Marcel Werner
@marcelwerner.bsky.social
Postdoc at @grothlab.bsky.social and Danish Cancer Institute. PhD at @hamperllab.bsky.social. Interested in DNA replication, epigenetics, and chromatin.
Pinned
Marcel Werner
@marcelwerner.bsky.social
· Feb 20
Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery
Abstract. Progressing transcription and replication machineries profoundly impact their underlying chromatin template. Consequently, transcription-replicat
academic.oup.com
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Reposted by Marcel Werner
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
Repair of DNA double-strand breaks leaves heritable impairment to genome function
Upon DNA breakage, a genomic locus undergoes alterations in three-dimensional chromatin architecture to facilitate signaling and repair. Although cells possess mechanisms to repair damaged DNA, it is ...
tinyurl.com
November 6, 2025 at 11:05 PM
𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
Reposted by Marcel Werner
Histone acetylation - not always about transcriptional activation: H4K16ac safeguards the genome replication program by repressing premature replication of heterochromatin. Well done Marta Milan! tinyurl.com/yuy9m8t3
September 30, 2025 at 12:14 PM
Histone acetylation - not always about transcriptional activation: H4K16ac safeguards the genome replication program by repressing premature replication of heterochromatin. Well done Marta Milan! tinyurl.com/yuy9m8t3
Reposted by Marcel Werner
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
August 28, 2025 at 5:35 PM
We have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute!
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
PhDone!
Last week, an incredible journey of 4.5 years came to an end when I defended my PhD at the LMU in Munich. I am tremendously grateful for all the fun moments throughout this chapter, full of learning and doing cool science.
Last week, an incredible journey of 4.5 years came to an end when I defended my PhD at the LMU in Munich. I am tremendously grateful for all the fun moments throughout this chapter, full of learning and doing cool science.
August 17, 2025 at 11:15 AM
PhDone!
Last week, an incredible journey of 4.5 years came to an end when I defended my PhD at the LMU in Munich. I am tremendously grateful for all the fun moments throughout this chapter, full of learning and doing cool science.
Last week, an incredible journey of 4.5 years came to an end when I defended my PhD at the LMU in Munich. I am tremendously grateful for all the fun moments throughout this chapter, full of learning and doing cool science.
Great work from @ioannistsirkas.bsky.social and the @hamperllab.bsky.social!
Our latest research is online in the @biorxivpreprint.bsky.social! 🧬🎉
🔎 We have developed a novel, single-cell real-time approach to monitor R-loop generated TRCs, and we have shown R-loop-mediated, replisome-controlled transcription repression.
www.biorxiv.org/cgi/content/...
🔎 We have developed a novel, single-cell real-time approach to monitor R-loop generated TRCs, and we have shown R-loop-mediated, replisome-controlled transcription repression.
www.biorxiv.org/cgi/content/...
Replisome progression regulates R-loop mediated transcriptional repression
Maintaining cellular proliferation necessitates the synchronized activity of diverse molecular machineries operating in parallel on the genome. Wide-spread transcription and R-loop formation can inter...
www.biorxiv.org
August 4, 2025 at 10:30 PM
Great work from @ioannistsirkas.bsky.social and the @hamperllab.bsky.social!
Great overview on some of the recent work from my PhD lab! @hamperllab.bsky.social
🔬 Stephan Hamperl uncovered how clashes between #gene reading & #DNA copying inside cells drive disease. Their tools reveal new insights into #cancer, ageing & development.
Read more 👉 europa.eu/!H7RtjQ
#FrontierResearch #GeneEditing #Genetics #Oncology @www.helmholtz-munich.de
Read more 👉 europa.eu/!H7RtjQ
#FrontierResearch #GeneEditing #Genetics #Oncology @www.helmholtz-munich.de
Revealing cellular conflict role in disease and development
Understanding the conflicts that happen within our cells could shed new light not only on disease progression, but also on how our bodies...
europa.eu
July 29, 2025 at 8:21 AM
Great overview on some of the recent work from my PhD lab! @hamperllab.bsky.social
Reposted by Marcel Werner
Linker histone expression is uniquely controlled by a specific pathway, which can be manipulated to increase TOP2i sensitivity! Proud to share first authorship on our story now out in @cp-molcell.bsky.social. www.cell.com/molecular-ce...
