Samira Asgari
@samiraasgari.bsky.social
There is a crack in everything, that’s how the light gets in.
Scientist, Computational biologist. Asst. Prof. Icahn School of Medicine at Mount Sinai 🧬. Alum. Harvard Medical School 🇺🇸, EPFL🇨🇭, University of Tehran 🇮🇷
Scientist, Computational biologist. Asst. Prof. Icahn School of Medicine at Mount Sinai 🧬. Alum. Harvard Medical School 🇺🇸, EPFL🇨🇭, University of Tehran 🇮🇷
Pinned
Samira Asgari
@samiraasgari.bsky.social
· Aug 12
Lab news 🎉 We’ve received a 5-year, $2.3M award from NIH/NIGMS to leverage large-scale biobanks and build a data-driven approach to understanding sepsis biology and risk.
🎉 Grateful to have received one of the inaugural pilot awards from Mout Sinai Institute for Liver Research.
With this award, Dr. Michael Murray and my team will explore the role of somatic mutations in inflammatory liver diseases.
reports.mountsinai.org/article/live...
@sinaigenhealth.bsky.social
With this award, Dr. Michael Murray and my team will explore the role of somatic mutations in inflammatory liver diseases.
reports.mountsinai.org/article/live...
@sinaigenhealth.bsky.social
A New Hub for Liver Research Tackles Its First Investigations
Read about the work of Mount Sinai's new Institute for Liver Research
reports.mountsinai.org
October 24, 2025 at 3:05 PM
🎉 Grateful to have received one of the inaugural pilot awards from Mout Sinai Institute for Liver Research.
With this award, Dr. Michael Murray and my team will explore the role of somatic mutations in inflammatory liver diseases.
reports.mountsinai.org/article/live...
@sinaigenhealth.bsky.social
With this award, Dr. Michael Murray and my team will explore the role of somatic mutations in inflammatory liver diseases.
reports.mountsinai.org/article/live...
@sinaigenhealth.bsky.social
My lab is at #ashg2025 🧬🥳:
1- Platform talk & predoc finalist by Abhijith Biji: human genomics of infectious diseases
2- Lighting talk & poster by Ashley Richardson: somatic mutations underlying auto-inflammatory diseases
Looking forward to a few days of science & networking.
1- Platform talk & predoc finalist by Abhijith Biji: human genomics of infectious diseases
2- Lighting talk & poster by Ashley Richardson: somatic mutations underlying auto-inflammatory diseases
Looking forward to a few days of science & networking.
October 14, 2025 at 1:45 PM
My lab is at #ashg2025 🧬🥳:
1- Platform talk & predoc finalist by Abhijith Biji: human genomics of infectious diseases
2- Lighting talk & poster by Ashley Richardson: somatic mutations underlying auto-inflammatory diseases
Looking forward to a few days of science & networking.
1- Platform talk & predoc finalist by Abhijith Biji: human genomics of infectious diseases
2- Lighting talk & poster by Ashley Richardson: somatic mutations underlying auto-inflammatory diseases
Looking forward to a few days of science & networking.
Preprint alert 📜: How do social, behavioral, and environmental factors combine with genetics to shape risk for common diseases?
In our new work, led by senior bioinformatician Jane Brown, we sought to answer this question.
www.medrxiv.org/content/10.1...
In our new work, led by senior bioinformatician Jane Brown, we sought to answer this question.
www.medrxiv.org/content/10.1...
A Scalable Framework to Integrate Social Determinants of Health into Disease Risk Models using Biobank Survey Data
Complex diseases are a major global health burden, yet our ability to predict who is at risk remains limited. Risk is shaped by both heritable factors and non-genetic environmental, behavioral, and so...
www.medrxiv.org
October 2, 2025 at 3:50 PM
Preprint alert 📜: How do social, behavioral, and environmental factors combine with genetics to shape risk for common diseases?
In our new work, led by senior bioinformatician Jane Brown, we sought to answer this question.
www.medrxiv.org/content/10.1...
In our new work, led by senior bioinformatician Jane Brown, we sought to answer this question.
www.medrxiv.org/content/10.1...
If you are @cellpress.bsky.social #CSPrecisionGen25 conference don’t miss the talk by my brilliant PhD student Abhijith Biji. He will share our latest findings on human genomics study of 99 infectious disease phenotypes in ~800k individuals.
September 18, 2025 at 2:33 PM
If you are @cellpress.bsky.social #CSPrecisionGen25 conference don’t miss the talk by my brilliant PhD student Abhijith Biji. He will share our latest findings on human genomics study of 99 infectious disease phenotypes in ~800k individuals.
