Pinned
Mr Misael
@mrmisael.bsky.social
· Nov 13
Pre-print: Early influenza virus characterisation and vaccine effectiveness in England in autumn 2025
New data on early influenza virus characterisation and vaccine effectiveness in England in autumn 2025, a period dominated by influenza A(H3N2) subclade K.
www.gov.uk
UKHSA just published a pre-print on preliminary VE of H3N2 vaccination vs subclade K - results give some peace of mind: VE vs hospitalization ranges from 30-40% for adults, about 70-75% for children
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
Pre-print on the latest human case of H5Nx from Mexico ( and first-ever H5N2 ) around Sept 2025
Young, female, save for her BMI no major risk factor identified; survived but hemoptysis and lung damage observed. Not to be confused with the fatal H5N1 Mx case.
www.medrxiv.org/content/10.1...
Young, female, save for her BMI no major risk factor identified; survived but hemoptysis and lung damage observed. Not to be confused with the fatal H5N1 Mx case.
www.medrxiv.org/content/10.1...
Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult
Background Infection of backyard and poultry with low pathogenicity avian influenza LPAI A(H5N2) viruses has occurred in Mexico since 1994, and the first human infection caused by this influenza virus...
www.medrxiv.org
November 28, 2025 at 2:50 AM
Pre-print on the latest human case of H5Nx from Mexico ( and first-ever H5N2 ) around Sept 2025
Young, female, save for her BMI no major risk factor identified; survived but hemoptysis and lung damage observed. Not to be confused with the fatal H5N1 Mx case.
www.medrxiv.org/content/10.1...
Young, female, save for her BMI no major risk factor identified; survived but hemoptysis and lung damage observed. Not to be confused with the fatal H5N1 Mx case.
www.medrxiv.org/content/10.1...
Reposted by Mr Misael
NEW: Egg producers suspect bird flu is traveling through the air. The USDA didn’t test the theory after a disastrous Midwestern outbreak.
Here’s how we did.
By @natlash.bsky.social
Here’s how we did.
By @natlash.bsky.social
How ProPublica Investigated a Bird Flu Outbreak in America’s Heartland
Early this year, bird flu ripped through 80 farms in Ohio and Indiana. Using genetic markers, wind simulations, satellite imagery, property records and more, we found that the virus could’ve been airb...
www.propublica.org
November 18, 2025 at 2:00 PM
NEW: Egg producers suspect bird flu is traveling through the air. The USDA didn’t test the theory after a disastrous Midwestern outbreak.
Here’s how we did.
By @natlash.bsky.social
Here’s how we did.
By @natlash.bsky.social
Reposted by Mr Misael
Mike Coston on the latest Cambodian H5N1 fatality, and its context: afludiary.blogspot.com/2025/11/camb...
Cambodian MOH Announces 18th H5N1 Case of 2025
#18,948 Three years ago an older clade of H5N1 (2.3.2.1.x) reemerged in Cambodia's population after a 9 year absence, spilling over into 6 ...
afludiary.blogspot.com
November 16, 2025 at 4:04 PM
Mike Coston on the latest Cambodian H5N1 fatality, and its context: afludiary.blogspot.com/2025/11/camb...
Reposted by Mr Misael
CDC FluView is back, and our fears look like reality.
50.8% of circulating H3N2 viruses belong to the 2a.3a.1-K subclade, which have 2 mutations in a very important antigenic site. Our own 2025-2026 vaccine immunogenicity data will be posted in the next couple of weeks.
www.cdc.gov/fluview/surv...
50.8% of circulating H3N2 viruses belong to the 2a.3a.1-K subclade, which have 2 mutations in a very important antigenic site. Our own 2025-2026 vaccine immunogenicity data will be posted in the next couple of weeks.
www.cdc.gov/fluview/surv...
