mheming.bsky.social
@mheming.bsky.social
mheming.com
Reposted
This gives a fantastic framing of how to think about reproducibility (it's a spectrum) and how to use renv with intention. Highly recommend, even if you're not using renv, to get a better understanding of how to live in peace as R and package versions advance 🕊️ #rstats
The recording of my #rstats posit::conf talk ✨ practical {renv}✨ is available! 🎉

I created this talk for frustrated {renv} users 🫠 and potential {renv} users🤩

youtu.be/l01u7Ue9pIQ?...

Even if {renv} isn't on your radar, you may still find this talk interesting if you are curious about🤔...
Practical {renv} (Shannon Pileggi, The PCCTC) | posit::conf(2025)
YouTube video by Posit PBC
youtu.be
November 12, 2025 at 5:32 PM
Reposted
Announcing Agent HQ in VS Code: a unified agent experience directly in the editor.

Here's what that looks like...🧵
November 12, 2025 at 6:35 PM
Reposted
Are you looking for a PhD student position in Münster focussing on neuro-immunology of peripheral nerves? Apply
jobs-sf.ukmuenster.de/job/UKM-PhD-...
PhD Student (gn*) in Peripheral Nerve Neurobiology / Neuro-Immunology
PhD Student (gn*) in Peripheral Nerve Neurobiology / Neuro-Immunology
jobs-sf.ukmuenster.de
November 5, 2025 at 10:45 AM
Reposted
R version 4.5.2 "[Not] Part in a Rumble" (source version) has been released. (You can find it in cran.r-project.org/src/base/R-4/, or wait for CRAN to be updated.)
October 31, 2025 at 9:44 AM
Reposted
if someone wants to give feedback on a paper i’ll be submitting soon titled "Nix for Polyglot, Reproducible Data Science Workflows" that’d be greatly appreciated!

github.com/b-rodrigues/...
rix_paper/paper.qmd at master · b-rodrigues/rix_paper
Contribute to b-rodrigues/rix_paper development by creating an account on GitHub.
github.com
October 22, 2025 at 8:59 AM
Reposted
I'm excited to share a new version of the Air formatter for #rstats, with support for tabular formatting! Super useful with `tibble::tribble()` calls or `data.table::fcase()`.

It's currently experimental as we're looking to get feedback on the feature, so please let us know what you think.
October 21, 2025 at 10:34 AM
Reposted
Quarto friends! I need your help:

We are implementing a new QMD parser in Quarto. It will be super nice. But it's a big change, and we want to minimize the impact.

1. Can you share a link to your Quarto project at github.com/quarto-dev/q...
2. repost this and let your Quarto friends know too?
Epic: are we production yet · Issue #63 · quarto-dev/quarto-markdown
We need to check against many large sites to get a good sense for the impact of this new syntax in practice. autogenerated qmd quartodoc-generated sites (tbd meet with @machow) sites quarto.org Shi...
github.com
October 16, 2025 at 2:13 PM
Reposted
🧠 The Lipid #Brain Atlas is out now! If you think #lipids are boring and membranes are all the same, prepare to be surprised. Led by @lucafusarbassini.bsky.social with Giovanni D'Angelo's lab, we mapped membrane lipids in the mouse brain at high resolution.
www.biorxiv.org/cgi/content/...
October 16, 2025 at 6:23 AM
Reposted
New preprint from us: Detection of probable neuronal gene expression changes in skin biopsies from patients with paclitaxel-induced peripheral neuropathy
www.biorxiv.org/content/10.1...
Detection of probable neuronal gene expression changes in skin biopsies from patients with paclitaxel-induced peripheral neuropathy
Our inability to obtain nerve samples from the vast majority of neuropathic pain patients impedes our ability to understand the disease, creates challenges in understanding mechanisms in specific pati...
www.biorxiv.org
October 16, 2025 at 5:13 PM
Reposted
Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data www.nature.com/articles/s4...
October 1, 2025 at 2:15 PM
Reposted
Neuron-reactive KIR+CD8+ T cells display an encephalitogenic transcriptional program in autoimmune encephalitis @natcomms.nature.com
www.nature.com/articles/s41...
September 29, 2025 at 8:21 PM
Reposted
A population of anti-CD20–resistant dural B cells that remain in the mouse brain parenchyma at disease remission in progressive multiple sclerosis @jengommerman.bsky.social @jem.org
rupress.org/jem/article-...
September 18, 2025 at 6:14 PM
Reposted
2024 MS McDonald criteria now published

