Mayuri Sadoine 🧫🌿🔬
@mayurisadoine.bsky.social
Tenure-Track Junior Professor (she/her) I Chair on Interactions between Plants, Microbes & the Environment
#Biosensors #NewPI #ClimateActions🇪🇺🇺🇦
websites: https://mayurisadoine.academicwebsite.com; https://spmir-group.academicwebsite.com
#Biosensors #NewPI #ClimateActions🇪🇺🇺🇦
websites: https://mayurisadoine.academicwebsite.com; https://spmir-group.academicwebsite.com
Reposted by Mayuri Sadoine 🧫🌿🔬
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
A ubiquitin-like protein controls assembly of a bacterial type VIIb secretion system
Cryo-EM structure reveals how a ubiquitin-like protein orchestrates assembly of a bacterial weapon system.
www.science.org
November 21, 2025 at 7:05 PM
Our latest T7SS study is now out in Science Advances!
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
We solved the cryoEM structure of the T7SSb core unit (T7bCU) composed of YukB, YukC, and YukD from Bacillus subtilis, revealing how these components assemble within the secretion machinery.
www.science.org/doi/10.1126/...
Reposted by Mayuri Sadoine 🧫🌿🔬
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Helixer: ab initio prediction of primary eukaryotic gene models combining deep learning and a hidden Markov model - Nature Methods
By leveraging both deep learning and hidden Markov models, Helixer achieves broad taxonomic coverage for ab initio gene annotation of eukaryotic genomes from fungi, plants, vertebrates and invertebrat...
www.nature.com
November 26, 2025 at 6:00 AM
AI model Helixer predicts eukaryotic genes ab initio, directly from a plain text FASTA file.
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
No RNA-seq.
No protein homology.
No repeats, hints, or curated evidence.
Raw genome → accurate gene models.
Deep learning + HMM, published in @natmethods.nature.com
www.nature.com/articles/s41...
Reposted by Mayuri Sadoine 🧫🌿🔬
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Next generation of 1001 Genomes Plus browser and data download
Please indicate all features you would like to see in a browser that displays features of completely sequenced Arabidopsis thaliana genomes
docs.google.com
November 24, 2025 at 2:49 PM
We (Nordborg & Weigel labs) need input on the next generation of genome browsers & data download modes for the #Arabidopsis #1001GenomesPlus project. We have now a curated collection of over 500 long read genomes.
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Please help us by filling out this questionnaire: docs.google.com/forms/d/e/1F...
Reposted by Mayuri Sadoine 🧫🌿🔬
To all visionary microbe enthusiasts: @femsmicro.org is looking for an editor-in-chief for their flagship journal FEMS Microbiology Reviews! More details can be found here: fems-microbiology.org/opportunitie...
Editor-in-Chief for FEMS Microbiology Reviews - FEMS
The Federation of European Microbiological Societies (FEMS) is looking for an Editor-in-Chief to join its prestigious journal FEMS Microbiology Reviews for an initial period of three years, starting i...
fems-microbiology.org
November 5, 2025 at 5:38 PM
To all visionary microbe enthusiasts: @femsmicro.org is looking for an editor-in-chief for their flagship journal FEMS Microbiology Reviews! More details can be found here: fems-microbiology.org/opportunitie...
Reposted by Mayuri Sadoine 🧫🌿🔬
Optimizing our plant imaging protocol and having fun along the way 😜
November 23, 2025 at 3:55 PM
Optimizing our plant imaging protocol and having fun along the way 😜
Reposted by Mayuri Sadoine 🧫🌿🔬
“The ZAT14 family promotes cell death and regulates expansins to affect xylem formation and salt tolerance in Arabidopsis”. Now out in @theplantcell.bsky.social led by Ming Feng and colleagues. A 🌱 thread 👇 1/x
academic.oup.com/plcell/advan...
academic.oup.com/plcell/advan...
November 23, 2025 at 9:13 PM
“The ZAT14 family promotes cell death and regulates expansins to affect xylem formation and salt tolerance in Arabidopsis”. Now out in @theplantcell.bsky.social led by Ming Feng and colleagues. A 🌱 thread 👇 1/x
academic.oup.com/plcell/advan...
academic.oup.com/plcell/advan...
Reposted by Mayuri Sadoine 🧫🌿🔬
It’s finally out! 🎉
Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social
AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth.
🔗 www.pnas.org/doi/10.1073/...
#PlantSciences
Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social
AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth.
🔗 www.pnas.org/doi/10.1073/...
#PlantSciences
An AINTEGUMENTA phosphoswitch controls bilateral stem cell activity during secondary growth | PNAS
Plant stem cells have the remarkable ability to give rise to distinct tissues and
organs throughout development. Two concentric cylinders of active...
www.pnas.org
November 20, 2025 at 9:07 PM
It’s finally out! 🎉
Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social
AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth.
🔗 www.pnas.org/doi/10.1073/...
#PlantSciences
Work led by former PhD student @wei-xiao-botany.bsky.social , in collaboration with @bayerlab.bsky.social and @bertderybel.bsky.social
AINTEGUMENTA phospho-switch regulates bilateral stem cell activity during secondary growth.
