Peter Bradley
@peterbradleyucla.bsky.social
Professor at UCLA studying the opportunistic pathogen Toxoplasma gondii
https://bradleylab.dgsom.ucla.edu
https://bradleylab.dgsom.ucla.edu
Reposted by Peter Bradley
Huge News
Coartem® Baby—1st malaria drug approved for newborns <5 kg
It's a cherry-flavored mix of artemether (rapid parasite clearance) & lumefantrine (long-acting, prevents recrudescence)—dissolves in breast milk and optimized PK/PD for infant metabolism
Not-for-profit launch planned in Africa
Coartem® Baby—1st malaria drug approved for newborns <5 kg
It's a cherry-flavored mix of artemether (rapid parasite clearance) & lumefantrine (long-acting, prevents recrudescence)—dissolves in breast milk and optimized PK/PD for infant metabolism
Not-for-profit launch planned in Africa
First malaria medicine for newborn babies and young infants
Coartem® (artemether-lumefantrine) Baby has become the first malaria treatment approved for newborn babies and young infants.
www.mmv.org
July 9, 2025 at 6:14 PM
Huge News
Coartem® Baby—1st malaria drug approved for newborns <5 kg
It's a cherry-flavored mix of artemether (rapid parasite clearance) & lumefantrine (long-acting, prevents recrudescence)—dissolves in breast milk and optimized PK/PD for infant metabolism
Not-for-profit launch planned in Africa
Coartem® Baby—1st malaria drug approved for newborns <5 kg
It's a cherry-flavored mix of artemether (rapid parasite clearance) & lumefantrine (long-acting, prevents recrudescence)—dissolves in breast milk and optimized PK/PD for infant metabolism
Not-for-profit launch planned in Africa
Reposted by Peter Bradley
Check out the gorgeous green eyes on this Shortfin Lionfish (Dendrochirus brachypterus)
June 21, 2025 at 5:16 AM
Check out the gorgeous green eyes on this Shortfin Lionfish (Dendrochirus brachypterus)
Nice work from my former graduate student Amara (now postdoc at Stanford) on a new effector protein in Toxoplasma www.molbiolcell.org/doi/epdf/10....
Proteolytic processing and host nuclear targeting of the novel effector GRA84 in Toxoplasma gondii
www.molbiolcell.org
June 5, 2025 at 8:46 PM
Nice work from my former graduate student Amara (now postdoc at Stanford) on a new effector protein in Toxoplasma www.molbiolcell.org/doi/epdf/10....
Reposted by Peter Bradley
Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research.
Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...
Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...
June 2, 2025 at 5:57 PM
Make open access to tools and data part of your annual giving by making a tax deductible donation to @veupathdb.org. 💙This resource simplifies and supercharges global infectious disease research.
Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...
Need more reasons to support VEuPathDB? Here's a short list: veupathdb.org/veupathdb/ap...
Reposted by Peter Bradley
"In California, solar generation could finally surpass gas this year."
Actually, the probability that solar surpasses gas in 2025 is high!
Gas fell from 50% of CA's electricity in January 2024 to 40% in January 2025, and solar rose from 20% to 28%.
www.canarymedia.com/articles/sol...
#energysky
Actually, the probability that solar surpasses gas in 2025 is high!
Gas fell from 50% of CA's electricity in January 2024 to 40% in January 2025, and solar rose from 20% to 28%.
www.canarymedia.com/articles/sol...
#energysky
April 16, 2025 at 7:46 PM
"In California, solar generation could finally surpass gas this year."
Actually, the probability that solar surpasses gas in 2025 is high!
Gas fell from 50% of CA's electricity in January 2024 to 40% in January 2025, and solar rose from 20% to 28%.
www.canarymedia.com/articles/sol...
#energysky
Actually, the probability that solar surpasses gas in 2025 is high!
Gas fell from 50% of CA's electricity in January 2024 to 40% in January 2025, and solar rose from 20% to 28%.
www.canarymedia.com/articles/sol...
#energysky
Reposted by Peter Bradley
Prediction:
Today (4/9/25) registered the greatest ill gotten gains from insider trading in history.
Today (4/9/25) registered the greatest ill gotten gains from insider trading in history.
April 10, 2025 at 3:44 AM
Prediction:
Today (4/9/25) registered the greatest ill gotten gains from insider trading in history.
Today (4/9/25) registered the greatest ill gotten gains from insider trading in history.
Reposted by Peter Bradley
Vaccines. 💪🏻💪🏻
And yet Joe Rogan puts guests on who say "Vaccines aren't actually responsible for the reduction in infectious diseases.”
March 30, 2025 at 8:23 PM
Vaccines. 💪🏻💪🏻
Great turn out for Stand up for Science rally in Westwood yesterday
March 9, 2025 at 4:16 AM
Great turn out for Stand up for Science rally in Westwood yesterday
Reposted by Peter Bradley
Nice turnout and great weather at the Stand Up For Science rally in Los Angeles by UCLA
March 7, 2025 at 10:29 PM
Nice turnout and great weather at the Stand Up For Science rally in Los Angeles by UCLA
Protest at Space X in Hawthorne CA today. Seemed like 2-3k people showed up to me
March 2, 2025 at 4:11 AM
Protest at Space X in Hawthorne CA today. Seemed like 2-3k people showed up to me
Lots of crappy news out there recently - but at least my worms are happy....
