Marcos Aranda
@marcosaranda.bsky.social
Studying effects of light on physiology and behavior | Postdoc at the Schmidt lab | Northwestern University
Pinned
Marcos Aranda
@marcosaranda.bsky.social
· Sep 30
Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior
Nature Communications - This study reveals that graded expression of the transcription factor BRN3B fine-tunes the identity and function of melanopsin-expressing ipRGC subtypes in the retina....
urldefense.com
Our paper is out today! In @tiffmschmidt.bsky.social lab, we identified a single transcription factor, BRN3B, that shapes multiple, key features that define diverse ipRGC subtypes🧬👁️🐭
Reposted by Marcos Aranda
Delighted to share our latest preprint. It's been a long time coming. Thanks to all the authors for their unique contribution and for for their patience. We show how the visual thalamus deals with active and passive head motion in freely moving animals: www.biorxiv.org/content/10.1...
Efficient mixed representation of active and passive motion in the mouse visual thalamus during natural behaviour
During natural behaviour, changes in the visual scene are largely driven by the subject’s own movements, which can be actively generated (e.g., walking) or passively imposed by external forces (e.g., ...
www.biorxiv.org
November 9, 2025 at 3:43 PM
Delighted to share our latest preprint. It's been a long time coming. Thanks to all the authors for their unique contribution and for for their patience. We show how the visual thalamus deals with active and passive head motion in freely moving animals: www.biorxiv.org/content/10.1...
Thank you for the invitation @weillcornell.bsky.social! Fantastic discussions and inspiring colleagues!
November 8, 2025 at 3:25 AM
Thank you for the invitation @weillcornell.bsky.social! Fantastic discussions and inspiring colleagues!
Reposted by Marcos Aranda
We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy.
November 4, 2025 at 10:20 AM
We’re hiring! Join the Sivyer Lab at The University of Sydney as a Postdoctoral Research Fellow in Neurodegeneration within the Snow Vision Accelerator, a $50M initiative tackling glaucoma and optic nerve disease. iPSCs, electrophysiology, drug discovery, and gene therapy.
Reposted by Marcos Aranda
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Zebrafish use spectral information to suppress the visual background
Vertebrate eyes first evolved in water, where spectral content rapidly fades with
distance. Zebrafish exploit this loss by antagonizing cone signals to suppress the
background, pointing to distance es...
www.cell.com
November 4, 2025 at 9:16 AM
Excited to share our paper now published in Cell!
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
'Zebrafish use spectral information to suppress the visual background'
Huge thanks to @neurofishh.bsky.social & @teuler.bsky.social
@cellpress.bsky.social @cp-cell.bsky.social
👇🏻
www.cell.com/cell/fulltex...
Reposted by Marcos Aranda
Two new papers to... er... skeet? Blurt? Bluert?
First is that our paper on the transcription factor Adnp and the ChAHP chromatin remodelling complex is now out.
www.pnas.org/doi/10.1073/...
I already blurted the paper here: bsky.app/profile/pier...
First is that our paper on the transcription factor Adnp and the ChAHP chromatin remodelling complex is now out.
www.pnas.org/doi/10.1073/...
I already blurted the paper here: bsky.app/profile/pier...
January 18, 2025 at 12:46 PM
Two new papers to... er... skeet? Blurt? Bluert?
First is that our paper on the transcription factor Adnp and the ChAHP chromatin remodelling complex is now out.
www.pnas.org/doi/10.1073/...
I already blurted the paper here: bsky.app/profile/pier...
First is that our paper on the transcription factor Adnp and the ChAHP chromatin remodelling complex is now out.
www.pnas.org/doi/10.1073/...
I already blurted the paper here: bsky.app/profile/pier...
Reposted by Marcos Aranda
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Retinal glia regulate development of the circadian photoentrainment circuit
Circadian photoentrainment depends on intrinsically photosensitive retinal ganglion cells (ipRGCs), which convey environmental light information to th…
www.sciencedirect.com
October 29, 2025 at 2:27 PM
Our latest paper is out! While the circadian photoentrainment circuit has been extensively studied, the mechanisms regulating its development remain poorly understood. Here we show that retinal Müller glia play a key role in this process. Check it out! www.sciencedirect.com/science/arti...
Reposted by Marcos Aranda
£250 Visual Art Prize Competition!
We're looking for art work to represent our research on sleep & mental health. Deadline: 31st December!
More info here: www.sleepengineering.co.uk/art-call-out
We're looking for art work to represent our research on sleep & mental health. Deadline: 31st December!
More info here: www.sleepengineering.co.uk/art-call-out
October 29, 2025 at 3:30 PM
£250 Visual Art Prize Competition!
We're looking for art work to represent our research on sleep & mental health. Deadline: 31st December!
More info here: www.sleepengineering.co.uk/art-call-out
We're looking for art work to represent our research on sleep & mental health. Deadline: 31st December!
More info here: www.sleepengineering.co.uk/art-call-out
Reposted by Marcos Aranda
#Circadian #medicine tests if treatment timing can improve patient outcomes. This paper by @mariafelicita.bsky.social @oliviawalch.bsky.social et al considers #chronodiagnostics ...how the outcome of a standard test for glioblastoma differs with time of biopsy. link.springer.com/article/10.1...
