marinanikolova.bsky.social
@marinanikolova.bsky.social
Reposted
Now online! Fate and state transitions during human blood vessel organoid development
Fate and state transitions during human blood vessel organoid development
Single-cell multiomic reconstruction of the human blood vessel organoid system allows for classifying and modeling disease and cell-type-specific states, demonstrating its potential for translational research.
dlvr.it
April 17, 2025 at 6:51 PM
Reposted
Drs. Marina Nikolova, Barbara Treutlein, the @graycamplab.bsky.social, and a team at @ethzurich.bsky.social used multiomic #SingleCell analysis to reconstruct blood vessel organoid development! 🩸

@cellpress.bsky.social paper: bit.ly/3GstKTZ
Discussion: bit.ly/4jWDX9T
May 7, 2025 at 3:39 PM
Reposted
Yay, we built a thing! With @dominik1klein.bsky.social Daniil, Aviv Regev, Barbara Treutlein @graycamplab.bsky.social @fabiantheis.bsky.social we use flow matching to enable generalised sc phenotype modeling. From cytokine screens to fate programming and organoid engineering tinyurl.com/3xhju7db
CellFlow enables generative single-cell phenotype modeling with flow matching
High-content phenotypic screens provide a powerful strategy for studying biological systems, but the scale of possible perturbations and cell states makes exhaustive experiments unfeasible. Computatio...
www.biorxiv.org
April 18, 2025 at 10:19 AM
Reposted
Excited to share our latest preprint, presenting a multi-omic human neural organoid cell atlas of the posterior brain! 🧠🔬
doi.org/10.1101/2025...
Great work with @hsiuchuanlin.bsky.social @zhisonghe.bsky.social @graycamplab.bsky.social and Barbara Treutlein!
March 24, 2025 at 12:42 PM
Reposted
It was fun to learn about blood vessel organoids together with @marinanikolova.bsky.social and Barbara Treutlein! Thanks to Reiner Wimmer and @penningerlab.bsky.social for introducing us to this system! www.cell.com/cell/fulltex... Great support from editors and reviewers @cellpress.bsky.social!
April 28, 2025 at 2:33 PM
Happy to share our resource for blood vessel organoids!
@zhisonghe.bsky.social, Makiko Seimiya, Gustav Jonsson, Wuji Cao, Ryo Okuda, Reiner Wimmer, Ryoko Okamoto
Barbara Treutlein, @graycamplab.bsky.social, @penningerlab.bsky.social
April 21, 2025 at 6:39 PM