Weekly US Influenza Surveillance Report: Key Updates for Week 45, ending November 8, 2025
Seasonal influenza activity is low.
www.cdc.gov
November 14, 2025 at 8:33 PM
CDC FluView is back, and our fears look like reality.
50.8% of circulating H3N2 viruses belong to the 2a.3a.1-K subclade, which have 2 mutations in a very important antigenic site. Our own 2025-2026 vaccine immunogenicity data will be posted in the next couple of weeks.
www.cdc.gov/fluview/surv...
50.8% of circulating H3N2 viruses belong to the 2a.3a.1-K subclade, which have 2 mutations in a very important antigenic site. Our own 2025-2026 vaccine immunogenicity data will be posted in the next couple of weeks.
www.cdc.gov/fluview/surv...
Reposted by Mr Misael
The deadly fever in Ethiopia has been identified as Marburg disease.
It’s the first time a Marburg outbreak has been identified in Ethiopia.
#IDsky 🧪
www.afro.who.int/countries/et...
It’s the first time a Marburg outbreak has been identified in Ethiopia.
#IDsky 🧪
www.afro.who.int/countries/et...
Ethiopia confirms first outbreak of Marburg virus disease
Ethiopia’s Ministry of Health has confirmed an outbreak of Marburg virus disease in the South Ethiopia Region, the first of its kind in the country, following laboratory testing of samples from a clus...
www.afro.who.int
November 14, 2025 at 8:07 PM
The deadly fever in Ethiopia has been identified as Marburg disease.
It’s the first time a Marburg outbreak has been identified in Ethiopia.
#IDsky 🧪
www.afro.who.int/countries/et...
It’s the first time a Marburg outbreak has been identified in Ethiopia.
#IDsky 🧪
www.afro.who.int/countries/et...
UKHSA just published a pre-print on preliminary VE of H3N2 vaccination vs subclade K - results give some peace of mind: VE vs hospitalization ranges from 30-40% for adults, about 70-75% for children
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
Pre-print: Early influenza virus characterisation and vaccine effectiveness in England in autumn 2025
New data on early influenza virus characterisation and vaccine effectiveness in England in autumn 2025, a period dominated by influenza A(H3N2) subclade K.
www.gov.uk
November 13, 2025 at 1:17 AM
UKHSA just published a pre-print on preliminary VE of H3N2 vaccination vs subclade K - results give some peace of mind: VE vs hospitalization ranges from 30-40% for adults, about 70-75% for children
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
#testnegativedesign
@freja-kirsebom.bsky.social
www.gov.uk/government/p...
Reposted by Mr Misael
Expanded version of the last graph, both in the number of years & in its horizontal stretching.
#AusFlu2025 peaked in July, but has declined slowly, meaning there's been *lots* of #flu around for a long time.
Sept-2025 was the 2nd biggest Sept since 2017, and Oct-2025 was the biggest Oct on record
#AusFlu2025 peaked in July, but has declined slowly, meaning there's been *lots* of #flu around for a long time.
Sept-2025 was the 2nd biggest Sept since 2017, and Oct-2025 was the biggest Oct on record
November 8, 2025 at 4:41 AM
Expanded version of the last graph, both in the number of years & in its horizontal stretching.
#AusFlu2025 peaked in July, but has declined slowly, meaning there's been *lots* of #flu around for a long time.
Sept-2025 was the 2nd biggest Sept since 2017, and Oct-2025 was the biggest Oct on record
#AusFlu2025 peaked in July, but has declined slowly, meaning there's been *lots* of #flu around for a long time.
Sept-2025 was the 2nd biggest Sept since 2017, and Oct-2025 was the biggest Oct on record
Reposted by Mr Misael
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5
November 7, 2025 at 2:41 PM
I want to spell this out in case the implications aren't clear:
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited.
The file allowed this. Cut that - cut off all tools the public & others were using.
Arizona resident dies of Yersinia pestis (aka "plague) - pneumonic presentation - Coconino county www.bbc.com/news/article...
