Open Medicine Foundation (OMF)
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Open Medicine Foundation (OMF)
@openmedf.bsky.social
4.3K followers 670 following 590 posts
OMF is fundraising to support open, collaborative research to find effective treatments and a cure for ME/CFS, Long COVID, and related diseases.
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Open Medicine Foundation (OMF) @openmedf.bsky.social · 5d
🌍 People worldwide used their limited energy to finish “ME/CFS is…” Their voices show the challenges, losses & urgent need for change. Thanks to matching donors, every gift to OMF is tripled up to $500K!

👉 Donate: www.omf.ngo?form=donate-....

#mecfs #pwME #mecfsresearch
openmedf.bsky.social
As part of our Triple Giving November campaign, we’re pleased to share a video interview with Dr. Ron Davis and Dr. David Systrom.

Together, they discuss how problems with oxygen supply and energy production may underlie #MECFS.

🎥 Learn more and watch the video: www.omf.ngo/ron-davis-an....
November 11, 2025 at 3:27 PM
openmedf.bsky.social
✨This November, your generosity can have triple the impact. Every dollar donated to OMF is matched 3x through December 2, turning one gift into three 🎁🎁🎁.

Support OMF’s #MECFS & #LongCOVID research today and bring hope to millions. 🔗 www.omf.ngo?form=donate-....
November 10, 2025 at 4:25 PM
openmedf.bsky.social
OMF's CRC at Montreal published a review paper on ME/CFS #genetics and #epigenetics. It provides an overview of the role of DNA in how likely someone is to develop ME/CFS (susceptibility) and in how #MECFS affects the body's function (pathophysiology).

📖 Read now: ow.ly/HjW650XpmeW
An image shows Dr. Moreau and another scientist in a laboratory. Dr. Moreau is wearing glasses and a blue blazer, is pointing at a scientific poster and smiling.
November 10, 2025 at 2:20 PM
openmedf.bsky.social
Before #MECFS, Nicky was always on the move — raising her children, volunteering, and giving back. She and her husband even opened their home to more than 20 foster children, creating a safe and loving space for each one.

Read Nicky's story👉 ow.ly/szlG50XoneM.
Two black-and-white photos of Nicky. On the left, before ME/CFS, she’s in Paris, wearing a light coat and sipping coffee at a café. On the right, after ME/CFS, she’s lying in bed with glasses on, gently holding a black cat. The text beside her reads about the challenges of living with ME/CFS.
November 7, 2025 at 2:35 PM
openmedf.bsky.social
🌍 People worldwide used their limited energy to finish “ME/CFS is…” Their voices show the challenges, losses & urgent need for change. Thanks to matching donors, every gift to OMF is tripled up to $500K!

👉 Donate: www.omf.ngo?form=donate-....

#mecfs #pwME #mecfsresearch
November 6, 2025 at 4:23 PM
openmedf.bsky.social
In #MECFS, there’s evidence that microglia are activated more often than in healthy people, which contributes to #neuroinflammation. OMF’s CRC at Uppsala is analyzing microglia activity via MRI as a way of detecting neuroinflammation.

👉 Learn more: www.omf.ngo/microglia/
3D rendered image of neuron cell network on black background. Microglial cells are visible. The text reads: Science Wednesdays-Microglia.
November 5, 2025 at 4:38 PM
openmedf.bsky.social
📊OMF's Computational Research Center & patient-researcher Martha Eckey analyzed 150+ treatments reported by 3,900+ people with #MECFS & #LongCOVID through the TREATME survey.

Hear Dr. Xiao & Dr. Meadows discuss what these findings mean: ow.ly/PVvn50XmvW4.
Wenzhong Xiao with short dark hair stands against a blue gradient background, wearing a gray button-up shirt and resting his hands on a desk or podium. Text above him reads “TREATME SURVEY” in bold navy and white letters. In the lower-left corner, the text reads “#TRIPLEGIVINGNOVEMBER.
November 4, 2025 at 4:15 PM
openmedf.bsky.social
🌟 Kick off a TRIPLE MATCH Fundraiser for OMF! 🌟

Follow this link to launch in as little as 60 seconds: www.omf.ngo/digital-fundraising-toolkit/. ALL donations to your fundraiser will be tripled between November 1 -December 2, 2025!

#MECFS #LongCOVID #pwME #pwLC
Image of a person using a smartphone, with an illustrated donation icon showing a coin and heart above their hands. Text reads: ‘#Triple Giving November OMF. All donations tripled from Nov 1–Dec 2, 2025! Kick off a triple match fundraiser for OMF!
November 3, 2025 at 3:53 PM
openmedf.bsky.social
🌟Triple Giving November is back! From November 1 to December 2, all gifts to OMF will be tripled, up to $500,000, thanks to generous matching donors.

👉 Triple your gift today and learn about other ways to support OMF: ow.ly/6RrM50XlkLk.

#pwME #MECFS #pwLC #LongCOVID
A bright, warm-toned photo of a smiling woman standing outdoors in sunlight. She is wearing a white tank top and a colorful headband. On the left side of the image, there is a text box: #TRIPLE GIVING NOVEMBER OMFAU Imagine life when there is a CURE Now, imagine it 3x faster Donate now for a 3x match
November 1, 2025 at 2:19 PM
openmedf.bsky.social
💙 Triple Giving November (TGN) is returning!