CRAMP1-dependent histone H1 biogenesis is essential for topoisomerase II inhibitor tolerance
Ingham et al. identify a dedicated H1 linker histone biogenesis pathway in human cells,
driven by the protein CRAMP1 that functions as an H1 transcription factor. They demonstrate
that defective CRAMP...
www.cell.com
June 19, 2025 at 6:39 AM
Linker histone expression is uniquely controlled by a specific pathway, which can be manipulated to increase TOP2i sensitivity! Proud to share first authorship on our story now out in @cp-molcell.bsky.social. www.cell.com/molecular-ce...
Reposted by Marcel Werner
Are you @ the late stages of your postdoc ? Want to pursue a PI career ?
Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum
www.helmholtz-munich.de/en/stem-cell...
Peer-networking / Career orientation and more !!!
Please distribute :) 🙂
Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum
www.helmholtz-munich.de/en/stem-cell...
Peer-networking / Career orientation and more !!!
Please distribute :) 🙂
June 12, 2025 at 12:58 PM
Are you @ the late stages of your postdoc ? Want to pursue a PI career ?
Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum
www.helmholtz-munich.de/en/stem-cell...
Peer-networking / Career orientation and more !!!
Please distribute :) 🙂
Then this 👇👇 is for you ! Apply for a spot @ our Talent Forum
www.helmholtz-munich.de/en/stem-cell...
Peer-networking / Career orientation and more !!!
Please distribute :) 🙂
Reposted by Marcel Werner
Delighted to share that the results of my main postdoc project are now published in @nature.com
🔗 doi.org/10.1038/s415...
🔗 doi.org/10.1038/s415...
Multigenerational cell tracking of DNA replication and heritable DNA damage - Nature
A multigenerational single-cell tracking approach provides a framework to dissect phenotypic plasticity at the single-cell level, offering insights into cellular processes that may resemble early even...
doi.org
May 21, 2025 at 3:27 PM
Delighted to share that the results of my main postdoc project are now published in @nature.com
🔗 doi.org/10.1038/s415...
🔗 doi.org/10.1038/s415...
Reposted by Marcel Werner
🚨 Postdoc wanted (🇳🇱NL based) for our exciting collaboration with the lab of Alexander van Oudenaarden @hubrechtinstitute.bsky.social in Utrecht, with collaborative visits to our lab Copenhagen 🇩🇰. We seek a computational scientist to model epigenetic inheritance, see more below 👇!
🧬Postdoc position alert! 🚨 We're hiring a postoc in Computational Modeling of Epigenetic Inheritance at the Hubrecht Institute (Alexander van Oudenaarden, Utrecht 🇳🇱) & Danish Cancer Institute (Anja Groth, Copenhagen 🇩🇰).
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Postdoctoral Researcher - Computational modeling of Epigenetic Inheritance - 38 hours p/w - Hubrecht Institute
About the Project Faithful inheritance of the epigenome in proliferating cells critically underpins human development and health. While DNA replication fidelity and DNA mutation rates are well underst...
shorturl.at
May 20, 2025 at 10:20 AM
🚨 Postdoc wanted (🇳🇱NL based) for our exciting collaboration with the lab of Alexander van Oudenaarden @hubrechtinstitute.bsky.social in Utrecht, with collaborative visits to our lab Copenhagen 🇩🇰. We seek a computational scientist to model epigenetic inheritance, see more below 👇!
Reposted by Marcel Werner
🧬Postdoc position alert! 🚨 We're hiring a postoc in Computational Modeling of Epigenetic Inheritance at the Hubrecht Institute (Alexander van Oudenaarden, Utrecht 🇳🇱) & Danish Cancer Institute (Anja Groth, Copenhagen 🇩🇰).
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Postdoctoral Researcher - Computational modeling of Epigenetic Inheritance - 38 hours p/w - Hubrecht Institute
About the Project Faithful inheritance of the epigenome in proliferating cells critically underpins human development and health. While DNA replication fidelity and DNA mutation rates are well underst...
shorturl.at
May 16, 2025 at 7:45 AM
🧬Postdoc position alert! 🚨 We're hiring a postoc in Computational Modeling of Epigenetic Inheritance at the Hubrecht Institute (Alexander van Oudenaarden, Utrecht 🇳🇱) & Danish Cancer Institute (Anja Groth, Copenhagen 🇩🇰).
