Oskar Staufer
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ostaufer.bsky.social
Oskar Staufer
@ostaufer.bsky.social
Emmy Noether Research Group Leader Immuno-Materials @ Leibniz INM and @ MaxPlanck Bristol | Combining SynBio and immunology with synthetic cells, biophysics, organoids
Reposted by Oskar Staufer
Building tissues from the bottom up!

In Advanced Healthcare Materials @wiley.com, @ostaufer.bsky.social and co-authors show synthetic cells forming lymph-node-like tissues that host immune cells -towards building synthetic organs.

doi.org/10.1002/adhm...

#academicsky 🧪
Synthetic Cell‐Based Tissues for Bottom‐Up Assembly of Artificial Lymphatic Organs
Synthetic cells have emerged as a novel biomimetic approach for fundamental research and therapeutic interventions. T cell activating synthetic cells are able to form 3D tissue-like structures by sel....
doi.org
October 29, 2025 at 9:57 AM
Reposted by Oskar Staufer
🌱 New beginnings, fresh faces!
As our pilot phase wraps up, the school is ready to grow and thrive. We’re thrilled to welcome 18 new fellows to the #MatterToLife Faculty 🎉 Each brings exciting perspectives from across interdisciplinary research. mattertolife.maxplanckschools.org/355008/new-f...
New Faculty Members from October 2025
Matter to Life welcomes 18 new Fellows, enhancing innovative research and mentorship opportunities for PhD candidates starting this October.
mattertolife.maxplanckschools.org
October 1, 2025 at 2:50 PM
Reposted by Oskar Staufer
Congrats to Saarbrücken researchers!

Prof. Karin Jacobs, Prof. Franziska Lautenschläger & @ostaufer.bsky.social join the Max Planck School Matter to Life as Fellows, strengthening biophysics & soft matter research in Germany.

#academicsky #science
September 18, 2025 at 7:54 PM
Reposted by Oskar Staufer
Apply now to join my group as a postdoctoral Fellow at @imperialcollege

We are supporting applications for:
- Imperial College Research Fellowship
-Marie Skłodowska-Curie Postdoctoral Fellowships

Get in touch: continilab.com
#SoftMatter, #CellMimicry #polymerchemistry
May 30, 2025 at 3:17 PM
Reposted by Oskar Staufer
New paper from the Staufer Lab - Immuno Materials, a group that seeks to build immunity from the bottom-up
June 2, 2025 at 8:39 AM
Excited to share our new @pnas.org paper! We used reconstitution approaches and synthetic cells to uncover what drives bispecific T cell engagers efficiency. This helps future #immunotherapy design and demonstrates the potential of synthetic cells in #immunoengineering:
www.pnas.org/doi/10.1073/...
Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency | PNAS
Bispecific T cell engagers (TcEs) link T cell receptors to tumor-associated antigens on cancer cells, forming cytotoxic immunological synapses (IS)...
www.pnas.org
May 31, 2025 at 8:32 AM
Reposted by Oskar Staufer
New paper out! Would you like to fluorescently label the plasma membrane in live, fixed or permeabilized cells? I tested different lipid structures and labelling approaches to decide what makes a good membrane labelling probe for such imaging experiments!
www.biorxiv.org/content/10.1...
Plasma membrane labelling efficiency, internalization and partitioning of functionalized fluorescent lipids as a function of lipid structure
Labeling the plasma membrane for advanced imaging remains a significant challenge. For time-lapse live cell imaging, probe internalization and photobleaching are major limitations affecting most membr...
www.biorxiv.org
May 13, 2025 at 12:07 PM
Very happy to have you onboard Marion!
We are super excited to announce that Marion has joined our #MSCA-DN to work in the @ostaufer.bsky.social lab.

The project will focus on the development of #SyntheticCell models that mimic #Age-RelatedDiseases. More details: www.comeincell.org/dc04-synthet...

Welcome Marion! #HorizonEurope
April 29, 2025 at 4:52 PM
Reposted by Oskar Staufer
We have an exciting new PhD opportunity!

If you are fsacinated by proteins and their dynamics and want to engineer them to develop new molecular tools: apply now!
We are a young and dynamic team combining state-of-the-art laboratory and bioinformatics approaches.
Please share.
April 1, 2025 at 11:52 AM
Reposted by Oskar Staufer
#newPI and time is running.

