Rita Ramalhete
@ritaramalhete.bsky.social
Try to pronounce my surname and you'll fail 🙃 🧫 🔬
Loves the tiny world of #microbiology 🦠
https://www.linkedin.com/in/ritaramalhete/
📍 London
Loves the tiny world of #microbiology 🦠
https://www.linkedin.com/in/ritaramalhete/
📍 London
Latest in our #Phages collection 👇 learn how phage and bacteria interact in the honeybee gut🐝
@springernature.com @natcomms.nature.com #bacteriophages
www.nature.com/collections/...
@springernature.com @natcomms.nature.com #bacteriophages
www.nature.com/collections/...
🐝🦠 New paper: rdcu.be/eOf7A
Phages may drive microbial diversity, yet we often don’t even know how phages & bacteria correlate in nature. Our new study tackles this in the honeybee gut, thanks to the great work of PhD student @malickndiaye.bsky.social at @dmf-unil.bsky.social @fbm-unil.bsky.social
Phages may drive microbial diversity, yet we often don’t even know how phages & bacteria correlate in nature. Our new study tackles this in the honeybee gut, thanks to the great work of PhD student @malickndiaye.bsky.social at @dmf-unil.bsky.social @fbm-unil.bsky.social
Phage diversity mirrors bacterial strain diversity in the honey bee gut microbiota - Nature Communications
Authors analyse paired viral and bacterial shotgun metagenomics data from individual honeybee guts, revealing modular, nested phage–bacteria networks, with viral diversity mirroring bacterial strain c...
www.nature.com
November 7, 2025 at 12:23 PM
Latest in our #Phages collection 👇 learn how phage and bacteria interact in the honeybee gut🐝
@springernature.com @natcomms.nature.com #bacteriophages
www.nature.com/collections/...
@springernature.com @natcomms.nature.com #bacteriophages
www.nature.com/collections/...
📢Attention Phage Phriends
🦠Happy #WorldPhageWeek
Check out our cross-journal Collection “Phages: from biology to the clinic”, with the latest on #phagebiology, phage–host interactions & #phagetherapy
#PhageResearch #Bacteriophages #NaturePortfolio
@natcomms.nature.com @natureportfolio.nature.com
🦠Happy #WorldPhageWeek
Check out our cross-journal Collection “Phages: from biology to the clinic”, with the latest on #phagebiology, phage–host interactions & #phagetherapy
#PhageResearch #Bacteriophages #NaturePortfolio
@natcomms.nature.com @natureportfolio.nature.com
Phages: from biology to the clinic
This cross-journal Collection welcomes manuscripts covering a broad spectrum of research related to phages, including fundamental studies on phage biology and ...
www.nature.com
October 28, 2025 at 9:08 AM
📢Attention Phage Phriends
🦠Happy #WorldPhageWeek
Check out our cross-journal Collection “Phages: from biology to the clinic”, with the latest on #phagebiology, phage–host interactions & #phagetherapy
#PhageResearch #Bacteriophages #NaturePortfolio
@natcomms.nature.com @natureportfolio.nature.com
🦠Happy #WorldPhageWeek
Check out our cross-journal Collection “Phages: from biology to the clinic”, with the latest on #phagebiology, phage–host interactions & #phagetherapy
#PhageResearch #Bacteriophages #NaturePortfolio
@natcomms.nature.com @natureportfolio.nature.com
Your weekend read
VAP is one of the most common hospital-acquired infections, but #phages are here to help 🤝 In a murine model of VAP, the combination of phage and antibiotic therapy led to faster clinical improvement and prevented epithelial cell damage🐁🫁
#phagetherapy #VAP #pneumonia
VAP is one of the most common hospital-acquired infections, but #phages are here to help 🤝 In a murine model of VAP, the combination of phage and antibiotic therapy led to faster clinical improvement and prevented epithelial cell damage🐁🫁
#phagetherapy #VAP #pneumonia
Read our latest #research on #phages #VAP, published with @springernature.com in @natcomms.nature.com.
