024 at 7:05 PM
I’m proud to join more than 30 colleagues today in sharing our analysis of potential risks from “mirror life”. We summarize our findings in a @science.org article, and in greater detail in a 300pg technical report:
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Article: www.science.org/doi/10.1126/...
Report: purl.stanford.edu/cv716pj4036
Reposted by Sebastian Oehm
Shareable link to @carlzimmer.bsky.social article in NYTimes on serious concerns over mirror bacteria, published in Science today.
www.nytimes.com/2024/12/12/s...
www.nytimes.com/2024/12/12/s...
A ‘Second Tree of Life’ Could Wreak Havoc, Scientists Warn (Gift Article)
Research on so-called mirror cells, which defy fundamental properties of living organisms, should be prohibited as too dangerous, biologists said.
www.nytimes.com
December 12, 2024 at 7:51 PM
Shareable link to @carlzimmer.bsky.social article in NYTimes on serious concerns over mirror bacteria, published in Science today.
www.nytimes.com/2024/12/12/s...
www.nytimes.com/2024/12/12/s...
Reposted by Sebastian Oehm
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Confronting risks of mirror life
Broad discussion is needed to chart a path forward.
www.science.org
December 12, 2024 at 7:41 PM
Gearing up vs the potential of building "mirror life"
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
A looming danger of bioengineered reversed-chirality bacteria and microbes.
www.science.org/doi/10.1126/... @science.org
Cool synthetic biology papers, April edition 🧵
April 1, 2024 at 1:23 PM
Cool synthetic biology papers, April edition 🧵
2024 kicked off with lots of great synthetic biology papers. From January:
February 1, 2024 at 10:48 AM
2024 kicked off with lots of great synthetic biology papers. From January:
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
Continuous evolution in E. coli with an orthogonal replicon (like OrthoRep in yeast). Solves a long-standing gap in the E. coli directed evolution toolkit!
www.science.org/doi/10.1126/...
Continuous evolution in E. coli with an orthogonal replicon (like OrthoRep in yeast). Solves a long-standing gap in the E. coli directed evolution toolkit!
www.science.org/doi/10.1126/...
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
An Escherichia coli orthogonal replication system (EcORep) allows massively accelerated continuous evolution of introduced DNA in bacterial cells.
www.science.org
January 26, 2024 at 10:41 AM
Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli
Continuous evolution in E. coli with an orthogonal replicon (like OrthoRep in yeast). Solves a long-standing gap in the E. coli directed evolution toolkit!
www.science.org/doi/10.1126/...
Continuous evolution in E. coli with an orthogonal replicon (like OrthoRep in yeast). Solves a long-standing gap in the E. coli directed evolution toolkit!
www.science.org/doi/10.1126/...
A bumpy road ahead for genetic biocontainment
Excellent commentary in Nature Comms on some of the real-world challenges:
(1) robust testing
(2) open systems
(3) industry adoption
(4) considerations beyond human & environmental health
www.nature.com/articles/s41...
Excellent commentary in Nature Comms on some of the real-world challenges:
(1) robust testing
(2) open systems
(3) industry adoption
(4) considerations beyond human & environmental health
www.nature.com/articles/s41...
A bumpy road ahead for genetic biocontainment - Nature Communications
While the research community continues to develop novel proposals for intrinsic biocontainment of genetically engineered organisms, translation to real-world deployment faces several challenges.
www.nature.com
January 22, 2024 at 1:45 PM
A bumpy road ahead for genetic biocontainment
Excellent commentary in Nature Comms on some of the real-world challenges:
(1) robust testing
(2) open systems
(3) industry adoption
(4) considerations beyond human & environmental health
www.nature.com/articles/s41...
Excellent commentary in Nature Comms on some of the real-world challenges:
(1) robust testing
(2) open systems
(3) industry adoption
(4) considerations beyond human & environmental health
www.nature.com/articles/s41...