Ali Mohebi
@mohebial.bsky.social
Loves stories. Behavioral Neurobiologist. Dopamine. Science. Technology. Reason. Photography. Baking. Films. Roger's Pink Floyd.
Assistant Professor of Psychology, UW-Madison
http://mohebi-associates.org/
Assistant Professor of Psychology, UW-Madison
http://mohebi-associates.org/
Pinned
Ali Mohebi
@mohebial.bsky.social
· May 1
There’s plenty to gripe about in academia these days, but one thing I’ll never take for granted: the chance to dive into deep conversations about cognition and neuroscience with brilliant minds every semester. Wouldn’t trade it for anything.
:: Final session for our Psych 711 class
:: Final session for our Psych 711 class
Reposted by Ali Mohebi
Delighted to see this finally out: rdcu.be/eO9oW
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
Subsecond dopamine fluctuations do not specify the vigor of ongoing actions
Nature Neuroscience - Liu and colleagues show that the vigor (that is, speed and amplitude) of dexterous movements is not controlled by ongoing fluctuations in extracellular dopamine within the...
rdcu.be
November 10, 2025 at 3:43 PM
Delighted to see this finally out: rdcu.be/eO9oW
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
We tested whether brief striatal dopamine release events influence the vigor of skilled movements. Despite popular belief, we did not find any evidence linking rapid dopamine dynamics to motor vigor on a moment-by-moment basis.
Reposted by Ali Mohebi
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
VTA dopamine neuron activity produces spatially organized value representations https://www.biorxiv.org/content/10.1101/2025.11.04.685995v1
November 7, 2025 at 8:46 PM
How do VTA DA neurons sculpt downstream representations to reinforce actions? VERY excited about our new preprint (by Alex Pan Vazquez & @czimmerman.bsky.social )
Friedman once famously wrote: "The Social Responsibility of Business Is to Increase Its Profits", which arguably changed the way most Americans started thinking about business...
So I'm asking Cornell and others, what do you think the social responsibility of universities are?
So I'm asking Cornell and others, what do you think the social responsibility of universities are?
November 7, 2025 at 9:14 PM
Friedman once famously wrote: "The Social Responsibility of Business Is to Increase Its Profits", which arguably changed the way most Americans started thinking about business...
So I'm asking Cornell and others, what do you think the social responsibility of universities are?
So I'm asking Cornell and others, what do you think the social responsibility of universities are?
What a great TV show...
November 7, 2025 at 5:44 PM
What a great TV show...
Somehow missed this one. It appears to be yet another important study from the Kaeser group: "GRAB signals aren't pure; there is always cross-talk, and sometimes the cross-talks become problematic. And no, HEK cell measurements don't immediately translate in vivo..."
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Innervation density governs crosstalk of GPCR-based norepinephrine and dopamine sensors
GPCR-based fluorescent sensors are widely used to correlate neuromodulatory signaling with brain function. While experiments in transfected cells often reveal selectivity for individual neurotransmitt...
www.biorxiv.org
November 6, 2025 at 4:49 PM
Somehow missed this one. It appears to be yet another important study from the Kaeser group: "GRAB signals aren't pure; there is always cross-talk, and sometimes the cross-talks become problematic. And no, HEK cell measurements don't immediately translate in vivo..."
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Your job is not to protect the institution. You have it backwards: it's the institution's job to protect you.
November 6, 2025 at 4:48 AM
Your job is not to protect the institution. You have it backwards: it's the institution's job to protect you.
Nice! The newest version of my favorite figure-editing/poster-making software is now free! Give it a chance, shift+delete Adobe.
www.affinity.studio
(I don't know how to feel about the Canva acquisition thing going on. My gut feeling: I don't trust it, but I will give them a chance)
www.affinity.studio
(I don't know how to feel about the Canva acquisition thing going on. My gut feeling: I don't trust it, but I will give them a chance)
October 30, 2025 at 10:59 PM
Nice! The newest version of my favorite figure-editing/poster-making software is now free! Give it a chance, shift+delete Adobe.
www.affinity.studio
(I don't know how to feel about the Canva acquisition thing going on. My gut feeling: I don't trust it, but I will give them a chance)
www.affinity.studio
(I don't know how to feel about the Canva acquisition thing going on. My gut feeling: I don't trust it, but I will give them a chance)
This is the end. Gotham is falling. Ra's al Ghul has won. Sad day for our democracy, if I may say so.
