Pierre Dupuy
pierredupuy.bsky.social
Pierre Dupuy
@pierredupuy.bsky.social
CNRS researcher. PhD in Microbiology. Mycobacteria, Stress response, DNA repair.
Reposted by Pierre Dupuy
Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org!
It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance.
Huge congrats to Wendy & colleagues!
shorturl.at/WbFQC
Inorganic sulfate is critical for Mycobacterium tuberculosis lung tissue colonization and redox balance | PNAS
Tuberculosis remains the deadliest infectious disease caused by a single pathogen, highlighting the urgent need for novel therapies. A deeper under...
www.pnas.org
September 23, 2025 at 3:32 AM
After a PhD and two postdocs, I’m very proud to be joining the CNRS as a Chargé de recherche, this is a meaningful milestone. Huge thanks to Claude Bruand, @michaelglickman.bsky.social, and @oneyrolles.bsky.social for their guidance and support. Olivier, let’s turn this into exciting discoveries!
June 12, 2025 at 2:35 PM
Reposted by Pierre Dupuy
Pleased to highlight a new preprint from the lab. This is the work of my longtime collaborator in the lab Allison Fay, who wanated to create new tools for disocvery biology in mycobacteria, specifically a new sysem for protein localizaton and proximity proteomics.

www.biorxiv.org/content/10.1...
March 25, 2025 at 2:54 PM
Reposted by Pierre Dupuy
Shout-out to @pierredupuy.bsky.social and colleagues!
Excited to share our latest study, where we uncovered a previously unknown bacterial defense system in M. #tuberculosis: effluxosomes — dynamic membrane clusters that coordinate resistance to multiple toxic metals.
shorturl.at/Ek0HD
#MicroSky
March 27, 2025 at 6:09 AM
Reposted by Pierre Dupuy
Comment la bactérie responsable de la tuberculose survit-elle aux attaques des cellules immunitaires ? 🦠
Pierre Dupuy, lauréat d’une bourse postdoctorale Marie-Curie financée par l’UE, revient sur son projet.
@cnrsbiologie.bsky.social @cnrs.fr @isabellesaves.bsky.social @oneyrolles.bsky.social
March 25, 2025 at 9:35 AM
Reposted by Pierre Dupuy
Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Métais, @gclugo.bsky.social, @chrisverollet.bsky.social and all colleagues!
We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell.
Let's dive in👇

shorturl.at/x4Sb5
March 13, 2025 at 6:43 AM