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Flatiron Institute
@flatironinstitute.org
Advancing scientific research through computational methods and software tools. Centers: #FlatironCCA, #FlatironCCB, #FlatironCCM, #FlatironCCN and #FlatironCCQ
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While most AI models are trained on text and images, a multidisciplinary team of scientists has something different in mind: #AI trained on physics. https://www.simonsfoundation.org/these-new-ai-models-are-trained-on-physics-not-words-and-theyre-driving-discovery/ @polymathicai.bsky.social #science
These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery
These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery on Simons Foundation
www.simonsfoundation.org
December 24, 2025 at 4:28 PM
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In 2025, our researchers pushed science into new territory through bold inquiry & transformative science. Look back at our biggest stories this year, highlighting the people and ideas reshaping our understanding of the universe — and of ourselves: simonsfoundation.org/from-ringing... #science #math
From Ringing Black Holes to Restoring Gut Health: Science at Simons in 2025
From Ringing Black Holes to Restoring Gut Health: Science at Simons in 2025 on Simons Foundation
simonsfoundation.org
December 23, 2025 at 6:50 PM
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JWST found mysterious "Little Red Dots" in the early Universe, but what are they? Our new paper points to Quasi-Stars: supermassive black hole seeds hidden inside giant, *pulsating* envelopes! arxiv.org/abs/2512.17997
December 23, 2025 at 4:31 AM
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New paper! In work led by Matteo Cantiello @flatironinstitute.org we predict an instability strip for quasi-stars, which we argue is consistent with the observed variability properties of JWST’s Little Red Dots.

arxiv.org/abs/2512.17997
December 23, 2025 at 3:07 PM
Deadline in 2 weeks: Our Canonical Cortical Computations workshop, which aims to develop a project to understand canonical cortical computations at the circuit level: https://www.simonsfoundation.org/simons-foundation-now-accepting-applications-for-workshop-on-canonical-cortical-computations/
Simons Foundation Now Accepting Applications for Workshop on Canonical Cortical Computations
Simons Foundation Now Accepting Applications for Workshop on Canonical Cortical Computations on Simons Foundation
www.simonsfoundation.org
December 22, 2025 at 9:07 AM
New AI models from @polymathicai.bsky.social use knowledge from scientific fields and apply it to others. Walrus (seen below) can tackle systems from exploding stars to Wi-Fi signals: https://www.simonsfoundation.org/these-new-ai-models-are-trained-on-physics-not-words-and-theyre-driving-discovery/
December 19, 2025 at 7:14 PM
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Just 3 days until Birth + Carnage comes alive! This collaboration between choreographer Marla Phelan and @flatironinstitute.org Blakesley Burkhart fuses dance with astrophysics to explore where cosmic forces meet human connection: https://www.lamama.org/birth-carnage #science #dance #astrophysics
Birth + Carnage - December 19-21
Birth + Carnage, a work by Marla Phelan, merges choreography and astrophysics– transforming computational simulations of stellar birth into visceral metaphor, digital landscape, and choreographic fram...
www.lamama.org
December 16, 2025 at 7:45 PM
Last month, our Accretion at the Disk-Halo Interface Workshop brought together simulators from #FlatironCCA and observers from around the country to figure out how gas accretes onto galaxies to fuel star formation. #science #astrophysics
December 18, 2025 at 5:23 PM
A new study from #FlatironCCB researchers uses cutting-edge computational modeling of the fruit fly gut to lay the groundwork for understanding how organs and tissues take shape across many species: https://www.simonsfoundation.org/from-ring-to-keyhole-modeling-how-tissues-mold-the-fruit-flys-gut/
From Ring to Keyhole: Modeling How Tissues Mold the Fruit Fly's Gut
A study on the fruit fly gut led by Flatiron Institute researchers gives insight into how tissues are shaped by bumping into their neighbors.
www.simonsfoundation.org
December 17, 2025 at 4:03 PM
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Interested in joining the Flatiron Institute for an extended visit? Applications for our Idea Scholar program are due in just under a month! Learn more and apply: https://www.simonsfoundation.org/flatiron/idea_scholar_program/ #science #math #computationalscience
Idea Scholar Program
The Flatiron Institute’s Idea Scholar program invites distinguished scientists for extended visits to develop scientific talent and foster collaboration.
