orchardlab.bsky.social
@orchardlab.bsky.social
Reposted
Faculty search announcement 2025: Tenure-Track Assistant Professor in Microbiology at UT Southwestern. We seek candidates working in microbial pathogenesis (some preference may be given to bacterial pathogens). Come join our community! (1/5) www.utsouthwestern.edu/departments/...
August 18, 2025 at 2:31 PM
Reposted
Valerie Rodriguez Irizarry’s tour de force paper on murine norovirus adaptation/egress is now out in peer-reviewed form ‪@plosbiology.org‬. It highlights the power of forward genetics in virology research. 🧵 1/10 journals.plos.org/plosbiology/...
June 25, 2025 at 1:36 PM
Excited to share the work of Mikayla Olson in the lab making a replication competent reporter virus for murine norovirus. journals.plos.org/plospathogen...
Development of a replication competent murine norovirus reporter system
Author summary Colloquially known as “the stomach bug,” human norovirus is a leading cause of foodborne illness worldwide. Despite its prevalence, there are no approved therapeutics or vaccines agains...
journals.plos.org
May 27, 2025 at 8:24 PM
Reposted
Excited to have this story published @plosbiology.org. We were surprised to find lipids are important for entry of a non-enveloped virus and that TMEM30a is important for enteric infection of murine norovirus!
Norovirus tropism depends partly on entry receptors, but what is the role of cellular #lipids? @orchardlab.bsky.social &co show that TMEM30a-mediated lipid asymmetry is crucial for murine #norovirus infection, influencing membrane fluidity, viral binding & entry @plosbiology.org 🧪 plos.io/4409MtI
April 23, 2025 at 2:13 PM