Matt Harkey, PhD
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mattharkeyphd.bsky.social
Matt Harkey, PhD
@mattharkeyphd.bsky.social
🦵 Researching why patients after knee injury are at 📈risk for arthritis 🧪

🔎 Early OA Detection •🩻 Ultrasound Imaging •⚙️ Biomechanics

Assistant Professor • Michigan State University 🏛️
Director • Athletic Injuries & Rehabilitation (AIR) Labs
Pinned
🦋 Hello from AIR Labs! 🧪 We study how movement impacts knee OA after injury. Our research focuses on:

🏋️‍♂️ Biomechanics
🏃 Physical Activity
🩻 Structural Changes
📊 Early Symptoms

👍Our goal? Early detection & prevention of OA.

😁Excited to share & connect! #Ultrasound #Osteoarthritis #ACL #KneeHealth
What. A. Day.💥

🦴The inaugural @henryfordhealth.bsky.social
+ @michiganstateu.bsky.social Musculoskeletal Research Retreat was an incredible success!

🤝~90 attendees from both institutions came together to build connections, share ideas, and spark collaboration.

➡️https://lnkd.in/eGK6VqNj
June 20, 2025 at 4:43 PM
Pumped to see our team’s work on early inflammatory changes following knee surgery take center stage at #ACSM25 today! 🧠🗣️🔥

We’re showcasing how ultrasound gives us a clearer view into joint health and recovery after ACLR. 🔬🦵📈

Just getting started 💪📊
#OA #sportsmed #ACLR #ultrasound
May 28, 2025 at 12:47 PM
Reposted by Matt Harkey, PhD
Excited to attend the American College of Sports Medicine #ACSM25 meeting in Atlanta this week! Meet us at Booth 802 and check out how our new #pedar with lightweight #plidar technology can help advance your #sports and #biomechanics applications!

For more information, visit www.novelusa.com/pedar
May 27, 2025 at 2:18 PM
🚨 Now recruiting 2 PhD students @ MSU!

Join a funded study investigating early arthritis after knee surgery using:

– 🖥️ Ultrasound imaging
– 🦵 Movement biomechanics
– 🧠 Psychological & hormonal factors

📍: East Lansing, MI
📩: harkeym1@msu.edu | hartharv@msu.edu
📸 Flyer below 👇
May 6, 2025 at 5:58 PM
Reposted by Matt Harkey, PhD
Excited to share our work on the small but mighty microRNA-126-3p in @naturecomms.bsky.social! We found this microRNA is elevated in four knee osteoarthritis cohorts and show in an animal model that it reduces the severity of knee osteoarthritis - at least in part via angiogenesis. rdcu.be/ebycj
February 27, 2025 at 7:23 PM
📢 New research challenges BMI as a predictor of ACL recovery. Instead, body composition—lean vs. fat mass—better correlates with strength & function.

🔬 DXA showed:
✅ More lean mass → Stronger quads, better mobility
❌ More fat mass → Worse knee pain & performance
📉 BMI? No significant correlation.
February 18, 2025 at 11:27 AM
📢 Interesting study in Orthopaedic Journal of Sports Medicine 🦵🔬: Among 16,935 pediatric ACL reconstructions, 1.6% developed PTOA within 5 years.

Key risk factors:
⚠️ Motion restoration surgery (OR = 5.0)
👶 Age ≤12 (OR = 4.8)
⏳ Delayed ACLR (OR = 1.8)
⚖️ Obesity (OR = 1.4)
⚡ Male sex (OR = 1.3)
February 18, 2025 at 12:30 AM
🚨 NIH funding is at risk! 🚨

📢 Indirect cost rate changes could slow down life-saving medical research that patients depend on! ❤️🔬🧪

@aimbe-official made it easy to take action! 📩 Send a letter to Congress in under 1 minute! ⏳🏛️

🔗 Act now: aimbe.org/advocate/wri…

📢 Spread the word#ScienceMattersrs
February 11, 2025 at 2:34 AM
Reposted by Matt Harkey, PhD
Thanks for this. I linked this thread in my Substack and made a script for people to use to contact their reps!

fromthescienceclass.substack.com/p/biomedical...
Biomedical Research Under Threat: Urge Congress to Act Now!
A Friday evening plea from a concerned scientist
fromthescienceclass.substack.com
February 8, 2025 at 3:04 AM
🚨 NIH’s indirect cost policy might not stick. 🧪

Turns out, there’s already a law preventing NIH from making these changes without congressional approval.

Hopefully there’s a good chance this IDC change won’t move forward as planned. Something to watch! 👀
February 8, 2025 at 3:16 AM
🔬 NIH’s new policy to cap indirect costs at 15% is a major blow to research institutions. 🧪

💰 Less funding for operations = fewer resources for science.
⚠️ Small institutions may struggle to sustain research.
🏛️ This could impact the future of NIH-funded projects.

🔗 grants.nih.gov/grants/guide...
NOT-OD-25-068: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Supplemental Guidance to the 2024 NIH Grants Policy Statement: Indirect Cost Rates NOT-OD-25-068. OD
grants.nih.gov
February 7, 2025 at 11:54 PM
🏆 Wireless ultrasound is a game-changer!

🔬 Our new study in Osteoarthritis Imaging confirms that Clarius wireless ultrasound probes accurately measure knee cartilage thickness—comparable to traditional systems.

📊 A big step toward more accessible ultrasound technology!

🔗: doi.org/10.1016/j.os...
February 6, 2025 at 10:55 PM
Reposted by Matt Harkey, PhD
Excited to share the first paper from my PhD in @kelseyhcollins.bsky.social lab where we show that IPFP images using MRI are related to pain and are different with age, obesity and sex. Collab with ⁦Richard Souza, Laura Chen, and ⁦Emma Nedley.

onlinelibrary.wiley.com/doi/10.1002/...
Relationships Between the Infrapatellar Fat Pad and Patellofemoral Joint Osteoarthritis Differ With Body Mass Index and Sex
Investigating the relationship between the infrapatellar fat pad (IPFP) and patellofemoral joint osteoarthritis (PFJOA), split up into outcomes of structural changes and functional changes, using MRI....
onlinelibrary.wiley.com
January 27, 2025 at 8:56 PM
🦋 Hello from AIR Labs! 🧪 We study how movement impacts knee OA after injury. Our research focuses on:

🏋️‍♂️ Biomechanics
🏃 Physical Activity
🩻 Structural Changes
📊 Early Symptoms

👍Our goal? Early detection & prevention of OA.

😁Excited to share & connect! #Ultrasound #Osteoarthritis #ACL #KneeHealth
February 2, 2025 at 8:11 PM
Reposted by Matt Harkey, PhD
I have started an Orthopaedic Research Starter Pack! Link: go.bsky.app/61hCir6. I am happy to add people -- comment below to be added!
November 19, 2024 at 12:46 AM
🚨 Ultrasound + Bone Shape = New Research! 🚨

We developed a novel B-Score 🧮 using an ultrasound-based statistical shape model 🩻 to measure femoral bone shape post-ACLR 🦵
✅ Accessible
✅ Accurate (92%!)
✅ Early detection potential
📖 Full study 👉shorturl.at/lto3A
February 1, 2025 at 5:04 AM