Preprint alert📜: How do lifetime viral exposures shape our immune system response to future infections? 🦠🧬
We explore this question in our new preprint, led by postdoc
Chad Hogan.
biorxiv.org/content/10.1...
#SystemsImmunology #Immunology #Virology #Infection #HostResponse
We explore this question in our new preprint, led by postdoc
Chad Hogan.
biorxiv.org/content/10.1...
#SystemsImmunology #Immunology #Virology #Infection #HostResponse
September 17, 2025 at 2:48 PM
Preprint alert📜: How do lifetime viral exposures shape our immune system response to future infections? 🦠🧬
We explore this question in our new preprint, led by postdoc
Chad Hogan.
biorxiv.org/content/10.1...
#SystemsImmunology #Immunology #Virology #Infection #HostResponse
We explore this question in our new preprint, led by postdoc
Chad Hogan.
biorxiv.org/content/10.1...
#SystemsImmunology #Immunology #Virology #Infection #HostResponse
Another two weeks, another MindShift issue; this one packed with updates on advancing clinical trials and new opportunities for psychedelics beyond the Global North.
Former NFL players turn to psilocybin & ayahuasca to heal concussion damage. Does the science back it up?
Discover this story and all the latest updates on psychedelics legalization, markets, and research in our newest issue.
#psychedelics #mentalhealth #neuroplasticity
mindshift.news/p/mindshift
Discover this story and all the latest updates on psychedelics legalization, markets, and research in our newest issue.
#psychedelics #mentalhealth #neuroplasticity
mindshift.news/p/mindshift
MindShift
Learn how a single dose of LSD provided lasting relief for patients with generalized anxiety disorder, why NFL athletes are turning to ayahuasca, and how a Trump-supporting billionaire took control of...
mindshift.news
September 11, 2025 at 1:39 PM
Another two weeks, another MindShift issue; this one packed with updates on advancing clinical trials and new opportunities for psychedelics beyond the Global North.
Starting the academic year with a trip to Yale. Looking forward to sharing how large biobanks and real-world data are reshaping our understanding of infectious disease genomics, and to the conversations ahead!
September 2, 2025 at 11:21 AM
Starting the academic year with a trip to Yale. Looking forward to sharing how large biobanks and real-world data are reshaping our understanding of infectious disease genomics, and to the conversations ahead!
Reposted by Samira Asgari
Congrats to @ashleyrichardson.bsky.social from the lab of @samiraasgari.bsky.social for being selected to give a lightning talk and poster presentation at #ASHG2025 on her work exploring the role of somatic mutations in Biobank-scale data as a cause of inborn errors of immunity!
#GenomicHealth
#GenomicHealth
August 27, 2025 at 7:14 PM
Congrats to @ashleyrichardson.bsky.social from the lab of @samiraasgari.bsky.social for being selected to give a lightning talk and poster presentation at #ASHG2025 on her work exploring the role of somatic mutations in Biobank-scale data as a cause of inborn errors of immunity!
#GenomicHealth
#GenomicHealth
🤩What a nice surprise to see @mindshiftnews.bsky.social mentioned by @jeanabbiateci.bsky.social, seasoned journalist and founder of the award-winning newsletter bulletin.fr.
Curious? Read our latest issue: bit.ly/4oCg22F
Want to support us? Subscribe (free, ad-free): mindshift.news/subscribe
Curious? Read our latest issue: bit.ly/4oCg22F
Want to support us? Subscribe (free, ad-free): mindshift.news/subscribe
August 16, 2025 at 6:26 PM
🤩What a nice surprise to see @mindshiftnews.bsky.social mentioned by @jeanabbiateci.bsky.social, seasoned journalist and founder of the award-winning newsletter bulletin.fr.
Curious? Read our latest issue: bit.ly/4oCg22F
Want to support us? Subscribe (free, ad-free): mindshift.news/subscribe
Curious? Read our latest issue: bit.ly/4oCg22F
Want to support us? Subscribe (free, ad-free): mindshift.news/subscribe
Lab news 🎉 We’ve received a 5-year, $2.3M award from NIH/NIGMS to leverage large-scale biobanks and build a data-driven approach to understanding sepsis biology and risk.
August 12, 2025 at 6:35 PM
Lab news 🎉 We’ve received a 5-year, $2.3M award from NIH/NIGMS to leverage large-scale biobanks and build a data-driven approach to understanding sepsis biology and risk.