From Nov 1–Dec 2, every dollar you give to OMF will be TRIPLED (up to $500,000) to advance #MECFS & #LongCOVID research. Learn what to expect during TGN here: ow.ly/oJb550XkvOB.
Group photo of OMF’s Directors in a lab with text listing #TripleGivingNovember events:Nov 11: Ron Davis, PhD and David Systrom, MD, Nov 18: Jonas Bergquist, MD, PhD and Alain Moreau, PhD, Nov 25: Chris Armstrong, PhD and Wenzhong Xiao, PhD, Dec 2: Panel discussion with all of OMF’s Directors
October 30, 2025 at 5:38 PM
openmedf.bsky.social
Oxygen uptake efficiency slope (OUES) is an indicator of cardiorespiratory health. In #MECFS, OUES has been found to be decreased, which means that some people with ME/CFS consume oxygen less efficiently.

👉 Learn more: www.omf.ngo/oxygen-uptak...
The image shows Danielle Meadows and David Systrom standing in a clinical setting. Both are smiling and facing the camera. Text on the image reads: “SCIENCE WEDNESDAYS – Oxygen Uptake Efficiency”
October 29, 2025 at 1:18 PM
openmedf.bsky.social
Whitney Dafoe: My life is a math equation. I live every moment by this: X energy use = Y outcome. I evaluate every single tiny thing I do based on this equation, often with long, in depth analysis. Imagine being healthy, not having this equation, and just acting on every impulse without thought.
The image shows Whitney with a beard and shaved hair, lying in bed. He has a serious, contemplative expression and is looking slightly to the side. His right hand is raised with three fingers extended. In the background, there is a large brown pillow and some medical equipment.
October 28, 2025 at 8:53 PM
openmedf.bsky.social
2nd International Conference on Clinical and Scientific Advances in ME/CFS and Long COVID

📍 Porto, Portugal or online

OMF speakers will include: Linda Tannenbaum, OMF Founder & CEO, David Systrom, MD, Johanna Squires. 👉 Explore the program: ow.ly/hWwK50XivaM.
Poster: 2nd International Conference on ME/CFS and Long COVID, Porto, Nov 12–13, 2025. In-person or free online; enrollment open. Poster: 2025 keynote speakers for ME/CFS & Long COVID conference; four portraits with names, topics, and affiliations: Dr. Nuno Sepúlveda, Dr. Chris Ponting, Dr. David Putrino, and Linda Tannenbaum, Founder of Open Medicine Foundation.
October 27, 2025 at 4:55 PM
openmedf.bsky.social
On Tuesday, OMF brought together Directors from all our Collaborative Research Centers for a monthly meeting to exchange insights and advance research on #MECFS and #LongCOVID. Pictured: CRC Directors, Linda Tannenbaum, Danielle Meadows, and Maureen Hanson.
This image shows a Zoom meeting with eight participants from the Open Medicine Foundation’s Collaborative Research Centers (CRCs): Alain Moreau, Jonas Bergquist, Wenzhong Xiao, Chris Armstrong, Danielle Meadows, Ronald Davis, Maureen Hanson, David Systrom, Linda Tannenbaum.
October 23, 2025 at 2:05 PM
openmedf.bsky.social
🎥 Recordings Available: Community Symposium on the Molecular Basis of ME/CFS

👉 Access them here: ow.ly/Aw2G50XcIIO

#MECFS #pwME
Picture of Ron Davis with white hair, a beard, and glasses is wearing a green checkered shirt. He is looking slightly toward the camera. Behind him, the background is softly blurred with a wall and some indistinct writing visible. At the top of the image, white text reads: “Community Symposium on the Molecular Basis of ME/CFS.”
October 21, 2025 at 9:55 PM
openmedf.bsky.social
🧬Science Wednesdays

A signaling pathway is a series of events on and within a cell that conveys information and leads to a specific function or response.

Learn more about signaling pathways and a study investigating the tetrahydrobiopterin (BH4) pathway: ow.ly/2i6A50XbPsq

#pwME #pwLC #BH4
Signaling pathway - Open Medicine Foundation
Learn about signaling pathways and why studying pathways abnormalities is important in ME/CFS research.
ow.ly
October 15, 2025 at 2:58 PM
openmedf.bsky.social
From the OMF-Supported Medical Education Resource Center (MERC) at Bateman Horne Center:

Orthostatic intolerance & #POTS are common in #MECFS & #LongCOVID. Learn signs + management tips: ow.ly/iz3b50Xb2QJ

#POTSAwarenessMonth #UnitedForME @batemanhornecenter.bsky.social
A person wearing an orange shirt is standing indoors, leaning slightly against a wall, and covering their eyes with one hand as if feeling dizzy. Below the image, text reads: “Living with Orthostatic Intolerance (OI)” followed by a quote: “If everyday tasks like standing in line or taking a shower leave you dizzy, exhausted, or foggy, you’re not alone.” — Melanie Hoppers, MD.
October 14, 2025 at 4:18 PM
openmedf.bsky.social
OMF’s Collaborative Center at Montreal, in collaboration with our Melbourne ME/CFS Collaboration, has released a new paper: Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in Myalgic Encephalomyelitis.