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Come work in our collaberative team of top scientists
shorturl.at/avBBy
Delighted to share that I am joining @grothlab.bsky.social and @groth-anja.bsky.social at Danish Cancer Institute for my postdoc. 🇩🇰
I am looking forward to working on advancing our understanding of epigenome replication and maintenance. 🧬🧫
I am looking forward to working on advancing our understanding of epigenome replication and maintenance. 🧬🧫
May 1, 2025 at 1:32 PM
Delighted to share that I am joining @grothlab.bsky.social and @groth-anja.bsky.social at Danish Cancer Institute for my postdoc. 🇩🇰
I am looking forward to working on advancing our understanding of epigenome replication and maintenance. 🧬🧫
I am looking forward to working on advancing our understanding of epigenome replication and maintenance. 🧬🧫
Reposted by Marcel Werner
Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:
April 14, 2025 at 4:56 PM
Thrilled to see my postdoc work at Adelman Lab @hms-bcmp.bsky.social on Integrator(INT) now out @cp-cell.bsky.social. We found that INT deficiency allows immature+unlicensed RNAPII to precociously enter genes. This immature RNAPII can transcribe short genes but terminates prematurely in long genes:
Reposted by Marcel Werner
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
April 6, 2025 at 9:45 AM
🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
Reposted by Marcel Werner
🌟 SAVE THE DATE: Talent Forum 2025!
🗓️ November 18–19
📍 @www.helmholtz-munich.de, Germany
Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research!
Apply by July 31 for a speaker spot —travel & accommodation covered.
🔜 Website coming soon!
🗓️ November 18–19
📍 @www.helmholtz-munich.de, Germany
Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research!
Apply by July 31 for a speaker spot —travel & accommodation covered.
🔜 Website coming soon!
March 25, 2025 at 11:02 AM
🌟 SAVE THE DATE: Talent Forum 2025!
🗓️ November 18–19
📍 @www.helmholtz-munich.de, Germany
Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research!
Apply by July 31 for a speaker spot —travel & accommodation covered.
🔜 Website coming soon!
🗓️ November 18–19
📍 @www.helmholtz-munich.de, Germany
Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research!
Apply by July 31 for a speaker spot —travel & accommodation covered.
🔜 Website coming soon!
Goodbye @hamperllab.bsky.social and thank you for incredible 4.5 years! It has been a pleasure to work with all of you and I will miss you a lot. Thank you also to @epihmgu.bsky.social and the Munich chromatin community. I could not have picked a better place to do my PhD!
To new adventures! 🇩🇰
To new adventures! 🇩🇰
April 3, 2025 at 1:42 PM
Goodbye @hamperllab.bsky.social and thank you for incredible 4.5 years! It has been a pleasure to work with all of you and I will miss you a lot. Thank you also to @epihmgu.bsky.social and the Munich chromatin community. I could not have picked a better place to do my PhD!
To new adventures! 🇩🇰
To new adventures! 🇩🇰
Reposted by Marcel Werner
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
tinyurl.com
March 28, 2025 at 3:51 PM
A few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
Reposted by Marcel Werner
Two days of science, international cooking, and breathtaking hikes in the Bavarian Alps—our lab retreat in Mittenwald had it all! Great discussions, great food, and even better company.
March 24, 2025 at 11:38 AM
Two days of science, international cooking, and breathtaking hikes in the Bavarian Alps—our lab retreat in Mittenwald had it all! Great discussions, great food, and even better company.
Reposted by Marcel Werner
🚨Paper Alert!
👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work!
🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability.
A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work!
🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability.
A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery
Abstract. Progressing transcription and replication machineries profoundly impact their underlying chromatin template. Consequently, transcription-replicat
academic.oup.com
March 18, 2025 at 5:08 PM
🚨Paper Alert!
👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work!
🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability.
A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work!
🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability.
