Rossella Di Giaimo
@rossdg.bsky.social
Professor of Molecular Biology and Neuroscientist 🇩🇪🇮🇹
Reposted by Rossella Di Giaimo
Three amazing days of the #neurogen2025 conference at @humantechnopole.bsky.social in Milan. Many thanks to all the participants, speakers and fellow co-organizers. We heard fantastic talks in #neurodevelopment #brainevolution #cancerneuroscience #neuroimmunology #neurodegeneration #neurodiversity
May 21, 2025 at 6:18 PM
Three amazing days of the #neurogen2025 conference at @humantechnopole.bsky.social in Milan. Many thanks to all the participants, speakers and fellow co-organizers. We heard fantastic talks in #neurodevelopment #brainevolution #cancerneuroscience #neuroimmunology #neurodegeneration #neurodiversity
Reposted by Rossella Di Giaimo
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
A human-specific enhancer fine-tunes radial glia potency and corticogenesis - Nature
HARE5, a human accelerated region enhancer, modulates cortical development by influencing neural progenitor cell behaviour, leading to an enlarged neocortex with increased functional independence betw...
www.nature.com
May 14, 2025 at 4:09 PM
Thrilled to share our latest study out in @natureportfolio.nature.com led by the fantastically talented Jing Liu. Our study provides insight into a long standing question in biology: What molecular features make us uniquely human and how do these function? www.nature.com/articles/s41...
Reposted by Rossella Di Giaimo
Excellent work from @silvianeuro.bsky.social lab, led by a brilliant young scholar, @mveronicapravata.bsky.social, on
the impact of a mutation in DCHS1 distinguishing sapiens from Neandertals: shifting the ratio between cortical & striatal progenitors
(Nice to see work going beyond the cortex) 🧪🧠🧬🧫
the impact of a mutation in DCHS1 distinguishing sapiens from Neandertals: shifting the ratio between cortical & striatal progenitors
(Nice to see work going beyond the cortex) 🧪🧠🧬🧫
DCHS1 Modulates Forebrain Proportions in Modern Humans via a Glycosylation Change
Comparative anatomical studies of primates and extinct hominins, including Neanderthals, show that the modern human brain is characterised by a disproportionately enlarged neocortex relative to the st...
www.biorxiv.org
May 15, 2025 at 5:59 AM
Excellent work from @silvianeuro.bsky.social lab, led by a brilliant young scholar, @mveronicapravata.bsky.social, on
the impact of a mutation in DCHS1 distinguishing sapiens from Neandertals: shifting the ratio between cortical & striatal progenitors
(Nice to see work going beyond the cortex) 🧪🧠🧬🧫
the impact of a mutation in DCHS1 distinguishing sapiens from Neandertals: shifting the ratio between cortical & striatal progenitors
(Nice to see work going beyond the cortex) 🧪🧠🧬🧫
Reposted by Rossella Di Giaimo
Looking forward to amazing days of talks&discussions #neurogen25 –Neurodev, evolution, de-& regeneration, organoids &more at @humantechnopole.bsky.social with @r3rt0.bsky.social
Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna
Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna
May 19, 2025 at 8:18 AM
Looking forward to amazing days of talks&discussions #neurogen25 –Neurodev, evolution, de-& regeneration, organoids &more at @humantechnopole.bsky.social with @r3rt0.bsky.social
Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna
Thanks to organisers @nereokalebic.bsky.social @harschnitz.bsky.social Jose Davila-Velderrain,Giuseppe Testa,Elena Taverna
Reposted by Rossella Di Giaimo
Yukiko Gotoh discussing Gene regulation in response to neuronal activity.
What makes intron length of neuronal genes longer? How do neurons manage to transcribe so long genes?
at #neurogen25
@nereokalebic.bsky.social @harschnitz.bsky.social
@humantechnopole.bsky.social
@r3rt0.bsky.social
What makes intron length of neuronal genes longer? How do neurons manage to transcribe so long genes?
at #neurogen25
@nereokalebic.bsky.social @harschnitz.bsky.social
@humantechnopole.bsky.social
@r3rt0.bsky.social
May 19, 2025 at 12:38 PM
Yukiko Gotoh discussing Gene regulation in response to neuronal activity.
What makes intron length of neuronal genes longer? How do neurons manage to transcribe so long genes?
at #neurogen25
@nereokalebic.bsky.social @harschnitz.bsky.social
@humantechnopole.bsky.social
@r3rt0.bsky.social
What makes intron length of neuronal genes longer? How do neurons manage to transcribe so long genes?
at #neurogen25
@nereokalebic.bsky.social @harschnitz.bsky.social
@humantechnopole.bsky.social
@r3rt0.bsky.social
Reposted by Rossella Di Giaimo
Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...
May 5, 2025 at 4:52 PM
Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...
Very happy to have contributed a little bit to this beautiful story! Great job by Francesco Di Matteo and @silvianeuro.bsky.social and the all team! Congrats!
February 18, 2025 at 9:10 PM
Very happy to have contributed a little bit to this beautiful story! Great job by Francesco Di Matteo and @silvianeuro.bsky.social and the all team! Congrats!
Reposted by Rossella Di Giaimo
Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants!
This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees
#Assembloids #Organoids #Brain
#CSHL2024Brain
This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees
#Assembloids #Organoids #Brain
#CSHL2024Brain
December 11, 2024 at 4:04 PM
Our 2024 CSHL conference on human brain development and stem cell models is in full swing, with over 300 participants!
This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees
#Assembloids #Organoids #Brain
#CSHL2024Brain
This year’s event features exciting new discoveries and dynamic discussions, driven largely by the energy & insights of trainees
#Assembloids #Organoids #Brain
#CSHL2024Brain
Happy to share our story on how we modeled EPM1 epilepsy in human brain #organoids during #neurodevelopment. Thanks to Silvia Cappello and all the authors!!! #organoids&assembloidsfeed
My first paper as lead author as a postdoc is out on bioRxiv! We show how CSTB influences ganglionic eminence development via intrinsic and extrinsic mechanisms. Huge thanks to @rossdg.bsky.social, Silvia Cappello, and the team for their collaboration on this exciting work!
Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy https://www.biorxiv.org/content/10.1101/2024.11.20.624470v1
November 22, 2024 at 9:27 AM
Happy to share our story on how we modeled EPM1 epilepsy in human brain #organoids during #neurodevelopment. Thanks to Silvia Cappello and all the authors!!! #organoids&assembloidsfeed
Reposted by Rossella Di Giaimo
My first paper as lead author as a postdoc is out on bioRxiv! We show how CSTB influences ganglionic eminence development via intrinsic and extrinsic mechanisms. Huge thanks to @rossdg.bsky.social, Silvia Cappello, and the team for their collaboration on this exciting work!
Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy https://www.biorxiv.org/content/10.1101/2024.11.20.624470v1
Intrinsic and extrinsic mechanisms alter neural cell fate specification in EPM1 Epilepsy https://www.biorxiv.org/content/10.1101/2024.11.20.624470v1
The extracellular milieu, including extracellular vesicles (EVs), plays a pivotal role in brain deve
www.biorxiv.org
November 22, 2024 at 6:27 AM
My first paper as lead author as a postdoc is out on bioRxiv! We show how CSTB influences ganglionic eminence development via intrinsic and extrinsic mechanisms. Huge thanks to @rossdg.bsky.social, Silvia Cappello, and the team for their collaboration on this exciting work!