Phages synergize with antibiotics and alleviate ventilator-induced pneumonia. Read more here: rdcu.be/el5ep
Phages synergize with antibiotics and alleviate ventilator-induced pneumonia. Read more here: rdcu.be/el5ep
Adjunctive phage therapy improves antibiotic treatment of ventilator-associated-pneumonia with Pseudomonas aeruginosa
Nature Communications - Multidrug-resistant pathogens have become increasingly common in hospital settings. Here, the authors investigate the efficacy of adjunctive antibiotic and phage therapy in...
rdcu.be
October 24, 2025 at 11:09 AM
Your weekend read
VAP is one of the most common hospital-acquired infections, but #phages are here to help 🤝 In a murine model of VAP, the combination of phage and antibiotic therapy led to faster clinical improvement and prevented epithelial cell damage🐁🫁
#phagetherapy #VAP #pneumonia
VAP is one of the most common hospital-acquired infections, but #phages are here to help 🤝 In a murine model of VAP, the combination of phage and antibiotic therapy led to faster clinical improvement and prevented epithelial cell damage🐁🫁
#phagetherapy #VAP #pneumonia
Satisfaction during your #PhD is multifactorial. It's not only how *happy* you feel, but how you're supported within your environment. Beyond #funding, quality supervision and a healthy #worklifebalance are essential for students to feel supported and engaged.
#PhDlife #PhDstudent #Research
#PhDlife #PhDstudent #Research
We asked 3,785 PhD students across 107 countries about their experiences. Where do you think the happiest doctoral candidates were?
go.nature.com/3Wzz2lL
go.nature.com/3Wzz2lL
Are these the happiest PhD students in the world?
Brazil, Australia and Italy have the highest satisfaction scores in Nature’s global 2025 PhD survey — but are these nations really the best places to do a doctorate?
go.nature.com
October 21, 2025 at 8:59 AM
Satisfaction during your #PhD is multifactorial. It's not only how *happy* you feel, but how you're supported within your environment. Beyond #funding, quality supervision and a healthy #worklifebalance are essential for students to feel supported and engaged.
#PhDlife #PhDstudent #Research
#PhDlife #PhDstudent #Research
In elephant news 🐘 A study led by the University of Surrey shows that a new vaccine can activate the immune system against EEHV, a deadly virus that affects many young African and Asian elephants. Read about their proof-of-concept trial here ⬇️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
One of our top-rated articles on @altmetric.com this past week was published open access in @natcomms.nature.com. Read 'A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study' here: www.nature.com/articles/s41...
#epidemiology #episky
#epidemiology #episky
A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study - Nature Communications
Elephant endotheliotropic herpesvirus (EEHV) haemorrhagic disease is a major threat for juvenile Asian elephants. This study reports a proof-of-concept trial that evaluates the safety and immunogenicity of a vaccine against EEHV.
www.nature.com
October 14, 2025 at 9:10 AM
In elephant news 🐘 A study led by the University of Surrey shows that a new vaccine can activate the immune system against EEHV, a deadly virus that affects many young African and Asian elephants. Read about their proof-of-concept trial here ⬇️
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Did you know that the #T4SS can also mediate biofilm formation?🧫 A #Crohnsdisease associated E. coli strain carries a hybrid T4SS that drives pilin polymerization and #biofilm formation, leading to enhanced fitness in the gut. Read about it here ⬇️ @natcomms.nature.com #naturecommunications
Happy to share our latest pub in @natcomms.nature.com led by my trainee Jonas Wong www.nature.com/articles/s41.... We identified an 'unusual' T4SS used by Crohn's E. coli to make biofilms and ⬆️ inflammation. We're hiring a PDF to continue this. Details: iaejup.fa.ocs.oraclecloud.com/hcmUI/Candid...
The assembly of a hybrid type IV secretion system by a Crohn’s disease-associated Escherichia coli strain - Nature Communications
Adherent-invasive strains of E. coli are commonly isolated from patients with Crohn’s disease. Here, the authors show that an AIEC harbours a hybrid Type IV secretion system (T4SS) that mediates pilin polymerization and biofilm formation in vivo.
www.nature.com
October 9, 2025 at 9:52 AM
Did you know that the #T4SS can also mediate biofilm formation?🧫 A #Crohnsdisease associated E. coli strain carries a hybrid T4SS that drives pilin polymerization and #biofilm formation, leading to enhanced fitness in the gut. Read about it here ⬇️ @natcomms.nature.com #naturecommunications
A fresh of the press with a brilliant accompanying thread! Great work by @aliciapcv.bsky.social and colleagues @cnb-csic.bsky.social 👏 #plasmidbiology
This work is finally published! 🥳🧬
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Plasmids are associated with very variable fitness costs in their different bacterial hosts. But, what is the contribution of each of the plasmid-genes in these host-specific effects? Study led by
@jorgesastred.bsky.social, @sanmillan.bsky.social and myself! 1/14
Dissecting pOXA-48 fitness effects in clinical Enterobacterales using plasmid-wide CRISPRi screens
Nature Communications - This study investigates the effects of the carbapenem resistance plasmid pOXA-48 in clinical enterobacteria. Using CRISPRi screens, the authors revealed that the...
