Andreas Linkermann
@linkermannlab.bsky.social
Chair 5th Med Dept UMM, Heidelberg University
Kidney Transplantation and Cell Death Biology
Kidney Transplantation and Cell Death Biology
Pinned
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature
17β-oestradiol establishes an anti-ferroptotic state in female kidney tubules.
www.nature.com
Happy to start at Bluesky with a post on our recent manuscript at @nature.com:
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E - Gavali - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...
advanced.onlinelibrary.wiley.com
November 4, 2025 at 11:57 AM
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E - Gavali - Advanced Science - Wiley Online Library advanced.onlinelibrary.wiley.com/doi/10.1002/...
Very pleased to share this "spotlight" in Trends in Endocrinology and Metabolism which refers to our recent work.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Hydroxyestradiol alleviates acute kidney injury via blockade of ferroptosis
The molecular mechanisms underlying sex differences in acute kidney injury (AKI) remain incompletely understood. In a study recently published in Natu…
www.sciencedirect.com
September 17, 2025 at 7:34 PM
Very pleased to share this "spotlight" in Trends in Endocrinology and Metabolism which refers to our recent work.
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Here is a "highlight" on our recent work written by Boyi Gan for Cell Death and Differentiation:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury - Cell Death & Differentiation
Cell Death & Differentiation - Oestradiol-mediated ferroptosis defense shapes sex differences in acute kidney injury
www.nature.com
August 31, 2025 at 6:19 AM
Here is a "highlight" on our recent work written by Boyi Gan for Cell Death and Differentiation:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
This refers to our recent manuscript.
Estrogen-powered kidney protection | Science Signaling www.science.org/doi/10.1126/...
Estrogen-powered kidney protection | Science Signaling www.science.org/doi/10.1126/...
Estrogen-powered kidney protection
Estrogen protects against kidney injury through both genomic and nongenomic mechanisms.
www.science.org
August 27, 2025 at 11:42 AM
This refers to our recent manuscript.
Estrogen-powered kidney protection | Science Signaling www.science.org/doi/10.1126/...
Estrogen-powered kidney protection | Science Signaling www.science.org/doi/10.1126/...
STING drives #necroptosis, and here’s how it does it!
Congratulations to @gianmaria-liccardi.bsky.social and his amazing team!
www.nature.com/articles/s41...
Congratulations to @gianmaria-liccardi.bsky.social and his amazing team!
www.nature.com/articles/s41...
STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD - Nature
Nature - STING induces ZBP1-mediated necroptosis independently of TNFR1 and FADD
www.nature.com
August 20, 2025 at 11:31 PM
STING drives #necroptosis, and here’s how it does it!
Congratulations to @gianmaria-liccardi.bsky.social and his amazing team!
www.nature.com/articles/s41...
Congratulations to @gianmaria-liccardi.bsky.social and his amazing team!
www.nature.com/articles/s41...
Happy to start at Bluesky with a post on our recent manuscript at @nature.com:
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury - Nature
17β-oestradiol establishes an anti-ferroptotic state in female kidney tubules.
www.nature.com
August 19, 2025 at 8:57 AM
Happy to start at Bluesky with a post on our recent manuscript at @nature.com:
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
www.nature.com/articles/s41...
Great collaboration with cool scientists such as @theprattgroup.bsky.social, @fedorovalab.bsky.social and many who do not (yet) have a Bluesky account.
Reposted by Andreas Linkermann
Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV
August 18, 2025 at 3:42 PM
Hot off the presses! Was an honor to team up with Scott Dixon @stanforduniversity.bsky.social on this Nature Cancer review. We reflect on hurdles that have slowed translation of ferroptosis-directed therapies and share ideas on what it will take to bring these therapies to the clinic. rdcu.be/eBbqV