🔗 www.pnas.org/doi/10.1073/...
#PlantSciences
Reposted by Mayuri Sadoine 🧫🌿🔬
I recently moved my lab to Purdue University and am looking for graduate students. We are working at the interface of population genomics, quantitative genetics and functional genomics to understand how plants adapt to extreme environments. Reach out if you would like to discuss potential projects.
November 8, 2025 at 3:42 PM
I recently moved my lab to Purdue University and am looking for graduate students. We are working at the interface of population genomics, quantitative genetics and functional genomics to understand how plants adapt to extreme environments. Reach out if you would like to discuss potential projects.
Reposted by Mayuri Sadoine 🧫🌿🔬
The department of biologie #usherbrooke is hiring. Faculty position open in the area of #Plant Molecular and Cellular Biology.
www.usherbrooke.ca/emplois/offr...
www.usherbrooke.ca/emplois/offr...
Professeure ou professeur en biologie moléculaire végétale
Offre d'emploi : Professeure ou professeur en biologie moléculaire végétale, Sherbrooke, Campus principal, Université de Sherbrooke
www.usherbrooke.ca
November 18, 2025 at 8:00 PM
The department of biologie #usherbrooke is hiring. Faculty position open in the area of #Plant Molecular and Cellular Biology.
www.usherbrooke.ca/emplois/offr...
www.usherbrooke.ca/emplois/offr...
Reposted by Mayuri Sadoine 🧫🌿🔬
We found that cytokinin-induced LBDs drive radial (secondary) growth in Arabidopsis root by reshaping primary cell wall pectin, in part through four pectate-lyase-like genes. Huge congrats to the fantastic postdocs who led this work: Lingling Ye and Xin Wang. 1/x www.nature.com/articles/s41...
Cambium LBDs promote radial growth by regulating PLL-mediated pectin metabolism - Nature Plants
This study reveals that LBD transcription factors in the cambium drive radial plant growth by regulating PECTATE LYASE-LIKE (PLL) enzymes that remodel cell wall pectin, promoting cell expansion.
www.nature.com
November 17, 2025 at 7:11 PM
We found that cytokinin-induced LBDs drive radial (secondary) growth in Arabidopsis root by reshaping primary cell wall pectin, in part through four pectate-lyase-like genes. Huge congrats to the fantastic postdocs who led this work: Lingling Ye and Xin Wang. 1/x www.nature.com/articles/s41...
Reposted by Mayuri Sadoine 🧫🌿🔬
The University of Toulouse has 44 postdoc positions to fill (Horizon Europe MSCA-COFUND). My lab is looking for candidates to apply and work on how plants regulate cell surface levels of receptors or transporters in response to heat. Please DM me if interested!
tiris.univ-toulouse.fr/en/programs/...
tiris.univ-toulouse.fr/en/programs/...
AToUT – TIRIS – Toulouse's Science In and For Society
tiris.univ-toulouse.fr
November 12, 2025 at 3:26 PM
The University of Toulouse has 44 postdoc positions to fill (Horizon Europe MSCA-COFUND). My lab is looking for candidates to apply and work on how plants regulate cell surface levels of receptors or transporters in response to heat. Please DM me if interested!
tiris.univ-toulouse.fr/en/programs/...
tiris.univ-toulouse.fr/en/programs/...
Reposted by Mayuri Sadoine 🧫🌿🔬
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
November 6, 2025 at 6:51 PM
Plz RP. Come join us at @slcuplants.bsky.social @cam.ac.uk to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
Reposted by Mayuri Sadoine 🧫🌿🔬
1/ It is my pleasure to share the latest preprint of the team: "Symbiotic diversification relies on an ancestral gene network in plants"
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
Symbiotic diversification relies on an ancestral gene network in plants
Symbioses have been fundamental to colonization of terrestrial ecosystems by plants and their evolution. Emergence of the ancient arbuscular mycorrhizal symbiosis was followed by the diversification o...
doi.org
November 4, 2025 at 8:06 AM
1/ It is my pleasure to share the latest preprint of the team: "Symbiotic diversification relies on an ancestral gene network in plants"
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
doi.org/10.1101/2025...
Here, we identified and functionally validated a novel master regulator of intracellular symbioses!
A thread ...
#PlantScience
Reposted by Mayuri Sadoine 🧫🌿🔬
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de
November 2, 2025 at 10:27 AM
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
jobportal.uni-koeln.de/ausschreibun...
Reposted by Mayuri Sadoine 🧫🌿🔬
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu
October 31, 2025 at 9:24 AM
📢 Open Call! The Max Perutz Labs invite applications for a Full Professorship in Integrative Structure Biology with a focus on in situ structural biology using cryo-electron tomography (cryo-ET) and related methods. More details ➡️ tinyurl.com/brswbymu
Reposted by Mayuri Sadoine 🧫🌿🔬
This Halloween, we have a spooky evolutionary story for you.
The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
October 31, 2025 at 10:19 AM
This Halloween, we have a spooky evolutionary story for you.
The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
The brainchild of @delaconcepcionjc.bsky.social, Nick Irwin and our fantastic collaborators is now out in @natplants.nature.com www.nature.com/articles/s41...
