Louise Marston
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proflouisemarston.bsky.social
Louise Marston
@proflouisemarston.bsky.social
100 followers 67 following 81 posts
Professor of Clinical Trials Statistics at Priment Clinical Trials Unit, UCL. England rugby fan, Trailfinders Women. Often out taking photographs.
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Reposted by Louise Marston
ucl-primarycare.bsky.social
🎉 Big congrats to Tas Rookes for passing her PhD viva with flying colours!
🧠 Thesis: Improving engagement in health promotion for older adults with mild cognitive impairment
👏 Supervised by Professor Kate Walters, Louise Marston, Rachael Frost, Megan Armstrong & Yolanda Barrado-Martín
a picture of a graduation cap and tassel with the words congrats you did it
ALT: a picture of a graduation cap and tassel with the words congrats you did it
media.tenor.com
November 4, 2025 at 4:16 PM
Reposted by Louise Marston
mrcctu.bsky.social
We're excited to share our latest work on estimands in clinical trials!

📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands.

🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...
Sage Journals: Discover world-class research
Subscription and open access journals from Sage, the world's leading independent academic publisher.
journals.sagepub.com
October 27, 2025 at 2:42 PM
Reposted by Louise Marston
justinyang.me
Apply to work with me and a great team at @uclpsychiatry.bsky.social to do some exciting research using electronic health records! The position is funded for 19 months in the first instance and you’ll be joining a fascinating NIHR project: www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
October 17, 2025 at 8:40 AM
proflouisemarston.bsky.social
Evidence for health promotion interventions to improve cognitive and physical functioning outcomes in older adults with MCI: A state-of-the-art review www.sciencedirect.com/science/arti... @ucl-caps.bsky.social @ucl-primarycare.bsky.social @drmegs.bsky.social @tasminrookes.bsky.social
Background Health promotion activities for people with mild cognitive impairment (MCI) may improve their overall health and prevent progression to dementia. We need to understand the best approaches to behaviour change in this population. Aim To summarise the types of health promotion interventions and current clinical effectiveness evidence for physical and cognitive functioning outcomes in people with MCI. Design State-of-the art review Method Medline was searched in April 2025, for systematic reviews synthesising randomised controlled trials testing effectiveness of health promotion interventions in older adults with MCI, published since 2015. Abstracts, titles, and full texts were single screened and, for eligible reviews, the characteristics, intervention type, primary outcome, and evidence for people with MCI, were extracted. Key messages were narratively synthesised across reviews, grouping by type of intervention and outcome measure. Results From 1776 titles and abstracts, 57 systematic reviews were eligible. Regular moderate intensity multicomponent physical exercise and memory-focussed cognitive training interventions had the strongest evidence base for improving cognitive functioning. However, combining physical exercise and cognitive training was more beneficial for cognitive domains and physical functioning, in comparison to doing them individually. The evidence for nutrition interventions was mixed. One review of psychological interventions showed improvements for wellbeing. Conclusion There is evidence that health promotion interventions can support people with MCI and dementia to improve or maintain their cognitive function, through multicomponent physical activity combined with cognitive training. More evidence is needed for nutritional recommendations, psychological interventions, and social inclusion interventions.
October 7, 2025 at 6:26 PM
Reposted by Louise Marston
ucl-primarycare.bsky.social
📢 New Publication Alert
Congratulations to @Roganie Govender and the entire team on their latest publication! A fantastic achievement!
@ucl-primarycare.bsky.social
bmjopen.bmj.com/content/15/9...
Swallowing prehabilitation for people with head and neck cancer: a pilot cluster-randomised feasibility trial of the SIP SMART intervention
Objectives To assess the feasibility of delivering the swallowing prehabilitation intervention known as Swallowing Intervention Package: Self-Monitoring, Assessment and Rehabilitation Training (SIP SM...
bmjopen.bmj.com
September 26, 2025 at 5:05 PM
Reposted by Louise Marston
ukcrc-ctu.org.uk
Every data point tells a story.

Statisticians ensure those stories are heard—spotting safety concerns, reducing bias, and ensuring ethical outcomes in clinical trials.

🔗 ukcrc-ctu.org.uk

#Statistics #UKCTUNetwork #WorldPatientSafetyDay2025
September 17, 2025 at 8:47 AM
Reposted by Louise Marston
ucl-primarycare.bsky.social
📢 New dataset drop!
The BRHS @ucl-brhs.bsky.social is now available via @ukdataservice.bsky.social 🎉
🔗 ukdataservice.ac.uk
7,735 men tracked over 50 years = goldmine for research on heart health, ageing & behaviour.
Prof. Wannamethee: “Unparalleled insights into ageing & heart health.”
September 4, 2025 at 10:03 AM
Reposted by Louise Marston
jama.com
📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research.

ja.ma/4fzMVZS
Figure. SPIRIT 2025 Diagram of the Schedule of Enrollment, Interventions, and Assessments
August 10, 2025 at 4:00 PM
proflouisemarston.bsky.social
Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT NIHR report out today www.journalslibrary.nihr.ac.uk/hta/MKAC9495 @nihr.bsky.social @ucl-primarycare.bsky.social @gnielsenphysio.bsky.social @jonstoneneuro.bsky.social
July 31, 2025 at 5:58 PM
proflouisemarston.bsky.social
Methylphenidate versus placebo for fatigue in patients with advanced cancer: the MePFAC randomised controlled trial @nihr.bsky.social report out today. @ucl-primarycare.bsky.social www.journalslibrary.nihr.ac.uk/hta/GJPS6321
Front page of the MePFAC HTA report with abstract.
July 31, 2025 at 4:47 PM
Reposted by Louise Marston
ucliehc.bsky.social
Want to help shape national dementia prevention strategies?

