Ryan Ly
@ryanly.bsky.social
Neuroscience research software engineer. Technical lead of the NWB data standard and software for neurophysiology. Passionate about building open source software and infrastructure. https://github.com/rly
He/him
He/him
Reposted by Ryan Ly
🧠 Introducing NeuroDiscoveryBench. Built with @alleninstitute.org, it’s the first benchmark for evaluating AI systems like our Asta DataVoyager agent on neuroscience data. The benchmark tests whether AI can truly extract insights from complex brain datasets.
December 12, 2025 at 8:41 PM
🧠 Introducing NeuroDiscoveryBench. Built with @alleninstitute.org, it’s the first benchmark for evaluating AI systems like our Asta DataVoyager agent on neuroscience data. The benchmark tests whether AI can truly extract insights from complex brain datasets.
Our paper was born from insights gained during the first Open Data in Neurophysiology symposium (ODIN 2023). If you’re interested in the future of open neuroscience, look out for the next edition in 2027!
November 26, 2025 at 10:42 PM
Our paper was born from insights gained during the first Open Data in Neurophysiology symposium (ODIN 2023). If you’re interested in the future of open neuroscience, look out for the next edition in 2027!
At the same time, institutions can implement funding frameworks that prioritize open science initiatives and recognize contributions to open neuroscience in career evaluations.
November 26, 2025 at 10:42 PM
At the same time, institutions can implement funding frameworks that prioritize open science initiatives and recognize contributions to open neuroscience in career evaluations.
To effectively advance open neuroscience, we need both active engagement from individual researchers and supportive institutional structures. Researchers can drive change through sharing tools and datasets, fostering collaboration, and building an open science community.
November 26, 2025 at 10:42 PM
To effectively advance open neuroscience, we need both active engagement from individual researchers and supportive institutional structures. Researchers can drive change through sharing tools and datasets, fostering collaboration, and building an open science community.
Establishing and maintaining robust data infrastructure and standardized data formats are crucial for effective data sharing in neurophysiology. Initiatives like @nwb.org and @dandiarchive.org are working to make data more accessible and usable for researchers in the field.
November 26, 2025 at 10:42 PM
Establishing and maintaining robust data infrastructure and standardized data formats are crucial for effective data sharing in neurophysiology. Initiatives like @nwb.org and @dandiarchive.org are working to make data more accessible and usable for researchers in the field.
While the advantages of open neuroscience are clear, challenges remain, especially concerning data heterogeneity and limited resources. Our paper discusses practical strategies to overcome these obstacles and facilitate better collaboration and data sharing among researchers.
November 26, 2025 at 10:42 PM
While the advantages of open neuroscience are clear, challenges remain, especially concerning data heterogeneity and limited resources. Our paper discusses practical strategies to overcome these obstacles and facilitate better collaboration and data sharing among researchers.
Open science has revolutionized fields like structural biology and genomics, allowing for rapid advancements. We argue that by embracing open data and collaboration in neuroscience, we can gain transformative insights that can help us understand the brain better than before.
November 26, 2025 at 10:42 PM
Open science has revolutionized fields like structural biology and genomics, allowing for rapid advancements. We argue that by embracing open data and collaboration in neuroscience, we can gain transformative insights that can help us understand the brain better than before.
Check out our new perspective paper in eNeuro! We explore recent advancements and future prospects in open neuroscience, and discuss how open science practices, data sharing, and structural changes can create a more collaborative and transparent scientific ecosystem
www.eneuro.org/content/12/1...
www.eneuro.org/content/12/1...
Open Data In Neurophysiology: Advancements, Solutions & Challenges
Ongoing efforts over the last 50 years have made data and methods more reproducible and transparent across the life sciences. This openness has led to transformative insights and vastly accelerated sc...
www.eneuro.org
November 26, 2025 at 10:42 PM
Check out our new perspective paper in eNeuro! We explore recent advancements and future prospects in open neuroscience, and discuss how open science practices, data sharing, and structural changes can create a more collaborative and transparent scientific ecosystem
www.eneuro.org/content/12/1...
www.eneuro.org/content/12/1...
