Mirat Sojitra
@miratsojitra.bsky.social
Cancer Research Institute Postdoctoral Fellow @CarolynBertozzi @Stanford | PhD from @derda_lab @UAlberta | #Glycobiology #PhageDisplay #Siglec
Reposted by Mirat Sojitra
I love this thread by @glycoshape.org, this is @bsky.app at its best!
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
December 11, 2025 at 4:25 PM
I love this thread by @glycoshape.org, this is @bsky.app at its best!
Reposted by Mirat Sojitra
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling
Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...
www.biorxiv.org
December 11, 2025 at 11:34 AM
Super interesting work from @carolynbertozzi.bskyverified.social group about the effects of glycosylation in protein structure and function at the proteome scale 🤯💥🤩
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Results show that sialylation and fucosylation are crucial, which makes a lot of sense. We did some extra bits 🧐 with GlycoShape ⬇️🧵
Congratulations to my very good friend @jfhevler.bsky.social on this amazing pre-print on how mass-spec and MD simulation can enable functional analysis of protein glycoforms. It was a privilege to play a small part in this project and learn a lot from Johannes! #Glycotime #carbohydrate #Proteomics
Congratulations former postdoc @jfhevler.bsky.social (in transit to Roche) and the team on their work using thermal proteome profiling along with glycosylation perturbagens to discover glycan-dependent protein functions at the proteome scale 👏
www.biorxiv.org/content/10.6...
www.biorxiv.org/content/10.6...
Discovering Glycosylation-Dependent Protein Function by Thermal Proteome Profiling
Protein glycosylation regulates essential cellular processes including protein folding, stability, and cell-cell interactions; however, how aberrant glycosylation impacts protein function and interact...
www.biorxiv.org
December 8, 2025 at 4:13 PM
Congratulations to my very good friend @jfhevler.bsky.social on this amazing pre-print on how mass-spec and MD simulation can enable functional analysis of protein glycoforms. It was a privilege to play a small part in this project and learn a lot from Johannes! #Glycotime #carbohydrate #Proteomics
Reposted by Mirat Sojitra
For those who perform thermal proteome profiling (TPP) experiments, you might find this new data analysis approach (and open source Python software) useful. Developed by postdoc @jfhevler.bsky.social 🙏
arxiv.org/abs/2508.096...
arxiv.org/abs/2508.096...
Thermal Tracks: A Gaussian process-based framework for universal melting curve analysis enabling unconstrained hit identification in thermal proteome profiling experiments
Thermal Tracks is a Python-based statistical framework for analyzing protein thermal stability data that overcomes key limitations of existing thermal proteome profiling (TPP) work-flows. Unlike stand...
arxiv.org
October 24, 2025 at 10:18 PM
For those who perform thermal proteome profiling (TPP) experiments, you might find this new data analysis approach (and open source Python software) useful. Developed by postdoc @jfhevler.bsky.social 🙏
arxiv.org/abs/2508.096...
arxiv.org/abs/2508.096...
Reposted by Mirat Sojitra
The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage by Guilherme Meira Lima, @RatmirDerda @derda_lab, et al. at @UAlberta @StanfordUChem @usponline http://dlvr.it/TGL3wR
November 22, 2024 at 8:02 PM
The liquid lectin array detects compositional glycocalyx differences using multivalent DNA-encoded lectins on phage by Guilherme Meira Lima, @RatmirDerda @derda_lab, et al. at @UAlberta @StanfordUChem @usponline http://dlvr.it/TGL3wR