Open Medicine Foundation (OMF)
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openmedf.bsky.social
Open Medicine Foundation (OMF)
@openmedf.bsky.social
4.3K followers 670 following 640 posts
OMF is fundraising to support open, collaborative research to find effective treatments and a cure for ME/CFS, Long COVID, and related diseases.
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openmedf.bsky.social
With just a few hours left in 2025, you have a unique opportunity to make a difference with a year-end gift. 🔗Donate now: www.omf.ngo?form=donatenow

ICYMI: Director interviews, OMF Journal Club, Science Wednesdays & an upcoming community webinar: www.omf.ngo/year-end-202....
A hand holding a paper labeled “Hope” in sunlight, with text reading “End the year with hope. Last chance to make a difference in 2025,” and OMF branding.
December 31, 2025 at 3:22 PM
openmedf.bsky.social
⏳ Only 2 Days Left to Donate in 2025! 👉 Donate today: ow.ly/jNMx50XQmj6.

As 2025 draws to a close, we want to take a moment to reflect on the progress we’ve made together.🔬 Check out our 2025 Publications and Preprint Overview: ow.ly/YTQT50XQmj4.
Blue-toned lab image with a microscope and glassware. The OMF Hope logo appears in the top left, and a banner reads “2025 Publications and Preprints.”
December 30, 2025 at 4:05 PM
openmedf.bsky.social
Because of our community, 2025 moved the field forward. Since 2012: $60M+ raised, 76 projects, 53 publications.

With just a few days left in 2025, will you consider making a gift? A year-end gift keeps research moving. Donate hope today👉 www.omf.ngo?form=donatenow
Key highlights from 2025: 40 active research projects underway; 16 new scientific publications and one preprint; StudyME registry with over 14,500 participants supporting 21 studies worldwide; launch of BioQuest, the largest biomarker discovery study in ME/CFS research; progress in the Life Improvement Trial (LIFT); and release of a Clinical Care Guide for ME/CFS and Long COVID through the Medical Education Resource Center.
December 27, 2025 at 4:39 PM
openmedf.bsky.social
Rachel Riggs’ long-awaited cookbook, In Good Health, is here for food lovers who crave simple, flavorful, and nutrient-rich cooking. The first year’s proceeds from the book will go to OMF.

Learn more and explore the Dark Chocolate Tahini Truffles Recipe: ow.ly/hyWf50XNHgn
Dark chocolate tahini truffles dusted with cocoa powder on a white plate. This image is the cover of a book titled "In Good Health" by Rachel Riggs. It features a colorful arrangement of grilled vegetables, including asparagus, onions, and radishes, along with a bowl of dipping sauce.
December 23, 2025 at 3:05 PM
openmedf.bsky.social
The citric acid (TCA) cycle is a series of chemical reactions in the mitochondria. At OMF’s CRC at Stanford University, Dr. Ron Davis’ team is investigating alterations to the TCA cycle in #pwME, specifically a hypothesis called the itaconate shunt.

🔗 Read more about this work👉 ow.ly/fkNN50XKRx6
An illustrated mitochondrion labeled “TCA Cycle,” shown in bright blue and green tones. A “Science Wednesdays” banner appears at the bottom, with the OMF Hope logo in the lower right corner.
December 17, 2025 at 2:55 PM
openmedf.bsky.social
Honor Your Loved Ones with the Gift of Hope and Research ❤️ To make a tribute gift:

1️⃣ Visit ow.ly/kaQP50XKjNk
2️⃣ Select "Dedicate this donation"
3️⃣ In the comments section, let us know who we should notify about your gift
Holiday collage with wooden house ornaments, a cozy hot chocolate scene, and hands holding a paper that says “HOPE.”
December 16, 2025 at 4:09 PM
openmedf.bsky.social
ICYMI: Dr. Armstrong & the team recently published a paper on their work looking at which genes were most impactful to metabolites in #MECFS and which were most impactful in controls.

👉 Watch a short video update : ow.ly/ZW4M50XJGr2
December 15, 2025 at 5:44 PM
openmedf.bsky.social
Thank you to our OMF community for making this year's Triple Giving November record-breaking. We are thrilled to share that our Triple Giving November campaign raised over $3 million this year! Because of the remarkable generosity of our leadership donors every gift was tripled.
An announcement graphic with blue balloons and confetti on a light background. The text reads “Over $3M Raised” in large blue letters, with “Thank You” written below in a script font.
December 12, 2025 at 5:50 PM
openmedf.bsky.social
Stratification is a fancy way of saying that participants in a research study are divided into subgroups, or stratified, based on specific characteristics (like sex or age). It helps researchers determine how those characteristics influence the results.