I just learned that Americans call some chalky, non-chocolatey!, pale candies ‘Smarties’ 😱 and they have no idea what they’re missing. Europeans, you know what I mean.
July 3, 2025 at 7:32 PM
I just learned that Americans call some chalky, non-chocolatey!, pale candies ‘Smarties’ 😱 and they have no idea what they’re missing. Europeans, you know what I mean.
Back in Boston for #FOGBoston and excited to share our latest work! Using #Genomics, clinical data, and #RealWorldEvidence from three large #Biobanks, we identified hundreds of novel genetic risk loci for #InfectiousDiseases. If you're around or want to chat, let’s connect!
June 23, 2025 at 3:55 PM
Back in Boston for #FOGBoston and excited to share our latest work! Using #Genomics, clinical data, and #RealWorldEvidence from three large #Biobanks, we identified hundreds of novel genetic risk loci for #InfectiousDiseases. If you're around or want to chat, let’s connect!
Reposted by Samira Asgari
📢 Just posted: Our preprint introducing SPC — Spectral Components — is now live on medRxiv!
Led by Dr. Ruhollah Shemirani and years in the making, this method offers a robust, scalable way to adjust for recent population structure in genomic analyses.
🔗 www.medrxiv.org/content/10.1...
1/9
Led by Dr. Ruhollah Shemirani and years in the making, this method offers a robust, scalable way to adjust for recent population structure in genomic analyses.
🔗 www.medrxiv.org/content/10.1...
1/9
SPC: a SPectral Component approach to address recent population structure in genomic analysis
Population structure is a well-known confounder in statistical genetics, particularly in genome-wide association studies (GWAS), where it can lead to inflated test statistics and spurious associations...
www.medrxiv.org
June 17, 2025 at 4:26 PM
📢 Just posted: Our preprint introducing SPC — Spectral Components — is now live on medRxiv!
Led by Dr. Ruhollah Shemirani and years in the making, this method offers a robust, scalable way to adjust for recent population structure in genomic analyses.
🔗 www.medrxiv.org/content/10.1...
1/9
Led by Dr. Ruhollah Shemirani and years in the making, this method offers a robust, scalable way to adjust for recent population structure in genomic analyses.
🔗 www.medrxiv.org/content/10.1...
1/9
Excited to be in beautiful Madison, visiting colleagues @uwmadison.bsky.social! I’ll be sharing our recent work using three large-scale biobanks to advance understanding of the human genomics of infectious diseases. Looking forward to a full day of science and fun!
June 2, 2025 at 1:12 PM
Excited to be in beautiful Madison, visiting colleagues @uwmadison.bsky.social! I’ll be sharing our recent work using three large-scale biobanks to advance understanding of the human genomics of infectious diseases. Looking forward to a full day of science and fun!
I asked #ChatGPT: Based on my prompts so far, describe me in 20 words.
The answer: Data-driven, sharp-tongued scientist blending genomics, AI, and storytelling. Strategic thinker, clear writer, playful observer—always chasing impact, never fluff.
I think we're in a relationship.
The answer: Data-driven, sharp-tongued scientist blending genomics, AI, and storytelling. Strategic thinker, clear writer, playful observer—always chasing impact, never fluff.
I think we're in a relationship.
April 11, 2025 at 7:21 PM
I asked #ChatGPT: Based on my prompts so far, describe me in 20 words.
The answer: Data-driven, sharp-tongued scientist blending genomics, AI, and storytelling. Strategic thinker, clear writer, playful observer—always chasing impact, never fluff.
I think we're in a relationship.
The answer: Data-driven, sharp-tongued scientist blending genomics, AI, and storytelling. Strategic thinker, clear writer, playful observer—always chasing impact, never fluff.
I think we're in a relationship.
To women who lead, inspire, mentor, break barriers, and lift others as they rise - thank you for shaping the future! 🥂💜
#WomenMentors #IWD #InternationalWomensDay
Many thanks to @NaturePortfolio for giving us an opportunity to acknowledge some of the women who inspire us.
#WomenMentors #IWD #InternationalWomensDay
Many thanks to @NaturePortfolio for giving us an opportunity to acknowledge some of the women who inspire us.