Reposted by Ryan Ly
At #SfN25? Catch @ryanly.bsky.social at the NWB/DANDI booth #3835 at 10am today for a demo of NWB GUIDE, our app for converting data from 40 common neurophysiology and behavior data formats to NWB without writing any code!
nwb-guide.readthedocs.io
@nwb.org @dandiarchive.org
nwb-guide.readthedocs.io
@nwb.org @dandiarchive.org
November 18, 2025 at 4:19 PM
At #SfN25? Catch @ryanly.bsky.social at the NWB/DANDI booth #3835 at 10am today for a demo of NWB GUIDE, our app for converting data from 40 common neurophysiology and behavior data formats to NWB without writing any code!
nwb-guide.readthedocs.io
@nwb.org @dandiarchive.org
nwb-guide.readthedocs.io
@nwb.org @dandiarchive.org
Reposted by Ryan Ly
Miss out on the @nwb.org poster at #SfN25? Never fear - you can still catch up with the team at learn more about nwb.org at the DANDI booth #3831! #OpenScience #OpenData
November 17, 2025 at 8:23 PM
Miss out on the @nwb.org poster at #SfN25? Never fear - you can still catch up with the team at learn more about nwb.org at the DANDI booth #3831! #OpenScience #OpenData
Happening in 10 minutes!
Catch me at the DANDI/NWB booth (3831) today at 1 pm for a live demo of this online textbook I developed with a former student of mine!
#SfN25 #SfN2025 @sfn.org
(Or check it out for yourself 👉 nwb4edu.github.io )
#SfN25 #SfN2025 @sfn.org
(Or check it out for yourself 👉 nwb4edu.github.io )
November 16, 2025 at 8:49 PM
Happening in 10 minutes!
Come say hi at the @nwb.org and @dandiarchive.org booth #3831 at SfN! Learn about how the standard and archive can help advance your science and fulfill your data sharing requirements! We're also ready to help you convert your data to NWB and publish it to DANDI 📶🎉
Looking forward to seeing everyone at SfN this week! Stop by our booth (#3831) to learn about NWB and the @dandiarchive.org , check out our posters on multi-modal open data ecosystems and AI coding agents, or catch one of our showcase talks throughout the conference.
#SfN2025
Full schedule:
#SfN2025
Full schedule:
November 16, 2025 at 4:59 PM
Come say hi at the @nwb.org and @dandiarchive.org booth #3831 at SfN! Learn about how the standard and archive can help advance your science and fulfill your data sharing requirements! We're also ready to help you convert your data to NWB and publish it to DANDI 📶🎉
Reposted by Ryan Ly
1/
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
September 17, 2025 at 7:33 PM
1/
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
Reposted by Ryan Ly
🎉 Deadline is *tomorrow*!
Join the @flatironinstitute.org workshop on pynapple & NeMos @sfn.org this November to analyze and model neural data
pynapple: analyze neural time series
NeMoS: model neural population dynamics
Meals + accommodation included
👉 neurorse.flatironinstitute.org/events/2025/...
Join the @flatironinstitute.org workshop on pynapple & NeMos @sfn.org this November to analyze and model neural data
pynapple: analyze neural time series
NeMoS: model neural population dynamics
Meals + accommodation included
👉 neurorse.flatironinstitute.org/events/2025/...
SfN 2025
neurorse.flatironinstitute.org
September 11, 2025 at 5:47 PM
🎉 Deadline is *tomorrow*!
Join the @flatironinstitute.org workshop on pynapple & NeMos @sfn.org this November to analyze and model neural data
pynapple: analyze neural time series
NeMoS: model neural population dynamics
Meals + accommodation included
👉 neurorse.flatironinstitute.org/events/2025/...
Join the @flatironinstitute.org workshop on pynapple & NeMos @sfn.org this November to analyze and model neural data
pynapple: analyze neural time series
NeMoS: model neural population dynamics
Meals + accommodation included
👉 neurorse.flatironinstitute.org/events/2025/...