www.simonsfoundation.org
December 16, 2025 at 2:04 PM
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Reposted by Flatiron Institute
New AI ‘foundational models' from @polymathicai.bsky.social are leveraging knowledge from scientific fields to address seemingly completely different problems in others: https://www.simonsfoundation.org/these-new-ai-models-are-trained-on-physics-not-words-and-theyre-driving-discovery/ #AI #science
December 12, 2025 at 4:13 PM
Applications are due in one month for our summer research internships! View full list of open positions: https://apply.interfolio.com/52828/positions #science
December 15, 2025 at 9:08 AM
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Humans have always looked to the moon, but there's so much left to discover. At our December Presents event, "Reflections on the Moon," @flatironinstitute.org's Adrian Bayer, sociologist Tracy Scott and NASA's Denise Hill explored what the moon still has left to teach us.
December 11, 2025 at 7:32 PM
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The Center for Computational Biology at the Flatiron Institute is accepting applications for summer intern positions. CCB is a great place to work, and the intern program is excellent. Please check out the Computer Vision and Developmental Dynamics groups in particular. apply.interfolio.com/177779
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December 11, 2025 at 3:29 PM
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The Simons Foundation is #hiring! Browse our open positions, including software engineer intern, events coordinator, and grants administrator: https://www.simonsfoundation.org/careers/ #science #math #jobs
December 10, 2025 at 7:47 PM
Members of the @polymathicai.bsky.social collaboration present two new #AI models trained using real scientific datasets to tackle problems in astronomy and fluidlike systems: https://www.simonsfoundation.org/these-new-ai-models-are-trained-on-physics-not-words-and-theyre-driving-discovery/
These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery
These New AI Models Are Trained on Physics, Not Words, and They’re Driving Discovery on Simons Foundation
www.simonsfoundation.org
December 9, 2025 at 9:26 PM
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Apps for our Fellows-to-Faculty Award are due in 1 month! This program supports talented early career scientists in #neuroscience & #autismresearch by facilitating their transition into tenure-track positions. Deadline is 1/14/26: https://www.simonsfoundation.org/grant/fellows-to-faculty-award/
Fellows-to-Faculty Award
The Fellows-to-Faculty Award is a new iteration of the previously offered Simons Foundation Independence Awards.
www.simonsfoundation.org
December 9, 2025 at 2:20 PM
Interested in a summer internship in computational bio, math, catalysis, quantum physics, or neuroscience? Check out our summer research positions: https://apply.interfolio.com/52828/positions #science
December 9, 2025 at 1:56 PM
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New simulations created by @flatironinstitute.org and Institute for Advanced Study astrophysicists reveal how material flowing around and into black holes creates intense light shows: https://www.simonsfoundation.org/2025/12/03/groundbreaking-simulations-show-how-black-holes-glow-bright/ #science
Groundbreaking Simulations Show How Black Holes Glow Bright
Research by astrophysicists at the Flatiron Institute and the Institute for Advanced Study reveals how material flowing around and into black holes creates intense light shows.
www.simonsfoundation.org
December 8, 2025 at 4:51 PM
#FlatironCCA scientists Ore Gottlieb, Brian Metzger, Maximiliano Isi, and colleagues solved the mystery of an 'impossible' merger between two massive black holes: https://www.simonsfoundation.org/2025/11/10/mysterious-impossible-merger-of-two-massive-black-holes-explained/ #science #astrophysics
Mysterious ‘Impossible’ Merger of Two Massive Black Holes Explained
Mysterious ‘Impossible’ Merger of Two Massive Black Holes Explained on Simons Foundation
www.simonsfoundation.org
December 8, 2025 at 4:52 PM
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Happy to share our cryoEM Ensemble Optimization method! 🎉It infers optimal structures and their weights directly from individual cryoEM images - no maps just physics! with David Sliva-Sánchez, @erikhthiede.bsky.social & Roy Lederman www.biorxiv.org/content/10.6...
Cryo-electron microscopy ensemble optimization using individual particles and physical constraints
Biomolecules are inherently dynamic, and understanding their conformational ensemble distributions is essential for understanding their dynamics and biological roles. Cryo-electron microscopy (cryo-EM...
www.biorxiv.org
December 5, 2025 at 4:13 PM