It has already been a month since I officially joined the University of Warwick as Assistant Professor. I am excited to announce and build the Fluorescence and Membrane Dynamics (FMD) Lab:

warwick.ac.uk/fac/sci/med/...
April 22, 2025 at 7:37 PM
Reposted by Oskar Staufer
Material Minds 10 is out!
We talk to Phil Egberts, Prof. at @ucalgary.bsky.social and INM alum. He shares how his journey in materials science began with salt crystals, led him to Germany, and eventually landed in the world of friction & lubrication.
Full episode here - youtu.be/Me1rwvf9-XQ?...
April 1, 2025 at 9:43 PM
Reposted by Oskar Staufer
Zeiss has released its light field microscope!

zeiss.wistia.com/medias/otnxx...
Lightfield 4D: Instant volumetric imaging of a beating embryonic zebrafish heart
Courtesy of Stone Elworthy and Emily Noël, School of Biosciences, University of Sheffield, UK
zeiss.wistia.com
March 6, 2025 at 3:26 PM
Reposted by Oskar Staufer
📣NEW PAPER ALERT ⚠️

Finally out in Nature Communications, after unfortunately spending almost 1 year under review at Nature Materials 🤐
But very very pround of this work that was spearheaded by extremely talented PhD student Moritz Weck:
www.nature.com/articles/s41...
Fully addressable designer superstructures assembled from one single modular DNA origami - Nature Communications
Methods for creating large DNA assemblies with low cost and enhanced structural control are of interest. Here, the authors report moDON (modular DNA origami nanostructure) that combines two approaches...
www.nature.com
February 12, 2025 at 3:03 PM
Reposted by Oskar Staufer
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs).
www.nature.com/articles/s41...
@ibecbarcelona.eu
February 7, 2025 at 11:46 AM
Reposted by Oskar Staufer
🚨Three weeks left to apply for this #fullyfunded #PhDopportunity in my group! 🚨
Are you an UK-Home student interest in #SyntheticCells science?
We are looking for you!

@imperialcollegeldn.bsky.social @imperiallifesci.bsky.social @imperialsci.bsky.social
Please Share! 🚨 #FullyFunded #PhDopportunity for UK-home student 🚨

🔬Are you interested in designing dynamic synthetic cells that mimic essential life-like functions?

Join my group at @imperialsci.bsky.social @imperialcollegeldn.bsky.social ! #cellmimicry #FindAPhD

findaphd.com/phds/project/e…
January 24, 2025 at 1:52 PM
Reposted by Oskar Staufer
More than 40 percent of #postdocs leave academia. Those who landed a coveted faculty position were more likely to have had a highly cited paper, changed their research topic between their #PhD and postdoc, or moved abroad after receiving their doctorate. www.pnas.org/doi/10.1073/... @pnas.org
More than 40% of postdocs leave academia, study reveals
Publishing highly cited papers helps postdoctoral researchers to land a faculty job.
www.nature.com
January 23, 2025 at 1:49 PM
Reposted by Oskar Staufer
🔔Upcoming deadline!🔔

January 27 is the last day to submit applications to the MBL's 2025 Physiology Course. This seven-week lab course has educated generations of leading biologists and fostered groundbreaking discoveries.

Learn more: bit.ly/3BZSj9c
#ScienceStartsHere
January 13, 2025 at 2:48 PM
Reposted by Oskar Staufer
🇩🇪In unserem nächsten #PoLComic geht es darum, wie hydrophobe und hydrophile Moleküle unseren Zellen helfen, richtig zu funktionieren.

Vollständige Version hier: physics-of-life.tu-dresden.de/news-events/...

Comic von Jon Chad: www.jonchad.com
#Biophysik #Wissenschaftskommunikation #Forschung
January 22, 2025 at 5:02 PM
Hello BlueSky 👋 Happy to start here by sharing our lastest review on synthetic cells in tissue engineering. Great concepts presented by the amazing PhD students Anna Burgstaller and Sara Madureira

www.sciencedirect.com/science/arti...

#SynCells #tissueengineering #biomimetics #biomaterials #SynBio
Synthetic cells in tissue engineering
Tissue functions rely on complex structural, biochemical, and biomechanical cues that guide cellular behavior and organization. Synthetic cells, a pro…
www.sciencedirect.com
January 22, 2025 at 12:25 PM