Talk about an in-flight meal.
For the first time, researchers have captured rats hunting bats by grabbing them from the sky. Learn more: https://scim.ag/3Jqldmn
For the first time, researchers have captured rats hunting bats by grabbing them from the sky. Learn more: https://scim.ag/3Jqldmn
October 27, 2025 at 11:24 PM
This is the end. Gotham is falling. Ra's al Ghul has won. Sad day for our democracy, if I may say so.
All canonical views are wrong, but some are useful.
October 27, 2025 at 1:48 PM
All canonical views are wrong, but some are useful.
Reposted by Ali Mohebi
The Cummings Lab is hiring a postdoc to work in the areas of reward and addiction! Please see the ad below:
October 23, 2025 at 6:22 PM
The Cummings Lab is hiring a postdoc to work in the areas of reward and addiction! Please see the ad below:
Nature manuscript adviser. Not too bad, I uploaded one of my previously published manuscripts and got some good feedback. I suppose it's just GPT, further trained on a corpus of manuscript peer reviews that Nature owns...
October 22, 2025 at 2:17 PM
Nature manuscript adviser. Not too bad, I uploaded one of my previously published manuscripts and got some good feedback. I suppose it's just GPT, further trained on a corpus of manuscript peer reviews that Nature owns...
Reposted by Ali Mohebi
Thanks all for the feedback. Some slight updates on this version, along with some further explanation on my neglected Medium page here: medium.com/metascientif...
October 21, 2025 at 5:52 PM
Thanks all for the feedback. Some slight updates on this version, along with some further explanation on my neglected Medium page here: medium.com/metascientif...
Powerful essay by Byung-chul Han:
From a pathological standpoint, the incipient 21 century is determined neither by bacteria nor by viruses, but by neurons...
From a pathological standpoint, the incipient 21 century is determined neither by bacteria nor by viruses, but by neurons...
October 20, 2025 at 8:55 PM
Powerful essay by Byung-chul Han:
From a pathological standpoint, the incipient 21 century is determined neither by bacteria nor by viruses, but by neurons...
From a pathological standpoint, the incipient 21 century is determined neither by bacteria nor by viruses, but by neurons...
Reposted by Ali Mohebi
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
October 16, 2025 at 3:00 PM
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
Reposted by Ali Mohebi
Nice preprint from Veronica Alvarez's group on cortically-evoked DA mediated by ACh! I We observed something quite similar in birds, and interesting to see the sensory/prefrontal distinction
Cholinergic-dependent dopamine signals in mouse dorsal striatum are regulated by frontal but not sensory cortices
Everyday decisions depend on linking sensory stimuli with actions and outcomes. The striatum supports these sensorimotor associations through dopamine-dependent plasticity. Thus, the timing and magnit...
www.biorxiv.org
October 14, 2025 at 7:29 PM
Nice preprint from Veronica Alvarez's group on cortically-evoked DA mediated by ACh! I We observed something quite similar in birds, and interesting to see the sensory/prefrontal distinction
Goodbye ChatGPT wrappers. Hello, ChatGPT!
October 7, 2025 at 12:53 AM
Goodbye ChatGPT wrappers. Hello, ChatGPT!
Did NIH cancel all the NOSIs? I first noticed that NOT-MH-24-100, which had a prior expiration date of May 2027, now shows as expired (as of September 9, 2025). I then realized there are no active NOSIs...
. @rosalafersousa.bsky.social
. @rosalafersousa.bsky.social
October 5, 2025 at 3:50 PM
Did NIH cancel all the NOSIs? I first noticed that NOT-MH-24-100, which had a prior expiration date of May 2027, now shows as expired (as of September 9, 2025). I then realized there are no active NOSIs...