Learn more👉 www.omf.ngo/what-is-stra...
Graphic for OMF’s Science Wednesdays featuring the topic ‘Stratification,’ with medical icons and lab equipment in the background.
December 10, 2025 at 3:58 PM
openmedf.bsky.social
🔬Help advance #MECFS and #LongCOVID research by joining OMF’s StudyME, a free global participant registry that connects you with researchers conducting studies in these areas. Healthy volunteers are needed too!

👉 Sign up today: www.omf.ngo/studyme/

#UnitedForME #MECFSresearch #POTS #pwME #pwLC
Graphic with the StudyME logo, showing a blue interconnected globe and the text ‘Accelerate Research – Join OMF StudyME Registry,’ along with the OMF logo in the corner.
December 9, 2025 at 2:10 PM
openmedf.bsky.social
Dr. Chris Armstrong, the Director of OMF’s Melbourne ME/CFS Collaboration, and his team recently published a paper on their work looking at which genes were most impactful to metabolites in #MECFS and which were most impactful in controls.

👉Read more: ow.ly/ast150XG0rz.
Graphic announcing “New Publication—Exploring a genetic basis for the metabolic perturbations in ME/CFS using UK Biobank.” Includes a “Learn more” button and a photo of Chris Armstrong in a suit at a symposium.
December 8, 2025 at 10:11 PM
Reposted by Open Medicine Foundation (OMF)
precisionlife.bsky.social
New myalgic encephalomyelitis (ME, also known as ME/CFS) genetics study reveals 250+ core genes, shared mechanisms with long COVID, and dozens of drug repurposing opportunities. This would not have been possible without the thousands of people with ME who contributed their data.
Thank you.
December 4, 2025 at 8:00 AM
openmedf.bsky.social
Physiological response is an involuntary, automatic, internal process that is stimulated by something like stress or infection. Symptoms are how a person experiences those internal changes in a clinically observable way. In #MECFS research, it’s important to monitor both.
The image features a large clear lightbulb placed on a wooden surface. Inside the bulb is an abstract illustration of a brain, drawn with glowing white circuit-like lines. At the bottom, on a blue banner, the text reads:SCIENCE WEDNESDAYS, PHYSIOLOGICAL RESPONSE VS. SYMPTOMS
December 3, 2025 at 5:43 PM
openmedf.bsky.social
OMF’s Directors talk about their overarching hypotheses of the disease. They also discuss research findings that complement or validate each other, including the underlying mechanism of #PEM, treatment strategies, & more.

👉 ow.ly/IOv850XASO9
Seven portraits of researchers side by side above the text: “The Intersections of OMF’s Research Portfolio.” From left to right: Jonas Bergquist, RonDavis, David Systrom, Chris Armstrong, Wenzhing Xiao, Alain Moreau and Danielle Meadows.
December 2, 2025 at 8:00 PM
openmedf.bsky.social
In today’s video interview with all of OMF’s directors, they discuss the connections between their research, and Dr. Meadows shares a visual representation of some of those connections. 🧩

👉 Watch the interview and TRIPLE your impact today: www.omf.ngo/interview-wi...
The graphic shows how a failure to recover from triggers and risk factors (top left) leads to a complex web of dysregulated systems, and the interactions between these systems yield the disease phenotype that can vary from person to person.
December 2, 2025 at 5:26 PM
openmedf.bsky.social
✨Last Chance to Triple Your Impact! In this interview, all of OMF’s Directors talk about how their overarching hypotheses of #MECFS might explain how symptoms look different in different people.

🔗 Watch now and support OMF's research: www.omf.ngo/interview-wi...

#GivingTuesday
December 2, 2025 at 4:35 PM
openmedf.bsky.social
⏰ 3x Match Ends Today! Today is #GivingTuesday, marking the final hours of our Triple Giving November campaign!

There are just a FEW HOURS LEFT to have your donation tripled —up to $1 million! 💙 Give today and help make a difference: www.omf.ngo?form=donate-...

