Sebastian Andreas Leidel
mcm5s2u.bsky.social
Sebastian Andreas Leidel
@mcm5s2u.bsky.social
RNA Biochemist
Two of the three latest Breakthrough papers in #NAR are from our department. Congrats to @schneian.bsky.social and his amazing team!
December 23, 2025 at 9:02 PM
Our new paper finally in #NAR as Breakthrough paper! Wobble uridine #tRNA modifications have more diverse functions during #translation than previously thought. #tRNA modification defects do not affect all #codons in the same way.
Great work by Jie and Cristian. With help from many.
December 23, 2025 at 8:59 PM
Reposted by Sebastian Andreas Leidel
⭐NAR Breakthrough! ⭐

🔬 #tRNA modifications fine-tune #translation; in yeast, their loss slows #ribosomes at hard-to-read codon pairs, causing collisions ⚠️, and cells deploy quality control pathways to prevent #proteotoxicstress and ensure survival.
🧬Read more: doi.org/10.1093/nar/...
December 23, 2025 at 4:03 PM
tRNA modification and m6A functionally interact in tuning decoding and mRNA decay.
Great collaboration with the Steinmetz lab!
Now out in Cell. Submission date still 2023...

www.sciencedirect.com/science/arti...
May 1, 2025 at 11:14 AM
Reposted by Sebastian Andreas Leidel
Back to the essentials. What a brilliant cartoon!
@nccr-rna-disease.bsky.social
xkcd.com/3056/
RNA
xkcd.com
February 27, 2025 at 8:29 AM
Reposted by Sebastian Andreas Leidel
The 17th Annual Swiss Zebrafish Meeting will take place in Bern on June 5th 2025.
Keynote speakers will be Karina Yaniv and Ken Poss
Registration is open:
swisszebra2025.ch
17th Annual Swiss Zebrafish Meeting – Bern, June 5th 2025
Overview The Swiss Zebrafish Meeting is an annual conference that brings together researchers from various fields of developmental biology, biomedical research,
swisszebra2025.ch
February 13, 2025 at 4:33 PM
The 17th Annual Swiss Zebrafish Meeting will take place in Bern on June 5th 2025.
Keynote speakers will be Karina Yaniv and Ken Poss
Registration is open:
swisszebra2025.ch
17th Annual Swiss Zebrafish Meeting – Bern, June 5th 2025
Overview The Swiss Zebrafish Meeting is an annual conference that brings together researchers from various fields of developmental biology, biomedical research,
swisszebra2025.ch
February 13, 2025 at 4:33 PM