Tim Lee
@leetim.bsky.social
Neuroscientist and engineer. Studying spatial navigation in the miniature translucent fish Danionella cerebrum. Postdoc in Briggman Lab at MPINB.
Reposted by Tim Lee
Why do some worms graze on bacteria while others hunt and kill?
Our study, published today in Nature, reveals how predatory aggression evolved in nematodes.
Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
Our study, published today in Nature, reveals how predatory aggression evolved in nematodes.
Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
Predatory aggression evolved through adaptations to noradrenergic circuits - Nature
Noradrenergic circuits support and balance aggressive behavioural states in predatory nematodes, distinguish predatory from non-predatory nematode species and are associated with the evolution of comp...
www.nature.com
January 21, 2026 at 4:31 PM
Why do some worms graze on bacteria while others hunt and kill?
Our study, published today in Nature, reveals how predatory aggression evolved in nematodes.
Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
Our study, published today in Nature, reveals how predatory aggression evolved in nematodes.
Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
Reposted by Tim Lee
1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here:
rdcu.be/eX1L4
rdcu.be/eX1L4
Plastic landmark anchoring in zebrafish compass neurons
Nature - Using two-photon microscopy with a panoramic virtual reality setup, how head direction cells in larval zebrafish integrate visual landmarks and optic flow to track orientation is revealed.
rdcu.be
January 7, 2026 at 8:53 PM
1/6: New publication from the lab: “Plastic landmark anchoring in zebrafish compass neurons” by Ryosuke Tanaka (@ryosuketanaka.bsky.social) and Ruben is available here:
rdcu.be/eX1L4
rdcu.be/eX1L4
Reposted by Tim Lee
PhD position in systems neuroscience!
Excited to start a new DFG-funded project together with @obarnstedt.bsky.social to study olfactory–spatial coding in CA1.
🔬 Dual-colour miniscope Ca2+ imaging
🐭 Freely moving behaviour & optogenetics
⏳ Start: April 2026 | Deadline: 31.01.2026
More info below ⬇️
Excited to start a new DFG-funded project together with @obarnstedt.bsky.social to study olfactory–spatial coding in CA1.
🔬 Dual-colour miniscope Ca2+ imaging
🐭 Freely moving behaviour & optogenetics
⏳ Start: April 2026 | Deadline: 31.01.2026
More info below ⬇️
December 11, 2025 at 10:56 AM
PhD position in systems neuroscience!
Excited to start a new DFG-funded project together with @obarnstedt.bsky.social to study olfactory–spatial coding in CA1.
🔬 Dual-colour miniscope Ca2+ imaging
🐭 Freely moving behaviour & optogenetics
⏳ Start: April 2026 | Deadline: 31.01.2026
More info below ⬇️
Excited to start a new DFG-funded project together with @obarnstedt.bsky.social to study olfactory–spatial coding in CA1.
🔬 Dual-colour miniscope Ca2+ imaging
🐭 Freely moving behaviour & optogenetics
⏳ Start: April 2026 | Deadline: 31.01.2026
More info below ⬇️
Reposted by Tim Lee
Our Method of the Year 2025 is...drumroll please...EM-based connectomics!!
Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬
www.nature.com/articles/s41...
Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬
www.nature.com/articles/s41...
Method of the Year 2025: electron microscopy-based connectomics - Nature Methods
A large network of interconnected neurons serves as the basis of brain function and of behavior. Methodological advances have enabled the reconstruction of large-scale and even whole-brain connectomes...
www.nature.com
December 8, 2025 at 4:59 PM
Our Method of the Year 2025 is...drumroll please...EM-based connectomics!!
Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬
www.nature.com/articles/s41...
Our Editorial introduces our choice and highlights six Comments and other related content in this special issue. Please join us in celebrating EM-based connectomics! 🎉🧠🔬
www.nature.com/articles/s41...
Reposted by Tim Lee
Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41...
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)
November 27, 2025 at 4:40 AM
Our new paper showcasing molecular connectomics with pan-expansion microscopy is out in @natbiotech.nature.com! www.nature.com/articles/s41...
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)
This wonderful collaboration with @bewersdorflab.bsky.social was led by Ons M'Saad (now founder/CEO of Panluminate) and @allisonphysics.bsky.social. (1/5)
Reposted by Tim Lee
PhD position on fear response in zebrafish in a new and exciting lab working with Dr. Emmanuel Marquez Legorreta. He's a great scientist and super nice guy, I highly recommend him
www.uu.nl/en/organisat...
www.uu.nl/en/organisat...
PhD position in Neuroscience
Reveal the neuronal populations underlying innate fear responses using whole-brain imaging of neuronal activity and gene expression in larval zebrafish!
www.uu.nl
November 21, 2025 at 8:25 AM
PhD position on fear response in zebrafish in a new and exciting lab working with Dr. Emmanuel Marquez Legorreta. He's a great scientist and super nice guy, I highly recommend him
www.uu.nl/en/organisat...
www.uu.nl/en/organisat...
Reposted by Tim Lee
Thanks Misha for the shout-out!
