Lucas K. Bobadilla
@lkbobadilla.bsky.social
Genomic Data Scientist at Corteva Agriscience
BS at University of Sao Paulo, MS at Oregon State University , PhD at the University of Illinois; Views are my own.
Brazilian living in America playing with genomic data
BS at University of Sao Paulo, MS at Oregon State University , PhD at the University of Illinois; Views are my own.
Brazilian living in America playing with genomic data
Reposted by Lucas K. Bobadilla
Tagging 🧪 🧬🖥️
Sad news:
The dataset behind this famous chart on the decline in costs of genome sequencing has had its NIH funding cut.
I loved this chart because it was the first that made me appreciate the impact of dataviz. But it also tracked progress towards an ambitious goal ($1000 genome) that succeeded.
The dataset behind this famous chart on the decline in costs of genome sequencing has had its NIH funding cut.
I loved this chart because it was the first that made me appreciate the impact of dataviz. But it also tracked progress towards an ambitious goal ($1000 genome) that succeeded.
![The "$1,000 genome" catchphrase was first publicly recorded in December 2001 at a scientific retreat to discuss the future of biomedical research following publication of the first draft of the Human Genome Project (HGP), convened by the National Human Genome Research Institute at Airlie House in Virginia.[5] The phrase neatly highlighted the chasm between the actual cost of the Human Genome Project, estimated at $2.7 billion over a decade, and the benchmark for routine, affordable personal genome sequencing.
On 2 October 2002, Craig Venter introduced the opening session of GSAC (The Genome Sequencing and Analysis Conference) at the Hynes Convention Center in Boston: "The Future of Sequencing: Advancing Towards the $1,000 Genome." Speakers included George M. Church and executives from 454 Life Sciences, Solexa, U.S. Genomics, VisiGen and Amersham plc.[6][7] In 2003, Venter announced that his foundation would earmark $500,000 for a breakthrough leading to the $1,000 genome.[8] That sum was subsequently rolled into the Archon X Prize.
In October 2004, NHGRI introduced the first in a series of '$1,000 Genome' grants designed to advance "the development of breakthrough technologies that will enable a human-sized genome to be sequenced for $1,000 or less."[9]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:73aicoale2mqwrap63rdzwep/bafkreigcypk33xduk2wsfjyvwbnfzzb76p5m6jl3owhbb3ft32clwov37i@jpeg)
July 19, 2025 at 1:28 PM
Tagging 🧪 🧬🖥️
Sad to see this amazing research program at #UIUC on #soybean and #plantscience getting shut down. This happened because of the stupidity of closing #USAID. This type of things will hit US farmers pretty hard…
February 13, 2025 at 1:01 AM
Sad to see this amazing research program at #UIUC on #soybean and #plantscience getting shut down. This happened because of the stupidity of closing #USAID. This type of things will hit US farmers pretty hard…
Reposted by Lucas K. Bobadilla
Minimap2-rs v0.1.22 has released! This only fixes a memory segfault under certain conditions. I have added some better examples for using mpsc channels or rayon.
github.com/jguhlin/mini...
#rust #rustlang #bioinformatics #genomics #nanopore #pacbio
github.com/jguhlin/mini...
#rust #rustlang #bioinformatics #genomics #nanopore #pacbio
minimap2-rs/examples at main · jguhlin/minimap2-rs
Rust bindings to minimap2 library. Contribute to jguhlin/minimap2-rs development by creating an account on GitHub.
github.com
December 3, 2024 at 9:44 PM
Minimap2-rs v0.1.22 has released! This only fixes a memory segfault under certain conditions. I have added some better examples for using mpsc channels or rayon.
github.com/jguhlin/mini...
#rust #rustlang #bioinformatics #genomics #nanopore #pacbio
github.com/jguhlin/mini...
#rust #rustlang #bioinformatics #genomics #nanopore #pacbio
Reposted by Lucas K. Bobadilla
📜 Trade-offs involved in the choice of pot vs field experiments
🧑🔬 Daniel Montesinos
📔 @newphyt.bsky.social
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/...
#️⃣ #PlantScience #PlantPhysiology #PlantDevelopment #PlantImmunity
🧑🔬 Daniel Montesinos
📔 @newphyt.bsky.social
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/...
