Ruben van Helden
@rvhelden.bsky.social
Sr. Scientist at Cardiac Organoid start-up HeartBeat.bio, former PhD Christine Mummery lab.
Cardiac organoid disease models | High-throughput screening | Pluripotent Stem Cells | Omics
Cardiac organoid disease models | High-throughput screening | Pluripotent Stem Cells | Omics
Reposted by Ruben van Helden
"academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it... The dominant four collectively generated... $12 billion in profits between 2019 and 2024."
November 18, 2025 at 6:48 AM
"academic publishing is dominated by profit-oriented, multinational companies for whom scientific knowledge is a commodity to be sold back to the academic community who created it... The dominant four collectively generated... $12 billion in profits between 2019 and 2024."
Reposted by Ruben van Helden
Whooooaaaa, this is extremely neat!
And spectropolarimetry (which is the best, and what we used in my first paper too!) is at its core 💙
In a nutshell: astronomers used the polarization of light to study the shape of a supernova explosion before it interacted with surrounding material.
🔭🧪
And spectropolarimetry (which is the best, and what we used in my first paper too!) is at its core 💙
In a nutshell: astronomers used the polarization of light to study the shape of a supernova explosion before it interacted with surrounding material.
🔭🧪
For the first time ever, astronomers have unveiled the shape of a supernova explosion just a day after detection, as the blast was breaking through the star’s surface.
Achieved by our VLT, this feat will help us understand how massive stars die: https://www.eso.org/public/news/eso2520/
🔭 🧪 ☄️
Achieved by our VLT, this feat will help us understand how massive stars die: https://www.eso.org/public/news/eso2520/
🔭 🧪 ☄️
November 12, 2025 at 10:26 PM
Whooooaaaa, this is extremely neat!
And spectropolarimetry (which is the best, and what we used in my first paper too!) is at its core 💙
In a nutshell: astronomers used the polarization of light to study the shape of a supernova explosion before it interacted with surrounding material.
🔭🧪
And spectropolarimetry (which is the best, and what we used in my first paper too!) is at its core 💙
In a nutshell: astronomers used the polarization of light to study the shape of a supernova explosion before it interacted with surrounding material.
🔭🧪
Reposted by Ruben van Helden
Reposted by Ruben van Helden
Available via #OpenAccess.
pubs.rsc.org/en/content/a...
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19
Huub J. Weener et al
@andriesvdm.bsky.social @rvhelden.bsky.social @middeldorps.bsky.social
pubs.rsc.org/en/content/a...
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19
Huub J. Weener et al
@andriesvdm.bsky.social @rvhelden.bsky.social @middeldorps.bsky.social
October 14, 2025 at 8:39 AM
Available via #OpenAccess.
pubs.rsc.org/en/content/a...
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19
Huub J. Weener et al
@andriesvdm.bsky.social @rvhelden.bsky.social @middeldorps.bsky.social
pubs.rsc.org/en/content/a...
Blood-perfused Vessels-on-Chips stimulated with patient plasma recapitulate endothelial activation and microthrombosis in COVID-19
Huub J. Weener et al
@andriesvdm.bsky.social @rvhelden.bsky.social @middeldorps.bsky.social
Reposted by Ruben van Helden
October 12, 2025 at 5:19 PM
Reposted by Ruben van Helden
Dit is echt steengoed! 👏
komende weken debunken we met BOOS de grootste migratiefabels die je hoort in media en politiek.
deze week: door statushouders kan jij geen woning krijgen. want dat zit net even anders.
hier onze video, vergeet 'm niet te delen: www.instagram.com/reel/DPME_CN...
deze week: door statushouders kan jij geen woning krijgen. want dat zit net even anders.
hier onze video, vergeet 'm niet te delen: www.instagram.com/reel/DPME_CN...
September 29, 2025 at 5:40 PM
Dit is echt steengoed! 👏
Reposted by Ruben van Helden
Over kogels en de kanten waar ze vandaan komen.
De tactiek werkt: bij (vermeend) geweld van links: luidkeels veroordelen. Bij geweld van rechts: oorverdovende stilte. Zo schuift het frame en de journalistiek mee.
September 13, 2025 at 8:39 PM
Over kogels en de kanten waar ze vandaan komen.
Reposted by Ruben van Helden
Mooi dat de SRV podcast terug is! @hakhverdian.bsky.social stukroodvlees.nl/aflevering-1...
Aflevering 134 – Verkiezingspotpourri, met Tom van der Meer - StukRoodVlees
We trappen het verkiezingsseizoen af met Tom van der Meer, hoogleraar politicologie aan de UvA. Tom en ik bespreken een hoop verschillende onderwerpen, waaronder de stand van zaken in de campagne (2:5...
stukroodvlees.nl
September 11, 2025 at 11:39 AM
Mooi dat de SRV podcast terug is! @hakhverdian.bsky.social stukroodvlees.nl/aflevering-1...
Reposted by Ruben van Helden
"climate realism" reading a lot like "sacrificing the global south and just shooting for 3 C"
www.cfr.org/article/our-...
www.cfr.org/article/our-...
Our Approach to Climate Policy Has Failed. It’s Time for Climate Realism
U.S. policymakers need a new strategy to confront the risks of climate change, compete in the global energy transition, and stay the course regardless of which political party is in power. A doctrine…
www.cfr.org
April 7, 2025 at 4:37 PM
"climate realism" reading a lot like "sacrificing the global south and just shooting for 3 C"
www.cfr.org/article/our-...
www.cfr.org/article/our-...