www.thelancet.com/journals/lan...
www.thelancet.com
September 17, 2025 at 10:57 PM
Reposted
Really insightful post from Julie Tibshirani (spotted in LinkedIn, can't find on Bsky) reflecting on #rstats 's unique governance structure and what can be learned for other languages

jtibs.substack.com/p/if-all-the...
If all the world were a monorepo
The R ecosystem and the case for extreme empathy in software maintenance
jtibs.substack.com
September 14, 2025 at 11:29 PM
Reposted
I was loving Claude Code... until I tried it with #rstats. Constant errors, wouldn't use the tidyverse even when asked, "optimized" functions were slower.

Frustrated, I started a session just to teach R to Claude and summarize what it learned into a CLAUDE.md file gist.github.com/sj-io/3828d6...
Claude R Tidyverse Expert
Claude R Tidyverse Expert. GitHub Gist: instantly share code, notes, and snippets.
gist.github.com
August 21, 2025 at 10:18 AM
Reposted
🚀 v1.104 of VS Code is here! Check out what's new:

🤖 Improved coding agent integration
📄 AGENTS.md file support for better context
🔍 New Auto mode (Preview) for smart model selection
🔑 Model flexibility via BYOK extension API

…and more: aka.ms/VSCodeRelease

Here are the highlights 🧵
September 11, 2025 at 1:41 PM
Reposted
I am beyond excited to announce that ggplot2 4.0.0 has just landed on CRAN.

It's not every day we have a new major #ggplot2 release but it is a fitting 18 year birthday present for the package.

Get an overview of the release in this blog post and be on the lookout for more in-depth posts #rstats
ggplot2 4.0.0
A new major version of ggplot2 has been released on CRAN. Find out what is new here.
www.tidyverse.org
September 11, 2025 at 11:20 AM
Reposted
23 tools to work with (single-cell) TCR/BCR-seq immune repertoire data 🧵 👇
September 8, 2025 at 2:15 PM
Reposted
BOOM! Cool to see the final form of this great work now published. Deep new insight into human peripheral neuropathy. Congrats @mheming.bsky.social and colleagues on a great study.
Very proud that our human PNS atlas is finally published in @natcomms.nature.com We found perineurial hyperplasia and lipid-associated nerve macrophages in #polyneuropathies.
Explore: pns-atlas.mzhlab.com
A tweetorial 1/13
doi.org/10.1038/s414...
August 24, 2025 at 3:21 PM
Reposted
Very impressed with this finding which is quite similar to what we have also seen in DPN nerves. Suggests a completely different disease modifying approach for multiple types of peripheral neuropathy.
12/13
PNPs showed previously unknown perineurial hyperplasia and fibrotic dispersion and this was most pronounced in immune-mediated PNPs.
August 24, 2025 at 3:23 PM
Very proud that our human PNS atlas is finally published in @natcomms.nature.com We found perineurial hyperplasia and lipid-associated nerve macrophages in #polyneuropathies.
Explore: pns-atlas.mzhlab.com
A tweetorial 1/13
doi.org/10.1038/s414...
August 24, 2025 at 1:08 PM
Reposted
Our paper was just published in Nat Comm. First single‑nucleus atlas of human sural nerves in health and disease. Identified lipid‑phagocytosing macrophages and focal perineurial hyperplasia especially in immune-mediated polyneuropathies. rdcu.be/eB2Dg
Multi-omic identification of perineurial hyperplasia and lipid-associated nerve macrophages in human polyneuropathies
Nature Communications - Polyneuropathy causes are difficult to pinpoint. Here, authors used single-nucleus and spatial transcriptomics of 37 human peripheral nerves to identify focal perineurial...
rdcu.be
August 23, 2025 at 12:25 PM
Reposted
Free online ebook: R and python comparisons side by side
www.anotherbookondatascience.com/chapter1.html
August 22, 2025 at 1:45 PM
Reposted
thanks to @mheming.bsky.social for the uv+Nix example and experiments to confirm this could work!
August 20, 2025 at 5:59 PM