Marek Brodzki
@mbrodzki.bsky.social
Postdoc in Szczot Lab, Linköping University | 🧠Neuroscience of bodily sensations and perception | Sailing and SUP aficionado | 🇵🇱 living in 🇸🇪 | Views my own.
Inspiring talks & discussion on how to move forward with neuronal classification in the age of multiomic integrations on today's dual perspective at #SfN25. Super important stuff if we want to make real clinical impact. Thanks @vabraira.bsky.social, @tedpricethepainguy.bsky.social and Jeremy Miller!
November 16, 2025 at 8:52 PM
Inspiring talks & discussion on how to move forward with neuronal classification in the age of multiomic integrations on today's dual perspective at #SfN25. Super important stuff if we want to make real clinical impact. Thanks @vabraira.bsky.social, @tedpricethepainguy.bsky.social and Jeremy Miller!
Reposted by Marek Brodzki
#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
June 13, 2025 at 1:33 PM
#neuroskyence folks: as my postdoc grant is running out soon, I am looking for new opportunities in systems neuroscience!
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
Keywords: patch clamp ephys, opto, mouse behavior, (in vivo) voltage imaging. Would love to return to the Basal Ganglia.
Sharing appreciated, and happy #FluorescenceFriday !
@psalmotoxin.bsky.social mesmerized the Linköping Somatosensory crowd with his great research! As photographic evidence suggests, Marcin was euphoric, so was I. Thanks for visiting!
May 15, 2025 at 1:44 PM
@psalmotoxin.bsky.social mesmerized the Linköping Somatosensory crowd with his great research! As photographic evidence suggests, Marcin was euphoric, so was I. Thanks for visiting!
Reposted by Marek Brodzki
An example of what we in the NIH Intramural program can accomplish. Excited to share our latest paper in close collaboration with Nick Ryba's group. We examined how inflammation transforms representation in somatosensory neurons to cause pain. Lots of surprises here: www.nature.com/articles/s41...
www.nature.com
April 23, 2025 at 5:31 PM
An example of what we in the NIH Intramural program can accomplish. Excited to share our latest paper in close collaboration with Nick Ryba's group. We examined how inflammation transforms representation in somatosensory neurons to cause pain. Lots of surprises here: www.nature.com/articles/s41...
Reposted by Marek Brodzki
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Neural ensembles that encode nocifensive mechanical and heat pain in mouse spinal cord - Nature Neuroscience
Zhang et al. identify unimodal neural representations in the spinal cord of cutaneous mechanical and heat stimuli gated by a shared feed-forward local inhibitory neuron type and a neural transition du...
www.nature.com
March 24, 2025 at 4:07 PM
How is the input of the different kinds of primary sensory neurons responding to heat and mechanical stimuli summarized in the spinal cord? Check out our recent study.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Marek Brodzki
Our first release in the attempt to build the Transcription Factor Binding (TFB)-OMICS during #DevBio is now out in Development @dev-journal.bsky.social
doi.org/10.1242/dev....
👉We hope many will use our data, and some will want to help mapping their beloved gene regulators in their favorite tissue
doi.org/10.1242/dev....
👉We hope many will use our data, and some will want to help mapping their beloved gene regulators in their favorite tissue
We are using CUT&RUN-LoV-U to map effectors of Signaling Pathways across tissue and stages of Mouse #DevBio🐭🧬
Do you want to join forces and collaborate to build the future of the TranscriptionFactorBinding(TFB)-OMICS?
www.biorxiv.org/content/10.1...
Do you want to join forces and collaborate to build the future of the TranscriptionFactorBinding(TFB)-OMICS?
www.biorxiv.org/content/10.1...
March 18, 2025 at 7:18 AM
Our first release in the attempt to build the Transcription Factor Binding (TFB)-OMICS during #DevBio is now out in Development @dev-journal.bsky.social
doi.org/10.1242/dev....
👉We hope many will use our data, and some will want to help mapping their beloved gene regulators in their favorite tissue
doi.org/10.1242/dev....
👉We hope many will use our data, and some will want to help mapping their beloved gene regulators in their favorite tissue
Strong agree. The article's title should've been "How to write a quick, shitty review that will frustrate the authors and bring nothing good to the table. Now with AI!"
Let's talk about this Nature piece in more detail.
I've rarely read something so anti-scientific anywhere short of the National Review.
www.nature.com/articles/d41...
I've rarely read something so anti-scientific anywhere short of the National Review.
www.nature.com/articles/d41...