#️⃣ #PlantScience #PlantPhysiology #PlantDevelopment #PlantImmunity
Trade‐offs involved in the choice of pot vs field experiments
Click on the article title to read more.
nph.onlinelibrary.wiley.com
November 21, 2024 at 11:30 AM
📜 Trade-offs involved in the choice of pot vs field experiments
🧑🔬 Daniel Montesinos
📔 @newphyt.bsky.social
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/...
#️⃣ #PlantScience #PlantPhysiology #PlantDevelopment #PlantImmunity
🧑🔬 Daniel Montesinos
📔 @newphyt.bsky.social
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/...
#️⃣ #PlantScience #PlantPhysiology #PlantDevelopment #PlantImmunity
Think your abstract is short?? Think again, this abstract as only 2 words: “probably not” (and it is enough lol) #academics 🧬
arxiv.org/abs/1110.2832
arxiv.org/abs/1110.2832
Can apparent superluminal neutrino speeds be explained as a quantum weak measurement?
Probably not.
arxiv.org
November 21, 2024 at 2:25 PM
Think your abstract is short?? Think again, this abstract as only 2 words: “probably not” (and it is enough lol) #academics 🧬
arxiv.org/abs/1110.2832
arxiv.org/abs/1110.2832
Reposted by Lucas K. Bobadilla
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 4:20 PM
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
Very true. Science is a collaborative effort and does not have space for individualism
Doing good science is 90% finding a science buddy to constantly talk to about the project.
November 18, 2024 at 1:53 AM
Very true. Science is a collaborative effort and does not have space for individualism
Reposted by Lucas K. Bobadilla
Hello, since the requests to be added to the #PlantScience Research #StarterPack keep coming, I have created a 2nd Pack. So, here are
Part 1:
go.bsky.app/8Zfmwf7
Part 2:
go.bsky.app/3NcqRCE
Part 1:
go.bsky.app/8Zfmwf7
Part 2:
go.bsky.app/3NcqRCE
November 16, 2024 at 7:43 PM
Hello, since the requests to be added to the #PlantScience Research #StarterPack keep coming, I have created a 2nd Pack. So, here are
Part 1:
go.bsky.app/8Zfmwf7
Part 2:
go.bsky.app/3NcqRCE
Part 1:
go.bsky.app/8Zfmwf7
Part 2:
go.bsky.app/3NcqRCE
Looking for a free #AI and #machinelearning course to start learning about it? Elements of AI is a cool system I am using to teach high school kids. Also, you can get a certificate for doing it!
www.elementsofai.com
www.elementsofai.com
A free online introduction to artificial intelligence for non-experts
Learn more about MinnaLearn's and the University of Helsinki's AI course - no programming or complicated math required.
www.elementsofai.com
November 16, 2024 at 5:11 PM
Looking for a free #AI and #machinelearning course to start learning about it? Elements of AI is a cool system I am using to teach high school kids. Also, you can get a certificate for doing it!
www.elementsofai.com
www.elementsofai.com
Evo DNA 🧬 model was just published on Science very cool model architecture using hybrid blocks with long context.
www.science.org/toc/science/...
www.science.org/toc/science/...
Contents | Science 386, 6723
www.science.org
November 15, 2024 at 1:54 AM
Evo DNA 🧬 model was just published on Science very cool model architecture using hybrid blocks with long context.
www.science.org/toc/science/...
www.science.org/toc/science/...
Reposted by Lucas K. Bobadilla
Looks like Bryan Dickinson isn’t here yet so I’m cross posting his challenge:
“if you or someone you know thinks they can actually predict PPIs, prove it. Here is a link to our blinded protein sequence data”
dickinsonlab.uchicago.edu/ppi-challenge
“if you or someone you know thinks they can actually predict PPIs, prove it. Here is a link to our blinded protein sequence data”
dickinsonlab.uchicago.edu/ppi-challenge
PPI Challenge | dickinson-group
dickinsonlab.uchicago.edu
November 14, 2024 at 12:01 AM
Looks like Bryan Dickinson isn’t here yet so I’m cross posting his challenge:
“if you or someone you know thinks they can actually predict PPIs, prove it. Here is a link to our blinded protein sequence data”
dickinsonlab.uchicago.edu/ppi-challenge
“if you or someone you know thinks they can actually predict PPIs, prove it. Here is a link to our blinded protein sequence data”
dickinsonlab.uchicago.edu/ppi-challenge
My daily life this last few weeks
Don't look at the news
Don't look at the news
Don't look at the news
(Looks at the news)
Oh, for fuck's sake
Don't look at the news
Don't look at the news
(Looks at the news)
Oh, for fuck's sake
November 14, 2024 at 1:36 AM
My daily life this last few weeks
Bluesky now has over 10 million users, and I was #1,021,069!
