Vishnu Girish
@liveloveliver.bsky.social
Hepatologist | Living the liver life | Advocate for free education | One liver at a time | Celebrating uniqueness, against discrimination #Liversky
ur latest in Clinical and Molecular Hepatology is out: “Tracking the trajectory of kidney dysfunction in cirrhosis: the AKI–CKD spectrum.”
time to rethink kidney injury as a continuum.
pubmed.ncbi.nlm.nih.gov/40138802/
time to rethink kidney injury as a continuum.
pubmed.ncbi.nlm.nih.gov/40138802/
April 1, 2025 at 6:39 AM
ur latest in Clinical and Molecular Hepatology is out: “Tracking the trajectory of kidney dysfunction in cirrhosis: the AKI–CKD spectrum.”
time to rethink kidney injury as a continuum.
pubmed.ncbi.nlm.nih.gov/40138802/
time to rethink kidney injury as a continuum.
pubmed.ncbi.nlm.nih.gov/40138802/
#GISky High lipase but no pancreatitis, what now?
Reference: PMID 38817657
Reference: PMID 38817657
February 2, 2025 at 2:13 PM
Reposted by Vishnu Girish
A new #PSC review from @f8martine.bsky.social , et al.
PSC-IBD is probably a distinct form of IBD with UC and Crohn's.
"on a molecular level, almost all people with PSC have underlying colitis"
2024 = 100th anniversary of the description of PSC
journals.lww.com/hep/abstract...
#liversky
PSC-IBD is probably a distinct form of IBD with UC and Crohn's.
"on a molecular level, almost all people with PSC have underlying colitis"
2024 = 100th anniversary of the description of PSC
journals.lww.com/hep/abstract...
#liversky
PSC and colitis: A complex relationship : Hepatology
an extraintestinal manifestation of IBD, the clinical phenotype, genetic and intestinal microbiota associations strongly argue for PSC-IBD being a distinct form of IBD, existing alongside ulcerative c...
journals.lww.com
January 29, 2025 at 4:05 PM
A new #PSC review from @f8martine.bsky.social , et al.
PSC-IBD is probably a distinct form of IBD with UC and Crohn's.
"on a molecular level, almost all people with PSC have underlying colitis"
2024 = 100th anniversary of the description of PSC
journals.lww.com/hep/abstract...
#liversky
PSC-IBD is probably a distinct form of IBD with UC and Crohn's.
"on a molecular level, almost all people with PSC have underlying colitis"
2024 = 100th anniversary of the description of PSC
journals.lww.com/hep/abstract...
#liversky
Reposted by Vishnu Girish
🧪New paper on immune signatures in alcohol-related liver disease (ALD):
⬆️Accumulation of CD4 T cells
🧬CD4 T cells marked by GZMK, tissue-resident signature
🎯GZMK+CD4+ T cells in fibrotic zones
🔑Immune cell populations in ALD may be key
#liversky
www.cmghjournal.org/article/S235...
⬆️Accumulation of CD4 T cells
🧬CD4 T cells marked by GZMK, tissue-resident signature
🎯GZMK+CD4+ T cells in fibrotic zones
🔑Immune cell populations in ALD may be key
#liversky
www.cmghjournal.org/article/S235...
Single-cell Profiling of Intrahepatic Immune Cells Reveals an Expansion of Tissue-resident Cytotoxic CD4+ T Lymphocyte Subset Associated With Pathogenesis of Alcoholic-associated Liver Diseases
The immunological mechanisms underpinning the pathogenesis of alcoholic-associated
liver disease (ALD) remain incompletely elucidated. This study aims to explore the
transcriptomic profiles of hepatic...
www.cmghjournal.org
January 29, 2025 at 6:02 PM
🧪New paper on immune signatures in alcohol-related liver disease (ALD):
⬆️Accumulation of CD4 T cells
🧬CD4 T cells marked by GZMK, tissue-resident signature
🎯GZMK+CD4+ T cells in fibrotic zones
🔑Immune cell populations in ALD may be key
#liversky
www.cmghjournal.org/article/S235...
⬆️Accumulation of CD4 T cells
🧬CD4 T cells marked by GZMK, tissue-resident signature
🎯GZMK+CD4+ T cells in fibrotic zones
🔑Immune cell populations in ALD may be key
#liversky
www.cmghjournal.org/article/S235...
Reposted by Vishnu Girish
🆕 AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals
@amergastroassn.bsky.social
#IDsky #Liversky
www.gastrojournal.org/action/showP...