Impressive work showcasing the use of #Cardiac #Organoids in paving the way for personalized medicine in #DMD and #GeneTherapy.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Rapid and scalable personalized ASO screening in patient-derived organoids - Nature
A scalable platform for generating patient-specific organoids for testing personalized oligonucleotide therapeutics is described.
www.nature.com
February 6, 2025 at 9:21 PM
Impressive work showcasing the use of #Cardiac #Organoids in paving the way for personalized medicine in #DMD and #GeneTherapy.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Ruben van Helden
Incredible work! A study years in the making published in Nature. I’ve been waiting for this one.
Engineered heart muscle patches from iPSC improve cardiac function in non-human primates…and are stable/show evidence for remuscularization in a human patient! Wow! ❤️
www.nature.com/articles/s41...
Engineered heart muscle patches from iPSC improve cardiac function in non-human primates…and are stable/show evidence for remuscularization in a human patient! Wow! ❤️
www.nature.com/articles/s41...
Engineered heart muscle allografts for heart repair in primates and humans - Nature
Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading ...
www.nature.com
January 29, 2025 at 10:38 PM
Incredible work! A study years in the making published in Nature. I’ve been waiting for this one.
Engineered heart muscle patches from iPSC improve cardiac function in non-human primates…and are stable/show evidence for remuscularization in a human patient! Wow! ❤️
www.nature.com/articles/s41...
Engineered heart muscle patches from iPSC improve cardiac function in non-human primates…and are stable/show evidence for remuscularization in a human patient! Wow! ❤️
www.nature.com/articles/s41...
Reposted by Ruben van Helden
🔥Super excited to drop our recent preprint🔥
biorxiv.org/cgi/content/...
Here, we automated the generation of 3D Cardiac Microtissues and performed a small high-throughput screen to identify several novel anti-arrhythmic compounds for CPVT1 🧪❤️
#Cardiosky #Science #hiPSC #Arrhythmia #Stemcell
biorxiv.org/cgi/content/...
Here, we automated the generation of 3D Cardiac Microtissues and performed a small high-throughput screen to identify several novel anti-arrhythmic compounds for CPVT1 🧪❤️
#Cardiosky #Science #hiPSC #Arrhythmia #Stemcell
December 4, 2024 at 3:13 PM
🔥Super excited to drop our recent preprint🔥
biorxiv.org/cgi/content/...
Here, we automated the generation of 3D Cardiac Microtissues and performed a small high-throughput screen to identify several novel anti-arrhythmic compounds for CPVT1 🧪❤️
#Cardiosky #Science #hiPSC #Arrhythmia #Stemcell
biorxiv.org/cgi/content/...
Here, we automated the generation of 3D Cardiac Microtissues and performed a small high-throughput screen to identify several novel anti-arrhythmic compounds for CPVT1 🧪❤️
#Cardiosky #Science #hiPSC #Arrhythmia #Stemcell
Reposted by Ruben van Helden
🥼 A new personalized method reduces the time spent tailoring RNA drugs—from months to weeks. In a @nature.com paper, scientists used patient-derived cardiac #organoids to predict how rare genetic diseases respond to treatments.
via @science.org
via @science.org
Personalized miniorgans could speed treatments for rare diseases
Method shrinks time for testing tailored RNA drugs from months to weeks
bit.ly
February 6, 2025 at 5:26 PM
🥼 A new personalized method reduces the time spent tailoring RNA drugs—from months to weeks. In a @nature.com paper, scientists used patient-derived cardiac #organoids to predict how rare genetic diseases respond to treatments.
via @science.org
via @science.org
Reposted by Ruben van Helden
Created a starter pack focusing on disease modeling in a dish using stem cells! 🧪🔬
Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️
hPSC Disease Modeling: go.bsky.app/EpWsxNG
For a good general stem cell pack go here: go.bsky.app/UTW4d7b
Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️
hPSC Disease Modeling: go.bsky.app/EpWsxNG
For a good general stem cell pack go here: go.bsky.app/UTW4d7b
December 5, 2024 at 3:53 PM
Created a starter pack focusing on disease modeling in a dish using stem cells! 🧪🔬
Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️
hPSC Disease Modeling: go.bsky.app/EpWsxNG
For a good general stem cell pack go here: go.bsky.app/UTW4d7b
Please (self)nominate anyone you think should be added to the list and repost so it finds the right people ❤️
hPSC Disease Modeling: go.bsky.app/EpWsxNG
For a good general stem cell pack go here: go.bsky.app/UTW4d7b
Reposted by Ruben van Helden
A thread about being wrong:
5 years ago, we wrote a paper about how how newly enfranchised 16-year-olds vote in Austria. But we were wrong.
This year, @elisabethgraf.bsky.social, @schnizzl.bsky.social, Sylvia Kritzinger and I are setting the record straight: authors.elsevier.com/c/1juT5xRaZk...
5 years ago, we wrote a paper about how how newly enfranchised 16-year-olds vote in Austria. But we were wrong.
This year, @elisabethgraf.bsky.social, @schnizzl.bsky.social, Sylvia Kritzinger and I are setting the record straight: authors.elsevier.com/c/1juT5xRaZk...
November 21, 2024 at 6:01 PM
A thread about being wrong:
5 years ago, we wrote a paper about how how newly enfranchised 16-year-olds vote in Austria. But we were wrong.
This year, @elisabethgraf.bsky.social, @schnizzl.bsky.social, Sylvia Kritzinger and I are setting the record straight: authors.elsevier.com/c/1juT5xRaZk...
5 years ago, we wrote a paper about how how newly enfranchised 16-year-olds vote in Austria. But we were wrong.
This year, @elisabethgraf.bsky.social, @schnizzl.bsky.social, Sylvia Kritzinger and I are setting the record straight: authors.elsevier.com/c/1juT5xRaZk...