@crof.bsky.social @crofkilian.bsky.social
@crof.bsky.social @crofkilian.bsky.social
Arizona resident dies from pneumonic plague, health officials say
This was the first recorded death from the disease in Coconino County since 2007.
www.bbc.com
July 13, 2025 at 4:15 AM
Arizona resident dies of Yersinia pestis (aka "plague) - pneumonic presentation - Coconino county www.bbc.com/news/article...
@crof.bsky.social @crofkilian.bsky.social
@crof.bsky.social @crofkilian.bsky.social
Mexico reaches 3,001 measles cases and 9 deaths
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
July 2, 2025 at 9:45 PM
Mexico reaches 3,001 measles cases and 9 deaths
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
Mexico outbreak: 5 deaths due to #measles and 53 due to whooping cough (pertussis)
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
June 2, 2025 at 8:59 PM
Mexico outbreak: 5 deaths due to #measles and 53 due to whooping cough (pertussis)
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
@crof.bsky.social
Source: Federal Ministry of Health
www.gob.mx/cms/uploads/...
Mexico Ministry of Health (Federal level) just confirmed the death toll in the measles outbreak now stands at 4
@crof.bsky.social @borisosman.bsky.social
Source:
www.gob.mx/cms/uploads/...
@crof.bsky.social @borisosman.bsky.social
Source:
www.gob.mx/cms/uploads/...
May 20, 2025 at 7:40 PM
Mexico Ministry of Health (Federal level) just confirmed the death toll in the measles outbreak now stands at 4
@crof.bsky.social @borisosman.bsky.social
Source:
www.gob.mx/cms/uploads/...
@crof.bsky.social @borisosman.bsky.social
Source:
www.gob.mx/cms/uploads/...
Goverment of Sonora confirms the death of a 1 year old due to #measles
The girl is from Chihuahua w/ temporary residence in Sonora. Due to the gender n age it seems to be a distint case from the 2 deceased kids confirmed by Chihuahua
@crof.bsky.social
Source
sonora.gob.mx/gobierno/acc...
The girl is from Chihuahua w/ temporary residence in Sonora. Due to the gender n age it seems to be a distint case from the 2 deceased kids confirmed by Chihuahua
@crof.bsky.social
Source
sonora.gob.mx/gobierno/acc...
May 20, 2025 at 7:20 PM
Goverment of Sonora confirms the death of a 1 year old due to #measles
The girl is from Chihuahua w/ temporary residence in Sonora. Due to the gender n age it seems to be a distint case from the 2 deceased kids confirmed by Chihuahua
@crof.bsky.social
Source
sonora.gob.mx/gobierno/acc...
The girl is from Chihuahua w/ temporary residence in Sonora. Due to the gender n age it seems to be a distint case from the 2 deceased kids confirmed by Chihuahua
@crof.bsky.social
Source
sonora.gob.mx/gobierno/acc...
2 more deaths due to #measles in Mexico
Ministry of Health of Chihuahua confirms a 7 yo and an 11 month old baby passed away due to measles in the Ojinaga and Namiquipa counties
The toll now stands at 3
@crof.bsky.social
Source: press release of Chihuahua Gov
chihuahua.gob.mx/index.php/pr...
Ministry of Health of Chihuahua confirms a 7 yo and an 11 month old baby passed away due to measles in the Ojinaga and Namiquipa counties
The toll now stands at 3
@crof.bsky.social
Source: press release of Chihuahua Gov
chihuahua.gob.mx/index.php/pr...