Reposted by Ryan Ly
NWB just turned 10 years old! Researchers worldwide have downloaded 1.9 PB of NWB data from @dandiarchive.org. This animation shows the reach of NWB, facilitating collaboration across the globe. What impact has open neurophysiology data had on your science? Share your stories! 🧠
@openscience
@openscience
August 18, 2025 at 1:57 PM
NWB just turned 10 years old! Researchers worldwide have downloaded 1.9 PB of NWB data from @dandiarchive.org. This animation shows the reach of NWB, facilitating collaboration across the globe. What impact has open neurophysiology data had on your science? Share your stories! 🧠
@openscience
@openscience
Reposted by Ryan Ly
I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...
I’m an award-winning mathematician. Trump just cut my funding.
The “Mozart of Math” tried to stay out of politics. Then it came for his research.
newsletter.ofthebrave.org
August 18, 2025 at 3:45 PM
I wrote an op-ed on the world-class STEM research ecosystem in the United States, and how this ecosystem is now under attack on multiple fronts by the current administration: newsletter.ofthebrave.org/p/im-an-awar...
Reposted by Ryan Ly
This has been a blast! Such a treat to be hosted by @hhmijanelia.bsky.social at this workshop by organized by @nwb.org! Re-analysis of open-data form @dandiarchive.org with so many talented scientists has been so much fun!
July 20, 2025 at 10:07 AM
This has been a blast! Such a treat to be hosted by @hhmijanelia.bsky.social at this workshop by organized by @nwb.org! Re-analysis of open-data form @dandiarchive.org with so many talented scientists has been so much fun!
Reposted by Ryan Ly
🎉 Congrats to all the organizers on another great workshop! The @nwb.org community appreciates all you do. ❤️
@bendichter.com @ryanly.bsky.social @stephmprince.bsky.social
@bendichter.com @ryanly.bsky.social @stephmprince.bsky.social
Congrats on another successful #NeuroDataReHack!
Inspiring to see the creativity & collaboration around open neurophys data. Attendees are invited to apply for the Kavli NeuroData Discovery Award - a one-year grant supporting innovative #DataReuse.
Excited to see your ideas! #KavliNeuro #OpenData
Inspiring to see the creativity & collaboration around open neurophys data. Attendees are invited to apply for the Kavli NeuroData Discovery Award - a one-year grant supporting innovative #DataReuse.
Excited to see your ideas! #KavliNeuro #OpenData
NeuroDataReHack participants from all over the world are finishing up 10 exciting projects analyzing open neurophys data on @dandiarchive.org. Thank you @hhmijanelia.bsky.social for being amazing hosts as always! Stay tuned for the workshop report.
@chrishalcrow.bsky.social @mcelotto95.bsky.social
@chrishalcrow.bsky.social @mcelotto95.bsky.social
July 18, 2025 at 8:21 PM
🎉 Congrats to all the organizers on another great workshop! The @nwb.org community appreciates all you do. ❤️
@bendichter.com @ryanly.bsky.social @stephmprince.bsky.social
@bendichter.com @ryanly.bsky.social @stephmprince.bsky.social
Reposted by Ryan Ly
NeuroDataReHack participants from all over the world are finishing up 10 exciting projects analyzing open neurophys data on @dandiarchive.org. Thank you @hhmijanelia.bsky.social for being amazing hosts as always! Stay tuned for the workshop report.
@chrishalcrow.bsky.social @mcelotto95.bsky.social
@chrishalcrow.bsky.social @mcelotto95.bsky.social
July 18, 2025 at 5:34 PM
NeuroDataReHack participants from all over the world are finishing up 10 exciting projects analyzing open neurophys data on @dandiarchive.org. Thank you @hhmijanelia.bsky.social for being amazing hosts as always! Stay tuned for the workshop report.
@chrishalcrow.bsky.social @mcelotto95.bsky.social
@chrishalcrow.bsky.social @mcelotto95.bsky.social
Reposted by Ryan Ly
For 80 years, the United States led the world in science and engineering.
We could lose that position in a single year.
www.science.org/content/arti...
We could lose that position in a single year.
www.science.org/content/arti...
‘It’s a nightmare.’ U.S. funding cuts threaten academic science jobs at all levels
“There is a lot of pressure to essentially leave the country or not pursue research,” one Ph.D. student says
www.science.org
July 9, 2025 at 4:00 AM
For 80 years, the United States led the world in science and engineering.
