R. David Britt
@rdavbritt.bsky.social
Chemistry Professor, UC Davis
Reposted by R. David Britt
I am very excited to share our new preprint - "A Zundel Ion in the Catalytic Proton Transfer Pathway of [FeFe]-Hydrogenase" - for which we revisited an older theory of ours, and came to surprising conclusions... 🧵
doi.org/10.26434/che...
doi.org/10.26434/che...
November 6, 2025 at 12:40 PM
I am very excited to share our new preprint - "A Zundel Ion in the Catalytic Proton Transfer Pathway of [FeFe]-Hydrogenase" - for which we revisited an older theory of ours, and came to surprising conclusions... 🧵
doi.org/10.26434/che...
doi.org/10.26434/che...
Reposted by R. David Britt
Vincent, Morra, and Rodríguez-Maciá demonstrate that truncating the electron transfer domain of [FeFe]-hydrogenase does *not* diminish their catalytic efficiency (via ACS Catalysis).
doi.org/10.1021/acsc...
doi.org/10.1021/acsc...
Engineering the Electron Relay in [FeFe]-Hydrogenase Enhances Electrocatalytic H2 Evolution
H2 is an ideal energy vector, but catalysts for its clean production from water are inefficient or expensive. [FeFe]-hydrogenases are the most active H2-converting catalysts in nature, using a unique ...
doi.org
November 7, 2025 at 7:20 AM
Vincent, Morra, and Rodríguez-Maciá demonstrate that truncating the electron transfer domain of [FeFe]-hydrogenase does *not* diminish their catalytic efficiency (via ACS Catalysis).
doi.org/10.1021/acsc...
doi.org/10.1021/acsc...
Fall S. leucophylla pitchers...
October 11, 2025 at 9:54 PM
Fall S. leucophylla pitchers...
Reposted by R. David Britt
John Clarke, Michel H. Devoret, and John M. Martinis have won the 2025 #NobelPrize in Physics for experiments that revealed quantum behavior in electrical circuits, showing that even systems made of billions of atoms can obey the strange laws of the quantum world: cen.acs.org/people/nobel... 🧪
October 7, 2025 at 1:22 PM
John Clarke, Michel H. Devoret, and John M. Martinis have won the 2025 #NobelPrize in Physics for experiments that revealed quantum behavior in electrical circuits, showing that even systems made of billions of atoms can obey the strange laws of the quantum world: cen.acs.org/people/nobel... 🧪
Paul McCartney, Oct 4 2025
October 5, 2025 at 3:46 PM
Paul McCartney, Oct 4 2025
Reposted by R. David Britt
ACS Electrochemistry (open) Coupled Benchtop NMR and EPR of Viologen Radicals in a Redox Flow Battery, Giu A. Silva Testa, Mathijs A. Damhuis, Tom Speelman, Kim Baas, Johannes A.A.W. Elemans*, Evan Wenbo Zhao* pubs.acs.org/doi/10.1021/... #NMRchat #NMR #EPR #ESR #BenchtopNMR #Battchat 🧲
Coupled Benchtop NMR and EPR Spectroscopy Reveals the Electronic Structure of Viologen Radicals in a Redox Flow Battery
Viologens are a class of organic molecules with promising properties for redox flow battery applications. However, their molecular-level mechanisms remain challenging to fully probe and understand. In...
pubs.acs.org
September 24, 2025 at 2:28 PM
ACS Electrochemistry (open) Coupled Benchtop NMR and EPR of Viologen Radicals in a Redox Flow Battery, Giu A. Silva Testa, Mathijs A. Damhuis, Tom Speelman, Kim Baas, Johannes A.A.W. Elemans*, Evan Wenbo Zhao* pubs.acs.org/doi/10.1021/... #NMRchat #NMR #EPR #ESR #BenchtopNMR #Battchat 🧲
OMG, thanks for catching! (It's only good for one pulse experiments???)
September 24, 2025 at 2:31 PM
OMG, thanks for catching! (It's only good for one pulse experiments???)
A paper describing the performance of our new TWT powered 263 GHz pulse EPR spectrometer is now available as a preprint
www.researchsquare.com/article/rs-7...
www.researchsquare.com/article/rs-7...