. @rosalafersousa.bsky.social
. @rosalafersousa.bsky.social
Excited to hear the latest science updates from @czimmerman.bsky.social on Monday, 1-2 pm CST. You can join us too—either on Zoom or in person! bit.ly/3VOJrcy
October 5, 2025 at 2:25 PM
Excited to hear the latest science updates from @czimmerman.bsky.social on Monday, 1-2 pm CST. You can join us too—either on Zoom or in person! bit.ly/3VOJrcy
I know the organizers, and I score them highly on the orthogonal axes of being great scientists and great human beings. They have put together a terrific one day symposium, the day before SfN in San Diego. Register if you're there early!
Going to SfN? Join us for the first Middle-Eastern Systems Neuroscience meeting the day before SfN! We’ve got great speakers, all with Middle-Eastern origins! But also an exclusive chance to network with leading Neuroscientists!
Visit our website for more information:
www.middleeastneuro.com
Visit our website for more information:
www.middleeastneuro.com
Middle Eastern Systems Neuroscience Symposium
Join the Middle Eastern Systems Neuroscience Symposium on November 14, 2025, at UCSD Faculty Club, San Diego, in conjunction with the Society for Neuroscience (SfN) meeting. This event fosters scienti...
www.middleeastneuro.com
October 2, 2025 at 3:50 PM
I know the organizers, and I score them highly on the orthogonal axes of being great scientists and great human beings. They have put together a terrific one day symposium, the day before SfN in San Diego. Register if you're there early!
Join us today at 1 pm CST for a lecture by @mariedoyle.bsky.social
Title: Alcohol abstinence precipitates increased alcohol seeking and compulsive intake in association with phenotypic BNST dynamics
bit.ly/3VOJrcy
Title: Alcohol abstinence precipitates increased alcohol seeking and compulsive intake in association with phenotypic BNST dynamics
bit.ly/3VOJrcy
September 29, 2025 at 1:50 PM
Join us today at 1 pm CST for a lecture by @mariedoyle.bsky.social
Title: Alcohol abstinence precipitates increased alcohol seeking and compulsive intake in association with phenotypic BNST dynamics
bit.ly/3VOJrcy
Title: Alcohol abstinence precipitates increased alcohol seeking and compulsive intake in association with phenotypic BNST dynamics
bit.ly/3VOJrcy
Reposted by Ali Mohebi
The Sosa Lab website is now live!
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
Sosa Lab
www.sosaneurolab.com
September 22, 2025 at 9:23 PM
The Sosa Lab website is now live!
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
www.sosaneurolab.com
We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.
Today 1-2 pm CST bit.ly/3VOJrcy
Join us!
Join us!
Our next speaker is my friend @garrface.bsky.social , who will discuss my favorite topic: Mesolimbic DA --> Causal Learning!
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
September 22, 2025 at 2:40 PM
Today 1-2 pm CST bit.ly/3VOJrcy
Join us!
Join us!
Reposted by Ali Mohebi
🚨Our preprint is online!🚨
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
September 19, 2025 at 1:05 PM
🚨Our preprint is online!🚨
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
www.biorxiv.org/content/10.1...
How do #dopamine neurons perform the key calculations in reinforcement #learning?
Read on to find out more! 🧵
Our next speaker is my friend @garrface.bsky.social , who will discuss my favorite topic: Mesolimbic DA --> Causal Learning!
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
September 19, 2025 at 2:27 PM
Our next speaker is my friend @garrface.bsky.social , who will discuss my favorite topic: Mesolimbic DA --> Causal Learning!
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
Tune in on Monday 9/22 from 1-2pm CST bit.ly/3VOJrcy
Excellent stuff, except that I disagree with #preprint. This is #postprint quality! Congrats to my superstar friend, and the team!
1/
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
🚨 New preprint! 🚨
Excited and proud (& a little nervous 😅) to share our latest work on the importance of #theta-timescale spiking during #locomotion in #learning. If you care about how organisms learn, buckle up. 🧵👇
📄 www.biorxiv.org/content/10.1...
💻 code + data 🔗 below 🤩
#neuroskyence
September 18, 2025 at 4:29 AM
Excellent stuff, except that I disagree with #preprint. This is #postprint quality! Congrats to my superstar friend, and the team!