@amergastroassn.bsky.social
#IDsky #Liversky
www.gastrojournal.org/action/showP...
January 30, 2025 at 3:56 AM
🆕 AGA Clinical Practice Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation in At-Risk Individuals
@amergastroassn.bsky.social
#IDsky #Liversky
www.gastrojournal.org/action/showP...
@amergastroassn.bsky.social
#IDsky #Liversky
www.gastrojournal.org/action/showP...
Reposted by Vishnu Girish
Admittedly the cool name of the study group first caught my 👁️
POSEIDON study group showed
✅alfapump 📉need for LVP
✅similar complications
✅improved QOL
@amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
#liversky
POSEIDON study group showed
✅alfapump 📉need for LVP
✅similar complications
✅improved QOL
@amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
#liversky
January 6, 2025 at 4:44 PM
Admittedly the cool name of the study group first caught my 👁️
POSEIDON study group showed
✅alfapump 📉need for LVP
✅similar complications
✅improved QOL
@amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
#liversky
POSEIDON study group showed
✅alfapump 📉need for LVP
✅similar complications
✅improved QOL
@amcollegegastro.bsky.social
journals.lww.com/ajg/abstract...
#liversky
Reposted by Vishnu Girish
Pleased that #FARGO - a randomised, multicentre, placebo-controlled phase IIa trial of #FMT to treat #PSC - is running and recruiting. Have a look at the protocol paper out now in #BMJOpen: doi.org/10.1136/bmjo... @pscsupport.bsky.social @cholestasisdoc.bsky.social
FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trial
Introduction Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD). The strong association between gut and liver inflammation has driven...
doi.org
January 7, 2025 at 7:30 AM
Pleased that #FARGO - a randomised, multicentre, placebo-controlled phase IIa trial of #FMT to treat #PSC - is running and recruiting. Have a look at the protocol paper out now in #BMJOpen: doi.org/10.1136/bmjo... @pscsupport.bsky.social @cholestasisdoc.bsky.social
📢Thrilled to share our latest review article. Greatful to Prof. Rakhi Maiwall. We explore challenges of managing septic shock in cirrhosis and advocate for personalized approaches
pubmed.ncbi.nlm.nih.gov/39744868/
#liversky #Medsky #GIsky
@anandvkulkarni.bsky.social
pubmed.ncbi.nlm.nih.gov/39744868/
#liversky #Medsky #GIsky
@anandvkulkarni.bsky.social
January 4, 2025 at 2:12 AM
📢Thrilled to share our latest review article. Greatful to Prof. Rakhi Maiwall. We explore challenges of managing septic shock in cirrhosis and advocate for personalized approaches
pubmed.ncbi.nlm.nih.gov/39744868/
#liversky #Medsky #GIsky
@anandvkulkarni.bsky.social
pubmed.ncbi.nlm.nih.gov/39744868/
#liversky #Medsky #GIsky
@anandvkulkarni.bsky.social
Reposted by Vishnu Girish
Great look into the future on HCC surveillance by George Ioannou at AASLD #TLM24
Seems likely that blood based biomarkers and aMRI will play some role but, despite its significant flaws, ultrasound has so far stood the test of time
Seems likely that blood based biomarkers and aMRI will play some role but, despite its significant flaws, ultrasound has so far stood the test of time
November 16, 2024 at 2:45 PM
Great look into the future on HCC surveillance by George Ioannou at AASLD #TLM24
Seems likely that blood based biomarkers and aMRI will play some role but, despite its significant flaws, ultrasound has so far stood the test of time
Seems likely that blood based biomarkers and aMRI will play some role but, despite its significant flaws, ultrasound has so far stood the test of time
Reposted by Vishnu Girish
Did you know...
There are nifty one page summaries of selected ACG guidelines available at gi.org/guidelines
Just click on the "Summary" tab under the guidelines
Here are some examples with many more in development
#GISky #LiverSky
There are nifty one page summaries of selected ACG guidelines available at gi.org/guidelines
Just click on the "Summary" tab under the guidelines
Here are some examples with many more in development
#GISky #LiverSky
November 13, 2024 at 4:04 PM
Did you know...
There are nifty one page summaries of selected ACG guidelines available at gi.org/guidelines
Just click on the "Summary" tab under the guidelines
Here are some examples with many more in development
#GISky #LiverSky
There are nifty one page summaries of selected ACG guidelines available at gi.org/guidelines
Just click on the "Summary" tab under the guidelines
Here are some examples with many more in development
#GISky #LiverSky