It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.
It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.
Preprint -
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
Excited to present WHOLISTIC, which extends the concept of whole-brain functional imaging to the entire body. Pioneering work by incredibly talented Virginia Ruetten @vmsruetten.bsky.social, this platform reveals whole-organism cellular dynamics in vivo.
www.biorxiv.org/content/10.1...
September 8, 2025 at 4:30 PM
Thanks Misha for the shout-out!
It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.
It has been a truly mind-opening journey. WHOLISTIC is one step towards whole-organism neuroscience and a true physiological observatory - with extensions on the way! I am continually amazed by what the data reveals - so much remains to be discovered and mined.
Reposted by Tim Lee
Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
September 8, 2025 at 12:00 PM
Application is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
Reposted by Tim Lee
🚨 PhD alert! IMPRS brain & behavior in Bonn just opened their calls for applications. Great PhD funding opportunities. Check it out! PS- I just joined their faculty, meaning you could do a rotation in my lab or even a PhD with me on spider sleep 🙃 Apply! 🚨
📢Apply now! Join our IMPRS for Brain&Behavior to pursue a #PhD in #neuroethology. Learn how brain circuits are linked to interesting animal behaviors!
📅 Deadline: October 31, 2025
🔗 imprs-brain-behavior.mpg.de
#neuroscience #Neuroskyence #neurojobs #sciencejobs #PhDsky #PhDOffers #FundedPhD
📅 Deadline: October 31, 2025
🔗 imprs-brain-behavior.mpg.de
#neuroscience #Neuroskyence #neurojobs #sciencejobs #PhDsky #PhDOffers #FundedPhD
September 6, 2025 at 8:48 AM
🚨 PhD alert! IMPRS brain & behavior in Bonn just opened their calls for applications. Great PhD funding opportunities. Check it out! PS- I just joined their faculty, meaning you could do a rotation in my lab or even a PhD with me on spider sleep 🙃 Apply! 🚨
Reposted by Tim Lee
It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!)
thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.
thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.
August 14, 2025 at 7:40 PM
It was a good experience to step back and briefly take stock of the amazing progress in connectomics since I started working on this stuff (20 years ago!)
thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.
thanks as well to @natrevneuro.nature.com for the constructive editorial interactions.
Reposted by Tim Lee
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
August 1, 2025 at 9:06 AM
Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. ➡️ mpg.de/directors - Please share the Open Call among potential candidates.
Reposted by Tim Lee
Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...
Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution
Understanding the evolution of the bilaterian brain requires a detailed exploration of the precise nature of cellular and subcellular differences between related species. We undertook an electron micr...
www.science.org
July 31, 2025 at 6:42 PM
Happy to share our publication - Comparative connectomics of two distantly related nematode species reveals patterns of nervous system evolution www.science.org/doi/10.1126/...
Reposted by Tim Lee
New preprint from @darbly.bsky.social @briandepasquale.bsky.social and my labs! If you love (or hate) mosquitoes, have a look:
doi.org/10.1101/2025...
We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
doi.org/10.1101/2025...
We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
Recurrent connectivity supports carbon dioxide sensitivity in Aedes aegypti mosquitoes
The mosquito Aedes aegypti′s human host-seeking behavior depends on the integration of multiple sensory cues. One of these cues, carbon dioxide (CO2), gates odorant and heat pathways and activates hos...
doi.org
July 31, 2025 at 12:28 PM
New preprint from @darbly.bsky.social @briandepasquale.bsky.social and my labs! If you love (or hate) mosquitoes, have a look:
doi.org/10.1101/2025...
We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
doi.org/10.1101/2025...
We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
Reposted by Tim Lee
@natrevneuro.nature.com just published a beautiful cover for the issue that includes the recent review on analogies in the visual system of vertebrates and invertebrates (@ryosuketanaka.bsky.social). Read it here doi.org/10.1038/s415...
Science and Art, what could be better?
Science and Art, what could be better?
July 23, 2025 at 4:43 PM
@natrevneuro.nature.com just published a beautiful cover for the issue that includes the recent review on analogies in the visual system of vertebrates and invertebrates (@ryosuketanaka.bsky.social). Read it here doi.org/10.1038/s415...
Science and Art, what could be better?
Science and Art, what could be better?
Reposted by Tim Lee
🚀 New Neurovoyagers episode just dropped!
It's been such a great time chatting with @monikakscholz.bsky.social about worms, neural bottlenecks, open science, and the joy of building stuff that works 🧠🔧
🎧 open.spotify.com/episode/1r2a...
It's been such a great time chatting with @monikakscholz.bsky.social about worms, neural bottlenecks, open science, and the joy of building stuff that works 🧠🔧
🎧 open.spotify.com/episode/1r2a...
Brains in Miniature: Evolution, Foraging, and Open Science with Monika Scholz
Neurovoyagers: Exploring the Minds Behind Neuroscience · Episode
open.spotify.com
June 12, 2025 at 6:51 AM
🚀 New Neurovoyagers episode just dropped!
