loosolab
loosolab.bsky.social
loosolab
@loosolab.bsky.social
Bioinformatics lab at the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany
Reposted by loosolab
🔬How a Blood Vessel Protein Puts Tumor Cells to Sleep!
Our researchers from our Pharmacology team have identified a key membrane protein -PEAR1- found in blood vessel cells that plays a crucial role in keeping disseminated tumor cells in a dormant, non-dividing state.

Read paper: shorturl.at/2HHzk
November 21, 2025 at 8:40 AM
Reposted by loosolab
Check this from the talented and unimitable Bibli lab

"Nuclear cystine oxidation boosts acetyl-CoA, decorating histones and opening chromatin"
www.cell.com/cell-metabol...
www.cell.com
November 3, 2025 at 7:46 AM
Reposted by loosolab
🚀 Call for Applications - CPI Postdoc Grants

You want to shape the future of heart and lung research? We are seeking talented, ambitious postdocs to join our interdisciplinary team of over 200 scientists. Deadline: Oct 31!

Details and how to apply: cpi-online.de/academy-post... #ResearchGrant
September 25, 2025 at 11:59 AM
📢 Paper Alert: Now in Briefings in Bioinformatics and scverse (
@scverse.bsky.social
)!
PEAKQC, a Python package for robust QC of single-cell ATAC-seq data, identifies high-quality cells accurately.
academic.oup.com/bib/article/...
PEAKQC: periodicity evaluation in single-cell ATAC-seq data for quality assessment
Abstract. Chromatin organization guides gene regulatory mechanisms and has been subject of extensive research using chromatin accessibility assays. ATAC-se
academic.oup.com
September 16, 2025 at 6:06 PM
🚀 Two exciting days of Computational Biology at the Cardio-Pulmonary Institute in Bad Nauheim @cpi-exstra.bsky.social ! 🔬 Workshop on single-cell analysis + the CPI repository data ressource; 💡 Hackathon together with the Schulz Lab @themarcelschulz.bsky.social
Collaboration, coding & discovery
August 28, 2025 at 12:07 PM
🚀 Just released: Multicrispr², an R package for gRNA library design!
✅ Single & paired gRNAs
✅ Prime editing
✅ Scales to large target sets
✅ Multitude of parameters
Perfect for high-throughput CRISPR designs

bioinformatics-cluster2.mpi-bn.mpg.de/multicrispr2...

#CRISPR #Bioinformatics #Pertomics
Multicrispr2Frontend
bioinformatics-cluster2.mpi-bn.mpg.de
July 15, 2025 at 12:11 PM
Code fest alert! Our Bioinformatics Core unit at MPI HLR is hosting a Hackathon today! Our team is working together to improve automated reports, streamline workflows, and enhance our CPI repository (@cpi-exstra.bsky.social). #Bioinformatics #Hackathon #MPI_hlr"
June 25, 2025 at 1:55 PM
🎉 Congratulations to Moritz on the launch of NucleoDetective, his tool for chromatin research! 🧬 Presented at the @EMBLEvents
#EMBLChromatin — and awarded the Poster Prize by community vote! 🏆
#CPI_ExStra #Epigenetics #Chromatin
May 21, 2025 at 8:32 AM