Very high frequency (263 GHz) pulse EPR spectroscopy of high spin transition metal centers
Pulse Electron Paramagnetic Resonance (EPR) spectroscopy provides powerful tools for examining species with unpaired electrons, such as organic radicals and metal ions,
in a wide variety of interest...
www.researchsquare.com
September 24, 2025 at 2:08 PM
A paper describing the performance of our new TWT powered 263 GHz pulse EPR spectrometer is now available as a preprint
www.researchsquare.com/article/rs-7...
www.researchsquare.com/article/rs-7...
Reposted by R. David Britt
We celebrated Fede's PhD defense yesterday 🎉
Together we've been working on cytochrome c oxidase for the last 6-7 years.
www.sciencedirect.com/science/arti...
Dr. Baserga is looking for a job in tech now www.linkedin.com/in/federico-...
Together we've been working on cytochrome c oxidase for the last 6-7 years.
www.sciencedirect.com/science/arti...
Dr. Baserga is looking for a job in tech now www.linkedin.com/in/federico-...
September 23, 2025 at 4:49 AM
We celebrated Fede's PhD defense yesterday 🎉
Together we've been working on cytochrome c oxidase for the last 6-7 years.
www.sciencedirect.com/science/arti...
Dr. Baserga is looking for a job in tech now www.linkedin.com/in/federico-...
Together we've been working on cytochrome c oxidase for the last 6-7 years.
www.sciencedirect.com/science/arti...
Dr. Baserga is looking for a job in tech now www.linkedin.com/in/federico-...
Reposted by R. David Britt
Postdoctoral research position in Rob Tycko's group in the Laboratory of Chemical Physics, NIDDK #NIH Bethesda, Maryland, development and application of time-resolved solid-state NMR, email your CV incl education & research accomplishments to www.niddk.nih.gov/about-niddk/... #NMRjobs 🧲
Robert Tycko, Ph.D., NIH Distinguished Investigator - NIDDK
www.niddk.nih.gov
September 23, 2025 at 1:26 PM
Postdoctoral research position in Rob Tycko's group in the Laboratory of Chemical Physics, NIDDK #NIH Bethesda, Maryland, development and application of time-resolved solid-state NMR, email your CV incl education & research accomplishments to www.niddk.nih.gov/about-niddk/... #NMRjobs 🧲
I had to run over in the middle and flip it!
CD??? We had a 78 rpm vinyl fill track!
My grad school lab had a special helium fill soundtrack, which was burned on a CD because that's how long ago it was. We never listened to it at other times, only when doing the fills. It contained the cheesiest songs we could think of, and everyone would sing along at top volume.
September 5, 2025 at 9:05 PM
I had to run over in the middle and flip it!
Reposted by R. David Britt
Our article "H2-producing catalysts based on ferredoxin scaffolds" is online with full citation details now!
doi.org/10.1002/advs...
doi.org/10.1002/advs...
Hydrogen‐Producing Catalysts Based on Ferredoxin Scaffolds
Selected plant-type ferredoxins that lack their natural [2Fe-2S] clusters functionally bind a hydrogenase active site cofactor and act as hydrogenases themselves. In combination with photosystem I, t...
doi.org
September 5, 2025 at 12:29 PM
Our article "H2-producing catalysts based on ferredoxin scaffolds" is online with full citation details now!
doi.org/10.1002/advs...
doi.org/10.1002/advs...
CD??? We had a 78 rpm vinyl fill track!
My grad school lab had a special helium fill soundtrack, which was burned on a CD because that's how long ago it was. We never listened to it at other times, only when doing the fills. It contained the cheesiest songs we could think of, and everyone would sing along at top volume.
September 5, 2025 at 9:01 PM
CD??? We had a 78 rpm vinyl fill track!
ok, first attempt at a Lotus in Point Richmond seems to be going fine
September 4, 2025 at 8:11 PM
ok, first attempt at a Lotus in Point Richmond seems to be going fine
is the dimer core of the H-cluster of FeFe hydrogenase formed by rSAM chemistry in HydE?
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
The Radical S-Adenosyl-l-methionine Enzyme HydE Forms an Fe(I)Fe(I) Dimer En Route to the [FeFe] Hydrogenase H-Cluster
[FeFe] hydrogenases are highly efficient metalloenzymes that catalyze hydrogen conversion via a sophisticated active site cofactor known as the H-cluster. Biosynthesis of its [2Fe]H subcluster, which ...
pubs.acs.org
August 30, 2025 at 5:28 PM
is the dimer core of the H-cluster of FeFe hydrogenase formed by rSAM chemistry in HydE?
pubs.acs.org/doi/full/10....
pubs.acs.org/doi/full/10....
a company (I will not name here) decided to throw away money by setting up a solar array AND Tesla Powerwall at the house, charge us a flat rate for the next 25 years, and it starts for less that we were paying for PG&E power before. Yes solar is just a fantasy power source.