🔗 ow.ly/uY8x50WW32a

#mecfs #pwME
Photo of Dr. Alain Moreau and text that reads: Circulating Levels of SMPDL3B Define Metabolic Endophenotypes and Subclinical Kidney Alterations in ME, What is this research about? This study looked at a protein called SMPDL3B, which normally helps protect kidney cells. The team found that people with ME/CFS have unusual levels of this protein in their blood and urine. The study also found differences between men and women, with women showing more pronounced changes. Picture of a light bulb and text that reads: Why does it matter for people with ME/CFS?ME/CFS is a complex illness with no clear diagnostic test and cure. These findings suggest that SMPDL3B could become a new biomarker—a measurable sign of the disease. This is important because:It could help detect early organ stress that standard tests miss, It may explain some symptoms like fatigue and pain, which could be linked to kidney and metabolic dysfunction, It highlights biological differences between men and women, which could lead to more personalized care. Picture of Dr. Moreau and his team in a lab and text that reads: What is the potential impact? If confirmed in larger studies, this discovery could:Lead to a simple blood or urine test to help diagnose ME/CFS or monitor its progression,Open the door to targeted treatments that protect kidney function and restore metabolic balance, Improve precision medicine approaches, tailoring care based on biological markers and sex differences.
October 10, 2025 at 2:45 PM
openmedf.bsky.social
October 9 is DAF Day—a national day dedicated to the power of Donor-Advised Funds (DAFs) to make a difference.

This year, you can multiply your impact by directing a grant from your DAF to OMF. To learn more about DAFs, visit our ways to donate page: www.omf.ngo/ways-to-dona....
Graphic reading “October 9 is DAF Day!” with icons showing a piggy bank, a rising chart, and a hand holding a heart labeled “Donors Contribute,” “Assets Grow,” and “Charities Benefit.”
October 9, 2025 at 2:04 PM
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🧬Science Wednesdays: Metabolism

There are a couple important ways metabolism is studied in ME/CFS. For one, the #mitochondria play a central role in metabolism and there’s a growing body of evidence showing mitochondrial dysfunction in #MECFS. (1/3)
Person wearing a white shirt is writing the word ‘metabolism’ in black on a transparent surface. Their hand and cheek are visible behind the surface.
October 8, 2025 at 2:26 PM
openmedf.bsky.social
Give your car new purpose this Cartober!

When you donate your car, truck, motorcycle, RV, or boat to OMF, the proceeds from your sale will support #MECFS and #LongCOVID research.

To learn more, visit: ow.ly/4zvh50X74vv.
A person in a pink shirt holds a small yellow toy car in both hands. The background is softly blurred in shades of pink and purple. Text on the left side reads: “Every car can drive change. Support our mission with your car donation!”
October 6, 2025 at 2:41 PM
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🔬Help advance #MECFS and #LongCOVID research by joining OMF’s StudyME, a free participant registry that connects you with researchers conducting studies in these areas. Healthy volunteers needed too!

👉 www.omf.ngo/studyme/

Already part of StudyME? Please share this post to reach more people.
The image shows a young woman in a laboratory setting. She is wearing a white lab coat over a pink shirt. In the top right corner, there is the StudyME logo, which features a globe-like design made of interconnected circles in shades of teal and navy, alongside the text "StudyME."
October 2, 2025 at 3:48 PM
openmedf.bsky.social
In clinical trials, there are different treatment groups that a participant gets put into when they start the trial. Blinding is when different people involved in the trial are kept unaware, or blind, to which group the participant is in.

Learn more: www.omf.ngo/what-is-blin....
An image with a close-up of white capsules spilling out of a white pill bottle onto a dark surface. In the center, a light blue square with blue tape at the top displays the text: “Science Wednesdays: What is Blinding?”
October 1, 2025 at 2:16 PM
Reposted by Open Medicine Foundation (OMF)
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#MEAction is asking you to take action to save telehealth NOW!

You can call or email your member of Congress. To make this action easier, we have drafted up a sample script you can use: www.meactions.org/telehealth

#Telehealth #PwME #LongCovid #MECFS #Congress #Disability
Image of a megaphone at bottom corner and Capitol building in top right corner. Text: Contact congress today to keep telehealth!
September 30, 2025 at 2:30 AM
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🛍️ Shop with iGive! With iGive you can shop online at 1,700+ stores, and a percentage of your purchase will go directly to OMF, all at no cost to you or OMF.

Shop & Support OMF 👉 ow.ly/23iX50X3AV7.

#ShopWithPurpose #pwME #pwLC
Graphic with the title “Shop with Purpose!” showing a phone with a shopping cart image and OMF logo. Steps on the right: Visit iGive (bit.ly/iGiveOMF), Sign up for a free account, Shop online — a percentage goes to OMF.
September 29, 2025 at 1:26 PM