Six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others
#IWD #InternationalWomensDay
https://go.nature.com/43w9Voe
#IWD #InternationalWomensDay
https://go.nature.com/43w9Voe
Behind every great woman in science, there’s another great woman in science
Nature - To mark International Women’s Day on 8 March, six award-winning female scientists highlight women who have inspired them by pushing innovative research and creating opportunities for others.
go.nature.com
March 8, 2025 at 6:35 PM
To women who lead, inspire, mentor, break barriers, and lift others as they rise - thank you for shaping the future! 🥂💜
#WomenMentors #IWD #InternationalWomensDay
Many thanks to @NaturePortfolio for giving us an opportunity to acknowledge some of the women who inspire us.
#WomenMentors #IWD #InternationalWomensDay
Many thanks to @NaturePortfolio for giving us an opportunity to acknowledge some of the women who inspire us.
UES cafe - #NYC
guy 1: …these girls serve some of the wealthiest women in New York. They can’t be, you know, ugly.
g2: That’s why I had to let [name] go. She was not bad looking, but kind of bland…poker face.
g1: What about [name]?
g2: She was 38.
#peopleunfiltered 🤢
guy 1: …these girls serve some of the wealthiest women in New York. They can’t be, you know, ugly.
g2: That’s why I had to let [name] go. She was not bad looking, but kind of bland…poker face.
g1: What about [name]?
g2: She was 38.
#peopleunfiltered 🤢
February 26, 2025 at 4:29 PM
UES cafe - #NYC
guy 1: …these girls serve some of the wealthiest women in New York. They can’t be, you know, ugly.
g2: That’s why I had to let [name] go. She was not bad looking, but kind of bland…poker face.
g1: What about [name]?
g2: She was 38.
#peopleunfiltered 🤢
guy 1: …these girls serve some of the wealthiest women in New York. They can’t be, you know, ugly.
g2: That’s why I had to let [name] go. She was not bad looking, but kind of bland…poker face.
g1: What about [name]?
g2: She was 38.
#peopleunfiltered 🤢
In snow-filled Breckenridge for the inaugural Keystone somatic mutation meeting! We are new to this space, so I’m beyond grateful for receiving the Keystone Symposia fellowship—giving us the chance to share our work & learn from some of the field's best. Excited for what's ahead!
February 18, 2025 at 4:04 PM
In snow-filled Breckenridge for the inaugural Keystone somatic mutation meeting! We are new to this space, so I’m beyond grateful for receiving the Keystone Symposia fellowship—giving us the chance to share our work & learn from some of the field's best. Excited for what's ahead!
Looking forward to spending the afternoon with our midtown neighbors. Stop by if you are on campus (talk starts at 4:30).
February 6, 2025 at 5:20 PM
Looking forward to spending the afternoon with our midtown neighbors. Stop by if you are on campus (talk starts at 4:30).
Reposted by Samira Asgari
#MLCB2025 will be Sept 10-11 at @nygenome.org in NYC! Paper deadline June 1st & in-person registration will open in May. Please sign up for our mailing list groups.google.com/g/mlcb/ for future announcements. More details at mlcb.github.io. Please RP!
January 27, 2025 at 6:40 PM
#MLCB2025 will be Sept 10-11 at @nygenome.org in NYC! Paper deadline June 1st & in-person registration will open in May. Please sign up for our mailing list groups.google.com/g/mlcb/ for future announcements. More details at mlcb.github.io. Please RP!
Artists often have rituals that accompany their creative pursuits. It’s less spoken of among scientists, yet I know many who have their own. For me, writing projects begin with an obsessive search for the song to embody its essence (Jacques Brel sets the tone atm!). What fuels your process?
January 28, 2025 at 2:42 PM
Artists often have rituals that accompany their creative pursuits. It’s less spoken of among scientists, yet I know many who have their own. For me, writing projects begin with an obsessive search for the song to embody its essence (Jacques Brel sets the tone atm!). What fuels your process?
It would be funny if it couldn’t be true.
January 24, 2025 at 7:47 PM
It would be funny if it couldn’t be true.
Reposted by Samira Asgari
If you’ve been directly impacted by a pause or cancellation of an NIH study session, we @forbes.com would like to talk to you
All NIH study sections canceled indefinitely. This will halt science and devastate research budgets in universities.
January 22, 2025 at 10:59 PM
If you’ve been directly impacted by a pause or cancellation of an NIH study session, we @forbes.com would like to talk to you
And the cherry on the cake… @ashleyrichardson.bsky.social got the prize for the best lighting talk!
#proudPI
#proudPI
January 16, 2025 at 3:25 PM
And the cherry on the cake… @ashleyrichardson.bsky.social got the prize for the best lighting talk!
#proudPI
#proudPI