#pwME #pwLC #MECFS #LongCOVID
The image shows all OMF Directors, Maureen Hanson & Linda Tannenbaum. At the bottom, there’s a blue overlay with white text that reads: “Last Day to Triple Your Impact” Below that is the Giving Tuesday logo with the red heart-shaped “V.”
December 2, 2025 at 3:39 PM
openmedf.bsky.social
It’s time to reduce the suffering and symptom severity faced by people with #MECFS & #LongCOVID. Your donation of any amount supports collaborative research to find answers.

Let's make these final hours count. Donate today to have your gift matched 3x: www.omf.ngo?form=donate-...
Quote from Emily: “Living in constant pain is unbearable. I support OMF because their research provides hope for people like me suffering from ME/CFS and Long COVID.” In the background is a dark room with light filtering through a lace-covered window on the left.
December 1, 2025 at 10:01 PM
openmedf.bsky.social
Only 48 hours left to make your gift count 3x ⏳✨

Triple Giving November is your chance to help accelerate research into #MECFS and #LongCOVID. Every donation is tripled through December 2 (up to $1M). There’s still time!

💙 Donate today: ow.ly/kUgC50XA0Mb
Estelle holds a white sign with black text that reads: “ME/CFS is a profound loss of identity. It is watching most of the things we once held dear growing further out of reach.” Below the photo, on a blue background, large white text reads: “48 hours left! Make your gift count 3x.Donate today: www.omf.ngo.”
December 1, 2025 at 2:31 PM
openmedf.bsky.social
💙 ONLY 4 DAYS LEFT of Triple Giving November! Donate now for a 3x match: ow.ly/6vpR50XztJr

ICYMI: In this interview, Dr. Jonas Bergquist and Dr. Alain Moreau talk about their main ideas behind #MECFS. Watch the interview 👉 ow.ly/U4cg50XztJq
On the left is Dr. Moreau smiling and pointing to a colorful scientific poster filled with charts and text. On the right is Dr. Bergquist wearing a white lab coat and blue shirt. In the center overlaid text reads INTERVIEW.
November 29, 2025 at 4:32 PM
openmedf.bsky.social
Randomization, in the context of clinical research, is the process in which you associate a probability with being assigned to a treatment group. 3 major types of randomization are simple, restricted & adaptive.

Learn more about randomization & OMF’s LIFT: www.omf.ngo/randomization/
The image shows Dr. Systrom wearing a white medical coat. He has grey hair, styled back, and a warm, professional expression. The design includes the title “Science Wednesdays” at the top and the word “Randomization” at the bottom.
November 26, 2025 at 3:59 PM
Reposted by Open Medicine Foundation (OMF)
mecfsskeptic.bsky.social
8) You can support OMF's work by donating using this form:
www.omf.ngo/?form=do...

All donations to OMF are tripled until December 2, 2025.

OMF Home - Open Medicine Foundation
ME/CFS & Long COVID are life-altering illnesses. Together, we can move research further, faster.
www.omf.ngo
November 26, 2025 at 9:34 AM
Reposted by Open Medicine Foundation (OMF)
mecfsskeptic.bsky.social
7) The video also includes insights from another OMF director, Dr. Wenzhong Xiao, who comments about current data and exploring treatment options, including supplements.

Link:
An Interview with Chris Armstrong, PhD and Wenzhong Xiao, PhD
In an interview with Dr. Chris Armstrong and Dr. Wenzhong Xiao, two of OMF’s Directors, they talk about what they think is going on in ME/CFS, including differences in producing energy and the immune and central nervous systems being out of balance. All donations to OMF are TRIPLED until December 2
www.youtube.com
November 26, 2025 at 9:34 AM
Reposted by Open Medicine Foundation (OMF)
mecfsskeptic.bsky.social
1) In this new @OpenMedF video, Dr. Chris Armstrong explains his main hypothesis of ME/CFS.

He suspects there is an inefficiency in producing ATP (energy), but this isn’t only about mitochondria (the engines), but also about the fuel they get...
November 26, 2025 at 9:33 AM
openmedf.bsky.social
⏳There’s only ONE WEEK LEFT to triple your impact. Every dollar you donate to OMF will be TRIPLED—up to $1 million—through December 2, 2025!

Act now before the match runs out! Donate hope 👉 www.omf.ngo?form=donate-....
OMF Triple Giving November graphic with the message “Time is running out—one week left” above a teal twin‑bell alarm clock.
November 25, 2025 at 7:19 PM