February 17, 2025 at 12:51 AM
Lots of crappy news out there recently - but at least my worms are happy....
Reposted by Peter Bradley
Amazing! ‘Twinkling Toxoplasma’ Tree (image by Kseniia Bondarenko) wins 2024 Festive Science Image Competition.
December 3, 2024 at 5:45 PM
Amazing! ‘Twinkling Toxoplasma’ Tree (image by Kseniia Bondarenko) wins 2024 Festive Science Image Competition.
Reposted by Peter Bradley
'For scientists the network is starting to look like home. Academic institutions, scientific journals and conferences, and international organizations such as the World Health Organization have established a presence there in recent days.'
www.science.org/content/arti...
www.science.org/content/arti...
Like ‘old Twitter’: The scientific community finds a new home on Bluesky
After recent changes to Elon Musk’s X, a gradual migration turns into a stampede
www.science.org
November 21, 2024 at 5:49 AM
'For scientists the network is starting to look like home. Academic institutions, scientific journals and conferences, and international organizations such as the World Health Organization have established a presence there in recent days.'
www.science.org/content/arti...
www.science.org/content/arti...
Reposted by Peter Bradley
Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]
www.fiercebiotech.com/research/rep...
www.fiercebiotech.com/research/rep...
Report: Every dollar of NIH research funding doubles in economic returns
Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an
www.fiercebiotech.com
November 17, 2024 at 11:56 PM
Research funded by NIH generated $2.46 in economic activity for every $1 of funding in 2023 [a total of $92.9 billion]
www.fiercebiotech.com/research/rep...
www.fiercebiotech.com/research/rep...
Congratulations to @petersmback.bsky.social on fantastic work on the Toxoplasma alveolin network and its interactions via UAA photocrosslinking. A really detailed study with great help from the Ward and Zhou labs! journals.plos.org/plosbiology/...
Alveolin proteins in the Toxoplasma inner membrane complex form a highly interconnected structure that maintains parasite shape and replication
Picomplexan parasites require specialized structures like the inner membrane complex to invade host cells and replicate. This study shows that the alveolin protein IMC6 is crucial for maintaining cell...
journals.plos.org
September 12, 2024 at 6:50 PM
Congratulations to @petersmback.bsky.social on fantastic work on the Toxoplasma alveolin network and its interactions via UAA photocrosslinking. A really detailed study with great help from the Ward and Zhou labs! journals.plos.org/plosbiology/...
Nice work out from my PhD student Rebecca on daughter cell assembly in Toxoplasma gondii journals.plos.org/plospathogen...
BCC0 collaborates with IMC32 and IMC43 to form the Toxoplasma gondii essential daughter bud assembly complex
Author summary Toxoplasma gondii is an obligate intracellular parasite that causes severe and even fatal disease in congenitally infected neonates and the immunocompromised. The parasite replicates us...
journals.plos.org
July 19, 2024 at 1:00 AM
Nice work out from my PhD student Rebecca on daughter cell assembly in Toxoplasma gondii journals.plos.org/plospathogen...
Terrific work from my student Justin Quan (justinquan.bsky.social) on the TBC domain proteins in Toxoplasma gondii. journals.plos.org/plosbiology/...
Systematic characterization of all Toxoplasma gondii TBC domain-containing proteins identifies an essential regulator of Rab2 in the secretory pathway
Toxoplasma gondii regulates vesicle trafficking by secreting Rab GTPases from specialised organelles. This study characterizes all Tre2-Bub2-Cdc16 (TBC) domain-containing proteins in T. gondii, identi...
journals.plos.org
May 9, 2024 at 4:52 PM
Terrific work from my student Justin Quan (justinquan.bsky.social) on the TBC domain proteins in Toxoplasma gondii. journals.plos.org/plosbiology/...
Excellent work from my PhD student Rebecca was highlighted in The Scientist www.the-scientist.com/news/punctua...
February 1, 2024 at 8:46 PM
Excellent work from my PhD student Rebecca was highlighted in The Scientist www.the-scientist.com/news/punctua...
Reposted by Peter Bradley
Cat parasite <i>Toxoplasma</i> tricked to grow in a dish
Cat parasite Toxoplasma tricked to grow in a dish
Cat-only life-cycle stage cultured in vitro, and the mysterious giant proteins that might turn bacteria into killers.
www.nature.com
December 13, 2023 at 7:44 PM
Cat parasite <i>Toxoplasma</i> tricked to grow in a dish
Congrats to my PhD student Rebecca for very nice work on the essential daughter bud assembly protein IMC43 in T. gondii. journals.plos.org/plospathogen...
Identification of IMC43, a novel IMC protein that collaborates with IMC32 to form an essential daugh...
Author summary Toxoplasma gondii is an obligate intracellular parasite that causes disease in immunocompromised individuals and congenitally infected neonates. Toxoplasma replicates using a unique pro...
journals.plos.org
October 4, 2023 at 6:44 PM
Congrats to my PhD student Rebecca for very nice work on the essential daughter bud assembly protein IMC43 in T. gondii. journals.plos.org/plospathogen...