Allen Cheng
@peripatetical.bsky.social
Infectious diseases physician, epidemiologist. Melbourne, Australia.
Pinned
Allen Cheng
@peripatetical.bsky.social
· Nov 16
Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky
Congratulations to Steve Tong, Josh Davis and the huge SNAP team (including Monash Health). Clear outcome that cefazolin is less nephrotoxic than flucloxacillin for MSSA, and pencillin is better for PSSA. @steventong.bsky.social @gurujosh.bsky.social
@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025
fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA
April 13, 2025 at 10:37 AM
Congratulations to Steve Tong, Josh Davis and the huge SNAP team (including Monash Health). Clear outcome that cefazolin is less nephrotoxic than flucloxacillin for MSSA, and pencillin is better for PSSA. @steventong.bsky.social @gurujosh.bsky.social
Reposted by Allen Cheng
Cool paper from Florian Kramer & colleagues about a novel feature of circulating H5N1 clade 2.3.4.4. These viruses have a longer stalk in their neuraminidase (NA) enzyme, a key viral protein. This was not seen in past H5N1 strains (2002-2019)
Why does it matter?🧪
journals.asm.org/doi/10.1128/...
Why does it matter?🧪
journals.asm.org/doi/10.1128/...
Clade 2.3.4.4b H5N1 neuraminidase has a long stalk, which is in contrast to most highly pathogenic H5N1 viruses circulating between 2002 and 2020 | mBio
While the truncated version of the N1 neuraminidase stalk domain may be associated
with increased virulence in poultry, the long version of the stalk domain has been
associated with increased transmis...
journals.asm.org
March 1, 2025 at 12:40 PM
Cool paper from Florian Kramer & colleagues about a novel feature of circulating H5N1 clade 2.3.4.4. These viruses have a longer stalk in their neuraminidase (NA) enzyme, a key viral protein. This was not seen in past H5N1 strains (2002-2019)
Why does it matter?🧪
journals.asm.org/doi/10.1128/...
Why does it matter?🧪
journals.asm.org/doi/10.1128/...
Looks like PubMed is down - not sure if this is a temporary outage or something more sinister. Europe PMC is an alternative search engine for medical literature that is publicly accessible. europepmc.org
Europe PMCHome - Europe PMC
Europe PMC is an archive of life sciences journal literature.
europepmc.org
March 2, 2025 at 10:45 AM
Looks like PubMed is down - not sure if this is a temporary outage or something more sinister. Europe PMC is an alternative search engine for medical literature that is publicly accessible. europepmc.org
Reposted by Allen Cheng
Great list @absteward.bsky.social! Mine is coming soon (limited to 10)
🔥🔥 NEW 🔥🔥
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...
Year In Review: Top Infectious Diseases Articles From 2024
In this article a selection of notable peer-reviewed publications from 2024 are provided. Article Selection by: Bassam Ghanem, Pharm.D., MS, BCPS Article Construction by: Timothy P. Gauthier, Pharm.D....
www.idstewardship.com
December 12, 2024 at 10:28 AM
Great list @absteward.bsky.social! Mine is coming soon (limited to 10)
Paul Sax's "oh wow" moments in HIV: AZT during pregnancy reduces vertical transmission; triple ARVs improve survival; integrase inhibitors as effective salvage therapy; PrEP is very effective; undetectable = untransmissible and now 6 monthly lenacapravir PReP is 100% effective
With the publication of PURPOSE 2 for PrEP in @nejm.org, and the stellar results, I wonder what’s going to happen once it gets approved for this indication. Should be interesting, to say the least! blogs.jwatch.org/hiv-id-obser...
Who's Going to Get Lenacapavir for HIV Prevention?
At the International AIDS Conference this past summer, Dr. Linda-Gail Bekker brought down the house presenting the results of the PURPOSE 1 trial of twice-yearly injectable lenacapavir for prevention ...
blogs.jwatch.org
December 12, 2024 at 2:41 AM
Paul Sax's "oh wow" moments in HIV: AZT during pregnancy reduces vertical transmission; triple ARVs improve survival; integrase inhibitors as effective salvage therapy; PrEP is very effective; undetectable = untransmissible and now 6 monthly lenacapravir PReP is 100% effective
Five years ago (1 Dec 2019), the first person became unwell in a case cluster of a new infection that we now know as COVID-19. pmc.ncbi.nlm.nih.gov/articles/PMC...
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). We report the epidemiological, clinical, laboratory, and radiologica...
pmc.ncbi.nlm.nih.gov
December 1, 2024 at 10:00 PM
Five years ago (1 Dec 2019), the first person became unwell in a case cluster of a new infection that we now know as COVID-19. pmc.ncbi.nlm.nih.gov/articles/PMC...
Congratulations to the BALANCE group on the trial published in NEJM today. This trial tested 7 vs 14 days of antibiotics for bloodstream infection. #IDSky www.nejm.org/doi/full/10....
Antibiotic Treatment for 7 versus 14 Days in Patients with Bloodstream Infections | NEJM
Bloodstream infections are associated with substantial morbidity and mortality. Early,
appropriate antibiotic therapy is important, but the duration of treatment is uncertain.
In a multicenter, non...
www.nejm.org
November 21, 2024 at 2:02 AM
Congratulations to the BALANCE group on the trial published in NEJM today. This trial tested 7 vs 14 days of antibiotics for bloodstream infection. #IDSky www.nejm.org/doi/full/10....
Reposted by Allen Cheng
Lessons from practice for immunocompromised hosts by Dr Ai Li Yeo and A/Prof Claire Dendle
#ForbesWeek #IDSky
1. There can be more than two pathologies in immunocompromised patients
#ForbesWeek #IDSky
1. There can be more than two pathologies in immunocompromised patients
November 15, 2024 at 7:21 AM
Lessons from practice for immunocompromised hosts by Dr Ai Li Yeo and A/Prof Claire Dendle
#ForbesWeek #IDSky
1. There can be more than two pathologies in immunocompromised patients
#ForbesWeek #IDSky
1. There can be more than two pathologies in immunocompromised patients
Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky
November 16, 2024 at 12:03 AM
Allen Yung's Golden Rules of ID. Copied over from the Other Place for @kottonnelson.bsky.social #IDSky