September 28, 2024 at 3:45 PM
Bluesky now has over 10 million users, and I was #1,021,069!
I need this!
One of the few Twitter accounts I miss is MachinePix, run by Kane Hsieh. Here's a tribute, in honor of Bluesky getting video (and doing my part to test the servers).
First: Twelve-legged walking "Carpentopod" table by Giliam de Carpentier www.decarpentier.nl/carpentopod
First: Twelve-legged walking "Carpentopod" table by Giliam de Carpentier www.decarpentier.nl/carpentopod
September 12, 2024 at 2:00 PM
I need this!
Reposted by Lucas K. Bobadilla
big night for transgender illegal aliens who eat cats
September 11, 2024 at 3:24 AM
big night for transgender illegal aliens who eat cats
Manager: so you don’t have a plan?
Data Scientist: I have concepts of a plan
#debate #datascience #programming
Data Scientist: I have concepts of a plan
#debate #datascience #programming
September 11, 2024 at 3:29 AM
Manager: so you don’t have a plan?
Data Scientist: I have concepts of a plan
#debate #datascience #programming
Data Scientist: I have concepts of a plan
#debate #datascience #programming
Reposted by Lucas K. Bobadilla
I am looking for people who want be co-author/co-maintainer of my repo of examples and e-book 'py2rs' - A guide for the Pythonista in the process of becoming a Rustacean - https://rochacbruno.github.io/py2rs/ #python #rust
September 10, 2024 at 6:09 PM
I am looking for people who want be co-author/co-maintainer of my repo of examples and e-book 'py2rs' - A guide for the Pythonista in the process of becoming a Rustacean - https://rochacbruno.github.io/py2rs/ #python #rust
#langchain and #pythonprogramming people: does anyone know a tool that improves the model conversion of the user input into a SPARQL query?
September 9, 2024 at 4:45 PM
#langchain and #pythonprogramming people: does anyone know a tool that improves the model conversion of the user input into a SPARQL query?
Learning #Rust definitely is paying off. I was able to create my custom applications for #bioinformatics and also applying those with some #Python pipelines. #Rustlang is not easy but once you get used to it is a great language! 🧬🖥️🧪
September 8, 2024 at 8:19 PM
Learning #Rust definitely is paying off. I was able to create my custom applications for #bioinformatics and also applying those with some #Python pipelines. #Rustlang is not easy but once you get used to it is a great language! 🧬🖥️🧪
Reposted by Lucas K. Bobadilla
Reposted by Lucas K. Bobadilla
I'm hiring! Currently accepting applications for center coordinator, bioinformatics engineer/scientist, and postdoctoral researcher. Please share with those that might be interested: genomeinformatics.github.io/jobs2024/
The NHGRI Center for Genomics and Data Science Research is hiring!
Join our team and contribute to the development of complete, personalized “telomere-to-telomere” (T2T) genome assemblies and the analysis of previously inaccessible regions of the genome! We are curre...
genomeinformatics.github.io
August 13, 2024 at 8:53 PM
I'm hiring! Currently accepting applications for center coordinator, bioinformatics engineer/scientist, and postdoctoral researcher. Please share with those that might be interested: genomeinformatics.github.io/jobs2024/
August 30, 2024 at 11:46 PM
Reposted by Lucas K. Bobadilla
aqui vamos nós! bem-vindo ao Bluesky!
aqui estão algumas respostas para perguntas comuns. estamos muito animados em ter você aqui 🤗
aqui estão algumas respostas para perguntas comuns. estamos muito animados em ter você aqui 🤗
Perguntas Frequentes do Usuário Bluesky (Português) - Bluesky
Bem-vindo ao aplicativo Bluesky! Este é um guia do usuário que responde a algumas perguntas comuns.
bsky.social
August 30, 2024 at 8:39 PM
aqui vamos nós! bem-vindo ao Bluesky!
aqui estão algumas respostas para perguntas comuns. estamos muito animados em ter você aqui 🤗
aqui estão algumas respostas para perguntas comuns. estamos muito animados em ter você aqui 🤗