Matthew J. Smith
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mjtsmith.bsky.social
Matthew J. Smith
@mjtsmith.bsky.social
PhD - Medical Statistician 💊📈

All things Emulated Trials 🍎🍏

#causalsky #statsky #episky
🚨 New paper in Statistics in Medicine!
We compare TMLE vs CV-TMLE in tricky simulations:
✅ Misspecification
✅ Limited overlap
✅ High dimensions
✅ Super Learner + cross-validation

Who performs best?
Read it: onlinelibrary.wiley.com/doi/10.1002/...
#CausalInference #TMLE #CVTMLE
Performance of Cross‐Validated Targeted Maximum Likelihood Estimation
Background Advanced methods for causal inference, such as targeted maximum likelihood estimation (TMLE), require specific convergence rates and the Donsker class condition for valid statistical esti.....
onlinelibrary.wiley.com
July 18, 2025 at 9:31 PM
Reposted by Matthew J. Smith
Excited to be at @lshtm.bsky.social for an event on 'Target trial emulation and other frameworks' hosted by @ruthkeogh.bsky.social of the @lshtm-dash.bsky.social centre!

Seems like the place to be for the UK #EpiSky community!

#TTEsymposium
June 26, 2025 at 8:57 AM
Reposted by Matthew J. Smith
📈 We still have some spaces online for people to join next week's symposium on target trial emulation (TTE) and other frameworks, open to everyone working in #datascience #biostatistics & #clinicaltrials

Sign up 🔽
bit.ly/TTE_25
June 18, 2025 at 3:01 PM
Reposted by Matthew J. Smith
🎫 Spaces still available for our day long event on target-trial emulation and other frameworks

Explore the role and potential of observational data for evaluating the effects of interventions in fields like #datascience #biostatistics #epoidemiology #rstats

Register 🔽
bit.ly/TTE_25
June 13, 2025 at 1:54 PM
Reposted by Matthew J. Smith
👨‍🔬 👩‍🔬 Are you working in #epidemiology #clinicaltrials or research using target trial emulation (TTE)?

Why don’t you join us and your colleagues in London for our symposium, exploring the latest methodological developments and applications of TTE and other frameworks?

Sign up 🔽
bit.ly/TTE_25
June 4, 2025 at 11:13 AM
Reposted by Matthew J. Smith
Reposted by Matthew J. Smith
What is meant by a 'while on treatment' estimand? thestatsgeek.com/2025/03/03/w...
March 3, 2025 at 1:02 PM
The greatest challenge in causal inference?

Incorrectly reading the word "casual".

#causalsky #episky #statsky
January 6, 2025 at 1:12 PM
Very excited to start a new role as a KTP Associate!

Working with @jonathan-bartlett.bsky.social & @ruthkeogh.bsky.social from @lshtm.bsky.social and Aris Perperoglou & Adrian Mander (GSK) to integrate emulated trials at GSK.

Funded by @ukri.org @innovateuk.bsky.social

#causalsky #episky #statsky
January 6, 2025 at 10:12 AM
Reposted by Matthew J. Smith
New updated slide deck of my talk "rage against the machine learning"
www.slideshare.net/slideshow/ra...
Rage Against the Machine Learning - Young Researchers Event
Rage Against the Machine Learning - Young Researchers Event - Download as a PDF or view online for free
www.slideshare.net
December 10, 2024 at 9:28 PM
Reposted by Matthew J. Smith
The 2024-2025 CAUSALAb Methods Series at Karolinska Institutet continues w/ Johan Steen's presentation on immortal time bias.

📆 Nov 26, 2024
⏰ 15.00 CEST/9.00 ET
📍 All Methods Series talks virtual

Register to attend: 👇
stats.sender.net/forms/e7JD1d...

#causalinference #publichealth #causal
November 6, 2024 at 4:42 PM