Naina Gour
@nainagour.bsky.social
Assistant Professor @ Johns Hopkins researching regulatory neutrophils. Yes, they regulate things now. We’re all adjusting. 😄
Pinned
New paper alert! We show essential role of #fibroblasts derived #complement C3 in maintaining #Il33-#ILC2 hub during airway #allergy. Congratulations to hard working Ph.D. Students @atakkatan.bsky.social @aishwaryamagesh.bsky.social www.cell.com/cell-reports... @johnshopkinsmmi.bsky.social
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs)
that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived
IL-13 supports AF function...
www.cell.com
Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement
Reposted by Naina Gour
An orally active positive allosteric modulator of the human Mas-related G protein–coupled receptor X1 is a potential therapy for neuropathic pain @jhu.edu
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
December 17, 2025 at 9:52 PM
An orally active positive allosteric modulator of the human Mas-related G protein–coupled receptor X1 is a potential therapy for neuropathic pain @jhu.edu
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Naina Gour
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs) that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived IL-13 supports AF function, thus engaging in a pro-allergic dialogue that promotes type 2 immunity.
dlvr.it
December 13, 2025 at 3:38 PM
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
Reposted by Naina Gour
Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
December 9, 2025 at 4:10 PM
Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes @cp-iscience.bsky.social
www.cell.com/iscience/ful...
www.cell.com/iscience/ful...
Reposted by Naina Gour
The fun leaving your body the moment you're done with the science and it's time to get it published
December 4, 2025 at 11:15 AM
The fun leaving your body the moment you're done with the science and it's time to get it published
Reposted by Naina Gour
Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement
New paper alert! We show essential role of #fibroblasts derived #complement C3 in maintaining #Il33-#ILC2 hub during airway #allergy. Congratulations to hard working Ph.D. Students @atakkatan.bsky.social @aishwaryamagesh.bsky.social www.cell.com/cell-reports... @johnshopkinsmmi.bsky.social
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy
Atakkatan et al. identify a distinct subset of C3+IL-33+ adventitial fibroblasts (AFs)
that drives allergic inflammation by maintaining ILC2 responses. In turn, ILC2-derived
IL-13 supports AF function...
www.cell.com
December 3, 2025 at 1:34 AM
Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement
Reposted by Naina Gour
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy @cp-cellreports.bsky.social @atakkatan.bsky.social @hopkinsmedicine.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
December 1, 2025 at 7:52 PM
Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy @cp-cellreports.bsky.social @atakkatan.bsky.social @hopkinsmedicine.bsky.social
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Naina Gour
How a mattress sensor and smartwatch confirmation led to a patient's diagnosis of complete heart block and need for a pacemaker @nejm.org www.nejm.org/doi/full/10....
November 29, 2025 at 4:02 PM
How a mattress sensor and smartwatch confirmation led to a patient's diagnosis of complete heart block and need for a pacemaker @nejm.org www.nejm.org/doi/full/10....
Reposted by Naina Gour
Thrilled to share that neutrophils produce extra long fibrillar components named proteoglycofili or PGF. PGF are released by living neutrophils and do not contain DNA. They might look like NETs but are not NETs…
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Proteoglycofili are glycosaminoglycan-containing fibrillar components released by neutrophils to neutralize bacteria
Alternative to the formation of NETs, André et al. describe here that viable neutrophils
may release a fibrillar component named proteoglycofili or PGF upon stimulation. PGF
formation is associated wi...
www.cell.com
November 27, 2025 at 9:01 PM
Thrilled to share that neutrophils produce extra long fibrillar components named proteoglycofili or PGF. PGF are released by living neutrophils and do not contain DNA. They might look like NETs but are not NETs…
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Reposted by Naina Gour
GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F high neutrophils in allergic airway inflammation in mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 27, 2025 at 3:09 AM
GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F high neutrophils in allergic airway inflammation in mice @natcomms.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Naina Gour
New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org
A bacterial toxin disarms gut defenses against inflammation
Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice
science.org
November 20, 2025 at 7:25 PM
New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org