Reporta Secretaría de Salud el fallecimiento de dos menores de edad por sarampión | Portal Gubernamental del Estado de Chihuahua
La Secretaría de Salud reportó el fallecimiento de dos menores de edad, uno de 7 años y otro de 11 meses de nacido, a causa de complicaciones derivadas del sarampión. Ambos presentaron neumonía, sumad...
chihuahua.gob.mx
May 20, 2025 at 2:20 AM
2 more deaths due to #measles in Mexico
Ministry of Health of Chihuahua confirms a 7 yo and an 11 month old baby passed away due to measles in the Ojinaga and Namiquipa counties
The toll now stands at 3
@crof.bsky.social
Source: press release of Chihuahua Gov
chihuahua.gob.mx/index.php/pr...
Ministry of Health of Chihuahua confirms a 7 yo and an 11 month old baby passed away due to measles in the Ojinaga and Namiquipa counties
The toll now stands at 3
@crof.bsky.social
Source: press release of Chihuahua Gov
chihuahua.gob.mx/index.php/pr...
FYI @crof.bsky.social Measles update Mexico, 2 deaths
2 confirmed deaths in Mexico´s #measles outbreak, both males & unvaccinated
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
May 17, 2025 at 4:58 AM
FYI @crof.bsky.social Measles update Mexico, 2 deaths
2 confirmed deaths in Mexico´s #measles outbreak, both males & unvaccinated
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
May 16, 2025 at 4:24 AM
2 confirmed deaths in Mexico´s #measles outbreak, both males & unvaccinated
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
31 yo, resident of Ascensión County, Chihuahua. Dx April 7
7 yo, Ojinaga County, Chihuahua, Dx April 16
Source: Base EFE of the Mexican (Federal) MoH
gob.mx/salud/docume...
@Crof
H/T @borisosman.bsky.social
Chihuahua, Mexico reaches 713 measles confirmed cases surpassing its neighbour across the border, Texas
#Measles
@crof.bsky.social
Source. Official update by Gov of State of Chihuahua:
rad.ssch.gob.mx/rad/nocache/...
#Measles
@crof.bsky.social
Source. Official update by Gov of State of Chihuahua:
rad.ssch.gob.mx/rad/nocache/...
rad.ssch.gob.mx
April 27, 2025 at 6:46 PM
Chihuahua, Mexico reaches 713 measles confirmed cases surpassing its neighbour across the border, Texas
#Measles
@crof.bsky.social
Source. Official update by Gov of State of Chihuahua:
rad.ssch.gob.mx/rad/nocache/...
#Measles
@crof.bsky.social
Source. Official update by Gov of State of Chihuahua:
rad.ssch.gob.mx/rad/nocache/...
362 confirmed #measles cases in Mexico - 7 states affected
Source: Mx Minister of Health press conference before the Mexican President - around 16:10
www.youtube.com/watch?v=Mc4e...
@crof.bsky.social
Source: Mx Minister of Health press conference before the Mexican President - around 16:10
www.youtube.com/watch?v=Mc4e...
@crof.bsky.social
April 15, 2025 at 9:01 PM
362 confirmed #measles cases in Mexico - 7 states affected
Source: Mx Minister of Health press conference before the Mexican President - around 16:10
www.youtube.com/watch?v=Mc4e...
@crof.bsky.social
Source: Mx Minister of Health press conference before the Mexican President - around 16:10
www.youtube.com/watch?v=Mc4e...
@crof.bsky.social
1st measles death in Chihuahua, Mexico, 31 y.o. male, unvaccinated
#Sarampión #Measles
@crof.bsky.social
Source:
elfinanciero.com.mx/estados/2025...
#Sarampión #Measles
@crof.bsky.social
Source:
elfinanciero.com.mx/estados/2025...
Confirman primera muerte por brote de sarampión en México: Un hombre de 31 años que no tenía vacuna
Chihuahua registró la primera muerte por el brote de sarampión en México; los contagios en la entidad se han disparado con 261 casos confirmados.
elfinanciero.com.mx
April 12, 2025 at 7:29 AM
1st measles death in Chihuahua, Mexico, 31 y.o. male, unvaccinated
#Sarampión #Measles
@crof.bsky.social
Source:
elfinanciero.com.mx/estados/2025...
