Naomi McGovern
@mcgovernlab.bsky.social
Mononuclear phagocytes in health, disease and pregnancy
Reposted by Naomi McGovern
Calling all postdocs / early career researchers! The Loke CTR Next Generation Fellowship is a stepping stone to research independence!
Visit 🔗 www.trophoblast.cam.ac.uk/next-generat...
Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96
Visit 🔗 www.trophoblast.cam.ac.uk/next-generat...
Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96
October 30, 2025 at 5:31 PM
Calling all postdocs / early career researchers! The Loke CTR Next Generation Fellowship is a stepping stone to research independence!
Visit 🔗 www.trophoblast.cam.ac.uk/next-generat...
Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96
Visit 🔗 www.trophoblast.cam.ac.uk/next-generat...
Need guidance to find a research sponsor? Register your interest via our short form forms.office.com/e/vST36RSB96
Reposted by Naomi McGovern
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
October 2, 2025 at 8:15 AM
Looking to pursue cutting-edge research in early development, maternal-fetal interaction, or placental biology? See 👇
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
- Funded PhD www.trophoblast.cam.ac.uk/phd-students...
- Next Generation Fellowship www.trophoblast.cam.ac.uk/next-generat...
- MPhil www.mphil.bio.cam.ac.uk/mphil-pathwa...
Applications are open for the Next Generation Fellowship – applications until 30 January 2026 www.trophoblast.cam.ac.uk/next-generat...
Next Generation Fellowship Overview | Loke Centre for Trophoblast Research
Next Generation Fellowships The Loke Centre for Trophoblast Research has an established highly-successful program to fund and mentor Next Generation Research Fellowships.
www.trophoblast.cam.ac.uk
October 2, 2025 at 8:40 AM
Applications are open for the Next Generation Fellowship – applications until 30 January 2026 www.trophoblast.cam.ac.uk/next-generat...
Applications are open! For anyone looking to pursue a PhD in cutting-edge research in early development, maternal-fetal interaction, or placental biology: www.trophoblast.cam.ac.uk/phd-students...
PhD Studentships | Loke Centre for Trophoblast Research
The Loke Centre for Trophoblast Research (Loke CTR) offers fully-funded 4-year PhD studentships for home or overseas students The Loke Centre for Trophoblast Research (Loke CTR) provides a dynamic env...
www.trophoblast.cam.ac.uk
October 2, 2025 at 8:39 AM
Applications are open! For anyone looking to pursue a PhD in cutting-edge research in early development, maternal-fetal interaction, or placental biology: www.trophoblast.cam.ac.uk/phd-students...
An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...
The mini placentas and ovaries revealing the basics of women’s health
Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis.
www.nature.com
September 23, 2025 at 8:24 PM
An insight into advances in the field of placental biology and their importance: www.nature.com/articles/d41...
Reposted by Naomi McGovern
Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.
Tissue resident colonic macrophages persist through acute inflammation and adapt to aid tissue repair https://www.biorxiv.org/content/10.1101/2025.09.19.677333v1
September 22, 2025 at 6:48 AM
Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.
Reposted by Naomi McGovern
🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity!
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
TNF and type I interferon crosstalk controls the fate and function of plasmacytoid dendritic cells - Nature Immunology
Plasmacytoid dendritic cells are type 1 interferon (IFN-I)-producing antiviral specialists that have been shown to be able to differentiate into conventional dendritic cells. Here the authors show how...
www.nature.com
September 9, 2025 at 8:14 AM
🚨 New in @natimmunol.nature.com : @idoyagalab.bsky.social shows that plasmacytoid DCs can reprogram into cDC2s after TNF-α stimulation. Fascinating plasticity!
👇
www.nature.com/articles/s41...
👇
www.nature.com/articles/s41...
Reposted by Naomi McGovern
Are you a postdoc interested in the mechanisms of disease?
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Group Leader Career Development Fellowships - Dunn School
Are you an early career researcher interested in the cell or molecular mechanisms underlying disease? Do you have an outstanding record and an innovative research plan?
www.path.ox.ac.uk
September 1, 2025 at 2:39 PM
Are you a postdoc interested in the mechanisms of disease?
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
Do you have a great record and an exciting vision?