Three AI-powered steps to faster, smarter peer review
Tired of spending countless hours on peer reviews? An AI-assisted workflow could help.
www.nature.com
March 6, 2025 at 8:54 AM
Strong agree. The article's title should've been "How to write a quick, shitty review that will frustrate the authors and bring nothing good to the table. Now with AI!"
Reposted by Marek Brodzki
I really think one of the best things about science is the people you meet along the way. Thanks @mbrodzki.bsky.social,Gabriela, Leandro, Christoffer and Felipe!Especially thanks to @szczotml.bsky.social and Ilona,I really enjoyed all our discussions!
Now, I'm very excited about what's coming next!
Now, I'm very excited about what's coming next!
February 27, 2025 at 1:18 PM
I really think one of the best things about science is the people you meet along the way. Thanks @mbrodzki.bsky.social,Gabriela, Leandro, Christoffer and Felipe!Especially thanks to @szczotml.bsky.social and Ilona,I really enjoyed all our discussions!
Now, I'm very excited about what's coming next!
Now, I'm very excited about what's coming next!
Chatty cortical neurons #FluorescenceFriday
February 21, 2025 at 5:25 PM
Chatty cortical neurons #FluorescenceFriday
Reposted by Marek Brodzki
🚨Check out our new preprint on Bodily Self-dysfunction in #Psychosis, where we look at the Neural and Spinal Response to #Self-produced Sensations using #Touch and #Interoception
@adamenmalm.bsky.social @rkaldewaij.bsky.social @rebeccaboehme.bsky.social #BRNet
🚨 doi.org/10.1101/2025...
1/🧵
@adamenmalm.bsky.social @rkaldewaij.bsky.social @rebeccaboehme.bsky.social #BRNet
🚨 doi.org/10.1101/2025...
1/🧵
Bodily Self-Dysfunction in Psychosis: Altered Neural and Spinal Response to Self-produced Sensations
Psychosis is often characterized by disturbances in the sense of self, with patients frequently misattributing self-produced sensations to external sources. While somatic hallucinations and mispercept...
doi.org
January 29, 2025 at 9:59 AM
🚨Check out our new preprint on Bodily Self-dysfunction in #Psychosis, where we look at the Neural and Spinal Response to #Self-produced Sensations using #Touch and #Interoception
@adamenmalm.bsky.social @rkaldewaij.bsky.social @rebeccaboehme.bsky.social #BRNet
🚨 doi.org/10.1101/2025...
1/🧵
@adamenmalm.bsky.social @rkaldewaij.bsky.social @rebeccaboehme.bsky.social #BRNet
🚨 doi.org/10.1101/2025...
1/🧵
Reposted by Marek Brodzki
Nice writeup on our latest work by NIH Research Matters: Characterizing What Human Sensory Nerves Can Sense! www.nih.gov/news-events/...
Characterizing what human sensory nerves can sense
Researchers analyzed gene activity in different human sensory nerve cells to predict which would respond to stimuli such as heat, cold, and pressure
www.nih.gov
January 12, 2025 at 3:18 PM
Nice writeup on our latest work by NIH Research Matters: Characterizing What Human Sensory Nerves Can Sense! www.nih.gov/news-events/...
Reposted by Marek Brodzki
BOOM! Identification of a PIEZO2+, KIT+, and TRPM8+ A fiber nociceptor subtype that is responsible for human hair pull pain: www.researchsquare.com/article/rs-5... @saadnagi.bsky.social and colleagues, well done!
PIEZO2-dependent rapid pain system in humans.
The diversity of mechanical pain sensations in humans cannot be explained based on our current understanding of pain-sensing neural classes in the skin. To begin to bridge this gap, we dissected the n...
www.researchsquare.com
December 9, 2024 at 12:53 AM
BOOM! Identification of a PIEZO2+, KIT+, and TRPM8+ A fiber nociceptor subtype that is responsible for human hair pull pain: www.researchsquare.com/article/rs-5... @saadnagi.bsky.social and colleagues, well done!
Very clever biophysical trickery used to modulate TRPV1 channels in models of inflammatory pain. Cool and innovative🧠 #painresearch !
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Solvent-mediated analgesia via the suppression of water permeation through TRPV1 ion channels - Nature Biomedical Engineering
TRPV1 ion channels allow for water flow through them and their activity can be suppressed by downregulating the permeation of cations through the channels via the administration of deuterated water.
www.nature.com
November 28, 2024 at 9:20 AM
Very clever biophysical trickery used to modulate TRPV1 channels in models of inflammatory pain. Cool and innovative🧠 #painresearch !
www.nature.com/articles/s41...
www.nature.com/articles/s41...