We could lose that position in a single year.
www.science.org/content/arti...
We could lose that position in a single year.
www.science.org/content/arti...
Reposted by Ryan Ly
My first piece with @thetransmitter.bsky.social is out! Open data is transforming neuroscience—350+ datasets on
@dandiarchive.org in @nwb.org, new tools like Neurosift enabling discovery and analysis, and researchers all over the world discovering new insights using open data as a key resource!
@dandiarchive.org in @nwb.org, new tools like Neurosift enabling discovery and analysis, and researchers all over the world discovering new insights using open data as a key resource!
Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com
#neuroskyence
www.thetransmitter.org/open-neurosc...
#neuroskyence
www.thetransmitter.org/open-neurosc...
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments.
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new…
www.thetransmitter.org
July 7, 2025 at 7:58 PM
My first piece with @thetransmitter.bsky.social is out! Open data is transforming neuroscience—350+ datasets on
@dandiarchive.org in @nwb.org, new tools like Neurosift enabling discovery and analysis, and researchers all over the world discovering new insights using open data as a key resource!
@dandiarchive.org in @nwb.org, new tools like Neurosift enabling discovery and analysis, and researchers all over the world discovering new insights using open data as a key resource!
Reposted by Ryan Ly
#FlatironCCN is hosting a @nwb.org hackathon in August to bring together scientists, research software engineers and students to work on development, tool integration, outreach and training. Learn more and register: nwb.org/events/hck25... #neuroscience #science
June 17, 2025 at 3:28 PM
#FlatironCCN is hosting a @nwb.org hackathon in August to bring together scientists, research software engineers and students to work on development, tool integration, outreach and training. Learn more and register: nwb.org/events/hck25... #neuroscience #science
Reposted by Ryan Ly
I would love (and am trying) to build a whole lab off of data reuse + modeling. This article pointed to some useful resources I hadn't heard of.
I would also add that reuse can be for things far afield from what the data was originally collected for. Your data may have value you've never dreamt of!
I would also add that reuse can be for things far afield from what the data was originally collected for. Your data may have value you've never dreamt of!
Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com
#neuroskyence
www.thetransmitter.org/open-neurosc...
#neuroskyence
www.thetransmitter.org/open-neurosc...
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments.
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new…
www.thetransmitter.org
July 7, 2025 at 1:59 PM
I would love (and am trying) to build a whole lab off of data reuse + modeling. This article pointed to some useful resources I hadn't heard of.
I would also add that reuse can be for things far afield from what the data was originally collected for. Your data may have value you've never dreamt of!
I would also add that reuse can be for things far afield from what the data was originally collected for. Your data may have value you've never dreamt of!
Reposted by Ryan Ly
Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com
#neuroskyence
www.thetransmitter.org/open-neurosc...
#neuroskyence
www.thetransmitter.org/open-neurosc...
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments.
Data reuse represents an opportunity to accelerate the pace of science, reduce costs and increase the value of our collective research investments. New tools that make open data easier to use—and new…
www.thetransmitter.org
July 7, 2025 at 1:47 PM
Data reuse represents an opportunity to accelerate science, reduce costs and increase the value of investments. But to date, the field hasn't placed equal emphasis on the reuse side of the data-sharing equation, writes @bendichter.com
#neuroskyence
www.thetransmitter.org/open-neurosc...
#neuroskyence
www.thetransmitter.org/open-neurosc...
Reposted by Ryan Ly
Join us at the NWB Community Hackathon at @flatironinstitute.org, Aug 4-6! Hack on NWB-related projects with the devs and tool builders, integrate tools with NWB, contribute to the standard, and help shape the future of neurophysiology data standardization. nwb.org/events/hck25...
NWB Community Hackathon at Flatiron Institute -Neurodata Without Borders
nwb.org
June 11, 2025 at 7:01 PM
Join us at the NWB Community Hackathon at @flatironinstitute.org, Aug 4-6! Hack on NWB-related projects with the devs and tool builders, integrate tools with NWB, contribute to the standard, and help shape the future of neurophysiology data standardization. nwb.org/events/hck25...