August 23, 2025 at 9:19 PM
a company (I will not name here) decided to throw away money by setting up a solar array AND Tesla Powerwall at the house, charge us a flat rate for the next 25 years, and it starts for less that we were paying for PG&E power before. Yes solar is just a fantasy power source.
Reposted by R. David Britt
Angewandte Chemie (open) mini-review, Electron Spin Resonance at the Single-Molecule Scale, Lisanne Sellies*, Jascha Repp* onlinelibrary.wiley.com/doi/10.1002/... #NMRchat #EPR #ESR 🧲
Electron Spin Resonance at the Single‐Molecule Scale
This minireview provides an overview of the four electron-spin-resonance techniques with single-molecule sensitivity, relying on either optically detected magnetic resonance or scanning-probe microsc...
onlinelibrary.wiley.com
August 22, 2025 at 2:22 PM
Angewandte Chemie (open) mini-review, Electron Spin Resonance at the Single-Molecule Scale, Lisanne Sellies*, Jascha Repp* onlinelibrary.wiley.com/doi/10.1002/... #NMRchat #EPR #ESR 🧲
Breanne of Tarth says this place is pretty cool!
August 4, 2025 at 3:58 PM
Breanne of Tarth says this place is pretty cool!
"echo" a clue in NYT connections today, but no obvious words like "spin" or "Hahn"
August 3, 2025 at 3:41 PM
"echo" a clue in NYT connections today, but no obvious words like "spin" or "Hahn"
ahh, the inherited EPR concept...
Choir of angels singing, etc. This lab ain’t perfect but I’m glad we could get the floors cleaned before we put another giant magnet in the corner. I am most delighted about this corner behind the spectrometer that hasn’t been scrubbed/waxed in like 30+ years.
July 24, 2025 at 4:19 PM
ahh, the inherited EPR concept...
Reposted by R. David Britt
Writing in @jacs.acspublications.org, Tom @rauchfuz.bsky.social et al. report the synthesis and XRD/FTIR characterization of "Complex-B", the biosynthetic precursor to the [FeFe]-hydrogenase active site cofactor.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Characterization of Complex-B ([Fe(κ3-cys)(CN)(CO)2]−), Biosynthetic Precursor to the [FeFe]-Hydrogenase Active Site, and Related Complexes
The preparation, spectroscopy, and structure are described for [Fe(κ3-cys)(CN)(CO)2]− ([2]−). Otherwise known as complex-B, this coordination complex is an early intermediate in the biosynthesis of th...
pubs.acs.org
July 19, 2025 at 10:39 AM
Writing in @jacs.acspublications.org, Tom @rauchfuz.bsky.social et al. report the synthesis and XRD/FTIR characterization of "Complex-B", the biosynthetic precursor to the [FeFe]-hydrogenase active site cofactor.
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
Reposted by R. David Britt
International EPR Society (IES) Best Paper Awards 2024/2025 @epr-esr.bsky.social ieprs.org/best-paper-a... #EPR #ESR #NMRchat 🧲
🏆 Daniele Panariti (University of Padova, Italy) pubs.rsc.org/en/content/a...
🏆 Mikhail Kolokolov (International Tomography Center, Russia) pubs.acs.org/doi/full/10....
🏆 Daniele Panariti (University of Padova, Italy) pubs.rsc.org/en/content/a...
🏆 Mikhail Kolokolov (International Tomography Center, Russia) pubs.acs.org/doi/full/10....
July 18, 2025 at 2:28 PM
International EPR Society (IES) Best Paper Awards 2024/2025 @epr-esr.bsky.social ieprs.org/best-paper-a... #EPR #ESR #NMRchat 🧲
🏆 Daniele Panariti (University of Padova, Italy) pubs.rsc.org/en/content/a...
🏆 Mikhail Kolokolov (International Tomography Center, Russia) pubs.acs.org/doi/full/10....
🏆 Daniele Panariti (University of Padova, Italy) pubs.rsc.org/en/content/a...
🏆 Mikhail Kolokolov (International Tomography Center, Russia) pubs.acs.org/doi/full/10....