It's been such a great time chatting with @monikakscholz.bsky.social about worms, neural bottlenecks, open science, and the joy of building stuff that works 🧠🔧
🎧 open.spotify.com/episode/1r2a...
It's been such a great time chatting with @monikakscholz.bsky.social about worms, neural bottlenecks, open science, and the joy of building stuff that works 🧠🔧
🎧 open.spotify.com/episode/1r2a...
Reposted by Tim Lee
Are you interested in visual systems? How are they similar or different across species? Read the review by Ryosuke @ryosuketanaka.bsky.social and Ruben published today in @natrevneuro.nature.com. It is available here: rdcu.be/enlpC
May 23, 2025 at 4:19 PM
Are you interested in visual systems? How are they similar or different across species? Read the review by Ryosuke @ryosuketanaka.bsky.social and Ruben published today in @natrevneuro.nature.com. It is available here: rdcu.be/enlpC
Reposted by Tim Lee
So great to see this in print! Congratulations to Johannes and team!
Read our news article from our research group Neural Circuits mpinb.mpg.de/en/research-...
Or the full paper 👉 www.nature.com/articles/s41...
#Neuroethology #Sleep #Glia #WatchingAFlysBrain
Or the full paper 👉 www.nature.com/articles/s41...
#Neuroethology #Sleep #Glia #WatchingAFlysBrain
Dynamics of glia and neurons regulate homeostatic rest, sleep and feeding behavior in Drosophila - Nature Neuroscience
Animals alternate between active periods and periods of rest or sleep. This study in fruit flies points to brain metabolism as a cause for this and shows that a network of glial cells interacting with...
www.nature.com
April 21, 2025 at 11:55 AM
So great to see this in print! Congratulations to Johannes and team!
Reposted by Tim Lee
Algorithmic dissection of optic flow memory in larval zebrafish https://www.biorxiv.org/content/10.1101/2025.04.15.648832v1
April 20, 2025 at 1:15 AM
Algorithmic dissection of optic flow memory in larval zebrafish https://www.biorxiv.org/content/10.1101/2025.04.15.648832v1
Come join the Briggman lab in beautiful Bonn to work with a menagerie of animals: axolotls, anableps, danionella, zebrafish, xenopus tropicalus and more! Also, the institute is dog-friendly and sits on a dog park! 🐶
🧠 Interested in a postdoc in neuroscience?
Our Department of Computational Neuroethology is hiring for two exciting projects:
🔬 Retinal circuitry evolution
🐟 Mechanistic cognition in Danionella cerebrum
mpinb.mpg.de/en/research-...
📅 Apply by May 13 via the Max Planck #PostdocProgram
#Neuroethology
Our Department of Computational Neuroethology is hiring for two exciting projects:
🔬 Retinal circuitry evolution
🐟 Mechanistic cognition in Danionella cerebrum
mpinb.mpg.de/en/research-...
📅 Apply by May 13 via the Max Planck #PostdocProgram
#Neuroethology
April 16, 2025 at 5:32 AM
Come join the Briggman lab in beautiful Bonn to work with a menagerie of animals: axolotls, anableps, danionella, zebrafish, xenopus tropicalus and more! Also, the institute is dog-friendly and sits on a dog park! 🐶
Reposted by Tim Lee
1/3
Starting this summer, and after 11 wonderful years in Munich, the Portugues Lab will be starting a new adventure at the Department of Neurobiology and Behavior (NBB) (nbb.cornell.edu) at Cornell University in Ithaca, NY.
Starting this summer, and after 11 wonderful years in Munich, the Portugues Lab will be starting a new adventure at the Department of Neurobiology and Behavior (NBB) (nbb.cornell.edu) at Cornell University in Ithaca, NY.
Department of Neurobiology and Behavior | Department of Neurobiology and Behavior
nbb.cornell.edu
April 2, 2025 at 1:01 PM
1/3
Starting this summer, and after 11 wonderful years in Munich, the Portugues Lab will be starting a new adventure at the Department of Neurobiology and Behavior (NBB) (nbb.cornell.edu) at Cornell University in Ithaca, NY.
Starting this summer, and after 11 wonderful years in Munich, the Portugues Lab will be starting a new adventure at the Department of Neurobiology and Behavior (NBB) (nbb.cornell.edu) at Cornell University in Ithaca, NY.
Reposted by Tim Lee
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior https://www.biorxiv.org/content/10.1101/2025.04.01.646316v1
April 1, 2025 at 1:45 PM
A modular multi-color fluorescence microscope for simultaneous tracking of cellular activity and behavior https://www.biorxiv.org/content/10.1101/2025.04.01.646316v1
Reposted by Tim Lee
#Danionella in the creature column www.nature.com/articles/s41...
Danionella fishes - Nature Methods
Miniature, transparent Danionella fishes, which are among the smallest living adult vertebrates, allow investigation of general principles of brain-wide neural circuits and evolutionary and developmen...
www.nature.com
December 4, 2024 at 10:44 PM
#Danionella in the creature column www.nature.com/articles/s41...