Circadian variation in MGMT promoter methylation and expression predicts sensitivity to temozolomide in glioblastoma - Journal of Neuro-Oncology
Purpose Recent studies show that glioblastoma (GBM) is more sensitive to temozolomide (TMZ) in the morning. In cells, inhibiting O6-Methylguanine-DNA-Methyltransferase (MGMT) abolished time-dependent ...
link.springer.com
October 22, 2025 at 1:04 PM
#Circadian #medicine tests if treatment timing can improve patient outcomes. This paper by @mariafelicita.bsky.social @oliviawalch.bsky.social et al considers #chronodiagnostics ...how the outcome of a standard test for glioblastoma differs with time of biopsy. link.springer.com/article/10.1...
Reposted by Marcos Aranda
For your enjoyment (by @jagarikin)
October 25, 2025 at 11:58 AM
For your enjoyment (by @jagarikin)
Reposted by Marcos Aranda
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
October 22, 2025 at 10:44 PM
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
Nice to find my research images decorating the department offices 🙂
October 21, 2025 at 3:33 PM
Nice to find my research images decorating the department offices 🙂
Reposted by Marcos Aranda
Teresa Puthussery, a UC Berkeley vision scientist whose insights into the retina could one day help those with vision loss regain their sight, has been named a 2025 MacArthur “genius” Fellow. news.berkeley.edu/2025/10/08/v...
Vision scientist Teresa Puthussery receives MacArthur ‘genius’ award - Berkeley News
Puthussery’s discoveries about the retina are paving the way for new treatments for eye disease and vision loss
news.berkeley.edu
October 8, 2025 at 9:48 PM
Teresa Puthussery, a UC Berkeley vision scientist whose insights into the retina could one day help those with vision loss regain their sight, has been named a 2025 MacArthur “genius” Fellow. news.berkeley.edu/2025/10/08/v...
Reposted by Marcos Aranda
Introducing CellTransformer, a new AI tool developed with UCSF that makes it easier to explore massive neuroscience datasets and identify important subregions of the brain. 🧵
October 7, 2025 at 5:16 PM
Introducing CellTransformer, a new AI tool developed with UCSF that makes it easier to explore massive neuroscience datasets and identify important subregions of the brain. 🧵
Reposted by Marcos Aranda
🚨 New preprint out from our lab!
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
The Rod Bipolar Cell Pathway Contributes To Surround Responses In OFF Retinal Ganglion Cells
Sensory neurons can be influenced by stimuli beyond their receptive field center, yet the mechanisms underlying this surround modulation remain poorly understood. In the retina, many OFF ganglion cell...
www.biorxiv.org
October 7, 2025 at 12:19 PM
🚨 New preprint out from our lab!
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
📄 The Rod Bipolar Cell Pathway Contributes to Surround Responses in OFF Retinal Ganglion Cells
👉 www.biorxiv.org/content/10.1...
Our paper is out today! In @tiffmschmidt.bsky.social lab, we identified a single transcription factor, BRN3B, that shapes multiple, key features that define diverse ipRGC subtypes🧬👁️🐭
Genetic tuning of retinal ganglion cell subtype identity to drive visual behavior
Nature Communications - This study reveals that graded expression of the transcription factor BRN3B fine-tunes the identity and function of melanopsin-expressing ipRGC subtypes in the retina....
urldefense.com
September 30, 2025 at 9:52 PM
Our paper is out today! In @tiffmschmidt.bsky.social lab, we identified a single transcription factor, BRN3B, that shapes multiple, key features that define diverse ipRGC subtypes🧬👁️🐭
Reposted by Marcos Aranda
In case this is helpful for anyone, here is a post on how to get a job in french academia : trialsanderrors.substack.com/p/getting-a-...
Aimed at non-french scientists who are curious, but french ones may find it useful too.
Aimed at non-french scientists who are curious, but french ones may find it useful too.
June 3, 2025 at 4:41 PM
In case this is helpful for anyone, here is a post on how to get a job in french academia : trialsanderrors.substack.com/p/getting-a-...
Aimed at non-french scientists who are curious, but french ones may find it useful too.
Aimed at non-french scientists who are curious, but french ones may find it useful too.
Reposted by Marcos Aranda
Delighted to announce this spring semester's programme for our Seminar Series "Current Topics in Circadian & Visual Neuroscience", featuring a roster of speakers discussing their cutting-edge research in vision and/or circadian rhythms. Register now!
www.tscnlab.org/seminar
www.tscnlab.org/seminar
April 21, 2025 at 11:41 AM
Delighted to announce this spring semester's programme for our Seminar Series "Current Topics in Circadian & Visual Neuroscience", featuring a roster of speakers discussing their cutting-edge research in vision and/or circadian rhythms. Register now!
www.tscnlab.org/seminar
www.tscnlab.org/seminar
Reposted by Marcos Aranda
The ON/OFF dichotomy is fundamental to visual processing. In a new study led by Flori Soto, we identify a conserved molecular mechanism establishing the OFF pathway. rdcu.be/eikoa
Molecular mechanism establishing the OFF pathway in vision
Nature Communications - LRFN2 in cone photoreceptors is vital for building the OFF pathway. Here authors report this cell-adhesion molecule stabilizes contacts with OFF bipolar cells, clusters...
rdcu.be
April 21, 2025 at 12:12 PM
The ON/OFF dichotomy is fundamental to visual processing. In a new study led by Flori Soto, we identify a conserved molecular mechanism establishing the OFF pathway. rdcu.be/eikoa
Reposted by Marcos Aranda
Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti...