Come and start your own lab @dunnschool.bsky.social by applying for sponsorship for early career fellowships.
Deadline 30th September...pass it on!
www.path.ox.ac.uk/work-with-us...
This is a second video shows Listeria monocytogenes (green) recruiting host cell actin (red) in term Hofbauer cells. Created by Nagisa Yoshida
July 21, 2025 at 10:31 AM
This is a second video shows Listeria monocytogenes (green) recruiting host cell actin (red) in term Hofbauer cells. Created by Nagisa Yoshida
Here is a video from our manuscript capturing Hofbauer cells interacting with each other in placental villi explants
July 21, 2025 at 10:28 AM
Here is a video from our manuscript capturing Hofbauer cells interacting with each other in placental villi explants
Happy share this latest study from the team. Here we look at placental macrophage biology across pregnany and their interaction with Listeria monocytogenes.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Interactions between placental Hofbauer cells and L. monocytogenes change throughout gestation
Gestational changes in Hofbauer cells alter their interactions with Listeria monocytogenes.
www.science.org
July 21, 2025 at 8:27 AM
Happy share this latest study from the team. Here we look at placental macrophage biology across pregnany and their interaction with Listeria monocytogenes.
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Naomi McGovern
Congratulations to @drbmalengier.bsky.social, @magmarlene.bsky.social and Team Gentek of @edinuni-irr.bsky.social for this amazing tour de force, comprehensively characterising #synovial #macrophage #development 💪🏻
The synovial lining macrophage layer develops in the first weeks of life in a CSF1- and TGFβ- dependent but monocyte-independent process. https://www.biorxiv.org/content/10.1101/2025.05.21.655269v1
May 26, 2025 at 8:00 PM
Congratulations to @drbmalengier.bsky.social, @magmarlene.bsky.social and Team Gentek of @edinuni-irr.bsky.social for this amazing tour de force, comprehensively characterising #synovial #macrophage #development 💪🏻
Reposted by Naomi McGovern
NIH’s new director Jay Bhattacharya discusses staff morale, grant cuts, and “rumors” in an interview with Science. scim.ag/4mhSMpA
‘It’s been a tough period’: NIH’s new director speaks with Science
Jay Bhattacharya discusses staff morale, grant cuts, and “rumors”
scim.ag
May 6, 2025 at 1:33 PM
NIH’s new director Jay Bhattacharya discusses staff morale, grant cuts, and “rumors” in an interview with Science. scim.ag/4mhSMpA
Reposted by Naomi McGovern
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
April 25, 2025 at 3:57 PM
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Reposted by Naomi McGovern
Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you!
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis
Immune-microbiota interactions are required to maintain host homeostasis. Kim et al.
identified that steady-state sensing of IL-10 by interstitial macrophages (IMs) prevents
spontaneous lung inflammat...
www.cell.com
April 29, 2025 at 3:52 PM
Thrilled to share that our paper is now published in Immunity @cp-immunity.bsky.social ! 🎉 It’s been a long journey, and I’m incredibly grateful to all my co-authors—especially Dr. Teruyuki_Sano—for your dedication. This wouldn’t have been possible without you!
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
April 25, 2025 at 3:57 PM
Want to join us in the field of placental biology? Check out this postdoc position available in my lab in collaboration with Catherin Aiken.
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant/ Research Associate in Placental Biology (Fixed Term) - Job Opportunities - University of Cambridge
Reposted by Naomi McGovern
A new Science study reveals genetic links between pelvic structure and function, locomotion, and childbirth outcomes.
The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb
The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb
The genetic architecture of and evolutionary constraints on the human pelvic form
Human pelvic evolution following the human-chimpanzee divergence is thought to result in an obstetrical dilemma, a mismatch between large infant brains and narrowed female birth canals, but empirical ...
scim.ag
April 16, 2025 at 4:28 PM
A new Science study reveals genetic links between pelvic structure and function, locomotion, and childbirth outcomes.
The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb
The findings offer fresh insights into how our species evolved to balance the competing demands of bipedalism and childbirth. scim.ag/3Y2lQHb
Reposted by Naomi McGovern
🔬 Does your research explore placental ageing, senescence, prolonged pregnancy, or term complications like pre-eclampsia?
Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion.
www.trophoblast.cam.ac.uk/ctrconferenc...
Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion.
www.trophoblast.cam.ac.uk/ctrconferenc...
March 19, 2025 at 2:02 PM
🔬 Does your research explore placental ageing, senescence, prolonged pregnancy, or term complications like pre-eclampsia?
Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion.
www.trophoblast.cam.ac.uk/ctrconferenc...
Join leading experts at our Annual Meeting! Registration open, don’t miss your chance to be part of the discussion.
www.trophoblast.cam.ac.uk/ctrconferenc...
Reposted by Naomi McGovern
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪
How Trump is following Project 2025’s radical roadmap to defund science
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page blueprint. Nature read it so you don’t have to.
go.nature.com
April 4, 2025 at 1:07 AM
Much of the Trump administration’s agenda for research is laid out in the 900-plus-page Project 2025. Nature examines science-related policies from Project 2025 that have already come to pass, and which ones might be on the horizon. 🧪
Reposted by Naomi McGovern
Great to see the abstracts start to come in for EMDS2025.
We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.
We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.
Abstract Submission Open!!
As we slide into the weekend, it's the ideal time to think about your abstract for #EMDS2025. Lots of opportunities for #ECRs to present...and prizes up for grabs!
👉 www.emds2025.com
@britsocimm.bsky.social @cytokinesociety.bsky.social @societymucosalimm.bsky.social
As we slide into the weekend, it's the ideal time to think about your abstract for #EMDS2025. Lots of opportunities for #ECRs to present...and prizes up for grabs!
👉 www.emds2025.com
@britsocimm.bsky.social @cytokinesociety.bsky.social @societymucosalimm.bsky.social
April 4, 2025 at 5:38 AM
Great to see the abstracts start to come in for EMDS2025.
We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.
We have over 20 short talk slots up for grabs - with dedicated slots for #ECRs (PhD and postdocs). So, if you want to showcase your work to Europe's #macrophage #monocyte and #dendriticcell community, be sure to submit your abstract ASAP.
Reposted by Naomi McGovern
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
March 22, 2025 at 12:19 AM
Today I lost an NIH grant training clinicians to do research about intimate partner violence with perinatal women.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
More women are murdered in the perinatal period than die of obstetric complications.
I didn't just lose a grant. We lost an entire cohort of people building careers to prevent that.
Reposted by Naomi McGovern
New research shows that treatment of a rare and often fatal neurodegenerative condition in utero has been a success with the child still symptom free at 2 and a half years. 🧪
Rare genetic disorder treated in womb for the first time
The child, who is now almost three years old, shows no signs of the often fatal motor neuron disease.
www.nature.com
February 21, 2025 at 8:07 AM
New research shows that treatment of a rare and often fatal neurodegenerative condition in utero has been a success with the child still symptom free at 2 and a half years. 🧪
Reposted by Naomi McGovern
The Loke CTR team have worked hard on laboratory sustainability and efficiency and have been awarded LEAF Bronze status as a result!
More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...
More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...
February 12, 2025 at 3:27 PM
The Loke CTR team have worked hard on laboratory sustainability and efficiency and have been awarded LEAF Bronze status as a result!
More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...
More about LEAF (Laboratory Efficiency Assessment Framework) www.ucl.ac.uk/sustainable/...
Reposted by Naomi McGovern
We welcomed @margaridamcm.bsky.social to Cambridge last week. Margarida presented her talk 'The evolution of new cell types and organs: the view from the placenta'. We are very grateful to her for spending the day with us, meeting colleagues and presenting her fascinating research.
February 10, 2025 at 3:11 PM
We welcomed @margaridamcm.bsky.social to Cambridge last week. Margarida presented her talk 'The evolution of new cell types and organs: the view from the placenta'. We are very grateful to her for spending the day with us, meeting colleagues and presenting her fascinating research.
Reposted by Naomi McGovern
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. Nature reports on the search to find out what they do. 🧪
‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. The search is on to find out what they do.
go.nature.com
February 2, 2025 at 5:46 PM
The human genome encodes potentially thousands of tiny proteins that were previously overlooked. Nature reports on the search to find out what they do. 🧪