Here’s why I love this work — and why I think you’ll enjoy it too. 👇
Reposted by Mayuri Sadoine 🧫🌿🔬
🌿🌱 We’re hiring a tenure-track Assistant Professor (potentially open rank) at the Institute of Plant Sciences
@unibe.ch in Plant Population Ecology 🌻🌳
Be our colleague and join us in beautiful Bern, Switzerland
Apply by Jan 23 2026 👉 ohws.prospective.ch/public/v1/jo...
@unibe.ch in Plant Population Ecology 🌻🌳
Be our colleague and join us in beautiful Bern, Switzerland
Apply by Jan 23 2026 👉 ohws.prospective.ch/public/v1/jo...
October 30, 2025 at 3:55 PM
🌿🌱 We’re hiring a tenure-track Assistant Professor (potentially open rank) at the Institute of Plant Sciences
@unibe.ch in Plant Population Ecology 🌻🌳
Be our colleague and join us in beautiful Bern, Switzerland
Apply by Jan 23 2026 👉 ohws.prospective.ch/public/v1/jo...
@unibe.ch in Plant Population Ecology 🌻🌳
Be our colleague and join us in beautiful Bern, Switzerland
Apply by Jan 23 2026 👉 ohws.prospective.ch/public/v1/jo...
Reposted by Mayuri Sadoine 🧫🌿🔬
📣 Now announcing the journal publication 📄 of our work in @newphyt.bsky.social on how Verticillium undermines the plant's 🌱 "cry for help": terrific work by @antonkraege.bsky.social & @wolki95.bsky.social doi.org/10.1111/nph....
Undermining the cry for help: the phytopathogenic fungus Verticillium dahliae secretes an antimicrobial effector protein to undermine host recruitment of antagonistic Pseudomonas bacteria
During pathogen attack, plants recruit beneficial microbes in a ‘cry for help’ to mitigate disease development. Simultaneously, pathogens secrete effectors to promote host colonisation through vario...
doi.org
October 30, 2025 at 8:47 AM
📣 Now announcing the journal publication 📄 of our work in @newphyt.bsky.social on how Verticillium undermines the plant's 🌱 "cry for help": terrific work by @antonkraege.bsky.social & @wolki95.bsky.social doi.org/10.1111/nph....
Reposted by Mayuri Sadoine 🧫🌿🔬
New lab / new life 🌱
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
October 29, 2025 at 2:46 PM
New lab / new life 🌱
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
The Julian Lab is now open at the Institute of Molecular Plant Biology (IMPB), BOKU University 🇦🇹
We explore how plants defend their vacuoles and how vacuoles defend them! 🛡️
Excited to collaborate with @angegross.bsky.social’s lab.
#PlantBiology #Vacuole #VQC #BOKU #IMPB
Reposted by Mayuri Sadoine 🧫🌿🔬
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
Uncoupling hypersensitive cell death response and disease resistance activated by effector-triggered immunity https://www.biorxiv.org/content/10.1101/2025.10.22.683861v1
October 23, 2025 at 11:51 PM
Humbly share our latest work led by @himanshuchhillar.bsky.social my phd student
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
And thanks to all collaborators Henk-jan @brunongou.bsky.social @jonathandgjones.bsky.social
Reposted by Mayuri Sadoine 🧫🌿🔬
Final, edited version of the paper now available
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
October 25, 2025 at 12:27 PM
Final, edited version of the paper now available
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Reposted by Mayuri Sadoine 🧫🌿🔬
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
Differential contributions of an antimicrobial effector from Verticillium dahliae to virulence and tomato microbiota assembly across natural soils https://www.biorxiv.org/content/10.1101/2025.09.30.679524v1
October 14, 2025 at 8:05 PM
📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
Reposted by Mayuri Sadoine 🧫🌿🔬
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Primary metabolism underpins the execution of immune responses in different tissues of the same plant https://www.biorxiv.org/content/10.1101/2025.10.11.681807v1
October 14, 2025 at 7:16 AM
New pre-print from the team!
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
The manuscript is @emma-raven.bsky.social's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses.
Have a read!
#PlantScience
@johninnescentre.bsky.social
Reposted by Mayuri Sadoine 🧫🌿🔬
New PhD opportunity in my group @thesainsburylab.bsky.social through the BBSRC NRP DTP Programme - see details of host to apply below
biodtp.norwichresearchpark.ac.uk/projects/van...
biodtp.norwichresearchpark.ac.uk/projects/van...
Vanishing Virulence: Investigating pathogenicity loss in a plant pathogenic fungus (TALBOT_T26DTP) | Doctoral Training Partnership
What makes a plant killer lose its edge? This project will investigate why fungal pathogens lose virulence when they are grown in laboratory culture away from their host plant. Use cutting-edge…
biodtp.norwichresearchpark.ac.uk
October 12, 2025 at 5:20 PM
New PhD opportunity in my group @thesainsburylab.bsky.social through the BBSRC NRP DTP Programme - see details of host to apply below
biodtp.norwichresearchpark.ac.uk/projects/van...
biodtp.norwichresearchpark.ac.uk/projects/van...