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning
Avoidance learning—learning to avoid bad outcomes—is an essential survival behavior. Dopamine signals are widely observed in response to aversive stim…
www.sciencedirect.com
April 22, 2025 at 4:17 PM
Pleased to share the final published version of @glopez.bsky.social's work in @currentbiology.bsky.social! www.sciencedirect.com/science/arti...
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
"Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning"
Congrats, Gaby!!!
Reposted by Marcos Aranda
How does the brain work?
Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
🧠📈
Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
🧠📈
April 9, 2025 at 3:03 PM
How does the brain work?
Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
🧠📈
Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
🧠📈
Reposted by Marcos Aranda
🚨 New preprint alert! 🚨
My first work as a last author is out! 🧵⬇️
We explore how the mouse retina responds to UV & green light and why achieving the right natural illumination is crucial for accurately studying color vision.
By Filippo Castellani, Awen Louboutin & Tom Quétu
doi.org/10.1101/2025...
My first work as a last author is out! 🧵⬇️
We explore how the mouse retina responds to UV & green light and why achieving the right natural illumination is crucial for accurately studying color vision.
By Filippo Castellani, Awen Louboutin & Tom Quétu
doi.org/10.1101/2025...
Accurate spatiotemporal retinal responses require a color intensity balance fine-tuned to natural conditions
Color vision is vital for animal survival, essential for foraging and predator detection. In mice, as in other mammals, color vision originates in the retina, where photoreceptor signals are processed...
doi.org
March 17, 2025 at 2:30 PM
🚨 New preprint alert! 🚨
My first work as a last author is out! 🧵⬇️
We explore how the mouse retina responds to UV & green light and why achieving the right natural illumination is crucial for accurately studying color vision.
By Filippo Castellani, Awen Louboutin & Tom Quétu
doi.org/10.1101/2025...
My first work as a last author is out! 🧵⬇️
We explore how the mouse retina responds to UV & green light and why achieving the right natural illumination is crucial for accurately studying color vision.
By Filippo Castellani, Awen Louboutin & Tom Quétu
doi.org/10.1101/2025...
Reposted by Marcos Aranda
1/ There it is! 😊 Published today in Scientific Reports: www.nature.com/articles/s41...
Spatial distribution and functional integration of displaced retinal ganglion cells - Scientific Reports
Scientific Reports - Spatial distribution and functional integration of displaced retinal ganglion cells
www.nature.com
February 28, 2025 at 1:34 PM
1/ There it is! 😊 Published today in Scientific Reports: www.nature.com/articles/s41...
Reposted by Marcos Aranda
🚨 New paper alert! 🚨
We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species.
A 🧵👇 (1/9)
We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species.
A 🧵👇 (1/9)
March 14, 2025 at 9:41 AM
🚨 New paper alert! 🚨
We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species.
A 🧵👇 (1/9)
We’ve just launched openretina, an open-source framework for collaborative retina modeling across datasets and species.
A 🧵👇 (1/9)
Reposted by Marcos Aranda
A US judge has blocked a policy that would have, beginning today, slashed billions of dollars of funding annually for US research institutions, including universities and hospitals.
https://go.nature.com/4hvSeto
https://go.nature.com/4hvSeto
‘Devastating’ cuts to NIH grants by Trump’s team put on hold by US judge
The ruling temporarily halts a policy slashing research overhead costs in 22 states, which filed a lawsuit against the biomedical agency.
go.nature.com
February 11, 2025 at 1:55 AM
A US judge has blocked a policy that would have, beginning today, slashed billions of dollars of funding annually for US research institutions, including universities and hospitals.
https://go.nature.com/4hvSeto
https://go.nature.com/4hvSeto
Reposted by Marcos Aranda
Our latest preprint about spectroscopic properties of unique #coral #opsins has been uploaded on bioRxiv.
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning|
www.biorxiv.org/content/10.1...
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning|
www.biorxiv.org/content/10.1...
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning
Animal opsins are G protein coupled receptors that have evolved to sense light by covalently binding a retinal chromophore via a protonated (positively charged) Schiff base. A negatively charged amino...
www.biorxiv.org
December 18, 2024 at 5:53 PM
Our latest preprint about spectroscopic properties of unique #coral #opsins has been uploaded on bioRxiv.
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning|
www.biorxiv.org/content/10.1...
Coral anthozoan-specific opsins employ a novel chloride counterion for spectral tuning|
www.biorxiv.org/content/10.1...