Phil Gross, PhD
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philgrossphd.bsky.social
Phil Gross, PhD
@philgrossphd.bsky.social
Postdoctoral Fellow at NIH Center for Alzheimer’s and Related Dementias. #TDP43 #Organoids #Neuroimmunology Prior: @GeorgetownBGE. Views are my own
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Excited to finally have this published! Out today in @naturecomms.bsky.social, we show that following demyelination in a mouse model of Multiple Sclerosis, treatment of senescent microglia with senolytics leads to improved remyelination. www.nature.com/articles/s41...

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Senescent-like microglia limit remyelination through the senescence associated secretory phenotype - Nature Communications
The impact of senescent cells on remyelination is unknown. Here, the authors show that treatment with senolytics following demyelination enhances remyelination in young, but not aged mice, and these e...
www.nature.com
Reposted by Phil Gross, PhD
We built in the US the best scientific industry in world history and it is dying.

Fixing just the damage done since Jan 20 would take years. Maybe a decade. The program staff, SROs, and brilliant talent is not coming back.
March 20, 2025 at 2:46 AM
Reposted by Phil Gross, PhD
‪Congratulations Phil @philgrossphd.bsky.social and a huge thank you to all the lab members and collaborators for their contributions to our project on the role of senescence in remyelination, which has now been published in @naturecomms.bsky.social! 😀 www.nature.com/articles/s41...
Senescent-like microglia limit remyelination through the senescence associated secretory phenotype - Nature Communications
The impact of senescent cells on remyelination is unknown. Here, the authors show that treatment with senolytics following demyelination enhances remyelination in young, but not aged mice, and these e...
www.nature.com
March 7, 2025 at 3:52 PM
Reposted by Phil Gross, PhD
Check out this exciting work by @philgrossphd.bsky.social in the @jkhuang.bsky.social lab! Thanks for asking us to be a part of it
March 7, 2025 at 2:24 PM
Excited to finally have this published! Out today in @naturecomms.bsky.social, we show that following demyelination in a mouse model of Multiple Sclerosis, treatment of senescent microglia with senolytics leads to improved remyelination. www.nature.com/articles/s41...

1/3
Senescent-like microglia limit remyelination through the senescence associated secretory phenotype - Nature Communications
The impact of senescent cells on remyelination is unknown. Here, the authors show that treatment with senolytics following demyelination enhances remyelination in young, but not aged mice, and these e...
www.nature.com
March 7, 2025 at 1:57 PM
Reposted by Phil Gross, PhD
Very excited that Phil Gross @PSGrossScience @georgetown #IPN #GUBiology has successfully defended his PhD thesis on the role of cellular senescence in CNS remyelination. Next stop a postdoc at the NIH. Congratulations Dr. Gross! 🎉🎉🎉🍾🍾🍾
January 11, 2025 at 10:36 PM