Markos Tsitsianopoulos
@mtsitsian.bsky.social
IMPRS-GS PhD Student at Papantonis Lab, University Medical Center Göttingen | BSc. Biochemistry and Biotechnology, UTH | MSc. Stem Cells and Regenerative Medicine, AUTH
Reposted by Markos Tsitsianopoulos
Hello! We are #NewHere. The KFO 5002 is a clinical research group at the University Medical Center Göttingen and funded by the DFG. Our research focuses on 'Deciphering Genome Dynamics for Subtype-specific Therapy in #PancreaticCancer'. Currently in our second funding period!
January 29, 2025 at 7:58 AM
Hello! We are #NewHere. The KFO 5002 is a clinical research group at the University Medical Center Göttingen and funded by the DFG. Our research focuses on 'Deciphering Genome Dynamics for Subtype-specific Therapy in #PancreaticCancer'. Currently in our second funding period!
Reposted by Markos Tsitsianopoulos
Last day of the @spp2202.bsky.social Closing Retreat in Goettingen ending in a high note with Stavros Lomvardas discussing the peculiar 3D attributes of the OR chromatin landscape!
November 12, 2025 at 10:23 AM
Last day of the @spp2202.bsky.social Closing Retreat in Goettingen ending in a high note with Stavros Lomvardas discussing the peculiar 3D attributes of the OR chromatin landscape!
Reposted by Markos Tsitsianopoulos
@karsten-rippe.bsky.social rocking down memory lane and along single cell genomics data in Day 2 of the @spp2202.bsky.social Closing Retreat in Goettingen!
November 11, 2025 at 2:09 PM
@karsten-rippe.bsky.social rocking down memory lane and along single cell genomics data in Day 2 of the @spp2202.bsky.social Closing Retreat in Goettingen!
Reposted by Markos Tsitsianopoulos
The Closing Scientific Retreat of @spp2202.bsky.social is under way in Goettingen with Gerd Blobel delivering the first Keynote lecture on LDB11-mediated looping of chromatin.
November 10, 2025 at 2:51 PM
The Closing Scientific Retreat of @spp2202.bsky.social is under way in Goettingen with Gerd Blobel delivering the first Keynote lecture on LDB11-mediated looping of chromatin.
Great piece of work!
Happy to share our latest publication, in which we show that the arrangement of nucleosomes around CTCF sites contributes to higher-order organisation of chromatin into TADs: www.embopress.org/doi/full/10....
October 27, 2025 at 4:16 PM
Great piece of work!
Reposted by Markos Tsitsianopoulos
Paper accepted!!!!
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
September 23, 2025 at 10:04 PM
Paper accepted!!!!
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
Congratultions to @lizebonaaugust.bsky.social Blanca del Rosal and Leslie Yeo it was a pleasure to work together on this amazing project! 🎊🎊🎊🎊
Reposted by Markos Tsitsianopoulos
In our latest preprinted work, Yajie and Kostas combine computational analysis with precision KO of single variant U1 snRNA genes in human iPSCs to find pronounced deregulation of both gene expression and splicing that seem to affect the cell cycle and the differentiation potency of stem cells. 1/n
September 16, 2025 at 8:33 AM
In our latest preprinted work, Yajie and Kostas combine computational analysis with precision KO of single variant U1 snRNA genes in human iPSCs to find pronounced deregulation of both gene expression and splicing that seem to affect the cell cycle and the differentiation potency of stem cells. 1/n
Reposted by Markos Tsitsianopoulos
FYI: New online! RNA polymerase II transcription compartments — from factories to condensates
RNA polymerase II transcription compartments — from factories to condensates
Nature Reviews Genetics, Published online: 19 June 2025; doi:10.1038/s41576-025-00859-6In this Review, Rippe and Papantonis describe advances in understanding the role of transcription compartments in gene regulation, specifically by collating and contrasting historical work on transcription factories with more recent work on transcriptional condensates.
www.nature.com
July 10, 2025 at 3:02 PM
FYI: New online! RNA polymerase II transcription compartments — from factories to condensates
Reposted by Markos Tsitsianopoulos
How to represent genomes in 3D?
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
June 27, 2025 at 8:13 AM
How to represent genomes in 3D?
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
Reposted by Markos Tsitsianopoulos
This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u
A short thread follows 1/n
A short thread follows 1/n
June 19, 2025 at 4:37 PM
This is a piece that I and @karsten-rippe.bsky.social discussing a lot, and a topic that is very close to my heart. The editors @naturerevgenet.bsky.social gave us the stage to do so, and the final version of our review is now available under this link: rdcu.be/erP1u
A short thread follows 1/n
A short thread follows 1/n
Reposted by Markos Tsitsianopoulos
Starting science at our retreat 2025 at Harnack Haus with the first talk by our guest @keyfm.bsky.social on evolutionary genomics of microbial pathogens. Interesting topic distracting from knowing the nice weather and surrounding.
June 18, 2025 at 2:06 PM
Starting science at our retreat 2025 at Harnack Haus with the first talk by our guest @keyfm.bsky.social on evolutionary genomics of microbial pathogens. Interesting topic distracting from knowing the nice weather and surrounding.