rdcu.be
August 21, 2025 at 8:50 AM
A fresh of the press with a brilliant accompanying thread! Great work by @aliciapcv.bsky.social and colleagues @cnb-csic.bsky.social 👏 #plasmidbiology
The mRNA tech strikes *yet* again
Two vaccine candidates using mRNA technology elicit a potent immune response against HIV
go.nature.com/4ov7WZI
go.nature.com/4ov7WZI
mRNA vaccines for HIV trigger strong immune response in people
Results from early-stage trial show that 80% of participants who received one of two HIV vaccine candidates produced antibodies against viral proteins.
go.nature.com
August 1, 2025 at 8:46 AM
The mRNA tech strikes *yet* again
Reposted by Rita Ramalhete
Excited to share our latest work using AI-designed proteins to block heme-piracy by E. coli. Published in @natcomms.nature.com. A team effort between my lab and the @knottrna.bsky.social lab, with experimental work led by the talented @danielrfox.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Inhibiting heme piracy by pathogenic Escherichia coli using de novo-designed proteins - Nature Communications
Many pathogens encode transporters that extract heme directly from host proteins. In this study, the authors demonstrate the utility of de novo-designed proteins in understanding the mechanism behind ...
www.nature.com
July 9, 2025 at 11:55 PM
Excited to share our latest work using AI-designed proteins to block heme-piracy by E. coli. Published in @natcomms.nature.com. A team effort between my lab and the @knottrna.bsky.social lab, with experimental work led by the talented @danielrfox.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Rita Ramalhete
I am very happy to share our latest study on ciprofloxacin resistance instability in P. aeruginosa during periods of drug restriction. A fantastic collaboration @pablolaborda.bsky.social, RuggeroLaRosa, JLMartínez, SørenMolin & HelleJohansen 🥳 @cnb-csic.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Ciprofloxacin resistance rapidly declines in nfxB defective clinical strains of Pseudomonas aeruginosa - Nature Communications
Antimicrobial resistance can decline due to compensatory mutations or genetic reversions to wild-type alleles. Here, the authors analyse the decline of ciprofloxacin resistance in nfxB-defective Pseud...
www.nature.com
June 4, 2025 at 9:23 AM
I am very happy to share our latest study on ciprofloxacin resistance instability in P. aeruginosa during periods of drug restriction. A fantastic collaboration @pablolaborda.bsky.social, RuggeroLaRosa, JLMartínez, SørenMolin & HelleJohansen 🥳 @cnb-csic.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The rhetorical question. However, it comes a point when all our spoken languages get jumbled up in our brains and we start speaking a mix of all 😅
Numerous studies have shown that bilinguals undergo a later onset of dementia, perhaps of around four years, on average—though some of these have failed to replicate. The good news is that it is never too late to start learning https://econ.trib.al/weUpnrW
Is being bilingual good for your brain?
Perhaps. Learning languages offers other, more concrete benefits
econ.trib.al
July 24, 2025 at 1:23 PM
The rhetorical question. However, it comes a point when all our spoken languages get jumbled up in our brains and we start speaking a mix of all 😅
Reposted by Rita Ramalhete
Now published, congrats Bevika, Kinki, Vincent, Florian and Paddy! #MicroSky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
July 14, 2025 at 9:16 PM
Now published, congrats Bevika, Kinki, Vincent, Florian and Paddy! #MicroSky
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Very exciting new collection on the clinical #microbiome 🦠
New collection on the clinical #microbiome from @naturemedicine.bsky.social @naturemicrobiol.bsky.social @naturecomms.bsky.social @commsmed.bsky.social open for submissions!
More info on how to submit here www.nature.com/collections/...
#Gastrosky #microsky 🧪
More info on how to submit here www.nature.com/collections/...
#Gastrosky #microsky 🧪
March 12, 2025 at 12:36 PM
Very exciting new collection on the clinical #microbiome 🦠