We're looking for a Research Assistant on the PRACTICAL study ▶️ www.ucl.ac.uk/work-at-ucl/...

Closing date: 13 Jul 2025
@ucl-primarycare.bsky.social
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
July 2, 2025 at 8:35 AM
Reposted by Louise Marston
ucl-primarycare.bsky.social
🎉 Huge congratulations to our PhD candidate, Dennis Emaralino, for successfully passing his PhD upgrade last week! His project, Anxiety, Depression, and Mental Wellbeing Among Young Adults in the Philippines. Very well done! 👏
Slide from a PhD upgrade presentation titled "Anxiety, Depression and Mental Wellbeing Among Young Adults (18 to 25 years old) in the Philippines." The presentation is by Dennis Emralino Dantic from University College London, dated June 2025. Supervisors listed are Professor Louise Marston and Dr. Rafael Gafoor. In the bottom right corner, there is a video overlay of the presenter, Dennis Emralino Dantic, wearing a light blue collared shirt, speaking in front of a plain background. The UCL logo is visible in the top right corner of the slide.
June 10, 2025 at 10:10 AM
Reposted by Louise Marston
ucliehc.bsky.social
We're excited to advertise a permanent role as a Clinical Lecturer in Primary Care (0.6FTE) in our Institute for a GP holding a PhD or equivalent qualification who would like to develop a career as an academic in research and education.

Click here for more details: www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
www.ucl.ac.uk
June 1, 2025 at 2:02 PM
Reposted by Louise Marston
profpaolazaninotto.bsky.social
What a great PhD Research day we had at the UCL IEHC! Poster presentations and 3min thesis completion! Well done everyone 👏👏👏👏
May 1, 2025 at 8:14 PM
Reposted by Louise Marston
jama.com
The CONSORT and SPIRIT statements for randomized trials have been updated for 2025 and published in JAMA, with a new focus on open science principles and guidance on trial registration, data access, and conflict of interest reporting.

➡ CONSORT 2025: ja.ma/3Yyu0Hh
➡ SPIRIT 2025: ja.ma/3YjFfn8
April 29, 2025 at 2:00 PM
Reposted by Louise Marston
gscollins.bsky.social
NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social

—> www.bmj.com/content/389/...

#openscience #transparency #medsky #statssky #episky
April 15, 2025 at 5:55 AM
proflouisemarston.bsky.social
The association between relapse and the outcome of schizophrenia and recurrent psychotic disorders doi.org/10.1192/bjp.... @joannamoncrieff.bsky.social @soniajohnson1.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social
Abstract from BJPsych for paper: The association between relapse and the outcome of schizophrenia and recurrent psychotic disorders.
April 14, 2025 at 6:37 PM
Reposted by Louise Marston
mrcctu.bsky.social
Estimands define the research question in #ClinicalTrials to help stakeholders understand and interpret trial results and make better decisions about treatments.

Our latest video explores the importance of estimands in the context of a mental health trial. Watch now ▶️👇
buff.ly/xiz3mU6 #StatsSky
What are estimands?
Estimands are a way of describing the research question in a clinical trial. They can help doctors, patients, policymakers and other stakeholders understand ...
youtu.be
April 14, 2025 at 11:02 AM
Reposted by Louise Marston
proflouisemarston.bsky.social
researchinvolvement.biomedcentral.com/articles/10.... PETAL PPIE involvement in developing the intervention. @proflikahass.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social
March 6, 2025 at 3:31 PM
Reposted by Louise Marston
ucldiscovery.bsky.social
Open Access UCL Research: Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand discovery.ucl.ac.uk/id/eprint/10...
March 11, 2025 at 10:30 AM
proflouisemarston.bsky.social
A personalised health intervention to maintain independence in older people with mild frailty: a process evaluation within the HomeHealth RCT doi.org/10.3310/MBCV... @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social @ucl-caps.bsky.social
pendingpublications
Pending Publication
doi.org
April 3, 2025 at 6:20 PM
Reposted by Louise Marston
gnielsenphysio.bsky.social
The economic evaluation of the Physio4FMD trial was finally published today!
www.neurology.org/doi/10.1212/...
@jonstoneneuro.bsky.social
Cost Utility of Specialist Physiotherapy for Functional Motor Disorder (Physio4FMD) | Neurology Clinical Practice
Background and ObjectivesFunctional motor disorder (FMD), a motor-dominant variant of functional neurologic disorder, is a disabling condition associated with high health and social care resource use ...
www.neurology.org
April 2, 2025 at 9:45 PM
Reposted by Louise Marston
statsci.bsky.social
@suziecro.bsky.social Introducing what is sure to be an exciting day ahead at the 2nd Contemporary Clinical Trials Methodology Meeting! #cctmm25
April 2, 2025 at 9:34 AM
proflouisemarston.bsky.social
Cost Utility of Specialist Physiotherapy for Functional Motor Disorder (Physio4FMD) www.neurology.org/doi/10.1212/... @ucl-primarycare.bsky.social
Cost Utility of Specialist Physiotherapy for Functional Motor Disorder (Physio4FMD) | Neurology Clinical Practice
Background and ObjectivesFunctional motor disorder (FMD), a motor-dominant variant of functional neurologic disorder, is a disabling condition associated with high health and social care resource use ...
www.neurology.org
April 2, 2025 at 6:23 AM
proflouisemarston.bsky.social
In-patient service use before and after a mental health in-patient rehabilitation admission in @bjpsych.bsky.social Open doi.org/10.1192/bjo.... @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social Part of Christian Dalton-Locke's PhD.
In-patient service use before and after a mental health in-patient rehabilitation admission | BJPsych Open | Cambridge Core
In-patient service use before and after a mental health in-patient rehabilitation admission - Volume 11 Issue 3
doi.org
April 1, 2025 at 1:40 PM