#Sarampión #Measles
@crof.bsky.social
Source:
elfinanciero.com.mx/estados/2025...
Human case H5N1 confirmed in Mexico, "in serious condition"
Girl, 3 y.o., received oselmativir, hopitalized, resident of Durango state
Source: Federal Ministry of Health, press release>
@crof.bsky.social @bnonews.com
#H5N1
www.gob.mx/salud/prensa...
Girl, 3 y.o., received oselmativir, hopitalized, resident of Durango state
Source: Federal Ministry of Health, press release>
@crof.bsky.social @bnonews.com
#H5N1
www.gob.mx/salud/prensa...
Secretaría de Salud informa la detección del primer caso humano de influenza aviar A (H5N1)
www.gob.mx
April 4, 2025 at 10:18 PM
Human case H5N1 confirmed in Mexico, "in serious condition"
Girl, 3 y.o., received oselmativir, hopitalized, resident of Durango state
Source: Federal Ministry of Health, press release>
@crof.bsky.social @bnonews.com
#H5N1
www.gob.mx/salud/prensa...
Girl, 3 y.o., received oselmativir, hopitalized, resident of Durango state
Source: Federal Ministry of Health, press release>
@crof.bsky.social @bnonews.com
#H5N1
www.gob.mx/salud/prensa...
Mexico, #Measles outbreak update:
95 confirmed measles cases in Chihuahua state
Source:
Ministry of Health of Chihuahua State
chihuahua.gob.mx/index.php/pr...
@crof.bsky.social
@jusdayda.bsky.social
@health.bnonews.com
chihuahua.gob.mx/index.php/pr...
95 confirmed measles cases in Chihuahua state
Source:
Ministry of Health of Chihuahua State
chihuahua.gob.mx/index.php/pr...
@crof.bsky.social
@jusdayda.bsky.social
@health.bnonews.com
chihuahua.gob.mx/index.php/pr...
March 29, 2025 at 12:21 AM
Mexico, #Measles outbreak update:
95 confirmed measles cases in Chihuahua state
Source:
Ministry of Health of Chihuahua State
chihuahua.gob.mx/index.php/pr...
@crof.bsky.social
@jusdayda.bsky.social
@health.bnonews.com
chihuahua.gob.mx/index.php/pr...
95 confirmed measles cases in Chihuahua state
Source:
Ministry of Health of Chihuahua State
chihuahua.gob.mx/index.php/pr...
@crof.bsky.social
@jusdayda.bsky.social
@health.bnonews.com
chihuahua.gob.mx/index.php/pr...
Seroprevalence of measles antibodies, 2012-13, México & Nicaragua. Effective coverage obv lower than crude reported coverages. Some geographical clues, perhaps electricity & cold chain disruptions, malnutration or not discussed: the use of only ELISA methods
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
Comparative Estimates of Crude and Effective Coverage of Measles Immunization in Low-Resource Settings: Findings from Salud Mesoamérica 2015
Timely and accurate measurement of population protection against measles is critical for decision-making and prevention of outbreaks. However, little is known about how survey-based estimates of immun...
pmc.ncbi.nlm.nih.gov
March 23, 2025 at 7:35 PM
Seroprevalence of measles antibodies, 2012-13, México & Nicaragua. Effective coverage obv lower than crude reported coverages. Some geographical clues, perhaps electricity & cold chain disruptions, malnutration or not discussed: the use of only ELISA methods
pmc.ncbi.nlm.nih.gov/articles/PMC...
pmc.ncbi.nlm.nih.gov/articles/PMC...
If the Chihuahua measles outbreak reaches the tarahumara community, say South of the state like Guachochi, Bocoyna, things would get really bad.
March 14, 2025 at 10:16 PM
If the Chihuahua measles outbreak reaches the tarahumara community, say South of the state like Guachochi, Bocoyna, things would get really bad.