A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
Reposted by Marcel Werner
𝐍𝐞𝐰 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐢𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐡𝐢𝐬𝐭𝐨𝐧𝐞 𝐬𝐮𝐩𝐩𝐥𝐲! Excited to share our latest collaboration led by tkjeong.bsky.social and ciaranfrater.bsky.social! Structural determination of the histone chaperone ASF1 and its regulator CODANIN-1 uncovers how CODANIN-1 counters ASF1 activity. 🧵👇
CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate the histone supply
Nature Communications - CODANIN-1 negatively regulates the function of ASF1, the key chaperone for histone H3-H4 supply. Here the authors present the cryo-EM structure of the CODANIN-1_ASF1A...
rdcu.be
March 6, 2025 at 12:45 PM
𝐍𝐞𝐰 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐢𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐡𝐢𝐬𝐭𝐨𝐧𝐞 𝐬𝐮𝐩𝐩𝐥𝐲! Excited to share our latest collaboration led by tkjeong.bsky.social and ciaranfrater.bsky.social! Structural determination of the histone chaperone ASF1 and its regulator CODANIN-1 uncovers how CODANIN-1 counters ASF1 activity. 🧵👇
Reposted by Marcel Werner
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
DNA replication and genome maintenance: from basic biology to disease
www.embl.org
February 26, 2025 at 3:22 PM
SAVE THE DATE! The next EMBO | EMBL Symposium on 'DNA replication and genome maintenance: from basic biology to disease' will be held October 20-23, 2026.
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
Organized by Helle Ulrich (IMB), Johannes Walter (Harvard) and Anja Groth (Danish Cancer Institute).
www.embl.org/about/info/c...
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Transcription-replication conflicts drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery
Abstract. Progressing transcription and replication machineries profoundly impact their underlying chromatin template. Consequently, transcription-replicat
academic.oup.com
February 20, 2025 at 1:38 PM
I am delighted to share the main work of my PhD project in the @hamperllab.bsky.social now out in @narjournal.bsky.social. TRCs drive R-loop-dependent nucleosome eviction and require DOT1L activity for transcription recovery.
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
academic.oup.com/nar/article/...
#TRC #r-loop #chromatin
More below 👇
Reposted by Marcel Werner
𝐇𝐨𝐰 𝐝𝐨 𝐜𝐞𝐥𝐥𝐬 𝐫𝐞𝐦𝐞𝐦𝐛𝐞𝐫 𝐰𝐡𝐨 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐟𝐭𝐞𝐫 𝐃𝐍𝐀 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧? Our new study “Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability” is out in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴. Led by @lleonie.bsky.social @biranalva.bsky.social 🧵 More below👇
Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability
Losing parental histones during DNA replication fork passage challenges differentiation competence and cell viability.
tinyurl.com
February 19, 2025 at 7:35 PM
𝐇𝐨𝐰 𝐝𝐨 𝐜𝐞𝐥𝐥𝐬 𝐫𝐞𝐦𝐞𝐦𝐛𝐞𝐫 𝐰𝐡𝐨 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐟𝐭𝐞𝐫 𝐃𝐍𝐀 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧? Our new study “Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability” is out in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴. Led by @lleonie.bsky.social @biranalva.bsky.social 🧵 More below👇
Reposted by Marcel Werner
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
6 Postdoctoral and PhD positions in Center for Epigenetic Cell Memory (EpiC)
The Center for Epigenetic Cell Memory (EpiC) is a new Center of Excellence that will be established based on funding by the Danish National Research Foundation.
tinyurl.com
February 12, 2025 at 2:53 PM
🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
Reposted by Marcel Werner
I am thrilled to share that our latest pre-print from the @evahoermanseder.bsky.social lab 🐸🧬, is now online! Check it out here:
www.biorxiv.org/content/10.1...
Highlights and key findings from our study in the thread below 👇
www.biorxiv.org/content/10.1...
Highlights and key findings from our study in the thread below 👇
Digital Reprogramming Decodes Epigenetic Barriers of Cell Fate Changes
Fates of differentiated cells in our body can be induced to change by nuclear reprogramming. In this way, cells valuable for therapeutic purposes and disease modeling can be produced. However, the eff...
www.biorxiv.org
January 26, 2025 at 12:10 PM
I am thrilled to share that our latest pre-print from the @evahoermanseder.bsky.social lab 🐸🧬, is now online! Check it out here:
www.biorxiv.org/content/10.1...
Highlights and key findings from our study in the thread below 👇
www.biorxiv.org/content/10.1...
Highlights and key findings from our study in the thread below 👇